Rats, Wistar

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  Subject Areas on Research

  • A VGF-derived peptide attenuates development of type 2 diabetes via enhancement of islet β-cell survival and function. 
  • A blinded randomized assessment of laser Doppler flowmetry efficacy in standardizing outcome from intraluminal filament MCAO in the rat. 
  • A branched-chain amino acid-related metabolic signature that differentiates obese and lean humans and contributes to insulin resistance. 
  • A manganese porphyrin suppresses oxidative stress and extends the life span of streptozotocin-diabetic rats. 
  • A multicontrast MR atlas of the Wistar rat brain. 
  • A multidimensional magnetic resonance histology atlas of the Wistar rat brain. 
  • A polymorphism of the human matrix gamma-carboxyglutamic acid protein promoter alters binding of an activating protein-1 complex and is associated with altered transcription and serum levels. 
  • A precision 3D conformal treatment technique in rats: Application to whole-brain radiotherapy with hippocampal avoidance. 
  • A quantitative magnetic resonance histology atlas of postnatal rat brain development with regional estimates of growth and variability. 
  • A thermally responsive biopolymer for intra-articular drug delivery. 
  • Accumulation and endocrine disrupting effects of the flame retardant mixture Firemaster® 550 in rats: an exploratory assessment. 
  • Acetyl-L-carnitine deficiency as a cause of altered nerve myo-inositol content, Na,K-ATPase activity, and motor conduction velocity in the streptozotocin-diabetic rat. 
  • Activation of direct and indirect pathways of glycogen synthesis by hepatic overexpression of protein targeting to glycogen. 
  • Activation of the Nlrp3 inflammasome by mitochondrial reactive oxygen species: a novel mechanism of albumin-induced tubulointerstitial inflammation. 
  • Activation of transgene expression in skeletal muscle by focused ultrasound. 
  • Acute and Long-Term Effects of Brief Sevoflurane Anesthesia During the Early Postnatal Period in Rats. 
  • Adaptation to fat markedly increases pancreatic secretory response to intraduodenal fat in rats. 
  • Addressing cell-sourcing limitations with gene therapy. 
  • Adenovirus-mediated leptin expression normalises hypertension associated with diet-induced obesity. 
  • Adenovirus-mediated transfer of the muscle glycogen phosphorylase gene into hepatocytes confers altered regulation of glycogen metabolism. 
  • Age and sex differences in oxytocin and vasopressin V1a receptor binding densities in the rat brain: focus on the social decision-making network. 
  • An SOD mimic protects NADP+-dependent isocitrate dehydrogenase against oxidative inactivation. 
  • An amino-terminal fragment of LCRF, LCRF-(1-35), has the same activity as the natural peptide. 
  • An ontology-based segmentation scheme for tracking postnatal changes in the developing rodent brain with MRI. 
  • Androgens regulate prostate cancer cell growth via an AMPK-PGC-1α-mediated metabolic switch. 
  • Angiogenesis: an adaptive dynamic biological patterning problem. 
  • Angiotensin-converting enzyme inhibition prolongs survival and modifies the transition to heart failure in rats with pressure overload hypertrophy due to ascending aortic stenosis. 
  • Animal models in the research of abdominal aortic aneurysms development. 
  • Antiangiogenic agents protect liver sinusoidal lining cells from cold preservation injury in rat liver transplantation. 
  • Antibodies to the GABA(B) receptor in limbic encephalitis with seizures: case series and characterisation of the antigen. 
  • ApoE mimetic ameliorates motor deficit and tissue damage in rat spinal cord injury. 
  • Applications of a rat multiple tissue gene expression data set. 
  • Aprotinin improves functional outcome but not cerebral infarct size in an experimental model of stroke during cardiopulmonary bypass. 
  • Argon Inhalation for 24 Hours After Onset of Permanent Focal Cerebral Ischemia in Rats Provides Neuroprotection and Improves Neurologic Outcome. 
  • Assessment of pregnenolone effects on alcohol intake and preference in male alcohol preferring (P) rats. 
  • Baroreflex Impairment Precedes Cardiometabolic Dysfunction in an Experimental Model of Metabolic Syndrome: Role of Inflammation and Oxidative Stress. 
  • Baroreflex activation in conscious rats modulates the joint inflammatory response via sympathetic function. 
  • Baroreflex stimulation attenuates central but not peripheral inflammation in conscious endotoxemic rats. 
  • Baseline hippocampal theta oscillation speeds correlate with rate of operant task acquisition. 
  • Bioactivity of intraduodenally and intravenously infused fragments of luminal cholecystokinin releasing factor (LCRF). 
  • Brain Stimulation Differentially Modulates Nociception and Inflammation in Aversive and Non-aversive Behavioral Conditions. 
