Caenorhabditis elegans

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  Subject Areas on Research

  • A CaMK cascade activates CRE-mediated transcription in neurons of Caenorhabditis elegans. 
  • A Decade of CRISPR-Cas Gnome Editing in C. elegans . 
  • A Farnesyltransferase Acts to Inhibit Ectopic Neurite Formation in C. elegans. 
  • A Sensitized Screen for Genes Promoting Invadopodia Function In Vivo: CDC-42 and Rab GDI-1 Direct Distinct Aspects of Invadopodia Formation. 
  • A basement membrane discovery pipeline uncovers network complexity, regulators, and human disease associations. 
  • A caspase homolog keeps CED-3 in check. 
  • A conserved PMK-1/p38 MAPK is required in caenorhabditis elegans tissue-specific immune response to Yersinia pestis infection. 
  • A conserved Toll-like receptor is required for Caenorhabditis elegans innate immunity. 
  • A conserved retromer-independent function for RAB-6.2 in C. elegans epidermis integrity. 
  • A conserved sorting-associated protein is mutant in chorea-acanthocytosis. 
  • A developmental biologist's "outside-the-cell" thinking. 
  • A new front in cell invasion: The invadopodial membrane. 
  • A proteomics approach to the identification of mammalian mitochondrial small subunit ribosomal proteins. 
  • A regulatory cascade of three homeobox genes, ceh-10, ttx-3 and ceh-23, controls cell fate specification of a defined interneuron class in C. elegans. 
  • A stress-sensitive reporter predicts longevity in isogenic populations of Caenorhabditis elegans. 
  • A ubiquitin E2 variant protein acts in axon termination and synaptogenesis in Caenorhabditis elegans. 
  • ADF/cofilin promotes invadopodial membrane recycling during cell invasion in vivo. 
  • Acoustofluidic Rotational Manipulation of Cells and Organisms Using Oscillating Solid Structures. 
  • Adaptive F-Actin Polymerization and Localized ATP Production Drive Basement Membrane Invasion in the Absence of MMPs. 
  • Age-specific demographic profiles of longevity mutants in Caenorhabditis elegans show segmental effects. 
  • Ageing and survival after different doses of heat shock: the results of analysis of data from stress experiments with the nematode worm Caenorhabditis elegans. 
  • Alternative somatic and germline gene-regulatory strategies during starvation-induced developmental arrest. 
  • Amelioration of metal-induced toxicity in Caenorhabditis elegans: utility of chelating agents in the bioremediation of metals. 
  • An Antimicrobial Peptide and Its Neuronal Receptor Regulate Dendrite Degeneration in Aging and Infection. 
  • Analysis of the genotype and virulence of Staphylococcus epidermidis isolates from patients with infective endocarditis. 
  • Anchor cell invasion into the vulval epithelium in C. elegans. 
  • Antagonistic Growth Effects of Mercury and Selenium in Caenorhabditis elegans Are Chemical-Species-Dependent and Do Not Depend on Internal Hg/Se Ratios. 
  • Antibiotic and antimalarial quinones from fungus-growing ant-associated Pseudonocardia sp. 
  • Assessing different mechanisms of toxicity in mountaintop removal/valley fill coal mining-affected watershed samples using Caenorhabditis elegans. 
  • Axon regeneration pathways identified by systematic genetic screening in C. elegans. 
  • B-LINK: a hemicentin, plakin, and integrin-dependent adhesion system that links tissues by connecting adjacent basement membranes. 
  • Balancing selection maintains hyper-divergent haplotypes in Caenorhabditis elegans. 
  • Basement Membranes in the Worm: A Dynamic Scaffolding that Instructs Cellular Behaviors and Shapes Tissues. 
  • Basement membrane sliding and targeted adhesion remodels tissue boundaries during uterine-vulval attachment in Caenorhabditis elegans. 
  • Basement membranes. 
  • Behavioral deficits during early stages of aging in Caenorhabditis elegans result from locomotory deficits possibly linked to muscle frailty. 
  • Boundary cells restrict dystroglycan trafficking to control basement membrane sliding during tissue remodeling. 
