Critical Illness

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  Subject Areas on Research

  • "One Piece at a Time": The Cache of Acute Kidney Injury Data in the Electronic Medical Record. 
  • A Framework for Improving Chronic Critical Illness Care: Adapting the Medical Home's Central Tenets. 
  • A Multicenter Randomized Trial of a Checklist for Endotracheal Intubation of Critically Ill Adults. 
  • A National Emergency Airway Registry for children: landscape of tracheal intubation in 15 PICUs. 
  • A case of mistaken identity: persistent sciatic artery stenosis as a cause of critical limb ischemia. 
  • A cost and outcomes comparison of a novel integrated pediatric air and ground transportation system. 
  • A descriptive evaluation of transfusion practices in patients receiving mechanical ventilation. 
  • A few of our favorite unconfirmed ideas. 
  • A novel approach to maintain gut mucosal integrity using an oral enzyme supplement. 
  • A nurse's guide to early detection of umbilical venous catheter complications in infants. 
  • A pilot study to explore the safety of perioperative postpyloric enteral nutrition. 
  • A prognostic model for one-year mortality in patients requiring prolonged mechanical ventilation. 
  • A randomized evaluation of bispectral index-augmented sedation assessment in neurological patients. 
  • A randomized trial of glutamine and antioxidants in critically ill patients. 
  • A randomized trial of supplemental parenteral nutrition in underweight and overweight critically ill patients: the TOP-UP pilot trial. 
  • A review of the use of adjunctive therapies in severe acute asthma exacerbation in critically ill children. 
  • A universal decision support system. Addressing the decision-making needs of patients, families, and clinicians in the setting of critical illness. 
  • ACC/AHA/ASE 2003 guideline update for the clinical application of echocardiography: summary article: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (ACC/AHA/ASE Committee to Update the 1997 Guidelines for the Clinical Application of Echocardiography). 
  • Accidental communities: race, emergency medicine, and the problem of polyheme. 
  • Active rehabilitation during extracorporeal membrane oxygenation as a bridge to lung transplantation. 
  • Addressing Patient Emotional and Existential Needs During Serious Illness: Results of the Outlook Randomized Controlled Trial. 
  • Addressing the Psychological Symptoms of Critical Illness: The Importance of "Negative" Trials in Guiding Next Steps. 
  • Adult emergency department patients with sickle cell pain crisis: a learning collaborative model to improve analgesic management. 
  • Aggressive versus conservative initiation of antimicrobial treatment in critically ill surgical patients with suspected intensive-care-unit-acquired infection: a quasi-experimental, before and after observational cohort study. 
  • Alternative lipid emulsions as a new standard of care for total parenteral nutrition: finally available in the United States?. 
  • An assessment of US physicians' training in religion, spirituality, and medicine. 
  • An expanded series of distal bypass using the distal vein patch technique to improve prosthetic graft performance in critical limb ischemia. 
  • An official American Thoracic Society statement: Treatment of fungal infections in adult pulmonary and critical care patients. 
  • Anesthesia for interventional neuroradiology. 
  • Apolipoprotein E4 polymorphism as a genetic predisposition to delirium in critically ill patients. 
  • Aspergillus infections in transplant and non-transplant surgical patients. 
  • Association between intravenous chloride load during resuscitation and in-hospital mortality among patients with SIRS. 
  • Association between the choice of IV crystalloid and in-hospital mortality among critically ill adults with sepsis*. 
  • Association of an Electroencephalography-Based Risk Score With Seizure Probability in Hospitalized Patients. 
  • Association of gender with outcomes in critically ill patients. 
  • Barriers to enrollment in a randomized controlled trial of hydrocortisone for cardiovascular insufficiency in term and late preterm newborn infants. 
  • Beyond thrombosis: the versatile platelet in critical illness. 
  • Brainstem dysfunction as a predictor of death in the nonneurologically injured. 
  • CE: A Review of Current Practice in Transfusion Therapy. 