  • Brain injury and protective effects of hypothermia using triphenyltetrazolium chloride in neonatal rat. 
  • Branched-chain amino acids alter neurobehavioral function in rats. 
  • Bronchial and bronchiolar fibrosis in rats exposed to 2,3-pentanedione vapors: implications for bronchiolitis obliterans in humans. 
  • Burst-Dependent Bidirectional Plasticity in the Cerebellum Is Driven by Presynaptic NMDA Receptors. 
  • Bypassing the duodenum does not improve insulin resistance associated with diet-induced obesity in rodents. 
  • CNS inflammation and bone marrow neuropathy in type 1 diabetes. 
  • CRISPR/Cas9 Mediated Deletion of the Angiotensinogen Gene Reduces Hypertension: A Potential for Cure? 
  • Cafeteria diet is a robust model of human metabolic syndrome with liver and adipose inflammation: comparison to high-fat diet. 
  • Calpain inhibition prevents sinusoidal endothelial cell apoptosis in the cold ischemic rat liver. 
  • Calpain mediates ischemic injury of the liver through modulation of apoptosis and necrosis. 
  • Cardio-protective effects of carnitine in streptozotocin-induced diabetic rats. 
  • Carnitine insufficiency caused by aging and overnutrition compromises mitochondrial performance and metabolic control. 
  • Carotid sinus nerve electrical stimulation in conscious rats attenuates systemic inflammation via chemoreceptor activation. 
  • Cataract formation in a strain of rats selected for high oxidative stress. 
  • Cell-free hemoglobin reverses the endotoxin-mediated hyporesponsivity of rat aortic rings to alpha-adrenergic agents. 
  • Central angiotensin-(1-7) attenuates systemic inflammation via activation of sympathetic signaling in endotoxemic rats. 
  • Changes in superoxide dismutase and catalase activities of rat brain regions during early global transient ischemia/reperfusion. 
  • Changes in the production of IL-10 and TNF-alpha in skeletal muscle of rats with heart failure secondary to acute myocardial infarction. 
  • Characterization of ceramide synthesis. A dihydroceramide desaturase introduces the 4,5-trans-double bond of sphingosine at the level of dihydroceramide. 
  • Characterization of diffusing capacity and perfusion of the rat lung in a lipopolysaccaride disease model using hyperpolarized 129Xe. 
  • Cholinergic Stimulation Improves Oxidative Stress and Inflammation in Experimental Myocardial Infarction. 
  • Chronic N(G)-nitro-L-arginine methyl ester-induced hypertension : novel molecular adaptation to systolic load in absence of hypertrophy. 
  • Chronic aspiration of gastric fluid accelerates pulmonary allograft dysfunction in a rat model of lung transplantation. 
  • Chronic ethanol intoxication enhances the production of cytokine-induced neutrophil chemoattractant and macrophage inflammatory protein-2 by hepatocytes after human immunodeficiency virus-1 glycoprotein 120 vaccination. 
  • Cinacalcet ameliorates cardiac fibrosis in uremic hearts through suppression of endothelial-to-mesenchymal transition. 
  • Combination pharmacotherapy: a mixture of small doses of naltrexone, fluoxetine, and a thyrotropin-releasing hormone analogue reduces alcohol intake in three strains of alcohol-preferring rats. 
  • Comparison of the effects of propofol and pentobarbital on neurologic outcome and cerebral infarct size after temporary focal ischemia in the rat. 
  • Comparison of various iron chelators and prochelators as protective agents against cardiomyocyte oxidative injury. 
  • Complementary modulation of somatic inhibition by opioids and cannabinoids. 
  • Comprehensive analysis of tissue preservation and recording quality from chronic multielectrode implants. 
  • Consumption of a high-galactose diet induces diabetic-like changes in the inner ear. 
  • Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1. 
  • Correction of diet-induced hyperglycemia, hyperinsulinemia, and skeletal muscle insulin resistance by moderate hyperleptinemia. 
  • Cortical stimulation in conscious rats controls joint inflammation. 
  • Culture of primary rat hepatocytes within porous chitosan scaffolds. 
  • Cyclosporine increases local glomerular synthesis of reactive oxygen species in rats: effect of vitamin E on cyclosporine nephrotoxicity. 
  • D1 and D2 dopamine receptors stimulate hypothalamo-pituitary-adrenal activity in rats. 
  • Defective prolactin signaling impairs pancreatic β-cell development during the perinatal period. 
  • Delayed activation of spinal microglia contributes to the maintenance of bone cancer pain in female Wistar rats via P2X7 receptor and IL-18. 
