Immunocompromised Host

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  Subject Areas on Research

  • A cord blood transplant recipient with Mycobacterium mucogenicum central venous catheter infection after infusion of tap water. 
  • A transcriptional signature accurately identifies Aspergillus Infection across healthy and immunosuppressed states. 
  • ACR Appropriateness Criteria(®) Aggressive Nonmelanomatous Skin Cancer of the Head and Neck. 
  • ACR Appropriateness Criteria® Acute Respiratory Illness in Immunocompromised Patients. 
  • Acquired Pelger-Huët anomaly in association with concomitant tacrolimus and mycophenolate mofetil in a liver transplant patient: a case report and review of the literature. 
  • Alemtuzumab induction and triple maintenance immunotherapy in kidney transplantation from donors after cardiac death. 
  • An approach to fulminant invasive fungal rhinosinusitis in the immunocompromised host. 
  • An atypical case of fatal zygomycosis: simultaneous cutaneous and laryngeal infection in a patient with a non-neutropenic solid prostatic tumor. 
  • Annual direct and indirect health care costs of chronic idiopathic urticaria: a cost analysis of 50 nonimmunosuppressed patients. 
  • Antibiotic resistance in the patient with cancer: Escalating challenges and paths forward. 
  • Antifungal agents and therapy for infants and children with invasive fungal infections: a pharmacological perspective. 
  • Antifungal prophylaxis: to prevent or not. 
  • Antimicrobial resistance: resistance to antifungal agents: mechanisms and clinical impact. 
  • Application of stem cell transplantation in autoimmune diseases. 
  • Aspergillus infections in transplant and non-transplant surgical patients. 
  • Association of leukocyte-depleted blood transfusions with infectious complications after cardiac surgery. 
  • Avascular necrosis following bone marrow transplantation: a case-control study. 
  • Bacillus cereus necrotizing cellulitis mimicking clostridial myonecrosis: case report and review of the literature. 
  • Bacterial etiology of community-acquired pneumonia in immunocompetent hospitalized patients and appropriateness of empirical treatment recommendations: an international point-prevalence study. 
  • Bilateral nodular pulmonary infiltrates in an immunocompromised host. 
  • Blastomycosis. 
  • Breakthrough invasive fungal infections: Who is at risk? 
  • Broad spectrum triazoles for invasive mould infections in adults: Which drug and when? 
  • CD3-positive diffuse large B-cell lymphoma relapses as CD3-negative large B-cell lymphoma: Loss of aberrant antigen expression in B-cell lymphoma after chemotherapy. 
  • CD62L- memory T cells enhance T-cell regeneration after allogeneic stem cell transplantation by eliminating host resistance in mice. 
  • COVID-19 Among Liver Transplant Recipients. 
  • COVID-19 in solid organ transplant recipients: A systematic review and meta-analysis of current literature. 
  • Cancer Therapy-associated Lymphoproliferative Disorders: An Under-recognized Type of Immunodeficiency-associated Lymphoproliferative Disorder. 
  • Capnocytophagia canimorsus sepsis in an asplenic heart transplant candidate with a left ventricular assist system. 
  • Chronic coinfections in patients diagnosed with chronic lyme disease: a systematic review. 
  • Chronic phototoxicity and aggressive squamous cell carcinoma of the skin in children and adults during treatment with voriconazole. 
  • Classical Hodgkin lymphoma arising in the setting of iatrogenic immunodeficiency: a clinicopathologic study of 10 cases. 
  • Clinical Course of Preseptal and Orbital Cellulitis in 50 Immunocompromised Patients with Cancer. 
  • Clinical problem-solving. Index of suspicion. 
  • Clostridium septicum abscess in hepatic metastases: successful medical management. 
  • Cluster of oseltamivir-resistant 2009 pandemic influenza A (H1N1) virus infections on a hospital ward among immunocompromised patients--North Carolina, 2009. 
  • Combination antifungal therapy: what can and should we expect? 
