Genome

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  Subject Areas on Research

  • (Session Introduction) Joint Learning from Multiple Types of Genomic Data 
  • 29 mammalian genomes reveal novel exaptations of mobile elements for likely regulatory functions in the human genome. 
  • A Bayesian hierarchical model to estimate DNA methylation conservation in colorectal tumors. 
  • A Decade of CRISPR-Cas Gnome Editing in C. elegans . 
  • A brave new synthetic world. A report of the first meeting on 'Frontiers in Synthetic Biology', Boston, USA, 1-2 December 2008. 
  • A case study of the reproducibility of transcriptional reporter cell-based RNAi screens in Drosophila. 
  • A chromosome-level reference genome and pangenome for barn swallow population genomics. 
  • A course-based research experience: how benefits change with increased investment in instructional time. 
  • A deletion-generator compound element allows deletion saturation analysis for genomewide phenotypic annotation. 
  • A draft genome sequence of the elusive giant squid, Architeuthis dux. 
  • A genetic linkage map of the laboratory rat, Rattus norvegicus. 
  • A genome end-game: understanding gene function in the nervous system. 
  • A genome-wide RNAi screen reveals multiple regulators of caspase activation. 
  • A genome-wide search for linkage to asthma phenotypes in the genetics of asthma international network families: evidence for a major susceptibility locus on chromosome 2p. 
  • A genome-wide survey of the evolutionarily conserved Wnt pathways in the sea urchin Strongylocentrotus purpuratus. 
  • A genomewide scan for early-onset coronary artery disease in 438 families: the GENECARD Study. 
  • A genomic regulatory network for development. 
  • A haplotype-resolved genome assembly of the Nile rat facilitates exploration of the genetic basis of diabetes. 
  • A high-quality genome and comparison of short- versus long-read transcriptome of the palaearctic duck Aythya fuligula (tufted duck). 
  • A high-quality, long-read genome assembly of the endangered ring-tailed lemur (Lemur catta). 
  • A high-resolution map of human evolutionary constraint using 29 mammals. 
  • A methodology for utilization of predictive genomic signatures in FFPE samples. 
  • A new duck genome reveals conserved and convergently evolved chromosome architectures of birds and mammals. 
  • A new emu genome illuminates the evolution of genome configuration and nuclear architecture of avian chromosomes. 
  • A physical map of the mouse genome. 
  • A recombinational portrait of the Drosophila pseudoobscura genome. 
  • A sampling of methods to study chromosome and genome structure and function. 
  • A sea urchin genome project: sequence scan, virtual map, and additional resources. 
  • A unique role of the DNA fragmentation factor in maintaining genomic stability. 
  • ATAC-ing the mechanisms of renin regulation. 
  • Absence of a simple code: how transcription factors read the genome. 
  • Adaptive Radiation Genomics of Two Ecologically Divergent Hawai'ian Honeycreepers: The 'akiapōlā'au and the Hawai'i 'amakihi. 
  • Advances in targeted genome editing. 
  • Advancing toxicology research using in vivo high throughput toxicology with small fish models. 
  • Alu Insertion Polymorphisms as Evidence for Population Structure in Baboons. 
  • An Arabidopsis thaliana lipoxygenase gene can be induced by pathogens, abscisic acid, and methyl jasmonate. 
  • An SSLP marker-anchored BAC framework map of the mouse genome. 
  • An algorithm for the reconstruction of consensus sequences of ancient segmental duplications and transposon copies in eukaryotic genomes. 
  • An encyclopedia of mouse DNA elements (Mouse ENCODE). 
  • An ensemble model of competitive multi-factor binding of the genome. 
  • An improved germline genome assembly for the sea lamprey Petromyzon marinus illuminates the evolution of germline-specific chromosomes. 
  • Ancient bacterial endosymbionts of insects: Genomes as sources of insight and springboards for inquiry. 
  • Animals in a bacterial world, a new imperative for the life sciences. 
  • Applications of high-throughput RNA interference screens to problems in cell and developmental biology. 