  • Detection of Bladder Contractions From the Activity of the External Urethral Sphincter in Rats Using Sparse Regression. 
  • Development of lipophilic anticancer agents for the treatment of brain tumors by the esterification of water-soluble chlorambucil. 
  • Developmental expression of the glucose-dependent insulinotropic polypeptide gene in rat intestine. 
  • Diabetes-induced bradycardia is an intrinsic metabolic defect reversed by carnitine. 
  • Diabetic cardiomyopathy and carnitine deficiency. 
  • Diazepam, given postischemia, protects selectively vulnerable neurons in the rat hippocampus and striatum. 
  • Dietary regulation of catabolic disposal of 4-hydroxynonenal analogs in rat liver. 
  • Dietary regulation of glucose-dependent insulinotropic peptide (GIP) gene expression in rat small intestine. 
  • Differential and complementary effects of glucose and prolactin on islet DNA synthesis and gene expression. 
  • Differential effects of overexpressed glucokinase and hexokinase I in isolated islets. Evidence for functional segregation of the high and low Km enzymes. 
  • Differential effects of various fish proteins in altering body weight, adiposity, inflammatory status, and insulin sensitivity in high-fat-fed rats. 
  • Differential expression of S1 and elongation factor-1 alpha during rat development. 
  • Diffusion tensor magnetic resonance histology reveals microstructural changes in the developing rat brain. 
  • Direct antidiabetic effect of leptin through triglyceride depletion of tissues. 
  • Disappearance of body fat in normal rats induced by adenovirus-mediated leptin gene therapy. 
  • Discovery of LSZ102, a Potent, Orally Bioavailable Selective Estrogen Receptor Degrader (SERD) for the Treatment of Estrogen Receptor Positive Breast Cancer. 
  • Disinhibition in rat superior colliculus mediated by GABAc receptors. 
  • Distinct timing in the activity of cannabinoid-sensitive and cannabinoid-insensitive basket cells. 
  • Distinctive regulatory and metabolic properties of glycogen-targeting subunits of protein phosphatase-1 (PTG, GL, GM/RGl) expressed in hepatocytes. 
  • Distribution and function of cardiac angiotensin AT1- and AT2-receptor subtypes in hypertrophied rat hearts. 
  • Distribution and functional significance of cardiac angiotensin converting enzyme in hypertrophied rat hearts. 
  • Distribution of proteasomes and of the five proteolytic activities in rat tissues. 
  • Dopaminergic neurodegeneration induced by Parkinson's disease-linked G2019S LRRK2 is dependent on kinase and GTPase activity. 
  • Drug-induced reductions in ethanol intake in alcohol preferring and Fawn-Hooded rats. 
  • Dual contribution of TRPV4 antagonism in the regulatory effect of vasoinhibins on blood-retinal barrier permeability: diabetic milieu makes a difference. 
  • Duodenal-jejunal exclusion improves glucose tolerance in the diabetic, Goto-Kakizaki rat by a GLP-1 receptor-mediated mechanism. 
  • Early versus late repair of rotator cuff tears in rats. 
  • Editor's Highlight: Transplacental and Lactational Transfer of Firemaster® 550 Components in Dosed Wistar Rats. 
  • Effect of Multi Drug Resistance Protein 4 (MRP4) Inhibition on the Pharmacokinetics and Pharmacodynamics of Ciprofloxacin in Normal and Rats with LPS-Induced Inflammation. 
  • Effect of dietary protein manipulation on translocation of protein kinase C activity in various tissues of rats. 
  • Effect of potent redox-modulating manganese porphyrin, MnTM-2-PyP, on the Na(+)/H(+) exchangers NHE-1 and NHE-3 in the diabetic rat. 
  • Effects of Prenatal Exposure to a Mixture of Organophosphate Flame Retardants on Placental Gene Expression and Serotonergic Innervation in the Fetal Rat Brain. 
  • Effects of RSR13, a synthetic allosteric modifier of hemoglobin, alone and in combination with dizocilpine, on outcome from transient focal cerebral ischemia in the rat. 
  • Effects of ZD6169, a K ATP channel opener, on neurally-mediated plasma extravasation in the rat urinary bladder induced by chemical or electrical stimulation of nerves. 
  • Effects of a synthetic allosteric modifier of hemoglobin oxygen affinity on outcome from global cerebral ischemia in the rat. 
  • Effects of induced tolerance to bacterial lipopolysaccharide on myocardial infarct size in rats. 
  • Effects of intravesical prostaglandin E₂ on bladder function are preserved in capsaicin-desensitized rats. 
  • Effects of low doses of pioglitazone on resting-state functional connectivity in conscious rat brain. 
  • Effects of phentermine and phenformin on biomarkers of aging in rats. 