  • Care of the Neonatal Intensive Care Unit Graduate after Discharge. 
  • Central nervous system modulation of respiratory function in the critically ill. 
  • Changing preferences for survival after hospitalization with advanced heart failure. 
  • Choice of fluid in acute illness: what should be given? An international consensus. 
  • Choices of seriously ill patients about cardiopulmonary resuscitation: correlates and outcomes. SUPPORT Investigators. Study to Understand Prognoses and Preferences for Outcomes and Risks of Treatments. 
  • Chronic critical illness. 
  • Chronic critical illness: the growing challenge to health care. 
  • Clergy-laity support and patients' mood during serious illness: a cross-sectional epidemiologic study. 
  • Clinical Impact of External Laryngeal Manipulation During Laryngoscopy on Tracheal Intubation Success in Critically Ill Children. 
  • Clinical Momentum in the Intensive Care Unit. A Latent Contributor to Unwanted Care. 
  • Clinical Pharmacology Studies in Critically Ill Children. 
  • Clinical Practice Guidelines From the AABB: Red Blood Cell Transfusion Thresholds and Storage. 
  • Clinical review: Optimizing enteral nutrition for critically ill patients--a simple data-driven formula. 
  • Clinical year in review I: quality improvement for pulmonary and critical care medicine, lung transplantation, rehabilitation for pulmonary and critically ill patients, and sleep medicine. 
  • Cognitive and physical rehabilitation of intensive care unit survivors: results of the RETURN randomized controlled pilot investigation. 
  • Communicating prognosis with parents of critically ill infants: direct observation of clinician behaviors. 
  • Communication practices on 4 Harvard surgical services: a surgical safety collaborative. 
  • Consensus Recommendations for RBC Transfusion Practice in Critically Ill Children From the Pediatric Critical Care Transfusion and Anemia Expertise Initiative. 
  • Consensus statement on continuous EEG in critically ill adults and children, part I: indications. 
  • Consensus statement on continuous EEG in critically ill adults and children, part II: personnel, technical specifications, and clinical practice. 
  • Cost and health care utilization in ARDS--different from other critical illness? 
  • Cost of Medical Care of Patients with Advanced Serious Illness in Singapore (COMPASS): prospective cohort study protocol. 
  • Cricoid Pressure During Induction for Tracheal Intubation in Critically Ill Children: A Report From National Emergency Airway Registry for Children. 
  • Critical care cardiology research: a call to action. 
  • Critical illness hyperglycemia in pediatric cardiac surgery. 
  • Current medication practice and tracheal intubation safety outcomes from a prospective multicenter observational cohort study. 
  • D-dimer levels in VTE patients with distal and proximal clots. 
  • De-Escalation of Antibiotics Does Not Increase Mortality in Critically Ill Surgical Patients. 
  • Defining the Value Proposition for Specialist Palliative Care Delivered in Intensive Care Units. 
  • Definitions of cardiovascular insufficiency and relation to outcomes in critically ill newborn infants. 
  • Delirium in Critically Ill Children: An International Point Prevalence Study. 
  • Delirium is a robust predictor of morbidity and mortality among critically ill patients treated in the cardiac intensive care unit. 
  • Demand-flow airway pressure release ventilation as a partial ventilatory support mode: comparison with synchronized intermittent mandatory ventilation and pressure support ventilation. 
  • Determinants of central sympathetic activation in spontaneous primary subarachnoid hemorrhage. 
  • Development and preliminary evaluation of a telephone-based mindfulness training intervention for survivors of critical illness. 
  • Development and validation of a printed information brochure for families of chronically critically ill patients. 
  • Development and validation of a seizure prediction model in critically ill children. 
  • Differences in blood pressure by measurement technique in neurocritically ill patients: A technological assessment. 
  • Differences in one-year health outcomes and resource utilization by definition of prolonged mechanical ventilation: a prospective cohort study. 