  • Avian Binocularity and Adaptation to Nocturnal Environments: Genomic Insights from a Highly Derived Visual Phenotype. 
  • Avian genomes. A flock of genomes. Introduction. 
  • Avianbase: a community resource for bird genomics. 
  • Balancing selection maintains hyper-divergent haplotypes in Caenorhabditis elegans. 
  • Bayesian genome- and epigenome-wide association studies with gene level dependence. 
  • Bone-associated gene evolution and the origin of flight in birds. 
  • Breed Differences in Dog Cognition Associated with Brain-Expressed Genes and Neurological Functions. 
  • CRISPR Library Screening in Cultured Cardiomyocytes. 
  • CRISPR-Cas9-Guided Genome Engineering in C. elegans. 
  • Caenorhabditis elegans DNA mismatch repair gene msh-2 is required for microsatellite stability and maintenance of genome integrity. 
  • Capturing the primordial Kras mutation initiating urethane carcinogenesis. 
  • Carbon sequestration in Synechococcus Sp.: from molecular machines to hierarchical modeling. 
  • Caspase-3 promotes genetic instability and carcinogenesis. 
  • ChIP-seq guidelines and practices of the ENCODE and modENCODE consortia. 
  • Chromatin and DNA replication. 
  • Chromosomal-Level Genome Assembly of the Sea Urchin Lytechinus variegatus Substantially Improves Functional Genomic Analyses. 
  • Chromosome-Level Reference Genomes for Two Strains of Caenorhabditis briggsae: An Improved Platform for Comparative Genomics. 
  • Comparative RNA sequencing reveals substantial genetic variation in endangered primates. 
  • Comparative embryology without a microscope: using genomic approaches to understand the evolution of development. 
  • Comparative genome sequencing of Drosophila pseudoobscura: chromosomal, gene, and cis-element evolution. 
  • Comparative genomics reveals insights into avian genome evolution and adaptation. 
  • Comparing reference-based RNA-Seq mapping methods for non-human primate data. 
  • Complete genomic screen for disease susceptibility loci in nuclear families. 
  • Complexity reduction in context-dependent DNA substitution models. 
  • Composition and dynamics of the Caenorhabditis elegans early embryonic transcriptome. 
  • Computational analysis of core promoters in the Drosophila genome. 
  • Consequences of recombination rate variation on quantitative trait locus mapping studies. Simulations based on the Drosophila melanogaster genome. 
  • Conservation of dynamic characteristics of transcriptional regulatory elements in periodic biological processes. 
  • Convergent and divergent evolution of genomic imprinting in the marsupial Monodelphis domestica. 
  • Convergent evolution of chicken Z and human X chromosomes by expansion and gene acquisition. 
  • Convergent evolution of chromosomal sex-determining regions in the animal and fungal kingdoms. 
  • Coordinated genome-wide modifications within proximal promoter cis-regulatory elements during vertebrate evolution 
  • Core and region-enriched networks of behaviorally regulated genes and the singing genome. 
  • Cross species genomic analysis identifies a mouse model as undifferentiated pleomorphic sarcoma/malignant fibrous histiocytoma. 
  • DNA-remethylation around a STAT5-binding enhancer in the alphaS1-casein promoter is associated with abrupt shutdown of alphaS1-casein synthesis during acute mastitis. 
  • DNase-seq: a high-resolution technique for mapping active gene regulatory elements across the genome from mammalian cells. 
  • Darwinian genomics and diversity in the tree of life. 
  • De novo PacBio long-read and phased avian genome assemblies correct and add to reference genes generated with intermediate and short reads. 
  • Defining origins of replication in mammalian cells. 
  • Detecting differential copy number variation between groups of samples. 
  • Detection of clinically relevant genetic variants in autism spectrum disorder by whole-genome sequencing. 
  • Developmental roles of pufferfish Hox clusters and genome evolution in ray-fin fish. 
  • Dissection of a quantitative trait locus for PR interval duration identifies Tnni3k as a novel modulator of cardiac conduction. 