  • Effects of postischemic halothane administration on outcome from transient focal cerebral ischemia in the rat. 
  • Effects of titanium particle size on osteoblast functions in vitro and in vivo. 
  • Electroencephalographic burst suppression is not required to elicit maximal neuroprotection from pentobarbital in a rat model of focal cerebral ischemia. 
  • Endothelial cell and hepatocyte deaths occur by apoptosis after ischemia-reperfusion injury in the rat liver. 
  • Endurance training modulates lymphocyte function in rats with post-MI CHF. 
  • Evaluation of porcine-derived small intestine submucosa as a biodegradable graft for gastrointestinal healing. 
  • Evaluation of the role of nitric oxide in acid sensing ion channel mediated cell death. 
  • Evidence for a role of glucose-induced translocation of glucokinase in the control of hepatic glycogen synthesis. 
  • Exacerbation of systemic inflammation and increased cerebral infarct volume with cardiopulmonary bypass after focal cerebral ischemia in the rat. 
  • Excitation-contraction coupling in airway smooth muscle. 
  • Excitatory and inhibitory circuitry in the superficial gray layer of the superior colliculus. 
  • Exercise training changes IL-10/TNF-alpha ratio in the skeletal muscle of post-MI rats. 
  • Expression and function of transforming growth factor-β isoforms and cognate receptors in the rat urinary bladder following cyclophosphamide-induced cystitis. 
  • Expression and possible function of fibroblast growth factor 9 (FGF9) and its cognate receptors FGFR2 and FGFR3 in postnatal and adult retina. 
  • FGF14 regulates presynaptic Ca2+ channels and synaptic transmission. 
  • Fasting-induced hepatic production of DHEA is regulated by PGC-1alpha, ERRalpha, and HNF4alpha. 
  • Fatty acid amide hydrolase inhibition heightens anandamide signaling without producing reinforcing effects in primates. 
  • Fetal gene transfer with lentiviral vectors: long-term in vivo follow-up evaluation in a rat model. 
  • Fibrous glass and cancer. 
  • Five percent CO₂ is a potent, fast-acting inhalation anticonvulsant. 
  • Functional impairment in protein kinase C by RACK1 (receptor for activated C kinase 1) deficiency in aged rat brain cortex. 
  • Fundamental metabolic differences between hepatocytes and islet beta-cells revealed by glucokinase overexpression. 
  • Gait and behavior in an IL1β-mediated model of rat knee arthritis and effects of an IL1 antagonist. 
  • Gender differences in molecular remodeling in pressure overload hypertrophy. 
  • Gene expression in obliterative bronchiolitis-like lesions in 2,3-pentanedione-exposed rats. 
  • Glucocorticoid metabolism in proximal tubules modulates angiotensin II-induced electrolyte transport. 
  • Glucocorticoid-induced osteogenesis is negatively regulated by Runx2/Cbfa1 serine phosphorylation. 
  • Glucose 6-phosphate produced by glucokinase, but not hexokinase I, promotes the activation of hepatic glycogen synthase. 
  • Glucose down-regulates the expression of the peroxisome proliferator-activated receptor-alpha gene in the pancreatic beta -cell. 
  • Glucose-6-phosphatase overexpression lowers glucose 6-phosphate and inhibits glycogen synthesis and glycolysis in hepatocytes without affecting glucokinase translocation. Evidence against feedback inhibition of glucokinase. 
  • Glycine antagonism does not block ischemic spontaneous depolarization in the rat. 
  • Glycogen-targeting subunits and glucokinase differentially affect pathways of glycogen metabolism and their regulation in hepatocytes. 
  • Halothane reduces focal ischemic injury in the rat when brain temperature is controlled. 
  • Heart fatty acid binding protein as a marker for postmortem detection of early myocardial damage. 
  • Hemodilution during cardiopulmonary bypass increases cerebral infarct volume after middle cerebral artery occlusion in rats. 
  • Hepatic expression of a targeting subunit of protein phosphatase-1 in streptozotocin-diabetic rats reverses hyperglycemia and hyperphagia despite depressed glucokinase expression. 
  • Hepatic expression of malonyl-CoA decarboxylase reverses muscle, liver and whole-animal insulin resistance. 
  • Hepatic overexpression of glycerol-sn-3-phosphate acyltransferase 1 in rats causes insulin resistance. 
  • Heterogeneity in the phosphorylation of microtubule-associated protein MAP1B during rat brain development. 
  • High-frequency organization and synchrony of activity in the purkinje cell layer of the cerebellum. 
  • High-resolution imaging of progressive articular cartilage degeneration. 
  • Hyperglycemia induces insulin resistance on angiotensinogen gene expression in diabetic rat kidney proximal tubular cells. 
