Genes, Insect

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  Subject Areas on Research

  • A Drosophila CREB/CREM homolog encodes multiple isoforms, including a cyclic AMP-dependent protein kinase-responsive transcriptional activator and antagonist. 
  • A case study of the reproducibility of transcriptional reporter cell-based RNAi screens in Drosophila. 
  • A cell-specific nuclear receptor plays essential roles in adrenal and gonadal development. 
  • A large-scale functional approach to uncover human genes and pathways in Drosophila. 
  • A sodium channel mutation identified in Aedes aegypti selectively reduces cockroach sodium channel sensitivity to type I, but not type II pyrethroids. 
  • Abelson kinase (Abl) and RhoGEF2 regulate actin organization during cell constriction in Drosophila. 
  • Alternative splicing of an insect sodium channel gene generates pharmacologically distinct sodium channels. 
  • Alternative splicing of the BSC1 gene generates tissue-specific isoforms in the German cockroach. 
  • Analyses of promoter-proximal pausing by RNA polymerase II on the hsp70 heat shock gene promoter in a Drosophila nuclear extract. 
  • Armadillo coactivates transcription driven by the product of the Drosophila segment polarity gene dTCF. 
  • Association of misexpression with sterility in hybrids of Drosophila simulansand D. mauritiana. 
  • B56-associated protein phosphatase 2A is required for survival and protects from apoptosis in Drosophila melanogaster. 
  • Cell patterning in the Drosophila segment: engrailed and wingless antigen distributions in segment polarity mutant embryos. 
  • Characterization of cis-regulatory elements controlling repo transcription in Drosophila melanogaster. 
  • Chromosomal inversions and the reproductive isolation of species. 
  • Comparative genome sequencing of Drosophila pseudoobscura: chromosomal, gene, and cis-element evolution. 
  • Comprehensive analysis of the chromatin landscape in Drosophila melanogaster. 
  • Developmental evolution: how beetles evolved their shields. 
  • Differential requirements for segment polarity genes in wingless signaling. 
  • Drosophila APC2 is a cytoskeletally-associated protein that regulates wingless signaling in the embryonic epidermis. 
  • Drosophila betaHeavy-spectrin is essential for development and contributes to specific cell fates in the eye. 
  • Drosophila homologue of the Rothmund-Thomson syndrome gene: essential function in DNA replication during development. 
  • Drosophila stretchin-MLCK is a novel member of the Titin/Myosin light chain kinase family. 
  • Drosophila ultraspiracle modulates ecdysone receptor function via heterodimer formation. 
  • Evaluation of the interaction between insecticide resistance-associated genes and malaria transmission in Anopheles gambiae sensu lato in central Côte d'Ivoire. 
  • Evidence for a one-allele assortative mating locus. 
  • Evolution of a polyphenism by genetic accommodation. 
  • Evolution of genes and genomes on the Drosophila phylogeny. 
  • Evolution of the gene network underlying wing polyphenism in ants. 
  • Evolutionary adaptation of the amino acid and codon usage of the mosquito sodium channel following insecticide selection in the field mosquitoes. 
  • Evolutionary biology: Genes to make new species. 
  • FlyRNAi.org--the database of the Drosophila RNAi screening center: 2012 update. 
  • Focus on butterfly eyespot development. 
  • Forces for morphogenesis investigated with laser microsurgery and quantitative modeling. 
  • Functional analysis of the TAN-1 gene, a human homolog of Drosophila notch. 
  • Functional ecdysone receptor is the product of EcR and Ultraspiracle genes. 
  • Functional genomic analysis of phagocytosis and identification of a Drosophila receptor for E. coli. 
  • Gene expression divergence recapitulates the developmental hourglass model. 
  • Gene transposition as a cause of hybrid sterility in Drosophila. 
  • Genes on the wing. 
  • Genetics. Origin of species in overdrive. 
  • Genome annotation assessment in Drosophila melanogaster. 
  • Genome-wide patterns of expression in Drosophila pure species and hybrid males. II. Examination of multiple-species hybridizations, platforms, and life cycle stages. 
  • Heat-shock-specific phosphorylation and transcriptional activity of RNA polymerase II. 
  • Identification and characterization of a Drosophila nuclear receptor with the ability to inhibit the ecdysone response. 
  • Identification of co-regulated transcripts affecting male body size in Drosophila. 
  • Identification of functional elements and regulatory circuits by Drosophila modENCODE. 
  • Identifying a transcription factor interaction site on RNA polymerase II. 