  • Does artificial nutrition improve outcome of critical illness? An alternative viewpoint! 
  • Duplex ultrasound screening detects high rates of deep vein thromboses in critically ill trauma patients. 
  • Early mobilization in critically ill patients: patients' mobilization level depends on health care provider's profession. 
  • Economic evaluation of propofol and lorazepam for critically ill patients undergoing mechanical ventilation. 
  • Effect of Location on Tracheal Intubation Safety in Cardiac Disease-Are Cardiac ICUs Safer? 
  • Effect of Palliative Care-Led Meetings for Families of Patients With Chronic Critical Illness: A Randomized Clinical Trial. 
  • Effectiveness of right heart catheterization: time for a randomized trial. 
  • Effects of a Personalized Web-Based Decision Aid for Surrogate Decision Makers of Patients With Prolonged Mechanical Ventilation: A Randomized Clinical Trial. 
  • Effects of a Telephone- and Web-based Coping Skills Training Program Compared with an Education Program for Survivors of Critical Illness and Their Family Members. A Randomized Clinical Trial. 
  • Effects of gender on the health and development of medically at-risk infants. 
  • Effects of maternal depressive symptoms and infant gender on the interactions between mothers and their medically at-risk infants. 
  • Effects of mindfulness training programmes delivered by a self-directed mobile app and by telephone compared with an education programme for survivors of critical illness: a pilot randomised clinical trial. 
  • Effects of pharmaconutrients on cellular dysfunction and the microcirculation in critical illness. 
  • Electroencephalography monitoring in critically ill children: current practice and implications for future study design. 
  • Elevated admission N-terminal pro-brain natriuretic peptide level predicts the development of atrial fibrillation in general surgical intensive care unit patients. 
  • End-stage renal disease and intensive care unit prognosis: are current tools good enough? 
  • Engaging Survivors of Critical Illness in Health Care Assessment and Policy Development. Ethical and Practical Complexities. 
  • Ensuring Optimal Survival and Post-ICU Quality of Life in High-Risk ICU Patients: Permissive Underfeeding Is Not Safe! 
  • Enteral fish oil in critical illness: perspectives and systematic review. 
  • Erythromycin vs metoclopramide for facilitating gastric emptying and tolerance to intragastric nutrition in critically ill patients. 
  • Estimates of future physical functioning by seriously ill hospitalized patients, their families, and their physicians. 
  • Ethical and regulatory challenges associated with the exception from informed consent requirements for emergency research: from experimental design to institutional review board approval. 
  • Evaluating a critically ill patient with metabolic acidosis: the ifosfamide paradigm. 
  • Evolving approaches to assessing and monitoring patient-ventilator interactions. 
  • Examination of QTc Values in Critically Ill Patients Diagnosed with Delirium and Prescribed Atypical Antipsychotics. 
  • Exploring the vagueness of Religion & Spirituality in complex pediatric decision-making: a qualitative study. 
  • Extracellular Mitochondrial DNA and N-Formyl Peptides in Trauma and Critical Illness: A Systematic Review. 
  • Extracorporeal membrane oxygenation for severe refractory respiratory failure secondary to 2009 H1N1 influenza A. 
  • Facing persistent challenges in pediatric decision-making: new Hastings Center guidelines. 
  • Fibroblast Growth Factor 23 Associates with Death in Critically Ill Patients. 
  • Fibroblast Growth Factor 23 Levels Associate with AKI and Death in Critical Illness. 
  • Fluconazole population pharmacokinetics and dosing for prevention and treatment of invasive Candidiasis in children supported with extracorporeal membrane oxygenation. 
  • Fluids are drugs: type, dose and toxicity. 
  • Frequency of Desaturation and Association With Hemodynamic Adverse Events During Tracheal Intubations in PICUs. 
  • Fulminant pertussis: a multi-center study with new insights into the clinico-pathological mechanisms. 