  • Hypertension is critically dependent on the carotid body input in the spontaneously hypertensive rat. 
  • Hypertrophic remodeling: gender differences in the early response to left ventricular pressure overload. 
  • Hypoxia of the growing liver accelerates regeneration. 
  • Identification of Dihydrofuro[3,4- d]pyrimidine Derivatives as Novel HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors with Promising Antiviral Activities and Desirable Physicochemical Properties. 
  • Identification of protein phosphatase-1-binding proteins by microcystin-biotin affinity chromatography. 
  • Immortalized rat proximal tubule cell lines expressing components of the renin-angiotensin system. 
  • Improved synthesis and metabolic stability analysis of the dopamine transporter ligand [(18)F]FECT. 
  • In vitro investigation of the hepatobiliary disposition mechanisms of the antifungal agent micafungin in humans and rats. 
  • In vivo models of cerebral ischemia: effects of parenterally administered NMDA receptor glycine site antagonists. 
  • In vivo profile of ICA-27243 [N-(6-chloro-pyridin-3-yl)-3,4-difluoro-benzamide], a potent and selective KCNQ2/Q3 (Kv7.2/Kv7.3) activator in rodent anticonvulsant models. 
  • Increased glucose disposal induced by adenovirus-mediated transfer of glucokinase to skeletal muscle in vivo. 
  • Induction of an antiinflammatory effect and prevention of cartilage damage in rat knee osteoarthritis by CF101 treatment. 
  • Induction of apoptotic cell death and prevention of tumor growth by ceramide analogues in metastatic human colon cancer. 
  • Induction of c-fos expression in the rostral medulla of rats following electroacupuncture stimulation. 
  • Induction of the ChREBPβ Isoform Is Essential for Glucose-Stimulated β-Cell Proliferation. 
  • Insulin Detemir Is Transported From Blood to Cerebrospinal Fluid and Has Prolonged Central Anorectic Action Relative to NPH Insulin. 
  • Insulin activates a novel adipocyte mitogen-activated protein kinase kinase kinase that shows rapid phasic kinetics and is distinct from c-Raf. 
  • Insulin and glucosamine infusions increase O-linked N-acetyl-glucosamine in skeletal muscle proteins in vivo. 
  • Insulin receptor substrate-1 (IRS-1) expression in rat brain. 
  • Interleukin-6 protects liver against warm ischemia/reperfusion injury and promotes hepatocyte proliferation in the rodent. 
  • Intracellular proteolytic cleavage of 9-cis-retinoic acid receptor alpha by cathepsin L-type protease is a potential mechanism for modulating thyroid hormone action. 
  • Intraischemic nitrous oxide alters neither neurologic nor histologic outcome: a comparison with dizocilpine. 
  • Intrathecal administration of a novel apoE-derived therapeutic peptide improves outcome following perinatal hypoxic-ischemic injury. 
  • Is early life body weight a predictor of longevity and tumor risk in rats? 
  • Isoflurane provides long-term protection against focal cerebral ischemia in the rat. 
  • JAK-STAT3 pathway regulates spinal astrocyte proliferation and neuropathic pain maintenance in rats. 
  • Ketamine potentiates oxidative stress and influences behavior and inflammation in response to lipolysaccharide (LPS) exposure in early life. 
  • Kv3.1b is a novel component of CNS nodes. 
  • LC-UV/MS methods for the analysis of prochelator-boronyl salicylaldehyde isonicotinoyl hydrazone (BSIH) and its active chelator salicylaldehyde isonicotinoyl hydrazone (SIH). 
  • Lack of evidence for a remote effect of renal ischemia/reperfusion acute kidney injury on outcome from temporary focal cerebral ischemia in the rat. 
  • Late administration of Mn porphyrin-based SOD mimic enhances diabetic complications. 
  • Lipoxin A4 inhibits microglial activation and reduces neuroinflammation and neuropathic pain after spinal cord hemisection. 
  • Long-Term Cognitive Deficits After Subarachnoid Hemorrhage in Rats. 
  • Long-term cognitive dysfunction following experimental subarachnoid hemorrhage: new perspectives. 
  • Long-term neuroprotection from a potent redox-modulating metalloporphyrin in the rat. 
  • Low-amplitude ultrasound enhances hydrodynamic-based gene delivery to rat kidney. 
  • Manganese porphyrin reduces retinal injury induced by ocular hypertension in rats. 
  • Matrix gla protein is regulated by a mechanism functionally related to the calcium-sensing receptor. 
  • Megalin/Cubulin-Lysosome-mediated Albumin Reabsorption Is Involved in the Tubular Cell Activation of NLRP3 Inflammasome and Tubulointerstitial Inflammation. 