  • Comparative Effectiveness of Moderna, Pfizer-BioNTech, and Janssen (Johnson & Johnson) Vaccines in Preventing COVID-19 Hospitalizations Among Adults Without Immunocompromising Conditions - United States, March-August 2021. 
  • Comparison of pharmacokinetics and safety of voriconazole intravenous-to-oral switch in immunocompromised adolescents and healthy adults. 
  • Comparison of pharmacokinetics and safety of voriconazole intravenous-to-oral switch in immunocompromised children and healthy adults. 
  • Concurrent classical Hodgkin lymphoma and plasmablastic lymphoma in a patient with chronic lymphocytic leukemia/small lymphocytic lymphoma treated with fludarabine: a dimorphic presentation of iatrogenic immunodeficiency-associated lymphoproliferative disorder with evidence suggestive of multiclonal transformability of B cells by Epstein-Barr virus. 
  • Congenital vulnerability of cutaneous segments arising from skin mosaicism: A genetic basis for locus minoris resistentiae. 
  • Cryptococcosis after solid organ transplantation. 
  • Cryptococcus deuterogattii VGIIa Infection Associated with Travel to the Pacific Northwest Outbreak Region in an Anti-Granulocyte-Macrophage Colony-Stimulating Factor Autoantibody-Positive Patient in the United States. 
  • Cryptococcus gattii Species Complex as an Opportunistic Pathogen: Underlying Medical Conditions Associated with the Infection. 
  • Cryptococcus gattii: an emerging fungal pathogen infecting humans and animals. 
  • Current practices for treatment of respiratory syncytial virus and other non-influenza respiratory viruses in high-risk patient populations: a survey of institutions in the Midwestern Respiratory Virus Collaborative. 
  • Cutaneous acquired toxoplasmosis in a child: a case report and review of the literature. 
  • Cutaneous infection by Mycobacterium haemophilum and kansasii in an IgA-deficient man. 
  • Cutaneous squamous cell carcinoma and human papillomavirus: is there an association? 
  • Cytomegalovirus encephalomyelitis: MR imaging findings documenting response to ganciclovir therapy. 
  • Cytomegalovirus ventriculoencephalitis in a bone marrow transplant recipient receiving antiviral maintenance: clinical and molecular evidence of drug resistance. 
  • DAS181 Treatment of Severe Lower Respiratory Tract Parainfluenza Virus Infection in Immunocompromised Patients: A Phase 2 Randomized, Placebo-Controlled Study. 
  • Delay of CMV infection in high-risk CMV mismatch lung transplant recipients due to prophylaxis with oral ganciclovir. 
  • Design of aerosolized amphotericin b formulations for prophylaxis trials among lung transplant recipients. 
  • Diagnosis of fungal infection: new technologies for the mycology laboratory. 
  • Direct-Acting Antivirals and Organ Transplantation: Is There Anything We Can't Do? 
  • Disruption of a nonribosomal peptide synthetase in Aspergillus fumigatus eliminates gliotoxin production. 
  • Disseminated Candida tropicalis in a patient with chronic mucocutaneous candidiasis. 
  • Disseminated infection with rapidly growing mycobacteria. 
  • Duration of voriconazole exposure: an independent risk factor for skin cancer after lung transplantation. 
  • Early acute lung injury: criteria for identifying lung injury prior to the need for positive pressure ventilation*. 
  • Editorial: Infections of the immunocompromised host: a musing on the changing times. 
  • Effect of Recombinant Zoster Vaccine on Incidence of Herpes Zoster After Autologous Stem Cell Transplantation: A Randomized Clinical Trial. 
  • Effect of the laccase gene CNLAC1, on virulence of Cryptococcus neoformans. 
  • Effectiveness of a Third Dose of Pfizer-BioNTech and Moderna Vaccines in Preventing COVID-19 Hospitalization Among Immunocompetent and Immunocompromised Adults - United States, August-December 2021. 
  • Effects of primary and recurrent sacral chordoma on the motor and nociceptive function of hindlimbs in rats: an orthotopic spine model. 