  • Gastric motility function in critically ill patients tolerant vs intolerant to gastric nutrition. 
  • Gastropexy using the Carter-Thomason device in lieu of T-fasteners in a critically ill, severely obese patient: an innovative technique. 
  • Gender disparities in adult health: an examination of three measures of morbidity. 
  • Glutamine Supplementation in Parenteral Nutrition and Intensive Care Unit Patients: Are We Throwing the Baby Out With the Bathwater? 
  • Glutamine and antioxidants in the critically ill patient: a post hoc analysis of a large-scale randomized trial. 
  • Glutamine attenuates tumor necrosis factor-alpha release and enhances heat shock protein 72 in human peripheral blood mononuclear cells. 
  • Glutamine in critical illness: the time has come, the time is now. 
  • Glutamine-mediated attenuation of cellular metabolic dysfunction and cell death after injury is dependent on heat shock factor-1 expression. 
  • Glutamine. 
  • Glutamine: mode of action in critical illness. 
  • Glutamine: role in critical illness and ongoing clinical trials. 
  • Glutamine: role in gut protection in critical illness. 
  • Glutamine: the first clinically relevant pharmacological regulator of heat shock protein expression? 
  • Glycemic control in patients undergoing coronary artery bypass graft surgery: Clinical features, predictors, and outcomes. 
  • Goal-directed or goal-misdirected - how should we interpret the literature? 
  • Health values of the seriously ill. 
  • Health values of the seriously ill. SUPPORT investigators. 
  • How Surrogate Decision-Makers for Patients With Chronic Critical Illness Perceive and Carry Out Their Role. 
  • Hydroxyethyl starch or saline in intensive care. 
  • Hyperglycemia-related mortality in critically ill patients varies with admission diagnosis. 
  • Hypocaloric compared with eucaloric nutritional support and its effect on infection rates in a surgical intensive care unit: a randomized controlled trial. 
  • Hyponatremia and the use of vasopressin receptor antagonists in critically ill patients. 
  • ICU procedures of the critically ill. 
  • Identifying pediatric emergence delirium by using the PAED Scale: a quality improvement project. 
  • Impact of red blood cell transfusion on global and regional measures of oxygenation. 
  • Impact of the pulmonary artery catheter in critically ill patients: meta-analysis of randomized clinical trials. 
  • Improving post-intensive care unit neuropsychiatric outcomes: understanding cognitive effects of physical activity. 
  • Incidence and Risk Factors for Intensive Care Unit-related Post-traumatic Stress Disorder in Veterans and Civilians. 
  • Incidence and risk factors for venous thromboembolism in critically ill children after trauma. 
  • Incidence, management, and outcomes of cardiovascular insufficiency in critically ill term and late preterm newborn infants. 
  • Increased Occurrence of Tracheal Intubation-Associated Events During Nights and Weekends in the PICU. 
  • Increases of cardiac troponin in conditions other than acute coronary syndrome and heart failure. 
  • Inflammasome expression and cytomegalovirus viremia in critically ill patients with sepsis. 
  • Influence of donor base deficit status on recipient outcomes in liver transplantation. 
  • Influence of stress and nursing leadership on job satisfaction of pediatric intensive care unit nurses. 
  • Inhibitory effects of hyperglycemia on neural activity of the vagus in rats. 
  • Insulin-like growth factor 1 and delirium. 
  • Intensity of renal support in critically ill patients with acute kidney injury. 
  • Intensive insulin therapy in critically ill patients. 
  • Intensive insulin therapy in the neurocritical care setting is associated with poor clinical outcomes. 
  • Interleukin-1 receptor-associated kinase-1: more evidence. 
  • Intrahospital Transport of the Critically Ill Adult: A Standardized Evaluation Plan. 
  • Is it time for individualized thromboprophylaxis regimens in the ICU? 
  • Is there a difference in bloodstream infections in critically ill patients associated with ready-to-use versus compounded parenteral nutrition? 
