Culture Media, Conditioned
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Subject Areas on Research
- A constitutively active form of neurokinin 1 receptor and neurokinin 1 receptor-mediated apoptosis in glioblastomas.
- A manganese porphyrin superoxide dismutase mimetic enhances tumor radioresponsiveness.
- A non-transformed oligodendrocyte precursor cell line, OL-1, facilitates studies of insulin-like growth factor-I signaling during oligodendrocyte development.
- A soluble factor(s) secreted from CD8(+) T lymphocytes inhibits human immunodeficiency virus type 1 replication through STAT1 activation.
- Adipose stem cell crosstalk with chemo-residual breast cancer cells: implications for tumor recurrence.
- Angiogenesis-like activity of endothelial cells co-cultured with VEGF-producing smooth muscle cells.
- Angiotensin-converting enzyme 2 deficiency in whole body or bone marrow-derived cells increases atherosclerosis in low-density lipoprotein receptor-/- mice.
- Anti-phospholipid human monoclonal antibodies inhibit CCR5-tropic HIV-1 and induce beta-chemokines.
- Arterial gene transfer of the TGF-beta signalling protein Smad3 induces adaptive remodelling following angioplasty: a role for CTGF.
- Autocrine and paracrine effects of atrial natriuretic peptide gene transfer on vascular smooth muscle and endothelial cellular growth.
- CD8+ cell lines isolated from HIV-1-infected children have potent soluble HIV-1 inhibitory activity that differs from beta-chemokines.
- CRISPR/Cas9-Mediated BRCA1 Knockdown Adipose Stem Cells Promote Breast Cancer Progression.
- Calcium modulates the expression of urokinase plasminogen activator and plasminogen activator inhibitor 2 by human keratinocytes.
- Cardiac fibroblast paracrine factors alter impulse conduction and ion channel expression of neonatal rat cardiomyocytes.
- Cartilage viability and catabolism in the intact porcine knee following transarticular impact loading with and without articular fracture.
- Characterization of angiotensin-converting enzyme 2 ectodomain shedding from mouse proximal tubular cells.
- Conditioned medium differentially regulates matrix protein gene expression in cells of the intervertebral disc.
- Control of excitatory CNS synaptogenesis by astrocyte-secreted proteins Hevin and SPARC.
- Developmental stage-dependent effects of cardiac fibroblasts on function of stem cell-derived engineered cardiac tissues.
- Differentiation of mouse induced pluripotent stem cells (iPSCs) into nucleus pulposus-like cells in vitro.
- Effects of cartilage impact with and without fracture on chondrocyte viability and the release of inflammatory markers.
- Effects of chronic exposure to simulated microgravity on skeletal muscle cell proliferation and differentiation.
- Endothelial cell-conditioned medium downregulates smooth muscle contractile protein expression.
- Endothelial heparan sulfate is necessary but not sufficient for control of vascular smooth muscle cell growth.
- Endotoxin-stimulated Rat Hepatic Stellate Cells Induce Autophagy in Hepatocytes as a Survival Mechanism.
- Estrogen-induced mitogenesis of MCF-7 cells does not require the induction of mitogen-activated protein kinase activity.
- Evidence for a novel insulin-like growth factor (IGF)-dependent protease regulating IGF-binding protein-4 in dermal fibroblasts.
- Ex vivo pediatric brain tumors express Fas (CD95) and FasL (CD95L) and are resistant to apoptosis induction.
- Exposure to a youthful circulaton rejuvenates bone repair through modulation of β-catenin.
- Expression of transforming growth factor beta (TGFbeta) type III receptor restores autocrine TGFbeta1 activity in human breast cancer MCF-7 cells.
- Extracellular trafficking of myocilin in human trabecular meshwork cells.
- Fibroblast inhibition of tumor cells may be mediated by TGF-beta 1.
- Generation of EBV-specific CD4+ cytotoxic T cells from virus naive individuals.
- Global metabolic profiling of human osteoarthritic synovium.
- Glutathione peroxidase-deficient smooth muscle cells cause paracrine activation of normal smooth muscle cells via cyclophilin A.
- Hematopoietic stem cells convert into liver cells within days without fusion.
- Human CD34+ hematopoietic progenitors have low, cytokine-unresponsive O6-alkylguanine-DNA alkyltransferase and are sensitive to O6-benzylguanine plus BCNU.
- Human Umbilical Tissue-Derived Cells Promote Synapse Formation and Neurite Outgrowth via Thrombospondin Family Proteins.
- Human apolipoprotein E isoform-specific differences in neuronal sprouting in organotypic hippocampal culture.
- Human placental cytotrophoblasts attract monocytes and CD56(bright) natural killer cells via the actions of monocyte inflammatory protein 1alpha.
- Hyalocytes synthesize and secrete inhibitors of retinal pigment epithelial cell proliferation in vitro.
- Hypothesis testing for neural cell growth experiments using a hybrid branching process model.
- IL-13 and IL-1beta promote lung fibroblast growth through coordinated up-regulation of PDGF-AA and PDGF-Ralpha.
- Identification of a soluble form of B7-H1 that retains immunosuppressive activity and is associated with aggressive renal cell carcinoma.
- Impaired nitric oxide synthase-2 signaling pathway in cystic fibrosis airway epithelium.
- Induction of cyclooxygenase-2 in human endometrial stromal cells by malignant endometrial epithelial cells: evidence for the involvement of extracellularly regulated kinases and CCAAT/enhancer binding proteins.