  • Emergence of resistance to clarithromycin during treatment of disseminated cutaneous Mycobacterium chelonae infection: case report and literature review. 
  • Emergence of the Molds Other than Aspergillus in Immunocompromised Patients. 
  • Emerging Issues in Antifungal Resistance. 
  • Endemic Fungal Infection Recommendations for Solid-Organ Transplant Recipients and Donors. 
  • Enterovirus causes rapidly progressive dementia in a 28-year-old immunosuppressed woman. 
  • Epstein-Barr virus-associated smooth muscle tumor involving the spine of an HIV-infected patient: Case report and review of the literature. 
  • Epstein-Barr virus-associated smooth muscle tumors are distinctive mesenchymal tumors reflecting multiple infection events: a clinicopathologic and molecular analysis of 29 tumors from 19 patients. 
  • Esophageal infections: an update. 
  • Evaluation and management of fungal infections in immunocompromised patients. 
  • Expanding the Spectrum of EBV-positive Marginal Zone Lymphomas: A Lesion Associated With Diverse Immunodeficiency Settings. 
  • Experimental Models of Short Courses of Liposomal Amphotericin B for Induction Therapy for Cryptococcal Meningitis. 
  • Extent of surgical intervention in primary soft-tissue aspergillosis. 
  • Extra-intestinal Hodgkin's lymphoma in a Crohn's disease patient on long-term azathioprine and infliximab therapy. 
  • Extrahippocampal involvement in human herpesvirus 6 encephalitis depicted at MR imaging. 
  • Fatal SV40-associated pneumonia and nephropathy following renal allotransplantation in rhesus macaque. 
  • Fatal Scopulariopsis brevicaulis infection in a paediatric stem-cell transplant patient treated with voriconazole and caspofungin and a review of Scopulariopsis infections in immunocompromised patients. 
  • Fatal disseminated adenovirus infections in immunocompromised patients. 
  • Fulminant hepatic failure due to disseminated adenovirus infection in a patient with chronic lymphocytic leukemia. 
  • Fungal infections in transplant and oncology patients. 
  • Fungi that Infect Humans. 
  • Genetic analysis of intracranial tumors in a murine model of glioma demonstrate a shift in gene expression in response to host immunity. 
  • Global guideline for the diagnosis and management of rare yeast infections: an initiative of the ECMM in cooperation with ISHAM and ASM. 
  • Gram-negative bacteremia upon hospital admission: when should Pseudomonas aeruginosa be suspected? 
  • Guidance on Imaging for Invasive Pulmonary Aspergillosis and Mucormycosis: From the Imaging Working Group for the Revision and Update of the Consensus Definitions of Fungal Disease from the EORTC/MSGERC. 
  • Guidelines for Cervical Cancer Screening in Immunosuppressed Women Without HIV Infection. 
  • Guidelines for assessing immunocompetency in clinical trials for autoimmune diseases. 
  • Guidelines for immunizations in patients with inflammatory bowel disease. 
  • Healthcare associated diarrhea, not Clostridioides difficile. 
  • Herpes Zoster Vaccination: Controversies and Common Clinical Questions. 
  • Herpes zoster in immunocompromised patients: incidence, timing, and risk factors. 
  • Histopathologic assessment of cultured human thymus. 
  • Histoplasmosis after solid organ transplant. 
  • Host-Based Diagnostics for Acute Respiratory Infections. 
  • Human parainfluenza virus giant cell pneumonia following cord blood transplant associated with pulmonary alveolar proteinosis. 
  • Hyperexpansion of Functional Viral-Specific CD8+ T Cells in Lymphopenia-Associated MCMV Pneumonitis. 
  • Ibrutinib-associated invasive fungal diseases in patients with chronic lymphocytic leukaemia and non-Hodgkin lymphoma: An observational study. 
  • Immune reconstitution syndrome and exacerbation of infections after pregnancy. 
  • Immune reconstitution syndrome associated with opportunistic mycoses. 