  • Is there still a role for high-frequency oscillatory ventilation in neonates, children and adults? 
  • Lacosamide in status epilepticus: Update on the TRENdS study. 
  • Life threatening liver disease during treatment with monoclonal antibodies. 
  • Life-saving treatments and disabilities. Are all QALYs created equal? 
  • Literature review and global consensus on management of acute radiation syndrome affecting nonhematopoietic organ systems. 
  • Measurement of high-sensitivity troponin T in noncardiac medical intensive care unit patients. Correlation to mortality and length of stay. 
  • Measurement of quality and assurance of safety in the critically ill. 
  • Measuring Adaptive Coping of Hospitalized Patients With a Severe Medical Condition: The Sickness Insight in Coping Questionnaire. 
  • Measuring the effect of inappropriate initial antibiotic therapy on outcomes of patients with Gram-negative sepsis: An imprecise science. 
  • Mechanical Ventilator Discontinuation Process. 
  • Medical and economic implications of prolonged mechanical ventilation and expedited post-acute care. 
  • Metabolic and nutritional support of critically ill patients: consensus and controversies. 
  • Metabolomic derangements are associated with mortality in critically ill adult patients. 
  • Methodologic Challenges in the Diagnosis of Acute Kidney Injury in Children With Diabetic Ketoacidosis. 
  • Misconceptions concerning gastroesophageal reflux in children. 
  • Model for End-Stage Liver Disease score predicts mortality in critically ill cirrhotic patients. 
  • Models of Peer Support to Remediate Post-Intensive Care Syndrome: A Report Developed by the Society of Critical Care Medicine Thrive International Peer Support Collaborative. 
  • Molecular Mechanisms Linking Autonomic Dysfunction and Impaired Cardiac Contractility in Critical Illness. 
  • Monitoring oxygen delivery in the critically ill. 
  • Mortality and religion/spirituality: a brief review of the research. 
  • Muscle mass and physical recovery in ICU: innovations for targeting of nutrition and exercise. 
  • National Academy of Clinical Biochemistry laboratory medicine practice guidelines: use of cardiac troponin and B-type natriuretic peptide or N-terminal proB-type natriuretic peptide for etiologies other than acute coronary syndromes and heart failure. 
  • Natriuretic peptide testing for the evaluation of critically ill patients with shock in the intensive care unit: a prospective cohort study. 
  • Neurologic and Functional Morbidity in Critically Ill Children With Bronchiolitis. 
  • New-onset atrial fibrillation is associated with increased mortality in critically ill patients: a systematic review and meta-analysis. 
  • No question too small: development of a question prompt list for parents of critically ill infants. 
  • Nocturnal Dexmedetomidine in Nonintubated, Critically Ill Patients: Sleep or Sedation? 
  • Non invasive monitoring in mechanically ventilated pediatric patients. 
  • Nontraditional modes of mechanical ventilation: progress or distraction? 
  • Nurse perception of Bispectral Index monitoring as an adjunct to sedation scale assessment in the critically ill paediatric patient. 
  • Nutrition Therapy in Sepsis. 
  • Nutrition assessment of the critically ill adult. 
  • Nutrition therapy for the critically ill surgical patient: we need to do better! 
  • Nutrition therapy in critically ill infants and children. 
  • Nutritional support in critically ill patients. 
  • Older age, aggressiveness of care, and survival for seriously ill, hospitalized adults. SUPPORT Investigators. Study to Understand Prognoses and Preferences for Outcomes and Risks of Treatments. 
  • Omeprozole therapy in pediatric patients after liver and intestinal transplantation. 
  • One Size Does Not Fit All: Disease Profiles of Serious Illness Patients Receiving Specialty Palliative Care. 
  • One-year trajectories of care and resource utilization for recipients of prolonged mechanical ventilation: a cohort study. 
  • Operationalizing the Measuring What Matters Spirituality Quality Metric in a Population of Hospitalized, Critically Ill Patients and Their Family Members. 