  • Drosophila muller f elements maintain a distinct set of genomic properties over 40 million years of evolution. 
  • Dynamic incorporation of multiple in silico functional annotations empowers rare variant association analysis of large whole-genome sequencing studies at scale. 
  • Early low-titer neutralizing antibodies impede HIV-1 replication and select for virus escape. 
  • Earth BioGenome Project: Sequencing life for the future of life. 
  • EchinoDB, an application for comparative transcriptomics of deeply-sampled clades of echinoderms. 
  • Editing the Epigenome: Reshaping the Genomic Landscape. 
  • Editing the Neuronal Genome: a CRISPR View of Chromatin Regulation in Neuronal Development, Function, and Plasticity. 
  • Effects of Space Flight on Mouse Liver versus Kidney: Gene Pathway Analyses. 
  • Effects of glutathione on chromium-induced DNA crosslinking and DNA polymerase arrest. 
  • Effects of inversions on within- and between-species recombination and divergence. 
  • Efficient Genome Editing in Caenorhabditis elegans with a Toolkit of Dual-Marker Selection Cassettes. 
  • Efficient Genome-Wide Sequencing and Low-Coverage Pedigree Analysis from Noninvasively Collected Samples. 
  • Endosymbiont evolution: predictions from theory and surprises from genomes. 
  • Endosymbiosis: lessons in conflict resolution. 
  • Epigenome characterization at single base-pair resolution. 
  • Epigenomics of centromere assembly and function. 
  • Evaluation of the genomic extent of effects of fixed inversion differences on intraspecific variation and interspecific gene flow in Drosophila pseudoobscura and D. persimilis. 
  • Evidence for GC-biased gene conversion as a driver of between-lineage differences in avian base composition. 
  • Evidence for a single loss of mineralized teeth in the common avian ancestor. 
  • Evidence for multiple loci from a genome scan of autism kindreds. 
  • Evolution. CNCing is believing. 
  • Evolutionary and biomedical insights from a marmoset diploid genome assembly. 
  • Evolutionary and ecological functional genomics. 
  • Evolutionary and phylogenetic insights from a nuclear genome sequence of the extinct, giant, "subfossil" koala lemur Megaladapis edwardsi. 
  • Evolutionary genetics and acclimatization in nephrology. 
  • F-Seq: a feature density estimator for high-throughput sequence tags. 
  • False gene and chromosome losses in genome assemblies caused by GC content variation and repeats. 
  • From disease ontology to disease-ontology lite: statistical methods to adapt a general-purpose ontology for the test of gene-ontology associations. 
  • Functional analysis of novel SNPs and mutations in human and mouse genomes. 
  • Functional organization of the genome may shape the species boundary in the house mouse. 
  • GREAT improves functional interpretation of cis-regulatory regions. 
  • GWAS analyzer: integrating genotype, phenotype and public annotation data for genome-wide association study analysis. 
  • Gene conversion and linkage: effects on genome evolution and speciation. 
  • Gene loss, adaptive evolution and the co-evolution of plumage coloration genes with opsins in birds. 
  • Gene-environment regulatory circuits of right ventricular pathology in tetralogy of fallot. 
  • General olfactory sensitivity database (GOSdb): candidate genes and their genomic variations. 
  • Generalized dead-end elimination algorithms make large-scale protein side-chain structure prediction tractable: implications for protein design and structural genomics. 
  • Genetic and genomic evolution of sexual reproduction: echoes from LECA to the fungal kingdom. 
  • Genome accessibility is widely preserved and locally modulated during mitosis. 
  • Genome annotation assessment in Drosophila melanogaster. 
  • Genome editing: the end of the beginning. 
  • Genome evolution in an insect cell: distinct features of an ant-bacterial partnership. 
  • Genome-editing Technologies for Gene and Cell Therapy. 
  • Genome-scale functional genomics identify genes preferentially essential for multiple myeloma cells compared to other neoplasias. 
  • Genome-wide activity-dependent MeCP2 phosphorylation regulates nervous system development and function. 