  • Immunity to commensal papillomaviruses protects against skin cancer. 
  • Immunocompromised Host Pneumonia: Definitions and Diagnostic Criteria: An Official American Thoracic Society Workshop Report. 
  • Immunological and Pathological Landscape of Dengue Serotypes 1-4 Infections in Immune-Competent Mice. 
  • Immunosuppression related to collagen-vascular disease or its treatment. 
  • Increasing Nocardia Incidence Associated with Bronchiectasis at a Tertiary Care Center. 
  • Infections after the use of alemtuzumab in solid organ transplant recipients: a comparative study. 
  • Infections in the immunosuppressed host. 
  • Invasive Curvularia Infection in Pediatric Patients With Hematologic Malignancy Identified by Fungal Sequencing. 
  • Invasive fungal infections among organ transplant recipients: results of the Transplant-Associated Infection Surveillance Network (TRANSNET). 
  • Invasive fungal infections in neonates: a review. 
  • Isavuconazole treatment for rare fungal diseases and for invasive aspergillosis in patients with renal impairment: Challenges and lessons of the VITAL trial. 
  • Kidney transplant recipients infected by COVID-19: Review of the initial published experience. 
  • Lymphoproliferative disorders: CT findings in immunocompromised children. 
  • Malignancy after solid organ transplantation: an overview. 
  • Management of an Outbreak of Exophiala dermatitidis Bloodstream Infections at an Outpatient Oncology Clinic. 
  • Manifestations and outcomes of nocardia infections: Comparison of immunocompromised and nonimmunocompromised adult patients. 
  • Maternal Immunity and Vaccination Influence Disease Severity in Progeny in a Novel Mast Cell-Deficient Mouse Model of Severe Dengue. 
  • Miliary tuberculosis in a paediatric patient with psoriasis. 
  • Misidentification of Neosartorya pseudofischeri as Aspergillus fumigatus in a lung transplant patient. 
  • Molecular identification of Aspergillus species collected for the Transplant-Associated Infection Surveillance Network. 
  • Mucormycosis Rhinosinusitis at Diagnosis of Acute Lymphoblastic Leukemia: Diagnostics and Management Challenges in a Low-Middle-income Country. 
  • Mucormycosis. 
  • Multicenter, prospective clinical evaluation of respiratory samples from subjects at risk for Pneumocystis jirovecii infection by use of a commercial real-time PCR assay. 
  • Mycobacterial infection in immunocompromised patients. 
  • Mycobacterium avium-intracellulare cellulitis occurring with septic arthritis after joint injection: a case report. 
  • Necrotizing fasciitis caused by Haemophilus influenzae type E in a 17-year-old girl with systemic lupus erythematosus. 
  • Necrotizing myofasciitis: an atypical cause of "acute abdomen" in an immunocompromised child. 
  • New facets of antifungal therapy. 
  • Nocardia infection in lung transplant recipients. 
  • Nocardia infections in the transplanted host. 
  • Noninvasive Oxygenation Strategies in Immunocompromised Patients With Acute Hypoxemic Respiratory Failure: A Pairwise and Network Meta-Analysis of Randomized Controlled Trials. 
  • Nonmelanoma skin cancer in inflammatory bowel disease: a review. 
  • Novel use of a swimming pool biocide in the treatment of a rare fungal mastoiditis. 
  • Opening Aeolus' Bag of Winds: Acute Abdominal Pain in a Severely Immunosuppressed Patient. 
  • Opportunistic fungal pneumonia. 
  • Optic chiasm, optic nerve, and retinal involvement secondary to varicella-zoster virus. 
  • Pandemic (H1N1) 2009 and oseltamivir resistance in hematology/oncology patients. 
  • Pathology of parainfluenza virus infection in patients with congenital immunodeficiency syndromes. 
  • Pediatric antifungal agents. 
  • Perioperative management of special populations: immunocompromised host (cancer, HIV, transplantation). 