  • Optimizing energy and protein balance in the ICU. 
  • Optimizing the dose of glutamine dipeptides and antioxidants in critically ill patients: a phase I dose-finding study. 
  • Organ cross talk in the critically ill: the heart and kidney. 
  • Organ donation and treatment of the multi-organ donor. 
  • Organ protective mechanisms common to extremes of physiology: a window through hibernation biology. 
  • Oscillating Continuous Cardiac Output in Postoperative Critically Ill Patients: Is this Phenomenon Accurate, Artifact, or Error? 
  • Outcome of liver transplantation in critically ill patients with alcoholic cirrhosis: survival according to medical variables and sobriety. 
  • Oxygen in Acute Illness: More or Less? 
  • Oxygen: Providing Too Much of a Good Thing? 
  • PLX-PAD Cell Treatment of Critical Limb Ischaemia: Rationale and Design of the PACE Trial. 
  • Palliative Care Planner: A Pilot Study to Evaluate Acceptability and Usability of an Electronic Health Records System-integrated, Needs-targeted App Platform. 
  • Parenteral glutamine increases serum heat shock protein 70 in critically ill patients. 
  • Parenteral nutrition and calorie delivery in the ICU: controversy, clarity, or call to action? 
  • Patient race and decisions to withhold or withdraw life-sustaining treatments for seriously ill hospitalized adults. SUPPORT Investigators. Study to Understand Prognoses and Preferences for Outcomes and Risks of Treatments. 
  • Patterns of Sedation Weaning in Critically Ill Children Recovering From Acute Respiratory Failure. 
  • Pediatric Acute Respiratory Distress Syndrome in Pediatric Allogeneic Hematopoietic Stem Cell Transplants: A Multicenter Study. 
  • Pediatric cardiovascular drug dosing in critically ill children and extracorporeal membrane oxygenation. 
  • Performance of the Paediatric Index of Mortality 3 and Paediatric Logistic Organ Dysfunction 2 Scores in Critically Ill Children. 
  • Performance-enhancing sports supplements: role in critical care. 
  • Peripheral vascular complications during transcatheter aortic valve replacement: management and potential role of chronic steroid use. 
  • Persistent systemic inflammation in chronic critical illness. 
  • Pharmacodynamics and pharmacokinetics of milrinone administration to increase oxygen delivery in critically ill patients. 
  • Pharmacokinetics and Dosing of Anti-infective Drugs in Patients on Extracorporeal Membrane Oxygenation: A Review of the Current Literature. 
  • Pharmaconutrition and nutrition therapy in critical illness. Preface. 
  • Pharmaconutrition review: physiological mechanisms. 
  • Physician Decision-Making in the Setting of Advanced Illness: An Examination of Patient Disposition and Physician Religiousness. 
  • Physiology and regulation. Ionized calcium, magnesium and lactate measurements in critical care settings. 
  • Potential Cost-effectiveness of Early Identification of Hospital-acquired Infection in Critically Ill Patients. 
  • Precision Medicine for Critical Illness and Injury. 
  • Predicting critical illness mortality and personalizing therapy: moving to multi-dimensional data. 
  • Prediction of potential for organ donation after circulatory death in neurocritical patients. 
  • Predictors of Vasopressin Responsiveness in Critically Ill Adults. 
  • Predictors of short-term mortality in patients undergoing percutaneous dilatational tracheostomy. 
  • Prevalence, Risk Factors, and Outcomes of Financial Stress in Survivors of Critical Illness. 
  • Prevention of Critical Care Complications in the Coronary Intensive Care Unit: Protocols, Bundles, and Insights From Intensive Care Studies. 
  • Probiotic administration and the incidence of nosocomial infection in pediatric intensive care: a randomized placebo-controlled trial. 
  • Probiotic and synbiotic therapy in critical illness: a systematic review and meta-analysis. 