  • Mesotheliomas induced in rats by the fibrous mineral erionite are independent from p53 alterations. 
  • Metabolic impact of adenovirus-mediated overexpression of the glucose-6-phosphatase catalytic subunit in hepatocytes. 
  • Modulation of experimental arthritis by vagal sensory and central brain stimulation. 
  • Molecular Mass-Dependent Resorption and Bone Regeneration of 3D Printed PPF Scaffolds in a Critical-Sized Rat Cranial Defect Model. 
  • Monitoring changes in gene expression in renal ischemia-reperfusion in the rat. 
  • Morphometric and electrical properties of reconstructed hippocampal CA3 neurons recorded in vivo. 
  • NMDA-glutamate receptors regulate phosphorylation of dendritic cytoskeletal proteins in the hippocampus. 
  • Neocortical disynaptic inhibition requires somatodendritic integration in interneurons. 
  • Neural control of urethral outlet activity in vivo: role of nitric oxide. 
  • Neuronal morphology generates high-frequency firing resonance. 
  • Neuroprotection from delayed postischemic administration of a metalloporphyrin catalytic antioxidant. 
  • Neuroprotective effect of NMDA receptor glycine recognition site antagonism persists when brain temperature is controlled. 
  • Neuroprotective effect of curcumin in an experimental rat model of subarachnoid hemorrhage. 
  • Neuroprotective efficacy from a lipophilic redox-modulating Mn(III) N-Hexylpyridylporphyrin, MnTnHex-2-PyP: rodent models of ischemic stroke and subarachnoid hemorrhage. 
  • Newly Developed Recombinant Antithrombin Protects the Endothelial Glycocalyx in an Endotoxin-Induced Rat Model of Sepsis. 
  • Nkx6.1 regulates islet β-cell proliferation via Nr4a1 and Nr4a3 nuclear receptors. 
  • Normal flux through ATP-citrate lyase or fatty acid synthase is not required for glucose-stimulated insulin secretion. 
  • OAB without an overactive bladder in the acute prostaglandin E2 rat model. 
  • Obesity and lipid stress inhibit carnitine acetyltransferase activity. 
  • Opioid receptor blockade prevents propofol-induced hypotension in rats. 
  • Overcompensation of CoA Trapping by Di(2-ethylhexyl) Phthalate (DEHP) Metabolites in Livers of Wistar Rats. 
  • Overexpression of annexin a1 induced by terephthalic acid calculi in rat bladder cancer. 
  • Overexpression of hexokinase I in isolated islets of Langerhans via recombinant adenovirus. Enhancement of glucose metabolism and insulin secretion at basal but not stimulatory glucose levels. 
  • Overexpression of rat long chain acyl-coa synthetase 1 alters fatty acid metabolism in rat primary hepatocytes. 
  • PBDEs Concentrate in the Fetal Portion of the Placenta: Implications for Thyroid Hormone Dysregulation. 
  • Pancreatic beta-cells in obesity. Evidence for induction of functional, morphologic, and metabolic abnormalities by increased long chain fatty acids. 
  • Pdx-1 activates islet α- and β-cell proliferation via a mechanism regulated by transient receptor potential cation channels 3 and 6 and extracellular signal-regulated kinases 1 and 2. 
  • Perinatal exposure to FireMaster® 550 (FM550), brominated or organophosphate flame retardants produces sex and compound specific effects on adult Wistar rat socioemotional behavior. 
  • Peroxisome proliferator-activated receptor-gamma co-activator 1alpha-mediated metabolic remodeling of skeletal myocytes mimics exercise training and reverses lipid-induced mitochondrial inefficiency. 
  • Perturbation of fuel homeostasis caused by overexpression of the glucose-6-phosphatase catalytic subunit in liver of normal rats. 
  • Pharmacological correction of hypothermic P(50) shift does not alter outcome from focal cerebral ischemia in rats. 
  • Pharmacological targeting of the mitochondrial phosphatase PTPMT1. 
  • Phosphorylation of the translational regulator, PHAS-I, by protein kinase CK2. 
  • Physiological mechanisms of sustained fumagillin-induced weight loss. 
  • Platelets induce sinusoidal endothelial cell apoptosis upon reperfusion of the cold ischemic rat liver. 
  • Pre-ischemic depletion of brain norepinephrine decreases infarct size in normothermic rats exposed to transient focal cerebral ischemia. 
  • Pressure overload induces greater hypertrophy and mortality in female mice with p38alpha MAPK inhibition. 
  • Prestress in the extracellular matrix sensitizes latent TGF-β1 for activation. 
  • Prolonged neuroinflammation after lipopolysaccharide exposure in aged rats. 