  • Brain insulin lowers circulating BCAA levels by inducing hepatic BCAA catabolism. 
  • C. elegans as a model to study glial development. 
  • CAPER is vital for energy and redox homeostasis by integrating glucose-induced mitochondrial functions via ERR-α-Gabpa and stress-induced adaptive responses via NF-κB-cMYC. 
  • CRISPR-Cas9-Guided Genome Engineering in C. elegans. 
  • CRISPR-Cas9-Guided Genome Engineering in Caenorhabditis elegans. 
  • Caenorhabditis elegans DNA mismatch repair gene msh-2 is required for microsatellite stability and maintenance of genome integrity. 
  • Caenorhabditis elegans as a Model for Toxic Effects of Nanoparticles: Lethality, Growth, and Reproduction. 
  • Caenorhabditis elegans as an emerging model system in environmental epigenetics. 
  • Caenorhabditis elegans beta-G spectrin is dispensable for establishment of epithelial polarity, but essential for muscular and neuronal function. 
  • Caenorhabditis elegans cog-1 locus encodes GTX/Nkx6.1 homeodomain proteins and regulates multiple aspects of reproductive system development. 
  • Caenorhabditis elegans generates biologically relevant levels of genotoxic metabolites from aflatoxin B1 but not benzo[a]pyrene in vivo 
  • Caenorhabditis elegans-based screen identifies Salmonella virulence factors required for conserved host-pathogen interactions. 
  • Caenorhabditis elegans: an emerging model in biomedical and environmental toxicology. 
  • Cell Invasion In Vivo via Rapid Exocytosis of a Transient Lysosome-Derived Membrane Domain. 
  • Cell division and targeted cell cycle arrest opens and stabilizes basement membrane gaps. 
  • Cell invasion through basement membrane: the anchor cell breaches the barrier. 
  • Cell invasion through basement membranes: an anchor of understanding. 
  • Cerium oxide nanoparticles are more toxic than equimolar bulk cerium oxide in Caenorhabditis elegans. 
  • Chromosome-Level Reference Genomes for Two Strains of Caenorhabditis briggsae: An Improved Platform for Comparative Genomics. 
  • Combinatorial expression of TRPV channel proteins defines their sensory functions and subcellular localization in C. elegans neurons. 
  • Comparative analysis of metazoan chromatin organization. 
  • Comparative toxicity of silver nanoparticles on oxidative stress and DNA damage in the nematode, Caenorhabditis elegans. 
  • Comparison of proteomic and metabolomic profiles of mutants of the mitochondrial respiratory chain in Caenorhabditis elegans. 
  • Composition and dynamics of the Caenorhabditis elegans early embryonic transcriptome. 
  • Comprehensive Endogenous Tagging of Basement Membrane Components Reveals Dynamic Movement within the Matrix Scaffolding. 
  • Cryptococcus neoformans Kin1 protein kinase homologue, identified through a Caenorhabditis elegans screen, promotes virulence in mammals. 
  • Cryptococcus neoformans gene involved in mammalian pathogenesis identified by a Caenorhabditis elegans progeny-based approach. 
  • Cryptococcus neoformans {alpha} strains preferentially disseminate to the central nervous system during coinfection. 
  • Cysteine 70 of ankyrin-G is S-palmitoylated and is required for function of ankyrin-G in membrane domain assembly. 
  • DAF-16/FOXO regulates transcription of cki-1/Cip/Kip and repression of lin-4 during C. elegans L1 arrest. 
  • DAF-18/PTEN inhibits germline zygotic gene activation during primordial germ cell quiescence. 
  • DEPDC1/LET-99 participates in an evolutionarily conserved pathway for anti-tubulin drug-induced apoptosis. 
  • Decline of nucleotide excision repair capacity in aging Caenorhabditis elegans. 
  • Deficiencies in mitochondrial dynamics sensitize Caenorhabditis elegans to arsenite and other mitochondrial toxicants by reducing mitochondrial adaptability. 
  • Detection of broadly expressed neuronal genes in C. elegans. 
  • Dietary Restriction and AMPK Increase Lifespan via Mitochondrial Network and Peroxisome Remodeling. 