  • Persistent Mycobacterium avium infection following nonmyeloablative allogeneic peripheral blood stem cell transplantation for interferon-gamma receptor-1 deficiency. 
  • Persistent and Prolonged Parvovirus B19 Viremia in a Pediatric Patient With Acute Lymphoblastic Leukemia. 
  • Perspectives on Scedosporium species and Lomentospora prolificans in lung transplantation: Results of an international practice survey from ESCMID fungal infection study group and study group for infections in compromised hosts, and European Confederation of Medical Mycology. 
  • Pharmacodynamics of liposomal amphotericin B and flucytosine for cryptococcal meningoencephalitis: safe and effective regimens for immunocompromised patients. 
  • Pharmacokinetics and pharmacodynamics of antifungals in children: clinical implications. 
  • Pharmacokinetics and safety of intravenous voriconazole in children after single- or multiple-dose administration. 
  • Pharmacokinetics of antifungal agents in children. 
  • Pharmacokinetics, safety, and tolerability of voriconazole in immunocompromised children. 
  • Pneumococcal Carriage and Vaccine Coverage in Retirement Community Residents. 
  • Pneumonia due to Fonsecaea pedrosoi and cerebral abscesses due to Emericella nidulans in a bone marrow transplant recipient. 
  • Post-transplant lymphoproliferative disorder associated with immunosuppressive therapy for renal transplantation in rhesus macaques (Macaca mulatta). 
  • Preoperative immune status determines anal condyloma recurrence after surgical excision. 
  • Prevalence and Etiology of Community-acquired Pneumonia in Immunocompromised Patients. 
  • Primary central nervous system posttransplant lymphoproliferative disorders. 
  • Profiling a killer, the development of Cryptococcus neoformans. 
  • Proliferative lupus nephritis and leukocytoclastic vasculitis during treatment with etanercept. 
  • Prospective surveillance for invasive fungal infections in hematopoietic stem cell transplant recipients, 2001-2006: overview of the Transplant-Associated Infection Surveillance Network (TRANSNET) Database. 
  • Pulmonary Embolism in a Young Immunocompetent Adult Infected with Cytomegalovirus. Are Novel Oral Anticoagulants an Efficient Alternative? 
  • Pulmonary cryptococcosis in solid organ transplant recipients: clinical relevance of serum cryptococcal antigen. 
  • Pulmonary mucormycosis: radiologic findings in 32 cases. 
  • Pulmonary nontuberculous mycobacterial infection: radiologic manifestations. 
  • Pyogenic variant of primary cutaneous anaplastic large-cell lymphoma: a lymphoproliferative disorder with a predilection for the immunocompromized and the young. 
  • Rare and emerging fungal pulmonary infections. 
  • Recommendations for live viral and bacterial vaccines in immunodeficient patients and their close contacts. 
  • Recommendations for the management of herpes zoster. 
  • Refractory adenovirus infection after simultaneous kidney-pancreas transplantation: successful treatment with intravenous ribavirin and pooled human intravenous immunoglobulin. 
  • Report of the first case of invasive fungal sinusitis caused by Scopulariopsis acremonium: review of scopulariopsis infections. 
  • Revision and Update of the Consensus Definitions of Invasive Fungal Disease From the European Organization for Research and Treatment of Cancer and the Mycoses Study Group Education and Research Consortium. 
  • Risk factors and mortality in invasive Rasamsonia spp. infection: Analysis of cases in the FungiScope® registry and from the literature. 
  • Risk factors in necrotizing fasciitis: a case involving Cryptococcus neoformans. 
  • SARS-CoV-2 Variants in Patients with Immunosuppression. 
  • Safety and efficacy of CMX001 as salvage therapy for severe adenovirus infections in immunocompromised patients. 
  • Safety and efficacy of recombinant and live herpes zoster vaccines for prevention in at-risk adults with chronic diseases and immunocompromising conditions. 
  • Scedosporium species infections and treatments. 
  • Significance of Clostridium tertium bacteremia in neutropenic and nonneutropenic patients: review of 32 cases. 