  • Genome-wide analysis of STAT target genes: elucidating the mechanism of STAT-mediated oncogenesis. 
  • Genome-wide analysis of heat stress-stimulated transposon mobility in the human fungal pathogen Cryptococcus deneoformans. 
  • Genome-wide identification of autosomal genes with allelic imbalance of chromatin state. 
  • Genome-wide identification of calcium-response factor (CaRF) binding sites predicts a role in regulation of neuronal signaling pathways. 
  • Genome-wide identification of regulatory elements in Sertoli cells. 
  • Genome-wide meta-analyses identify multiple loci associated with smoking behavior. 
  • Genome-wide patterns of expression in Drosophila pure species and hybrid males. 
  • Genome-wide prediction of imprinted murine genes. 
  • Genome-wide scan reveals signatures of selection related to pollution adaptation in non-model estuarine Atlantic killifish (Fundulus heteroclitus). 
  • Genomic abnormalities of the murine model of Fabry disease after disease-related perturbation, a systems biology approach. 
  • Genomic and functional variation of human centromeres. 
  • Genomic determination of the glucocorticoid response reveals unexpected mechanisms of gene regulation. 
  • Genomic mismatch scanning: a new approach to genetic linkage mapping. 
  • Genomic prediction of locoregional recurrence after mastectomy in breast cancer. 
  • Genomic predictors of the maximal O₂ uptake response to standardized exercise training programs. 
  • Genomic sequence and expression of a cloned human carbonyl reductase gene with daunorubicin reductase activity. 
  • Genomic signatures of G-protein-coupled receptor expansions reveal functional transitions in the evolution of cephalopod signal transduction. 
  • Genomic signatures of near-extinction and rebirth of the crested ibis and other endangered bird species. 
  • Gfastats: conversion, evaluation and manipulation of genome sequences using assembly graphs. 
  • Globally Relaxed Selection and Local Adaptation in Boechera stricta. 
  • Great ape genetic diversity and population history. 
  • Guidelines for Genome-Scale Analysis of Biological Rhythms. 
  • Haplotype-resolved assembly of diploid genomes without parental data. 
  • Heterochromatic sequences in a Drosophila whole-genome shotgun assembly. 
  • Hi-C scaffolded short- and long-read genome assemblies of the California sea lion are broadly consistent for syntenic inference across 45 million years of evolution. 
  • High-resolution genome-wide in vivo footprinting of diverse transcription factors in human cells. 
  • Human apolipoprotein E2, E3, and E4 isoform-specific transgenic mice: human-like pattern of glial and neuronal immunoreactivity in central nervous system not observed in wild-type mice. 
  • Hybrid de novo genome assembly and centromere characterization of the gray mouse lemur (Microcebus murinus). 
  • Hypertension and albuminuria in chronic kidney disease mapped to a mouse chromosome 11 locus. 
  • Identification of novel mediators of NF-kappaB through genome-wide survey of monocyte adherence-induced genes. 
  • Identification of risk and age-at-onset genes on chromosome 1p in Parkinson disease. 
  • Identification of variants in CNGA3 as cause for achromatopsia by exome sequencing of a single patient. 
  • Identifying branch-specific positive selection throughout the regulatory genome using an appropriate proxy neutral. 
  • Identifying gene regulatory elements by genome-wide recovery of DNase hypersensitive sites. 
  • Impact of Conditioning Intensity and Genomics on Relapse After Allogeneic Transplantation for Patients With Myelodysplastic Syndrome. 
  • Incorporation of a horizontally transferred gene into an operon during cnidarian evolution. 
  • Induction of an immortalized songbird cell line allows for gene characterization and knockout by CRISPR-Cas9. 
  • Induction of internucleosomal DNA fragmentation by carcinogenic chromate: relationship to DNA damage, genotoxicity, and inhibition of macromolecular synthesis. 
  • Infectious pathogen detection arrays: viral detection in cell lines and postmortem brain tissue. 
  • Initial sequencing and comparative analysis of the mouse genome. 
  • Initiation of the Primate Genome Project. 