  • Dietary serine-microbiota interaction enhances chemotherapeutic toxicity without altering drug conversion. 
  • Differential regulation of polarized synaptic vesicle trafficking and synapse stability in neural circuit rewiring in Caenorhabditis elegans. 
  • Dissection of genetic pathways in C. elegans. 
  • Drebrin-like protein DBN-1 is a sarcomere component that stabilizes actin filaments during muscle contraction. 
  • Dynamic microtubules drive circuit rewiring in the absence of neurite remodeling. 
  • Early-life mitochondrial DNA damage results in lifelong deficits in energy production mediated by redox signaling in Caenorhabditis elegans. 
  • Early-life starvation alters lipid metabolism in adults to cause developmental pathology in Caenorhabditis elegans. 
  • Eca1, a sarcoplasmic/endoplasmic reticulum Ca2+-ATPase, is involved in stress tolerance and virulence in Cryptococcus neoformans. 
  • Ectopic Germ Cells Can Induce Niche-like Enwrapment by Neighboring Body Wall Muscle. 
  • Effects of 5'-fluoro-2-deoxyuridine on mitochondrial biology in Caenorhabditis elegans. 
  • Effects of early life exposure to ultraviolet C radiation on mitochondrial DNA content, transcription, ATP production, and oxygen consumption in developing Caenorhabditis elegans. 
  • Effects of methyl and inorganic mercury exposure on genome homeostasis and mitochondrial function in Caenorhabditis elegans. 
  • Effects of microgravity on the virulence of Listeria monocytogenes, Enterococcus faecalis, Candida albicans, and methicillin-resistant Staphylococcus aureus. 
  • Effects of reduced mitochondrial DNA content on secondary mitochondrial toxicant exposure in Caenorhabditis elegans. 
  • Efficient Genome Editing in Caenorhabditis elegans with a Toolkit of Dual-Marker Selection Cassettes. 
  • Evolutionarily conserved role of calcineurin in phosphodegron-dependent degradation of phosphodiesterase 4D. 
  • Expanding views of presynaptic terminals: new findings from Caenorhabditis elegans. 
  • Exposure to mitochondrial genotoxins and dopaminergic neurodegeneration in Caenorhabditis elegans. 
  • FOS-1 promotes basement-membrane removal during anchor-cell invasion in C. elegans. 
  • Fanconi Anemia FANCM/FNCM-1 and FANCD2/FCD-2 Are Required for Maintaining Histone Methylation Levels and Interact with the Histone Demethylase LSD1/SPR-5 in Caenorhabditis elegans . 
  • Fertility/longevity trade-offs under limiting-male conditions in mating populations of Caenorhabditis elegans. 
  • Fluorescence-based sorting of Caenorhabditis elegans via acoustofluidics. 
  • Food perception without ingestion leads to metabolic changes and irreversible developmental arrest in C. elegans. 
  • Forces drive basement membrane invasion in Caenorhabditis elegans . 
  • From the Cover: Arsenite Uncouples Mitochondrial Respiration and Induces a Warburg-like Effect in Caenorhabditis elegans. 
  • Functional mapping of neurons that control locomotory behavior in Caenorhabditis elegans. 
  • Functionality of the TRPV subfamily of TRP ion channels: add mechano-TRP and osmo-TRP to the lexicon! 
  • G protein-coupled receptor kinase function is essential for chemosensation in C. elegans. 
  • G protein-coupled receptor kinase-2 (GRK-2) regulates serotonin metabolism through the monoamine oxidase AMX-2 in Caenorhabditis elegans. 
  • GABA signaling triggered by TMC-1/Tmc delays neuronal aging by inhibiting the PKC pathway in C. elegans. 
  • GenBlastA: enabling BLAST to identify homologous gene sequences. 
  • Gene expression markers for Caenorhabditis elegans vulval cells. 
  • Gene expression markers for Caenorhabditis elegans vulval cells. 
  • Genetic Defects in Mitochondrial Dynamics in Caenorhabditis elegans Impact Ultraviolet C Radiation- and 6-hydroxydopamine-Induced Neurodegeneration. 
