Stromal Cells
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Subject Areas on Research
- A cell-intrinsic role for CaMKK2 in granulocyte lineage commitment and differentiation.
- A next-generation dual-recombinase system for time- and host-specific targeting of pancreatic cancer.
- A signature of epithelial-mesenchymal plasticity and stromal activation in primary tumor modulates late recurrence in breast cancer independent of disease subtype.
- Activation of Wnt signaling in hematopoietic regeneration.
- Addressing cell-sourcing limitations with gene therapy.
- An analysis of T cell intrinsic roles of E2A by conditional gene disruption in the thymus.
- Bile ductules and stromal cells express hedgehog ligands and/or hedgehog target genes in primary biliary cirrhosis.
- Bioluminescence imaging of glucose in tissue surrounding polyurethane and glucose sensor implants.
- Bone formation by human postnatal bone marrow stromal stem cells is enhanced by telomerase expression.
- Bone morphogenetic protein 4 regulates the budding site and elongation of the mouse ureter.
- CD34+CD38-lin- cord blood cells develop into dendritic cells in human thymic stromal monolayers and thymic nodules.
- CD83 expression influences CD4+ T cell development in the thymus.
- Cellular and molecular responses of the uterus to embryo implantation can be elicited by locally applied growth factors.
- Characterization of neuronal/glial differentiation of murine adipose-derived adult stromal cells.
- Chemotherapy and the bone marrow stroma.
- Chondrogenic potential of adipose tissue-derived stromal cells in vitro and in vivo.
- Circulating Cancer-Associated Macrophage-Like Cells Differentiate Malignant Breast Cancer and Benign Breast Conditions.
- Clinical Insights Into the Biology and Treatment of Pancreatic Cancer.
- Comparative and functional evaluation of in vitro generated to ex vivo CD8 T cells.
- Defective pericyte recruitment of villous stromal vessels as the possible etiologic cause of hydropic change in complete hydatidiform mole.
- Determination of estrogen receptor messenger ribonucleic acid (mRNA) and cytochrome P450 aromatase mRNA levels in adipocytes and adipose stromal cells by competitive polymerase chain reaction amplification.
- ERAP75 functions as a coactivator to enhance estrogen receptor alpha transactivation in prostate stromal cells.
- Ectopic overexpression of Sonic Hedgehog (Shh) induces stromal expansion and metaplasia in the adult murine pancreas.
- Embryonic germ cells are capable of adipogenic differentiation in vitro and in vivo.
- Epithelial repair of the uterine cervix: assessment of morphologic features and correlations with cytologic diagnosis.
- Epithelialization of hydrogels achieved by amine functionalization and co-culture with stromal cells.
- Establishment of a Novel Histopathological Classification of High-Grade Serous Ovarian Carcinoma Correlated with Prognostically Distinct Gene Expression Subtypes.
- Evaluation of candidate stromal epithelial cross-talk genes identifies association between risk of serous ovarian cancer and TERT, a cancer susceptibility "hot-spot".
- Ex vivo glycan engineering of CD44 programs human multipotent mesenchymal stromal cell trafficking to bone.
- Expression of androgen and estrogen related proteins in normal weight and obese prostate cancer patients.
- FOXP3-positive regulatory T lymphocytes and epithelial FOXP3 expression in synchronous normal, ductal carcinoma in situ, and invasive cancer of the breast.
- Fine-needle aspiration of gastrointestinal stromal tumors.
- Flow cytometric analysis of intercellular adhesion between B-cell precursor acute lymphoblastic leukemic cells and bone marrow stromal cells.
- Functional analysis of two distinct bronchiolar progenitors during lung injury and repair.
- Galectin-1 accumulation in the ovary carcinoma peritumoral stroma is induced by ovary carcinoma cells and affects both cancer cell proliferation and adhesion to laminin-1 and fibronectin.
- Gastric stromal tumor.
- Glucocorticoid-induced osteogenesis is negatively regulated by Runx2/Cbfa1 serine phosphorylation.
- Human mesenchymal stem cells exert potent antitumorigenic effects in a model of Kaposi's sarcoma.
- Hypermethylation of 14-3-3 sigma (stratifin) is an early event in breast cancer.
- IFATS collection: Adipose-derived stromal cells improve the foreign body response.
- Immunophenotype of human adipose-derived cells: temporal changes in stromal-associated and stem cell-associated markers.
- Increased AKT or MEK1/2 activity influences progesterone receptor levels and localization in endometriosis.
- Increased production of sonic hedgehog by ballooned hepatocytes.
- Induced sensitization of tumor stroma leads to eradication of established cancer by T cells.
- Induction of ductal and stromal hyperplasia by basic fibroblast growth factor produced by human pancreatic carcinoma.
- Inflammation controls B lymphopoiesis by regulating chemokine CXCL12 expression.
- Insight into the molecular pathophysiology of myelodysplastic syndromes: targets for novel therapy.
- Insights from a chimpanzee adipose stromal cell population: opportunities for adult stem cells to expand primate functional genomics.
- Interleukin-1beta elevates cyclooxygenase-2 protein level and enzyme activity via increasing its mRNA stability in human endometrial stromal cells: an effect mediated by extracellularly regulated kinases 1 and 2.