  • Small intestinal histoplasmosis: successful treatment with itraconazole in an immunocompetent host. 
  • Soft-tissue fungal infections: surgical management of 12 immunocompromised patients. 
  • Staphylococcus aureus bacteremia in patients with neutropenia. 
  • Strategies for the prevention of infection after solid organ transplantation. 
  • Successful extracorporeal membrane oxygenation for respiratory failure in an infant with DiGeorge anomaly, following thymus transplantation. 
  • Successful management of a simultaneous Aspergillus fumigatus and Absidia corymbifera invasive fungal infection. 
  • Successful treatment of disseminated BCG in a patient with severe combined immunodeficiency. 
  • Successful use of amphotericin B lipid complex in the treatment of cryptococcosis. 
  • Survivorship, Version 2.2018, NCCN Clinical Practice Guidelines in Oncology. 
  • The (1,3){beta}-D-glucan test as an aid to early diagnosis of invasive fungal infections following lung transplantation. 
  • The Preuss Foundation Seminar on vaccine therapy for malignant primary brain tumors. February 15-17, 1998, La Jolla, Calif. 
  • The Role of Adjunctive Therapies in the Management of Invasive Sino-Orbital Infection. 
  • The current treatment landscape: other fungal diseases (cryptococcosis, fusariosis and mucormycosis). 
  • The gene encoding phosphoribosylaminoimidazole carboxylase (ADE2) is essential for growth of Cryptococcus neoformans in cerebrospinal fluid. 
  • The impact of the host on fungal infections. 
  • The new fungal opportunists are coming. 
  • The spectrum of fungi that infects humans. 
  • The varied manifestations of disseminated gonococcal infection. 
  • Treatment of non-Aspergillus moulds in immunocompromised patients, with amphotericin B lipid complex. 
  • Trichodysplasia spinulosa--a newly described folliculocentric viral infection in an immunocompromised host. 
  • Type of Organ Transplanted Impacts the Risk and Presentation of Cutaneous Squamous Cell Carcinoma in Transplant Recipients. 
  • Universal Mask Usage for Reduction of Respiratory Viral Infections After Stem Cell Transplant: A Prospective Trial. 
  • Updates on Merkel Cell Carcinoma. 
  • Use of Letermovir for Salvage Therapy for Resistant Cytomegalovirus in a Pediatric Hematopoietic Stem Cell Transplant Recipient. 
  • Utility of fiber-optic bronchoscopy in pulmonary infections among abdominal solid-organ transplant patients: A comprehensive review. 
  • Validation of a Host Gene Expression Test for Bacterial/Viral Discrimination in Immunocompromised Hosts. 
  • Varicella zoster immune globulin (VARIZIG) administration up to 10 days after varicella exposure in pregnant women, immunocompromised participants, and infants: Varicella outcomes and safety results from a large, open-label, expanded-access program. 
  • West Nile virus-associated encephalitis in recipients of renal and pancreas transplants: case series and literature review. 
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  Keywords of People

  • Buckley, Rebecca Hatcher, James Buren Sidbury Distinguished Professor Emeritus of Pediatrics, in the School of Medicine, Pediatrics, Allergy and Immunology
  • Cohen-Wolkowiez, Michael, Kiser-Arena Distinguished Professor, Pediatrics, Infectious Diseases
  • Murdoch, David Martin, Associate Professor of Medicine, Medicine, Pulmonary, Allergy, and Critical Care Medicine
  • Patel, Uptal Dinesh, Adjunct Professor in the Department of Medicine, Medicine, Nephrology
  • Patz Jr., Edward F., James and Alice Chen Distinguished Professor of Radiology, Pathology
  • Sampson, John Howard, Robert H., M.D. and Gloria Wilkins Professor of Neurosurgery, in the School of Medicine, Biomedical Engineering
  • Schanberg, Laura Eve, Professor of Pediatrics, Pediatrics, Rheumatology
  • Schwartz, Ilan, Associate Professor of Medicine, Medicine, Infectious Diseases