  • Genetic Screen Reveals Link between the Maternal Effect Sterile Gene mes-1 and Pseudomonas aeruginosa-induced Neurodegeneration in Caenorhabditis elegans. 
  • Genetic analysis of daf-18/PTEN missense mutants for starvation resistance and developmental regulation during Caenorhabditis elegans L1 arrest. 
  • Genetic dissection of late-life fertility in Caenorhabditis elegans. 
  • Germline signaling mediates the synergistically prolonged longevity produced by double mutations in daf-2 and rsks-1 in C. elegans. 
  • Graph Matching: Relax at Your Own Risk. 
  • Heat shock changes the heterogeneity distribution in populations of Caenorhabditis elegans: does it tell us anything about the biological mechanism of stress response? 
  • Heating stress patterns in Caenorhabditis elegans longevity and survivorship. 
  • Hemicentin-mediated type IV collagen assembly strengthens juxtaposed basement membrane linkage. 
  • High-throughput phenotyping of multicellular organisms: finding the link between genotype and phenotype. 
  • Histone demethylase AMX-1 is necessary for proper sensitivity to interstrand crosslink DNA damage. 
  • Hormesis and debilitation effects in stress experiments using the nematode worm Caenorhabditis elegans: the model of balance between cell damage and HSP levels. 
  • How the analysis of genetic mutations can help us to solve basic problems in gerontology? I. Life extending genetic modifications in round worm C. elegans. 
  • Human Bcl-2 cannot directly inhibit the Caenorhabditis elegans Apaf-1 homologue CED-4, but can interact with EGL-1. 
  • Identification and characterization of two Ca2+/CaM-dependent protein kinases required for normal nuclear division in Aspergillus nidulans. 
  • Identification of four proteins from the small subunit of the mammalian mitochondrial ribosome using a proteomics approach. 
  • Identification of late larval stage developmental checkpoints in Caenorhabditis elegans regulated by insulin/IGF and steroid hormone signaling pathways. 
  • Identification of regulators of germ stem cell enwrapment by its niche in C. elegans. 
  • In Vivo Determination of Mitochondrial Function Using Luciferase-Expressing Caenorhabditis elegans: Contribution of Oxidative Phosphorylation, Glycolysis, and Fatty Acid Oxidation to Toxicant-Induced Dysfunction. 
  • In situ imaging in C. elegans reveals developmental regulation of microtubule dynamics. 
  • In vivo identification of regulators of cell invasion across basement membranes. 
  • In vivo repair of alkylating and oxidative DNA damage in the mitochondrial and nuclear genomes of wild-type and glycosylase-deficient Caenorhabditis elegans 
  • Ins-4 and daf-28 function redundantly to regulate C. elegans L1 arrest. 
  • Insulin-like signalling to the maternal germline controls progeny response to osmotic stress. 
  • Insulin/IGF Signaling and Vitellogenin Provisioning Mediate Intergenerational Adaptation to Nutrient Stress. 
  • Insulin/IGF-dependent Wnt signaling promotes formation of germline tumors and other developmental abnormalities following early-life starvation in Caenorhabditis elegans. 
  • Integrin acts upstream of netrin signaling to regulate formation of the anchor cell's invasive membrane in C. elegans. 
  • Intergenerational adaptations to stress are evolutionarily conserved, stress-specific, and have deleterious trade-offs. 
  • Interplay between structure-specific endonucleases for crossover control during Caenorhabditis elegans meiosis. 
  • Intracellular trafficking pathways in silver nanoparticle uptake and toxicity in Caenorhabditis elegans. 
  • Intracellular uptake and associated toxicity of silver nanoparticles in Caenorhabditis elegans 
  • Invading, Leading and Navigating Cells in Caenorhabditis elegans : Insights into Cell Movement in Vivo . 
  • Invadopodia and basement membrane invasion in vivo. 
  • Invasive Cell Fate Requires G1 Cell-Cycle Arrest and Histone Deacetylase-Mediated Changes in Gene Expression. 
  • Invertebrate nociception: behaviors, neurons and molecules. 