  • Proceedings from the Society of Interventional Radiology research consensus panel on critical limb ischemia. 
  • Prognostic accuracy of Acute Physiology and Chronic Health Evaluation II scores in critically ill cancer patients. 
  • Project CAPE: a high-fidelity, in situ simulation program to increase Critical Access Hospital Emergency Department provider comfort with seriously ill pediatric patients. 
  • Protective role of the apolipoprotein E2 allele in age-related disease traits and survival: evidence from the Long Life Family Study. 
  • Protein-energy nutrition in the ICU is the power couple: A hypothesis forming analysis. 
  • Protocolized sedation vs usual care in pediatric patients mechanically ventilated for acute respiratory failure: a randomized clinical trial. 
  • Recognition and Clinical Presentation of Invasive Fungal Disease in Neonates and Children. 
  • Recommendations on the Indications for RBC Transfusion for the Critically Ill Child Receiving Support From Extracorporeal Membrane Oxygenation, Ventricular Assist, and Renal Replacement Therapy Devices From the Pediatric Critical Care Transfusion and Anemia Expertise Initiative. 
  • Redox therapy in neonatal sepsis: reasons, targets, strategy, and agents. 
  • Relationship Between Adverse Tracheal Intubation Associated Events and PICU Outcomes. 
  • Relationship of body mass index to subsequent mortality among seriously ill hospitalized patients. SUPPORT Investigators. The Study to Understand Prognoses and Preferences for Outcome and Risks of Treatments. 
  • Relationship of vitamin D deficiency to clinical outcomes in critically ill patients. 
  • Renal systems biology of patients with systemic inflammatory response syndrome. 
  • Reply: Do We Really Know How to Use High-Frequency Oscillatory Ventilation in Critically Ill Children? 
  • Researching breathlessness in palliative care: consensus statement of the National Cancer Research Institute Palliative Care Breathlessness Subgroup. 
  • Respiratory Viral Coinfections in the PICU: More Is Not Better...But Is It Worse? 
  • Response to "Reassessing the death risk related to probiotics in critically ill patients". 
  • Restoring the Microbiome in Critically Ill Patients: Are Probiotics Our True Friends When We Are Seriously Ill? 
  • Risk Factors for Post-Traumatic Stress Disorder Symptoms in Surrogate Decision-Makers of Patients with Chronic Critical Illness. 
  • Risk factors and impact of major bleeding in critically ill patients receiving heparin thromboprophylaxis. 
  • Role of L-glutamine in critical illness: new insights. 
  • Role of the microbiome, probiotics, and 'dysbiosis therapy' in critical illness. 
  • ST2 Predicts Mortality and Length of Stay in a Critically Ill Noncardiac Intensive Care Unit Population. 
  • Safety and Effectiveness of Retrograde Arterial Access for Endovascular Treatment of Critical Limb Ischemia. 
  • Safety and effectiveness of meropenem in infants with suspected or complicated intra-abdominal infections. 
  • Sedation Management for Critically Ill Children with Pre-Existing Cognitive Impairment. 
  • Sedation and subglottic stenosis in critically ill children. 
  • Sedatives and Analgesics Given to Infants in Neonatal Intensive Care Units at the End of Life. 
  • Setting the vision: applied patient-reported outcomes and smart, connected digital healthcare systems to improve patient-centered outcomes prediction in critical illness. 
  • Should Early Mobilization Be Routine in Mechanically Ventilated Patients? 
  • Should modulation of p50 be a therapeutic target in the critically ill? 
  • Statins and delirium during critical illness: a multicenter, prospective cohort study. 
  • Strict glycemic targets need not be so strict: a more permissive glycemic range for critically ill children. 
  • Supplemental Parenteral Nutrition: Review of the Literature and Current Nutrition Guidelines. 
  • Surveillance for unexplained deaths and critical illnesses due to possibly infectious causes, United States, 1995-1998. 
  • Survival in critical illness is associated with early activation of mitochondrial biogenesis. 