  • Protection of the endothelial glycocalyx by antithrombin in an endotoxin-induced rat model of sepsis. 
  • Protein kinase C activity, translocation, and conventional isoforms in aging rat brain. 
  • Purification and characterization of a luminal cholecystokinin-releasing factor from rat intestinal secretion. 
  • Radiolabelling of glucose-Tyr3-octreotate with 125I and analysis of its metabolism in rats: comparison with radiolabelled DOTA-Tyr3-octreotate. 
  • Rapid healing of femoral defects in rats with low dose sustained BMP2 expression from PEGDA hydrogel microspheres. 
  • Rat proximal tubule cell line transformed with origin-defective SV40 DNA: autocrine ANG II feedback. 
  • Redox activation of intracellular calcium release channels (ryanodine receptors) in the sustained phase of hypoxia-induced pulmonary vasoconstriction. 
  • Redox-Active Drug, MnTE-2-PyP5+, Prevents and Treats Cardiac Arrhythmias Preserving Heart Contractile Function. 
  • Reduction of spontaneous alcohol drinking and physical withdrawal by levemopamil, a novel Ca2+ channel antagonist, in rats. 
  • Reductive TCA cycle metabolism fuels glutamine- and glucose-stimulated insulin secretion. 
  • Regulation of islet beta-cell pyruvate metabolism: interactions of prolactin, glucose, and dexamethasone. 
  • Regulation of the macrophage population in postnatal rat testis. 
  • Relative neuroprotective effects of dizocilpine and isoflurane during focal cerebral ischemia in the rat. 
  • Reversal of diet-induced glucose intolerance by hepatic expression of a variant glycogen-targeting subunit of protein phosphatase-1. 
  • Robust age, but limited sex, differences in mu-opioid receptors in the rat brain: relevance for reward and drug-seeking behaviors in juveniles. 
  • Safety and Efficacy of Allogeneic Lung Spheroid Cells in a Mismatched Rat Model of Pulmonary Fibrosis. 
  • Segmental distribution of the endocytosis receptor gp330 in renal proximal tubules. 
  • Selective inhibition of eukaryotic translation initiation factor 2 alpha dephosphorylation potentiates fatty acid-induced endoplasmic reticulum stress and causes pancreatic beta-cell dysfunction and apoptosis. 
  • Semi-automated 3D segmentation of major tracts in the rat brain: comparing DTI with standard histological methods. 
  • Sensory pudendal nerve stimulation increases bladder capacity through sympathetic mechanisms in cyclophosphamide-induced cystitis rats. 
  • Serial echocardiographic-Doppler assessment of left ventricular geometry and function in rats with pressure-overload hypertrophy. Chronic angiotensin-converting enzyme inhibition attenuates the transition to heart failure. 
  • Serum Calprotectin as a Novel Biomarker in Abdominal Aortic Aneurysm Pathogenesis and Progression: Preliminary Data from Experimental Model in Rats. 
  • Sex Specific Placental Accumulation and Behavioral Effects of Developmental Firemaster 550 Exposure in Wistar Rats. 
  • Sex-Specific Effects of Progesterone on Early Outcome of Intracerebral Hemorrhage. 
  • Simvastatin treatment duration and cognitive preservation in experimental subarachnoid hemorrhage. 
  • Sparing effect of leptin on liver glycogen stores in rats during the fed-to-fasted transition. 
  • Stimulation of the sensory pudendal nerve increases bladder capacity in the rat. 
  • Studies on the preparation of chitosan microcarriers cross-linked by oxidized lactose and culture of primary hepatocytes. 
  • Study of gastric fluid induced cytokine and chemokine expression in airway smooth muscle cells and airway remodeling. 
  • Substrate specificities of g protein-coupled receptor kinase-2 and -3 at cardiac myocyte receptors provide basis for distinct roles in regulation of myocardial function. 
  • Sustained functional improvement by hepatocyte growth factor-like small molecule BB3 after focal cerebral ischemia in rats and mice. 
  • Synaptic plasticity rules with physiological calcium levels. 
  • Tetraethylammonium block of water flux in Aquaporin-1 channels expressed in kidney thin limbs of Henle's loop and a kidney-derived cell line. 
  • The BCKDH Kinase and Phosphatase Integrate BCAA and Lipid Metabolism via Regulation of ATP-Citrate Lyase. 
  • The constitutive secretory pathway is a major route for islet amyloid polypeptide secretion in neonatal but not adult rat islet cells. 
  • The effect of duodenal-jejunal bypass on glucose-dependent insulinotropic polypeptide secretion in Wistar rats. 
  • The effect of pro-inflammatory cytokines on the discharge rate of vagal nerve paraganglia in the rat. 
