Clinical Trials, Phase I as Topic
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Subject Areas on Research
- A genome-wide association study identifies susceptibility loci for ovarian cancer at 2q31 and 8q24.
- A hybrid Bayesian adaptive design for dose response trials.
- A pharmacogenetic study of aldehyde oxidase I in patients treated with XK469.
- A systematic review of randomized controlled trials for the prevention of bronchopulmonary dysplasia in infants.
- Absence of the wild-type allele predicts poor prognosis in adult de novo acute myeloid leukemia with normal cytogenetics and the internal tandem duplication of FLT3: a cancer and leukemia group B study.
- Adaptive clinical trial design.
- An exploration of relative health stock in advanced cancer patients.
- Andexanet alfa for the reversal of Factor Xa inhibitor related anticoagulation.
- Antiretroviral therapy: evaluating the new era in HIV treatment.
- CDX-1307: a novel vaccine under study as treatment for muscle-invasive bladder cancer.
- Cabozantinib in genitourinary malignancies.
- Clinical studies of angiogenesis inhibitors: the University of Texas MD Anderson Center Trial of Human Endostatin.
- Clinical uses of pegylated pharmaceuticals in oncology.
- Combining classification trees using MLE.
- Concurrent chemotherapy and intensity-modulated radiotherapy for organ preservation of locoregionally advanced oral cavity cancer.
- Development and utilization of a combined LC-UV and LC-MS/MS method for the simultaneous analysis of tegafur and 5-fluorouracil in human plasma to support a phase I clinical study of oral UFT®/leucovorin.
- Eptifibatide in percutaneous coronary intervention. A review.
- Evaluation and recommendations on good clinical laboratory practice guidelines for phase I-III clinical trials.
- Evaluation of ventricular arrhythmias in early clinical pharmacology trials and potential consequences for later development.
- Extending principles learned in model systems to clinical trials design.
- GNOSIS: guidelines for neuro-oncology: standards for investigational studies-reporting of phase 1 and phase 2 clinical trials.
- Genome-editing Technologies for Gene and Cell Therapy.
- HIV type 1 vaccine-induced cytotoxic T cell responses in phase I clinical trials: detection, characterization, and quantitation.
- HIV vaccines. Viral envelope fails to deliver?
- Impact of quality of life on patient expectations regarding phase I clinical trials.
- Informed consent in pediatric clinical trials.
- Inhibition of poxvirus growth by Terameprocol, a methylated derivative of nordihydroguaiaretic acid.
- Marketing drugs too early in testing.
- Modulation of the Coagulation Cascade Using Aptamers.
- Monoclonal antibodies for brain tumour treatment.
- Neoadjuvant therapy for pancreatic cancer: the Duke experience.
- P-glycoprotein (Pgp) modulation in untreated acute myeloid leukemia (AML): Cancer and Leukemia Group B (CALGB) trials in younger and older adults.
- PC-FACS.
- Patient expectations of benefit from phase I clinical trials: linguistic considerations in diagnosing a therapeutic misconception.
- Perceptions of patients and physicians regarding phase I cancer clinical trials: implications for physician-patient communication.
- Phase 1 clinical trials of the National Institutes of Health Vaccine Research Center HIV/AIDS candidate vaccines.
- Phase I participants' views of quality of life and trial participation burdens.
- Phase I studies with the novel nucleoside analog gemcitabine.
- Phase II study of the histone deacetylase inhibitor Romidepsin in relapsed small cell lung cancer (Cancer and Leukemia Group B 30304).
- Plasma Metabolites and Risk of Radiation-induced Esophagitis: A Secondary Analysis from a Prospective Study.
- Prasugrel, a third generation thienopyridine and potent platelet inhibitor.
- Prasugrel.
- Prevalence and impact of correlative science in breast cancer phase II trials.
- Production and quality control assessment of a GLP-grade immunotoxin, D2C7-(scdsFv)-PE38KDEL, for a phase I/II clinical trial.
- Quality of potent Mn porphyrin-based SOD mimics and peroxynitrite scavengers for pre-clinical mechanistic/therapeutic purposes.
- Rationale of technical requirements for NRG-BR001: The first NCI-sponsored trial of SBRT for the treatment of multiple metastases.
- Research participants' high expectations of benefit in early-phase oncology trials: are we asking the right question?
- Role of etoposide (VP-16) in preparatory regimens for patients with leukemia or lymphoma undergoing allogeneic bone marrow transplantation.
- Study of the media's potential influence on prospective research participants' understanding of and motivations for participation in a high-profile phase I trial.
- Successful Translation of Fluorescence Navigation During Oncologic Surgery: A Consensus Report.
- The correlation between patient characteristics and expectations of benefit from Phase I clinical trials.
- The role of amifostine as a radioprotector.
- Understanding of an aggregate probability statement by patients who are offered participation in Phase I clinical trials.
- Update of the international consensus on palliative radiotherapy endpoints for future clinical trials in bone metastases.
- Varieties of uncertainty and the validity of informed consent.
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Keywords of People
- Berchuck, Andrew, James M. Ingram Professor of Gynecologic Oncology, Obstetrics and Gynecology, Gynecologic Oncology
- Pang, Herbert, Adjunct Assistant Professor in the Department of Biostatistics and Bioinformatics, Biostatistics & Bioinformatics
- West, Vivian L, Clinical Associate in the School of Nursing, School of Nursing