Neostriatum

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  Subject Areas on Research

  • A rodent model of spontaneous stereotypy: initial characterization of developmental, environmental, and neurobiological factors. 
  • A wireless multi-channel recording system for freely behaving mice and rats. 
  • Altered striatal functional connectivity in subjects with an at-risk mental state for psychosis. 
  • Androgens and isolation from adult tutors differentially affect the development of songbird neurons critical to vocal plasticity. 
  • Apolipoprotein E deficiency worsens outcome from global cerebral ischemia in the mouse. 
  • Blunted striatal response to monetary reward anticipation during smoking abstinence predicts lapse during a contingency-managed quit attempt. 
  • Can an old bird change his tune? 
  • Chronic very low dose naltrexone administration attenuates opioid withdrawal expression. 
  • Cocaine increases dopamine release by mobilization of a synapsin-dependent reserve pool. 
  • Colocalization of excitatory and inhibitory neurotransmitter markers in striatal projection neurons in the rat. 
  • Contributions of striatal subregions to place and response learning. 
  • Cortico-striatal synaptic defects and OCD-like behaviours in Sapap3-mutant mice. 
  • Decrements in auditory responses to a repeated conspecific song are long-lasting and require two periods of protein synthesis in the songbird forebrain. 
  • Differential neural responses to food images in women with bulimia versus anorexia nervosa. 
  • Dopamine uptake inhibitors but not dopamine releasers induce greater increases in motor behavior and extracellular dopamine in adolescent rats than in adult male rats. 
  • Effects of striatal nitric oxide production on regional cerebral blood flow and seizure development in rats exposed to extreme hyperoxia. 
  • GDNF protection against 6-OHDA-induced reductions in potassium-evoked overflow of striatal dopamine. 
  • Generation and behavioral characterization of beta-catenin forebrain-specific conditional knock-out mice. 
  • Global forebrain dynamics predict rat behavioral states and their transitions. 
  • Hydrogel-based three-dimensional matrix for neural cells. 
  • Intrinsic and extrinsic contributions to auditory selectivity in a song nucleus critical for vocal plasticity. 
  • Lateralization of prefrontal activity during episodic memory retrieval: evidence for the production-monitoring hypothesis. 
  • Lesions of an avian forebrain nucleus that disrupt song development alter synaptic connectivity and transmission in the vocal premotor pathway. 
  • Lesions of dorsolateral striatum preserve outcome expectancy but disrupt habit formation in instrumental learning. 
  • Magnetic resonance imaging at microscopic resolution reveals subtle morphological changes in a mouse model of dopaminergic hyperfunction. 
  • Magnetic resonance imaging in social phobia. 
  • Mechanism of regulation of casein kinase I activity by group I metabotropic glutamate receptors. 
  • Mesolimbic neuronal activity across behavioral states. 
  • Neuroprotective effects of creatine and cyclocreatine in animal models of Huntington's disease. 
  • Persistent cholinergic presynaptic deficits after neonatal chlorpyrifos exposure. 
  • Protection against focal cerebral ischemia following exposure to a pulsed electromagnetic field. 
  • Regressing to Prior Response Preference After Set Switching Implicates Striatal Dysfunction Across Psychotic Disorders: Findings From the B-SNIP Study. 
  • Reward-guided learning beyond dopamine in the nucleus accumbens: the integrative functions of cortico-basal ganglia networks. 
  • Selective defect of in vivo glycolysis in early Huntington's disease striatum. 
  • Shank3 mutant mice display autistic-like behaviours and striatal dysfunction. 
  • Spine pruning drives antipsychotic-sensitive locomotion via circuit control of striatal dopamine. 
  • Striatal fast-spiking interneurons selectively modulate circuit output and are required for habitual behavior. 
  • Synapsins differentially control dopamine and serotonin release. 
  • Synthesis and dopaminergic properties of benzo-fused analogues of quinpirole and quinelorane. 
  • The neural signatures of distinct psychopathic traits 
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  Keywords of People

  • Laskowitz, Daniel Todd, Professor of Neurology, Duke Science & Society