  • Involvement of autophagy and mitochondrial dynamics in determining the fate and effects of irreparable mitochondrial DNA damage. 
  • Killing of Caenorhabditis elegans by Cryptococcus neoformans as a model of yeast pathogenesis. 
  • LAD-1, the Caenorhabditis elegans L1CAM homologue, participates in embryonic and gonadal morphogenesis and is a substrate for fibroblast growth factor receptor pathway-dependent phosphotyrosine-based signaling. 
  • LIM homeobox gene-dependent expression of biogenic amine receptors in restricted regions of the C. elegans nervous system. 
  • Lattice light-sheet microscopy: imaging molecules to embryos at high spatiotemporal resolution. 
  • Less is more: compact genomes pay dividends. 
  • Liquid-culture protocols for synchronous starvation, growth, dauer formation, and dietary restriction of Caenorhabditis elegans . 
  • Live-cell confocal microscopy and quantitative 4D image analysis of anchor-cell invasion through the basement membrane in Caenorhabditis elegans. 
  • Longevity and stress in Caenorhabditis elegans. 
  • MANF deletion abrogates early larval Caenorhabditis elegans stress response to tunicamycin and Pseudomonas aeruginosa. 
  • MAP kinase signaling specificity mediated by the LIN-1 Ets/LIN-31 WH transcription factor complex during C. elegans vulval induction. 
  • MIG-10 (Lamellipodin) stabilizes invading cell adhesion to basement membrane and is a negative transcriptional target of EGL-43 in C. elegans. 
  • MIG-10 (lamellipodin) has netrin-independent functions and is a FOS-1A transcriptional target during anchor cell invasion in C. elegans. 
  • MRCK-1 Drives Apical Constriction in C. elegans by Linking Developmental Patterning to Force Generation. 
  • Mammalian TRPV4 (VR-OAC) directs behavioral responses to osmotic and mechanical stimuli in Caenorhabditis elegans. 
  • Maternal Diet and Insulin-Like Signaling Control Intergenerational Plasticity of Progeny Size and Starvation Resistance. 
  • Meiotic mutants that cause a polar decrease in recombination on the X chromosome in Caenorhabditis elegans. 
  • MicroRNAs both promote and antagonize longevity in C. elegans. 
  • Mitochondria as a target of organophosphate and carbamate pesticides: Revisiting common mechanisms of action with new approach methodologies. 
  • Mitochondrial DNA variant in COX1 subunit significantly alters energy metabolism of geographically divergent wild isolates in Caenorhabditis elegans. 
  • Mitochondrial Morphology and Fundamental Parameters of the Mitochondrial Respiratory Chain Are Altered in Caenorhabditis elegans Strains Deficient in Mitochondrial Dynamics and Homeostasis Processes. 
  • Mitochondrial bioenergetic changes during development as an indicator of C. elegans health-span. 
  • Mitochondrial dynamics and autophagy aid in removal of persistent mitochondrial DNA damage in Caenorhabditis elegans 
  • Molecular and genetic approaches for the analysis of C. elegans neuronal development. 
  • Molecular mechanisms of TRPV4-mediated neural signaling. 
  • Morphogenesis of the caenorhabditis elegans vulva. 
  • Mortality shifts in Caenorhabditis elegans: remembrance of conditions past. 
  • MultiFocus Polarization Microscope (MF-PolScope) for 3D polarization imaging of up to 25 focal planes simultaneously. 
  • Multiple metabolic changes mediate the response of Caenorhabditis elegans to the complex I inhibitor rotenone. 
  • Multiple mild heat-shocks decrease the Gompertz component of mortality in Caenorhabditis elegans. 
  • Multiple time scales in simple habituation. 
  • MyoD, modularity, and myogenesis: conservation of regulators and redundancy in C. elegans. 
  • N-terminal acetylation promotes synaptonemal complex assembly in C. elegans. 
  • NLR-1/CASPR Anchors F-Actin to Promote Gap Junction Formation. 
  • NatB domain-containing CRA-1 antagonizes hydrolase ACER-1 linking acetyl-CoA metabolism to the initiation of recombination during C. elegans meiosis. 