  • Symptomatic event reduction with extended-duration betrixaban in acute medically ill hospitalized patients. 
  • Tailoring nutrition therapy to illness and recovery. 
  • Temperature profile and outcomes of neonates undergoing whole body hypothermia for neonatal hypoxic-ischemic encephalopathy. 
  • The CRIT Study: Anemia and blood transfusion in the critically ill--current clinical practice in the United States. 
  • The Impact of Capping Creatinine Clearance on Achieving Therapeutic Vancomycin Concentrations in Neurocritically Ill Patients with Traumatic Brain Injury. 
  • The SUPPORT prognostic model. Objective estimates of survival for seriously ill hospitalized adults. Study to understand prognoses and preferences for outcomes and risks of treatments. 
  • The Uniformed Services University's Surgical Critical Care Initiative (SC2i): Bringing Precision Medicine to the Critically Ill. 
  • The Voice of Surrogate Decision-Makers. Family Responses to Prognostic Information in Chronic Critical Illness. 
  • The authors reply. 
  • The authors reply. 
  • The authors reply. 
  • The challenge of measuring community values in ways appropriate for setting health care priorities. 
  • The chronically critically ill patient: pediatric considerations. 
  • The effectiveness of right heart catheterization in the initial care of critically ill patients. SUPPORT Investigators. 
  • The epidemiology of chronic critical illness in the United States*. 
  • The evolution of nutrition in critical care: how much, how soon? 
  • The future of critical care nutrition therapy. 
  • The impact of delirium on clinical outcomes in mechanically ventilated surgical and trauma patients. 
  • The number of tracheal intubation attempts matters! A prospective multi-institutional pediatric observational study. 
  • The structure of critical care transfer networks. 
  • The use of vasoactive agents via peripheral intravenous access during transport of critically III infants and children. 
  • Therapeutic Alliance between the Caregivers of Critical Illness Survivors and Intensive Care Unit Clinicians. 
  • Tight glycemic control reduces infection and improves neurological outcome in critically ill neurosurgical and neurological patients. 
  • Timing is everything? Reconciling the results of recent trials in acute kidney injury. 
  • Tools to Promote Shared Decision Making in Serious Illness: A Systematic Review. 
  • Toward Solving the Sedation-Assessment Conundrum: Neurofunction Monitoring. 
  • Transabdominal duplex ultrasonography for bedside inferior vena cava filter placement: examples, technique, and review. 
  • Transfusion in critical care - a UK regional audit of current practice. 
  • Transfusion of fresh frozen plasma in critically ill surgical patients is associated with an increased risk of infection. 
  • Transporting Critically Ill Children-Are We All on the Same Page? 
  • Understanding the continuum of palliative care for patients and their caregivers. 
  • Update in hospital palliative care. 
  • Usability Testing of an Electronic Patient-Reported Outcome System for Survivors of Critical Illness. 
  • Use of daily Acute Physiology and Chronic Health Evaluation (APACHE) II scores to predict individual patient survival rate. 
  • Use of high flow nasal cannula in critically ill infants, children, and adults: a critical review of the literature. 
  • Using Technology to Create a More Humanistic Approach to Integrating Palliative Care into the Intensive Care Unit. 
  • Wait! Wait! I Am Not Dead Yet! 
  • What is the ideal crystalloid? 
  • Winning the war against ICU-acquired weakness: new innovations in nutrition and exercise physiology. 
  • Worry about child health in mothers of hospitalized medically fragile infants. 
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  Keywords of People

  • O'Connor, Christopher Michael, Richard Sean Stack, M.D. / Guidant Foundation Distinguished Professor of Cardiology, Medicine, Clinical Pharmacology
  • Olsen, Maren Karine, Associate Professor of Biostatistics and Bioinformatics, Biostatistics & Bioinformatics
  • Turner, David Ashley, Associate Professor of Pediatrics, Pediatrics, Critical Care Medicine