  • Integrative genomic approaches identify IKBKE as a breast cancer oncogene. 
  • Interpreting the genomic landscape of speciation: a road map for finding barriers to gene flow. 
  • Intraspecific phylogenetic congruence among multiple symbiont genomes. 
  • Intraspecific variation in symbiont genomes: bottlenecks and the aphid-buchnera association. 
  • Intrinsic and cyclin-dependent kinase-dependent control of spindle pole body duplication in budding yeast. 
  • Inversions shape the divergence of Drosophila pseudoobscura and Drosophila persimilis on multiple timescales. 
  • Jumping at the chance for precise DNA integration. 
  • Less is more: compact genomes pay dividends. 
  • Lichens. 
  • Lineage-specific expansions provide genomic complexity among sea urchin GTPases. 
  • Little qualitative RNA misexpression in sterile male F1 hybrids of Drosophila pseudoobscura and D. persimilis. 
  • Loss of a histone deacetylase dramatically alters the genomic distribution of Spo11p-catalyzed DNA breaks in Saccharomyces cerevisiae. 
  • Low frequency of paleoviral infiltration across the avian phylogeny. 
  • Mechanistic insights into cancer cell killing through interaction of phosphodiesterase 3A and schlafen family member 12. 
  • Mechanotransduction Mechanisms for Intraventricular Diastolic Vortex Forces and Myocardial Deformations: Part 2. 
  • Merfin: improved variant filtering, assembly evaluation and polishing via k-mer validation. 
  • Metagenomic and small-subunit rRNA analyses reveal the genetic diversity of bacteria, archaea, fungi, and viruses in soil. 
  • Mimulus is an emerging model system for the integration of ecological and genomic studies 
  • Mismatch repair proteins and mitotic genome stability. 
  • Mitochondrial DNA polymorphism A4917G is independently associated with age-related macular degeneration. 
  • Modelling the effects of age-related mtDNA mutation accumulation; complex I deficiency, superoxide and cell death. 
  • Molecular biologist's guide to proteomics. 
  • Molecular genetics of successful smoking cessation: convergent genome-wide association study results. 
  • Morphological and genomic shifts in mole-rat 'queens' increase fecundity but reduce skeletal integrity. 
  • Motif composition, conservation and condition-specificity of single and alternative transcription start sites in the Drosophila genome. 
  • Multiplex CRISPR/Cas9-based genome editing for correction of dystrophin mutations that cause Duchenne muscular dystrophy. 
  • Multiplex CRISPR/Cas9-based genome engineering from a single lentiviral vector. 
  • Murine noroviruses comprising a single genogroup exhibit biological diversity despite limited sequence divergence. 
  • NAFLD is associated with methylation shifts with relevance for the expression of genes involved in lipoprotein particle composition. 
  • Nonconsensus Protein Binding to Repetitive DNA Sequence Elements Significantly Affects Eukaryotic Genomes. 
  • Novel Insights into Chromosome Evolution in Birds, Archosaurs, and Reptiles. 
  • Nucleosome Turnover Regulates Histone Methylation Patterns over the Genome. 
  • Olfactory Receptor Subgenomes Linked with Broad Ecological Adaptations in Sauropsida. 
  • On a Special Collection in MMBR on Sex in Fungi: Molecular Mechanisms and Evolutionary Implications. 
  • Organization and evolution of a gene-rich region of the mouse genome: a 12.7-Mb region deleted in the Del(13)Svea36H mouse. 
  • Organizing mRNA export. 
  • OrthoClusterDB: an online platform for synteny blocks. 
  • Overlapping high-resolution copy number alterations in cancer genomes identified putative cancer genes in hepatocellular carcinoma. 
  • Palo: spatially aware color palette optimization for single-cell and spatial data. 
  • Parrot Genomes and the Evolution of Heightened Longevity and Cognition. 
  • Participant choices for return of genomic results in the eMERGE Network. 
  • Pedigree-based and phylogenetic methods support surprising patterns of mutation rate and spectrum in the gray mouse lemur. 