  • Neurohormonal signaling via a sulfotransferase antagonizes insulin-like signaling to regulate a Caenorhabditis elegans stress response. 
  • Neuroligin-mediated neurodevelopmental defects are induced by mitochondrial dysfunction and prevented by lutein in C. elegans. 
  • Neuronal CRTC-1 governs systemic mitochondrial metabolism and lifespan via a catecholamine signal. 
  • Neuronal cell shape and neurite initiation are regulated by the Ndr kinase SAX-1, a member of the Orb6/COT-1/warts serine/threonine kinase family. 
  • New Insights into the Post-Translational Regulation of DNA Damage Response and Double-Strand Break Repair in Caenorhabditis elegans. 
  • Newly Revised Quantitative PCR-Based Assay for Mitochondrial and Nuclear DNA Damage. 
  • Nonconsensus Protein Binding to Repetitive DNA Sequence Elements Significantly Affects Eukaryotic Genomes. 
  • Nongenetic inheritance and multigenerational plasticity in the nematode C. elegans. 
  • Nonselective autophagy reduces mitochondrial content during starvation in Caenorhabditis elegans. 
  • Nucleosome Turnover Regulates Histone Methylation Patterns over the Genome. 
  • Nucleotide excision repair genes are expressed at low levels and are not detectably inducible in Caenorhabditis elegans somatic tissues, but their function is required for normal adult life after UVC exposure 
  • Nutritional control of mRNA isoform expression during developmental arrest and recovery in C. elegans. 
  • Olfactory recognition and discrimination in Caenorhabditis elegans. 
  • Optofluidic microscopy--a method for implementing a high resolution optical microscope on a chip. 
  • PCR based determination of mitochondrial DNA copy number in multiple species. 
  • PCR-Based Determination of Mitochondrial DNA Copy Number in Multiple Species. 
  • Pairing of competitive and topologically distinct regulatory modules enhances patterned gene expression. 
  • Patterns of flanking sequence conservation and a characteristic upstream motif for microRNA gene identification. 
  • Pervasive Positive and Negative Feedback Regulation of Insulin-Like Signaling in Caenorhabditis elegans . 
  • Phosphorylation of FEZ1 by Microtubule Affinity Regulating Kinases regulates its function in presynaptic protein trafficking. 
  • Physiological roles of the Ca2+/CaM-dependent protein kinase cascade in health and disease. 
  • Pol II docking and pausing at growth and stress genes in C. elegans. 
  • Population Selection and Sequencing of Caenorhabditis elegans Wild Isolates Identifies a Region on Chromosome III Affecting Starvation Resistance. 
  • Predicting longevity in C. elegans: fertility, mobility and gene expression. 
  • Probing domain interactions in soluble guanylate cyclase. 
  • Quantifying Levels of Dopaminergic Neuron Morphological Alteration and Degeneration in Caenorhabditis elegans. 
  • Quantitative analysis of mRNA amplification by in vitro transcription. 
  • RAB-10-Dependent Membrane Transport Is Required for Dendrite Arborization. 
  • RNA Pol II accumulates at promoters of growth genes during developmental arrest. 
  • Regulation of DLK-1 kinase activity by calcium-mediated dissociation from an inhibitory isoform. 
  • Regulation of Gap Junction Dynamics by UNC-44/ankyrin and UNC-33/CRMP through VAB-8 in C. elegans Neurons. 
  • Regulation of Gliogenesis by lin-32/Atoh1 in Caenorhabditis elegans. 
  • Regulation of glial size by eicosapentaenoic acid through a novel Golgi apparatus mechanism. 
  • Regulation of neuronal axon specification by glia-neuron gap junctions in C. elegans. 
  • Repurposing an endogenous degradation system for rapid and targeted depletion of C. elegans proteins. 
  • Resistance of mitochondrial DNA to cadmium and Aflatoxin B1 damage-induced germline mutation accumulation in C. elegans. 
  • Robo functions as an attractive cue for glial migration through SYG-1/Neph. 
  • Robust test method for time-course microarray experiments. 