  • The inhibition of the kynurenine pathway prevents behavioral disturbances and oxidative stress in the brain of adult rats subjected to an animal model of schizophrenia. 
  • The novel, selective, brain-penetrant neuropeptide Y Y2 receptor antagonist, JNJ-31020028, tested in animal models of alcohol consumption, relapse, and anxiety. 
  • The role of AMPK and mTOR in nutrient sensing in pancreatic beta-cells. 
  • The role of bladder afferent pathways in bladder hyperactivity induced by the intravesical administration of nerve growth factor. 
  • The role of hyperthermia in regional alkylating agent chemotherapy. 
  • The role of pre-ischaemic application of the nitric oxide donor spermine/nitric oxide complex in enhancing flap survival in a rat model. 
  • The role of skeletal muscle in liver glutathione metabolism during acetaminophen overdose. 
  • The selective metabotropic glutamate receptor 7 allosteric agonist AMN082 inhibits inflammatory pain-induced and incision-induced hypersensitivity in rat. 
  • Thrittene, homologous with somatostatin-28((1-13)), is a novel peptide in mammalian gut and circulation. 
  • Tie2 expression and phosphorylation in angiogenic and quiescent adult tissues. 
  • Time-resolved optical tomography using short-pulse laser for tumor detection. 
  • Topical capsaicin treatment suppresses formalin-induced fos expression in rat spinal cord. 
  • Toxin injury-dependent switched expression between EF-1 alpha and its sister, S1, in rat skeletal muscle. 
  • Transcription factor decoy to study the molecular mechanism of negative regulation of renin gene expression in the liver in vivo. 
  • Transient focal cerebral ischemia induces a dramatic activation of small ubiquitin-like modifier conjugation. 
  • Treatment Planning and Delivery of Whole Brain Irradiation with Hippocampal Avoidance in Rats. 
  • Upregulation of osmo-mechanosensitive TRPV4 channel facilitates chronic hypoxia-induced myogenic tone and pulmonary hypertension. 
  • Validation of 19F-magnetic resonance determination of myocardial blood volume. 
  • Variable Pringle Maneuvers and Effect on Intestinal Epithelium in Rats. A Pilot Experimental Study in Rats. 
  • Verapamil suppresses d-amphetamine-induced place preference conditioning. 
  • Voiding behavior in awake unrestrained untethered spontaneously hypertensive and Wistar control rats. 
  • Wound contraction is attenuated by fasudil inhibition of Rho-associated kinase. 
  • Xenon neuroprotection in experimental stroke: interactions with hypothermia and intracerebral hemorrhage. 
  • Zymogen proteolysis within the pancreatic acinar cell is associated with cellular injury. 
  • [Bcl-2 and bax expression in rat cerebral ischemic preconditioning]. 
  • [Effects of intravenous anesthetics on LPS-induced production of tumour necrosis factor-alpha from primary cultures of rat glial cells in vitro]. 
  • [Electroacupuncture enhances enkephalin mRNA expression in the spinal cord and medulla, an in situ hybridization study]. 
  • [Induction of Fos-like protein in the rat spinal cord following electroacupuncture stimulation]. 
  • [Nphe1]nociceptin(1-13)-NH2 antagonizes nociceptin-induced hypotension, bradycardia, and hindquarters vasodilation in the anesthetized rat. 
  • beta-Endorphin-containing memory-cells and mu-opioid receptors undergo transport to peripheral inflamed tissue. 
  • beta-cell function in normal rats made chronically hyperleptinemic by adenovirus-leptin gene therapy. 
  • cGMP-independent inotropic effects of nitric oxide and peroxynitrite donors: potential role for nitrosylation. 
  • p38 MAP kinase inhibition enables proliferation of adult mammalian cardiomyocytes. 
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  Keywords of People

  • Chitneni, Satish K., Associate Professor in Radiology, Radiology
  • Driehuys, Bastiaan, Professor of Radiology, Biomedical Engineering
  • Freemark, Michael Scott, Robert C. Atkins, M.D. and Veronica Atkins Distinguished Professor of Pediatrics, in the School of Medicine, Pediatrics, Endocrinology
  • Gunn, Michael Dee, Professor of Medicine, Integrative Immunobiology
  • Laskowitz, Daniel Todd, Professor of Neurology, Duke Science & Society
  • McDonnell, Donald Patrick, Glaxo-Wellcome Distinguished Professor of Molecular Cancer Biology, in the School of Medicine, Cell Biology
  • Pitt, Geoffrey Stuart, Adjunct Professor in the Department of Medicine, Medicine, Cardiology
  • Yancy Jr., William Samuel, Professor of Medicine, Medicine, General Internal Medicine