  • Intraspecific Genetic Variation for Behavioral Isolation Loci in Drosophila. 
  • Large introns in relation to alternative splicing and gene evolution: a case study of Drosophila bruno-3. 
  • Mapping mutations in genes encoding the two large subunits of Drosophila RNA polymerase II defines domains essential for basic transcription functions and for proper expression of developmental genes. 
  • Mechanism of threshold size assessment: Metamorphosis is triggered by the TGF-beta/Activin ligand Myoglianin. 
  • Mechanisms for dominance: Adh heterodimer formation in heterozygotes between ENU or X-ray induced null alleles and normal alleles in Drosophila melanogaster. 
  • Molecular characterization of DSC1 orthologs in invertebrate species. 
  • Molecular organization and alternative splicing in zipper, the gene that encodes the Drosophila non-muscle myosin II heavy chain. 
  • Multilocus test for introgression between the cactophilic species Drosophila mojavensis and Drosophila arizonae. 
  • Multiple mutations and mutation combinations in the sodium channel of permethrin resistant mosquitoes, Culex quinquefasciatus. 
  • Mutations in the segment polarity genes wingless and porcupine impair secretion of the wingless protein. 
  • New neuroblast markers and the origin of the aCC/pCC neurons in the Drosophila central nervous system. 
  • Novel sodium channel gene mutations in Blattella germanica reduce the sensitivity of expressed channels to deltamethrin. 
  • PER protein interactions and temperature compensation of a circadian clock in Drosophila. 
  • Paleo-demography of the Drosophila melanogaster subgroup: application of the maximum likelihood method. 
  • Phosphorylation dependence of the initiation of productive transcription of Balbiani ring 2 genes in living cells. 
  • Polychaetoid is required to restrict segregation of sensory organ precursors from proneural clusters in Drosophila. 
  • Promoter prediction on a genomic scale--the Adh experience. 
  • RK2, a glial-specific homeodomain protein required for embryonic nerve cord condensation and viability in Drosophila. 
  • Rab11 helps maintain apical crumbs and adherens junctions in the Drosophila embryonic ectoderm. 
  • Reduced life span with heart and muscle dysfunction in Drosophila sarcoglycan mutants. 
  • Requirement for the vasa RNA helicase in gurken mRNA localization. 
  • Retina-specifically expressed novel subtypes of bovine cyclophilin. 
  • Retrotransposons Are the Major Contributors to the Expansion of the Drosophila ananassae Muller F Element. 
  • Segment polarity gene interactions modulate epidermal patterning in Drosophila embryos. 
  • Signaling activities of the Drosophila wingless gene are separately mutable and appear to be transduced at the cell surface. 
  • Signaling by wingless in Drosophila. 
  • SoxNeuro and Shavenbaby act cooperatively to shape denticles in the embryonic epidermis of Drosophila . 
  • Structure of the genes encoding transcription factor IIB and TATA box-binding protein from Drosophila melanogaster. 
  • The Drosophila Translational Control Element (TCE) is required for high-level transcription of many genes that are specifically expressed in testes. 
  • The Drosophila protein palmitoylome: characterizing palmitoyl-thioesterases and DHHC palmitoyl-transferases. 
  • The dishevelled protein is modified by wingless signaling in Drosophila. 
  • The fruitless gene is required for the proper formation of axonal tracts in the embryonic central nervous system of Drosophila. 
  • The nicotinic acetylcholine receptor gene family of the silkworm, Bombyx mori. 
  • The role of HOM-C genes in segmental transformations: reexamination of the Drosophila Sex combs reduced embryonic phenotype. 
  • The role of meiotic drive in hybrid male sterility. 
  • The segment polarity gene porcupine encodes a putative multitransmembrane protein involved in Wingless processing. 
  • Translocation of Y-linked genes to the dot chromosome in Drosophila pseudoobscura. 
  • Use of time-lapse imaging and dominant negative receptors to dissect the steroid receptor control of neuronal remodeling in Drosophila. 
  • mirror encodes a novel PBX-class homeoprotein that functions in the definition of the dorsal-ventral border in the Drosophila eye. 
  • optix Drives the Repeated Convergent Evolution of Butterfly Wing Pattern Mimicry 
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  Keywords of People

  • Bejsovec, Amy, Associate Professor of Biology, Biology
  • Erickson, Harold Paul, James B. Duke Distinguished Professor Emeritus, Cell Biology
  • Noor, Mohamed A. F., Professor of Biology, Duke University
  • Wray, Gregory Allan, Professor of Biology, Evolutionary Anthropology