  • Role of TRPV ion channels in sensory transduction of osmotic stimuli in mammals. 
  • Roles for netrin signaling outside of axon guidance: a view from the worm. 
  • Rotenone Modulates Caenorhabditis elegans Immunometabolism and Pathogen Susceptibility. 
  • SPARC Promotes Cell Invasion In Vivo by Decreasing Type IV Collagen Levels in the Basement Membrane. 
  • Seahorse Xfe 24 Extracellular Flux Analyzer-Based Analysis of Cellular Respiration in Caenorhabditis elegans. 
  • Sensitive and precise quantification of insulin-like mRNA expression in Caenorhabditis elegans. 
  • Shifting gears and putting on the brakes: Female germ cells transition into meiosis. 
  • Signaling specificity: the RTK/RAS/MAP kinase pathway in metazoans. 
  • Silver nanoparticle behavior, uptake, and toxicity in Caenorhabditis elegans: effects of natural organic matter. 
  • Silver nanoparticle toxicity to Atlantic killifish (Fundulus heteroclitus) and Caenorhabditis elegans: a comparison of mesocosm, microcosm, and conventional laboratory studies. 
  • Social feeding in Caenorhabditis elegans is induced by neurons that detect aversive stimuli. 
  • Spatiotemporal regulation of Aurora B recruitment ensures release of cohesion during C. elegans oocyte meiosis. 
  • Staging worms for next-generation analysis. 
  • Starvation Responses Throughout the Caenorhabditis elegans Life Cycle. 
  • Stem cell niche exit in C. elegans via orientation and segregation of daughter cells by a cryptic cell outside the niche. 
  • Stem cells: A tale of two kingdoms. 
  • Strengths and limitations of morphological and behavioral analyses in detecting dopaminergic deficiency in Caenorhabditis elegans. 
  • Stress and death: breaking up the c-Abl/14-3-3 complex in apoptosis. 
  • Succinylated octopamine ascarosides and a new pathway of biogenic amine metabolism in Caenorhabditis elegans. 
  • Sulfidation of silver nanoparticles: natural antidote to their toxicity. 
  • Surface acoustic waves enable rotational manipulation of Caenorhabditis elegans. 
  • Survival defects of Cryptococcus neoformans mutants exposed to human cerebrospinal fluid result in attenuated virulence in an experimental model of meningitis. 
  • Swim exercise in Caenorhabditis elegans extends neuromuscular and gut healthspan, enhances learning ability, and protects against neurodegeneration. 
  • Swimming Exercise and Transient Food Deprivation in Caenorhabditis elegans Promote Mitochondrial Maintenance and Protect Against Chemical-Induced Mitotoxicity. 
  • Synthetic lethal analysis of Caenorhabditis elegans posterior embryonic patterning genes identifies conserved genetic interactions. 
  • TMEM231, mutated in orofaciodigital and Meckel syndromes, organizes the ciliary transition zone. 
  • TRPV channel-mediated calcium transients in nociceptor neurons are dispensable for avoidance behaviour. 
  • TRPV channels' role in osmotransduction and mechanotransduction. 
  • TRPV4 as osmosensor: a transgenic approach. 
  • The Caenorhabditis elegans ABL-1 tyrosine kinase is required for Shigella flexneri pathogenesis. 
  • The Caenorhabditis elegans CED-9 protein does not directly inhibit the caspase CED-3, in vitro nor in yeast. 
  • The Caenorhabditis elegans anchor cell transcriptome: ribosome biogenesis drives cell invasion through basement membrane. 
  • The Cell Death Pathway Regulates Synapse Elimination through Cleavage of Gelsolin in Caenorhabditis elegans Neurons. 
  • The DLK-1 kinase promotes mRNA stability and local translation in C. elegans synapses and axon regeneration. 
  • The U-shaped response of initial mortality in Caenorhabditis elegans to mild heat shock: does it explain recent trends in human mortality? 
  • The genome's best friend. 
  • The homeodomain protein PAL-1 specifies a lineage-specific regulatory network in the C. elegans embryo. 