  • Perspectives from the Avian Phylogenomics Project: Questions that Can Be Answered with Sequencing All Genomes of a Vertebrate Class. 
  • Phylogenomic analyses data of the avian phylogenomics project. 
  • Platypus and echidna genomes reveal mammalian biology and evolution. 
  • Polyploidy: A Biological Force From Cells to Ecosystems. 
  • Population genomics reveal recent speciation and rapid evolutionary adaptation in polar bears. 
  • Predicting Alzheimer's Disease Using Combined Imaging-Whole Genome SNP Data. 
  • Predicting cell-type-specific gene expression from regions of open chromatin. 
  • Preface. 
  • Progressive Cactus is a multiple-genome aligner for the thousand-genome era. 
  • Prospective estimation of recombination signal efficiency and identification of functional cryptic signals in the genome by statistical modeling. 
  • PseudoBase: a genomic visualization and exploration resource for the Drosophila pseudoobscura subgroup. 
  • Pulling the genome in opposite directions to dissect gene networks. 
  • RTK and TGF-beta signaling pathways genes in the sea urchin genome. 
  • RUNX1 maintains the identity of the fetal ovary through an interplay with FOXL2. 
  • Radiation-induced genomic instability: radiation quality and dose response. 
  • Rapid behavioral and genomic responses to social opportunity. 
  • Recent advances in genome editing and creation of genetically modified pigs. 
  • Recombination rate variation in closely related species. 
  • Recombination-Aware Phylogenomics Reveals the Structured Genomic Landscape of Hybridizing Cat Species. 
  • Recombining without Hotspots: A Comprehensive Evolutionary Portrait of Recombination in Two Closely Related Species of Drosophila. 
  • Reference genome and demographic history of the most endangered marine mammal, the vaquita. 
  • Regulatory gene networks and the properties of the developmental process. 
  • Replicated Landscape Genomics Identifies Evidence of Local Adaptation to Urbanization in Wood Frogs. 
  • Response to Comment on "Whole-genome analyses resolve early branches in the tree of life of modern birds". 
  • Returning integrated genomic risk and clinical recommendations: The eMERGE study. 
  • Revising messages traveling along the cellular information superhighway. 
  • Ribonucleoprotein infrastructure regulating the flow of genetic information between the genome and the proteome. 
  • Saving the Patent Law from Itself: Informal Remarks Concerning the Systemic Problems Afflicting Developed Intellectual Property Regimes 
  • Selection against admixture and gene regulatory divergence in a long-term primate field study. 
  • Sequencing studies in human genetics: design and interpretation. 
  • Sequencing three crocodilian genomes to illuminate the evolution of archosaurs and amniotes. 
  • Serial analysis of gene expression (SAGE) in normal human trabecular meshwork. 
  • Shrinkage estimation for robust and efficient screening of single-SNP association from case-control genome-wide association studies. 
  • Site frequency spectra from genomic SNP surveys. 
  • Six reference-quality genomes reveal evolution of bat adaptations. 
  • Spatial organization of the mammalian genome surveillance machinery in response to DNA strand breaks. 
  • Stability selection for regression-based models of transcription factor-DNA binding specificity. 
  • Statistical Viewer: a tool to upload and integrate linkage and association data as plots displayed within the Ensembl genome browser. 
  • Stochastic segment models of eukaryotic promoter regions. 
  • The BLUEPRINT Data Analysis Portal. 
  • The DNA methylation landscape of advanced prostate cancer. 
  • The Genome 10K Project: a way forward. 
  • The NIEHS TaRGET II Consortium and environmental epigenomics. 
  • The Nuclear Pore Complex in Cell Type-Specific Chromatin Structure and Gene Regulation. 
  • The Role of EBV-Induced Hypermethylation in Gastric Cancer Tumorigenesis. 
  • The challenge and promise of estimating the de novo mutation rate from whole-genome comparisons among closely related individuals. 
  • The contribution of admixture to primate evolution. 
  • The correlation of copy number variations with longevity in a genome-wide association study of Han Chinese. 