- Inhibition of WNT signaling by G protein-coupled receptor (GPCR) kinase 2 (GRK2).
- Inhibition of tumor angiogenesis using a soluble receptor establishes a role for Tie2 in pathologic vascular growth.
- Injuring neurons induces neuronal differentiation in a population of hippocampal precursor cells in culture.
- Innate inhibition of adaptive immunity: Mycobacterium tuberculosis-induced IL-6 inhibits macrophage responses to IFN-gamma.
- Insulin-like growth factor binding protein 2 is a growth inhibitory protein conserved in zebrafish.
- Insulin-like growth factor-I is expressed by avian flexor tendon cells.
- Interaction of NG2(+) glial progenitors and microglia/macrophages from the injured spinal cord.
- Interleukin-15 augments superoxide production and microbicidal activity of human monocytes against Candida albicans.
- Invasion and MMP expression profile in desmoid tumours.
- LDL receptor-related protein 5 (LRP5) affects bone accrual and eye development.
- Malignant breast epithelial cells stimulate aromatase expression via promoter II in human adipose fibroblasts: an epithelial-stromal interaction in breast tumors mediated by CCAAT/enhancer binding protein beta.
- Malignant melanoma induces migration and invasion of adult mesenchymal stem cells.
- Matrix metalloproteinases degrade insulin-like growth factor-binding protein-3 in dermal fibroblast cultures.
- Melanoma-derived conditioned media efficiently induce the differentiation of monocytes to macrophages that display a highly invasive gene signature.
- Molecular characterization of hypoxia-hypothermia-conditioned human endothelial cells and their interaction with human monocytes.
- Morphogenetic signals from chondrocytes promote chondrogenic and osteogenic differentiation of mesenchymal stem cells.
- Notch1 perturbation of hemopoiesis involves non-cell- autonomous modifications.
- Novel cell-free strategy for therapeutic angiogenesis: in vitro generated conditioned medium can replace progenitor cell transplantation.
- Nucleotides released by apoptotic cells act as a find-me signal to promote phagocytic clearance.
- Osteoarthritic chondrocyte-secreted morphogens induce chondrogenic differentiation of human mesenchymal stem cells.
- PDGF-AA mediates mesenchymal stromal cell chemotaxis to the head and neck squamous cell carcinoma tumor microenvironment.
- Paracrine action accounts for marked protection of ischemic heart by Akt-modified mesenchymal stem cells.
- Paracrine factors secreted by endothelial progenitor cells prevent oxidative stress-induced apoptosis of mature endothelial cells.
- Phospholipid vesicles interfere with the binding of antibody fragments to the light chain of factor VIII.
- Physical exosome:exosome interactions.
- Pulmonary and pleural leukocytes from F344 rats produce elevated levels of fibronectin following inhalation of refractory ceramic fibers.
- Reactive mononuclear phagocytes release neurotoxins after ischemic and traumatic injury to the central nervous system.
- Recombinant human uteroglobin inhibits the in vitro invasiveness of human metastatic prostate tumor cells and the release of arachidonic acid stimulated by fibroblast-conditioned medium.
- Regulation of myocilin-associated exosome release from human trabecular meshwork cells.
- SECTM1 produced by tumor cells attracts human monocytes via CD7-mediated activation of the PI3K pathway.
- Secretion of extracellular matrix-degrading proteinases is increased in epithelial ovarian carcinoma.
- Selection of insulinoma cell lines with resistance to interleukin-1beta- and gamma-interferon-induced cytotoxicity.
- Sequestration of amyloid beta-peptide.
- Skeletal muscle-specific Cre recombinase expression, controlled by the human α-skeletal actin promoter, improves glucose tolerance in mice fed a high-fat diet.
- Soluble ICAM-1, MCP-1, and MIP-2 protein secretion by rat pleural mesothelial cells following exposure to amosite asbestos.
- The disulfide bonding pattern in ficolin multimers.
- The integrity of a cholesterol-binding pocket in Niemann-Pick C2 protein is necessary to control lysosome cholesterol levels.
- The mechanism of the auxotrophy for sulfur-containing amino acids imposed upon Escherichia coli by superoxide.
- Thrombospondins as key regulators of synaptogenesis in the central nervous system.
- Tissue engraftment of hypoxic-preconditioned adipose-derived stem cells improves flap viability.
- Tumor-induced loss of mural Connexin 43 gap junction activity promotes endothelial proliferation.
- Tumour-derived PTH-related protein triggers adipose tissue browning and cancer cachexia.
- Ultra-high expression of a thermally responsive recombinant fusion protein in E. coli.
- Up-regulation of the JAK/STAT1 signal pathway during Chlamydia trachomatis infection.
- Vascular endothelial growth factor promotes breast carcinoma invasion in an autocrine manner by regulating the chemokine receptor CXCR4.
- Vertebrate Lonesome Kinase Regulated Extracellular Matrix Protein Phosphorylation, Cell Shape, and Adhesion in Trabecular Meshwork Cells.
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Keywords of People
- Erickson, Harold Paul, James B. Duke Distinguished Professor of Cell Biology, Cell Biology
- Olson, Steven Arthur, Professor of Orthopaedic Surgery, Orthopaedics
- Sampson, John Howard, Robert H., M.D. and Gloria Wilkins Professor of Neurosurgery, in the School of Medicine, Immunology