- Intrathecal bone marrow stromal cells inhibit neuropathic pain via TGF-β secretion.
- Isolation and characterization of a novel human prostatic stromal cell culture: DuK50.
- LDL receptor-related protein 5 (LRP5) affects bone accrual and eye development.
- Laser capture microdissection in 2-D co-culture models as a tool to study tumor-stroma interactions.
- Late-outgrowth endothelial progenitors from patients with coronary artery disease: endothelialization of confluent stromal cell layers.
- Ligand binding and activation of PPARγ by Firemaster® 550: effects on adipogenesis and osteogenesis in vitro.
- Macrophage cells secrete factors including LRP1 that orchestrate the rejuvenation of bone repair in mice.
- Maintenance of T cell specification and differentiation requires recurrent notch receptor-ligand interactions.
- Marrow cell transplantation for infantile hypophosphatasia.
- Menstrual cyclic change of metastin/GPR54 in endometrium.
- Mesenchymal stromal cells alone or expressing interferon-beta suppress pancreatic tumors in vivo, an effect countered by anti-inflammatory treatment.
- Multiple stromal populations contribute to pulmonary fibrosis without evidence for epithelial to mesenchymal transition.
- NOTCH signaling in skeletal progenitors is critical for fracture repair.
- NOTCH-Mediated Maintenance and Expansion of Human Bone Marrow Stromal/Stem Cells: A Technology Designed for Orthopedic Regenerative Medicine.
- Neurogenic differentiation of murine and human adipose-derived stromal cells.
- Obligatory role for cooperative signaling by pre-TCR and Notch during thymocyte differentiation.
- Optimization of a widefield structured illumination microscope for non-destructive assessment and quantification of nuclear features in tumor margins of a primary mouse model of sarcoma.
- Osteopontin promotes CCL5-mesenchymal stromal cell-mediated breast cancer metastasis.
- PDGFRα+ pericryptal stromal cells are the critical source of Wnts and RSPO3 for murine intestinal stem cells in vivo.
- Peritoneal and subperitoneal stroma may facilitate regional spread of ovarian cancer.
- Polymorphisms in stromal genes and susceptibility to serous epithelial ovarian cancer: a report from the Ovarian Cancer Association Consortium.
- Relationship between adipose stromal-vascular cells and adipocytes in human adipose tissue.
- Repair-related activation of hedgehog signaling in stromal cells promotes intrahepatic hypothyroidism.
- Stroma provides an intestinal stem cell niche in the absence of epithelial Wnts.
- Stromal cell independent B cell development in vitro: generation and recovery of autoreactive clones.
- Stromal complement receptor CD21/35 facilitates lymphoid prion colonization and pathogenesis.
- Stromal gene signatures in large-B-cell lymphomas.
- Stromal heparan sulfate differentiates neuroblasts to suppress neuroblastoma growth.
- Stromal-epithelial crosstalk regulates kidney progenitor cell differentiation.
- Targeting eNOS in pancreatic cancer.
- Telomere dysfunction causes alveolar stem cell failure.
- Temporal transcriptional profiling of somatic and germ cells reveals biased lineage priming of sexual fate in the fetal mouse gonad.
- Tenascin and microvessel stromal changes in patients with non-Hodgkin's lymphoma are isolated to the sites of disease and vary in correlation to disease activity.
- The cytolytic molecules Fas ligand and TRAIL are required for murine thymic graft-versus-host disease.
- The dynamics of bone marrow stromal cells in the proliferation of multipotent hematopoietic progenitors by substance P: an understanding of the effects of a neurotransmitter on the differentiating hematopoietic stem cell.
- The effect of alpha1-adrenergic receptor antagonist tamsulosin (Flomax) on iris dilator smooth muscle anatomy.
- The type III transforming growth factor-β receptor inhibits proliferation, migration, and adhesion in human myeloma cells.
- Type 2 alveolar cells are stem cells in adult lung.
- Vasoactive intestinal peptide (VIP) inhibits the proliferation of bone marrow progenitors through the VPAC1 receptor.
- Vulvar vascular tumors: a clinicopathologic study of 85 patients.
- WT1 and DAX-1 inhibit aromatase P450 expression in human endometrial and endometriotic stromal cells.
- miR-126 and miR-126* repress recruitment of mesenchymal stem cells and inflammatory monocytes to inhibit breast cancer metastasis.
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Keywords of People
- Berchuck, Andrew, James M. Ingram Professor of Gynecologic Oncology, Obstetrics and Gynecology, Gynecologic Oncology
- Ciofani, Maria, Assistant Professor of Immunology, Immunology
- Hogan, Brigid L. M., George Barth Geller Professor, Cell Biology
- Kelsoe, Garnett H., James B. Duke Professor of Immunology, Immunology
- McCall, Shannon Jones, Associate Professor of Pathology, Pathology
- Pang, Herbert, Adjunct Assistant Professor in the Department of Biostatistics and Bioinformatics, Biostatistics & Bioinformatics
- Wray, Gregory Allan, Professor of Biology, Duke Innovation & Entrepreneurship