  • The eMERGE Network: a consortium of biorepositories linked to electronic medical records data for conducting genomic studies. 
  • The effects of nucleotide substitution model assumptions on estimates of nonparametric bootstrap support. 
  • The era of reference genomes in conservation genomics. 
  • The evolutionary significance of cis-regulatory mutations. 
  • The expanding implications of polyploidy. 
  • The forkhead transcription factor FoxI1 remains bound to condensed mitotic chromosomes and stably remodels chromatin structure. 
  • The genome of a songbird. 
  • The genome of the green anole lizard and a comparative analysis with birds and mammals. 
  • The genome of the sea urchin Stongylocentrotus purpuratus 
  • The genomic consequences of adaptive divergence and reproductive isolation between species of manakins. 
  • The genomic underpinnings of apoptosis in Strongylocentrotus purpuratus. 
  • The hard clam genome reveals massive expansion and diversification of inhibitors of apoptosis in Bivalvia. 
  • The histone modification pattern of active genes revealed through genome-wide chromatin analysis of a higher eukaryote. 
  • The invertebrate deuterostomes: an introduction to their phylogeny, reproduction, development, and genomics. 
  • The people behind the papers - Yingxi Cao, Ken Poss and Jingli Cao. 
  • The small subunit of the mammalian mitochondrial ribosome. Identification of the full complement of ribosomal proteins present. 
  • The tardigrade Hypsibius dujardini, a new model for studying the evolution of development. 
  • The western painted turtle genome, a model for the evolution of extreme physiological adaptations in a slowly evolving lineage. 
  • Three crocodilian genomes reveal ancestral patterns of evolution among archosaurs. 
  • Three periods of regulatory innovation during vertebrate evolution. 
  • Truncating BRCA1 mutations are uncommon in a cohort of hereditary prostate cancer families with evidence of linkage to 17q markers. 
  • Tumor necrosis factor-alpha and tumor growth factor-beta1 genotype: partial association with intragraft gene expression in two cases of long-term peripheral tolerance to a kidney transplant. 
  • Two types of recombination hotspots in bacteriophage T4: one requires DNA damage and a replication origin and the other does not. 
  • Uncovering the HARbingers of human brain evolution. 
  • Unlocking the secrets of the genome. 
  • Using Phylogenomic Data to Explore the Effects of Relaxed Clocks and Calibration Strategies on Divergence Time Estimation: Primates as a Test Case. 
  • Visual annotation of the gene database. 
  • Whole genome analysis: experimental access to all genome sequenced segments through larger-scale efficient oligonucleotide synthesis and PCR. 
  • Whole genome expression profiling of normal human fetal and adult ocular tissues. 
  • Whole-Genome Identification, Phylogeny, and Evolution of the Cytochrome P450 Family 2 (CYP2) Subfamilies in Birds. 
  • Whole-genome analyses resolve early branches in the tree of life of modern birds. 
  • Why sequence all eukaryotes? 
  • Widespread false gene gains caused by duplication errors in genome assemblies. 
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  Keywords of People

  • Ferreira, Paulo Alexandre, Associate Professor in Ophthalmology, Pathology
  • Fox, Donald T, Associate Professor of Pharmacology & Cancer Biology, Duke Science & Society
  • Gordan, Raluca Mihaela, Associate Professor in Biostatistics & Bioinformatics, Computer Science
  • Hartemink, Alexander J., Professor in the Department of Computer Science, Biology
  • Liu, Yutao, Adjunct Assistant Professor in the Department of Medicine, Medicine, Medical Genetics
  • Pitt, Geoffrey Stuart, Adjunct Professor in the Department of Medicine, Medicine, Cardiology
  • Reddy, Timothy E, Associate Professor of Biostatistics & Bioinformatics,, Molecular Genetics and Microbiology
  • Sullivan, Beth Ann, Professor of Molecular Genetics and Microbiology, Duke Science & Society
  • Wray, Gregory Allan, Professor of Biology, Evolutionary Anthropology