  • The mechanism of silver nanoparticle toxicity is dependent on dissolved silver and surface coating in Caenorhabditis elegans 
  • The netrin receptor DCC focuses invadopodia-driven basement membrane transmigration in vivo. 
  • The small subunit of the mammalian mitochondrial ribosome. Identification of the full complement of ribosomal proteins present. 
  • The tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) induces mitochondrial and nuclear DNA damage in Caenorhabditis elegans. 
  • The transcription factor HLH-2/E/Daughterless regulates anchor cell invasion across basement membrane in C. elegans. 
  • The trehalose synthesis pathway is an integral part of the virulence composite for Cryptococcus gattii. 
  • The unfolded protein response is required for dendrite morphogenesis. 
  • Tissue linkage through adjoining basement membranes: The long and the short term of it. 
  • To grow or not to grow: nutritional control of development during Caenorhabditis elegans L1 arrest. 
  • Transgenerational Effects of Early Life Starvation on Growth, Reproduction, and Stress Resistance in Caenorhabditis elegans. 
  • Transgenerational Effects of Extended Dauer Diapause on Starvation Survival and Gene Expression Plasticity in Caenorhabditis elegans . 
  • Transient receptor potential vanilloid channels functioning in transduction of osmotic stimuli. 
  • Triggering a cell shape change by exploiting preexisting actomyosin contractions. 
  • UNC-6 (netrin) orients the invasive membrane of the anchor cell in C. elegans. 
  • UNC-6 (netrin) stabilizes oscillatory clustering of the UNC-40 (DCC) receptor to orient polarity 
  • Unlocking the secrets of the genome. 
  • Unwinding the Wnt action of casein kinase 1. 
  • Use of alternative assays to identify and prioritize organophosphorus flame retardants for potential developmental and neurotoxicity. 
  • Use of non-mammalian alternative models for neurotoxicological study. 
  • Using population selection and sequencing to characterize natural variation of starvation resistance in Caenorhabditis elegans . 
  • Viscera affectum anno: the gut beyond eating behaviours. 
  • Visualizing cytoplasmic ATP in C. elegans larvae using PercevalHR. 
  • Visualizing hidden heterogeneity in isogenic populations of C. elegans. 
  • Vitamin B12 Regulates Glial Migration and Synapse Formation through Isoform-Specific Control of PTP-3/LAR PRTP Expression. 
  • Wnt signalling shows its versatility. 
  • Xenobiotic metabolism and transport in Caenorhabditis elegans . 
  • Yersinia pestis kills Caenorhabditis elegans by a biofilm-independent process that involves novel virulence factors. 
  • ZTF-8 interacts with the 9-1-1 complex and is required for DNA damage response and double-strand break repair in the C. elegans germline. 
  • Zebrafish CYP1A expression in transgenic Caenorhabditis elegans protects from exposures to benzo[a]pyrene and a complex polycyclic aromatic hydrocarbon mixture. 
  • daf-16/FoxO promotes gluconeogenesis and trehalose synthesis during starvation to support survival. 
  • dbl-1/TGF-β and daf-12/NHR Signaling Mediate Cell-Nonautonomous Effects of daf-16/FOXO on Starvation-Induced Developmental Arrest 
  • ifet-1 is a broad-scale translational repressor required for normal P granule formation in C. elegans. 
  • t⁴ workshop report. Nanotoxicology: "the end of the beginning" - signs on the roadmap to a strategy for assuring the safe application and use of nanomaterials. 
  • α-Integrins dictate distinct modes of type IV collagen recruitment to basement membranes. 
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  Keywords of People

  • Baugh, L. Ryan, Associate Professor of Biology, Biology
  • Bennett, Vann, George Barth Geller Distinguished Professor of Molecular Biology, Duke Cancer Institute
  • Broverman, Sherryl A., Professor of the Practice of Biology, Biology
  • Hsu-Kim, Heileen, Professor in the Department of Civil and Environmental Engineering, Civil and Environmental Engineering
  • Morton, Kate, Student, Nicholas School of the Environment
  • Tsalik, Ephraim, Adjunct Associate Professor in the Department of Medicine, Medicine, Infectious Diseases