Genome, Bacterial

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  Subject Areas on Research

  • 50 million years of genomic stasis in endosymbiotic bacteria. 
  • A Bayesian network approach to operon prediction. 
  • A closely-related clade of globally distributed bloom-forming cyanobacteria within the Nostocales. 
  • A genomic survey of positive selection in Burkholderia pseudomallei provides insights into the evolution of accidental virulence. 
  • A probabilistic learning approach to whole-genome operon prediction. 
  • A recently active miniature inverted-repeat transposable element, Chunjie, inserted into an operon without disturbing the operon structure in Geobacter uraniireducens Rf4. 
  • Alternate paradigm for intrinsic transcription termination in eubacteria. 
  • Annual community patterns are driven by seasonal switching between closely related marine bacteria. 
  • Antagonism between Staphylococcus epidermidis and Propionibacterium acnes and its genomic basis. 
  • Characterization of the variable-number tandem repeats in vrrA from different Bacillus anthracis isolates. 
  • Co-orientation of replication and transcription preserves genome integrity. 
  • Comparative genomics of Mortierella elongata and its bacterial endosymbiont Mycoavidus cysteinexigens. 
  • Conserved economics of transcription termination in eubacteria. 
  • Copy number variation contributes to cryptic genetic variation in outbreak lineages of Cryptococcus gattii from the North American Pacific Northwest. 
  • Cospeciation of gut microbiota with hominids. 
  • De novo assembly using low-coverage short read sequence data from the rice pathogen Pseudomonas syringae pv. oryzae. 
  • Decoupling of genome size and sequence divergence in a symbiotic bacterium. 
  • Development of pooled suppression subtractive hybridization to analyze the pangenome of Staphylococcus aureus. 
  • Ecology drives a global network of gene exchange connecting the human microbiome. 
  • Endosymbiont evolution: predictions from theory and surprises from genomes. 
  • Endosymbiont gene functions impaired and rescued by polymerase infidelity at poly(A) tracts. 
  • Endosymbiosis: the evil within. 
  • Engineering of obligate intracellular bacteria: progress, challenges and paradigms. 
  • Fine-scale phylogenetic architecture of a complex bacterial community. 
  • Flavin-dependent thymidylate synthase ThyX activity: implications for the folate cycle in bacteria. 
  • For better or worse: genomic consequences of intracellular mutualism and parasitism. 
  • Forward genetic approaches in Chlamydia trachomatis. 
  • GOBASE--a database of organelle and bacterial genome information. 
  • Genetic and Molecular Basis of Kingella kingae Encapsulation. 
  • Genetic engineering: Chemical control for CRISPR editing. 
  • Genome divergence in two Prochlorococcus ecotypes reflects oceanic niche differentiation. 
  • Genome evolution in bacterial endosymbionts of insects. 
  • Genome organization and three kinds of heritable changes: general description and stochastic factors (a review). 
  • Genome sequence of Blochmannia pennsylvanicus indicates parallel evolutionary trends among bacterial mutualists of insects. 
  • Genome variation in Cryptococcus gattii, an emerging pathogen of immunocompetent hosts. 
  • Genome-Wide Assessment of Outer Membrane Vesicle Production in Escherichia coli. 
  • Genome-scale analysis of anti-metabolite directed strain engineering. 
  • Genomes and gene expression across light and productivity gradients in eastern subtropical Pacific microbial communities. 
  • Genomic Analysis of Multidrug-Resistant Escherichia coli from North Carolina Community Hospitals: Ongoing Circulation of CTX-M-Producing ST131-H30Rx and ST131-H30R1 Strains. 
  • Genomic acquisition of a capsular polysaccharide virulence cluster by non-pathogenic Burkholderia isolates. 
  • Genotypic diversity within a natural coastal bacterioplankton population. 
  • Identification of a chloroform-soluble membrane miniprotein in Escherichia coli and its homolog in Salmonella typhimurium. 
  • Immunostimulatory properties of genomic DNA from different bacterial species. 
  • Improving indel detection specificity of the Ion Torrent PGM benchtop sequencer. 
  • In it for the long haul: evolutionary consequences of persistent endosymbiosis. 
  • Insights and inferences about integron evolution from genomic data. 
  • Integrating chemical mutagenesis and whole-genome sequencing as a platform for forward and reverse genetic analysis of Chlamydia. 
  • Isolation and characterization of a novel Helicobacter species, Helicobacter jaachi sp. nov., from common marmosets (Callithrix jaachus). 
  • Looking for Darwin's footprints in the microbial world. 
  • MUST: a system for identification of miniature inverted-repeat transposable elements and applications to Anabaena variabilis and Haloquadratum walsbyi. 
  • Mismatch repair, genetic stability, and cancer. 
  • Molecular Genetic Analysis of Chlamydia Species. 
  • Molecular characterization of an Escherichia coli clinical isolate that produces both metallo-beta-lactamase VIM-2 and extended-spectrum beta-lactamase GES-7: identification of the In8 integron carrying the blaVIM-2 gene. 
  • Mutation exposed: a neutral explanation for extreme base composition of an endosymbiont genome. 
  • Parallel mapping of genotypes to phenotypes contributing to overall biological fitness. 
  • Phylogenetic, genomic, and biogeographic characterization of a novel and ubiquitous marine invertebrate-associated Rickettsiales parasite, Candidatus Aquarickettsia rohweri, gen. nov., sp. nov. 
  • Polyphasic characterization of four soil-derived phenanthrene-degrading Acidovorax strains and proposal of Acidovorax carolinensis sp. nov. 
  • Prevalence and distribution of the hmw and hia genes and the HMW and Hia adhesins among genetically diverse strains of nontypeable Haemophilus influenzae. 
  • Prevalence of transcription promoters within archaeal operons and coding sequences. 
  • Properties of overlapping genes are conserved across microbial genomes. 
  • Prophage Hunter: an integrative hunting tool for active prophages. 
  • Purifying selection, sequence composition, and context-specific indel mutations shape intraspecific variation in a bacterial endosymbiont. 
  • Reduced selective constraint in endosymbionts: elevation in radical amino acid replacements occurs genome-wide. 
  • Relaxed natural selection alone does not permit transposable element expansion within 4,000 generations in Escherichia coli. 
  • Replication of the Escherichia coli chromosome in RNase HI-deficient cells: multiple initiation regions and fork dynamics. 
  • Small genome of Candidatus Blochmannia, the bacterial endosymbiont of Camponotus, implies irreversible specialization to an intracellular lifestyle. 
  • Strategies of genomic integration within insect-bacterial mutualisms. 
  • Surveillance of carbapenem-resistant Klebsiella pneumoniae: tracking molecular epidemiology and outcomes through a regional network. 
  • The Chlamydia trachomatis Protease CPAF Contains a Cryptic PDZ-Like Domain with Similarity to Human Cell Polarity and Tight Junction PDZ-Containing Proteins. 
  • The MetJ regulon in gammaproteobacteria determined by comparative genomics methods. 
  • The core and accessory genomes of Burkholderia pseudomallei: implications for human melioidosis. 
  • Transfer of photosynthesis genes to and from Prochlorococcus viruses. 
  • Whole genome re-sequencing to identify suppressor mutations of mutant and foreign Escherichia coli FtsZ. 
  • Whole genome sequencing identifies circulating Beijing-lineage Mycobacterium tuberculosis strains in Guatemala and an associated urban outbreak. 
  • Widespread recombination throughout Wolbachia genomes. 
  • Xanthusbase: adapting wikipedia principles to a model organism database. 
  • eSGA: E. coli synthetic genetic array analysis.