Sequence Analysis, DNA

• 

  Subject Areas on Research

  • "Smart" DNA interfaces. 
  • 4.5 kb of the rat tyrosine hydroxylase 5' flanking sequence directs tissue specific expression during development and contains consensus sites for multiple transcription factors. 
  • A Bayesian network approach to operon prediction. 
  • A Flexible, Efficient Binomial Mixed Model for Identifying Differential DNA Methylation in Bisulfite Sequencing Data. 
  • A Fringe-modified Notch signal affects specification of mesoderm and endoderm in the sea urchin embryo. 
  • A Model Information Management Plan for Molecular Pathology Sequence Data Using Standards: From Sequencer to Electronic Health Record. 
  • A Nanopore Sequencing-Based Assay for Rapid Detection of Gene Fusions. 
  • A boy with fever and whorl keratopathy. 
  • A chemokine expressed in lymphoid high endothelial venules promotes the adhesion and chemotaxis of naive T lymphocytes. 
  • A cluster of HIV type 1 subtype C sequences from Ethiopia, observed in full genome analysis, is not sustained in subgenomic regions. 
  • A comparative study of gut microbiomes in captive nocturnal strepsirrhines. 
  • A comparison of the community diversity of foliar fungal endophytes between seedling and adult loblolly pines (Pinus taeda). 
  • A comprehensive iterative approach is highly effective in diagnosing individuals who are exome negative. 
  • A comprehensive structure-function analysis of Arabidopsis SNI1 defines essential regions and transcriptional repressor activity. 
  • A critical role of STAYGREEN/Mendel's I locus in controlling disease symptom development during Pseudomonas syringae pv tomato infection of Arabidopsis. 
  • A cross-sectional survey of Plasmodium falciparum pfcrt mutant haplotypes in the Democratic Republic of Congo. 
  • A gene on chromosome 11q23 coding for a putative glucose- 6-phosphate translocase is mutated in glycogen-storage disease types Ib and Ic. 
  • A genetic legacy of introgression confounds phylogeny and biogeography in oaks. 
  • A global meta-analysis of Tuber ITS rDNA sequences: species diversity, host associations and long-distance dispersal. 
  • A global reference for human genetic variation. 
  • A heterozygous IDH1R132H/WT mutation induces genome-wide alterations in DNA methylation. 
  • A high frequency of activating extracellular domain ERBB2 (HER2) mutation in micropapillary urothelial carcinoma. 
  • A high-resolution map of human evolutionary constraint using 29 mammals. 
  • A human protein related to yeast Cdc6p. 
  • A large kindred of early-onset osteoarthritis of the knee and hip: excluding the link to COL2A1 gene. 
  • A low-frequency variant at 8q24.21 is strongly associated with risk of oligodendroglial tumors and astrocytomas with IDH1 or IDH2 mutation. 
  • A maximum-likelihood base caller for DNA sequencing. 
  • A molecular phylogeny of the flagellated fungi (Chytridiomycota) and description of a new phylum (Blastocladiomycota). 
  • A molecular-based approach for examining responses of eukaryotes in microcosms to contaminant-spiked estuarine sediments. 
  • A mosaic analysis system with Cre or Tomato expression in the mouse. 
  • A multi-locus assessment of connectivity and historical demography in the bluehead wrasse (Thalassoma bifasciatum). 
  • A multi-locus molecular phylogeny of the Lepidoziaceae: laying the foundations for a stable classification. 
  • A multigene phylogenetic synthesis for the class Lecanoromycetes (Ascomycota): 1307 fungi representing 1139 infrageneric taxa, 317 genera and 66 families. 
  • A mutation in the TRPC6 cation channel causes familial focal segmental glomerulosclerosis. 
  • A new NOS2 promoter polymorphism associated with increased nitric oxide production and protection from severe malaria in Tanzanian and Kenyan children. 
  • A new kinesin tree. 
  • A novel 2-oxoacid-dependent dioxygenase involved in the formation of the goiterogenic 2-hydroxybut-3-enyl glucosinolate and generalist insect resistance in Arabidopsis,. 
  • A novel PCR-clamping assay reducing plant host DNA amplification significantly improves prokaryotic endo-microbiome community characterization. 
  • A novel alternative splice domain in zebrafish tenascin-C. 
  • A novel androgen-regulated gene, PMEPA1, located on chromosome 20q13 exhibits high level expression in prostate. 
  • A novel chloroplast gene reported for flagellate plants. 
  • A novel fibrotic disorder associated with increased dermal fibroblast proliferation and downregulation of genes of the microfibrillar network. 
  • A novel missense mutation of Wilms' Tumor 1 causes autosomal dominant FSGS. 
  • A novel, putative MEK kinase controls developmental timing and spatial patterning in Dictyostelium and is regulated by ubiquitin-mediated protein degradation. 
  • A nucleosome-guided map of transcription factor binding sites in yeast. 
  • A phylogeny of Adelanthaceae (Jungermanniales, Marchantiophyta) based on nuclear and chloroplast DNA markers, with comments on classification, cryptic speciation and biogeography. 
  • A polymorphism within the promoter of the TGFβ1 gene is associated with radiation sensitivity using an objective radiologic endpoint. 
  • A promoter sequence variant of ZNF750 is linked with familial psoriasis. 
  • A proteogenomic survey of the Medicago truncatula genome. 
  • A public resource facilitating clinical use of genomes. 
  • A strategy for the rapid identification of phosphorylation sites in the phosphoproteome. 
  • A systematic genetic assessment of 1,433 sequence variants of unknown clinical significance in the BRCA1 and BRCA2 breast cancer-predisposition genes. 
  • A targeted next-generation sequencing assay detects a high frequency of therapeutically targetable alterations in primary and metastatic breast cancers: implications for clinical practice. 
  • A taxonomic monograph of Ipomoea integrated across phylogenetic scales. 
  • A tiling-deletion-based genetic screen for cis-regulatory element identification in mammalian cells. 
  • A time and a place for everything: phylogenetic history and geography as joint predictors of oak plastome phylogeny. 
  • A toolkit for genetics providers in follow-up of patients with non-diagnostic exome sequencing. 
  • ADA Deficiency: Evaluation of the Clinical and Laboratory Features and the Outcome. 
  • Abscisic acid regulates root elongation through the activities of auxin and ethylene in Arabidopsis thaliana. 
  • Absence of mitochondrial progesterone receptor polymorphisms in women with spontaneous preterm birth. 
  • Absence of mutation in the beta- and gamma-synuclein genes in familial autosomal dominant Parkinson's disease. 
  • Abundance and genetic diversity of aerobic anoxygenic phototrophic bacteria of coastal regions of the pacific ocean. 
  • Actionable diagnosis of neuroleptospirosis by next-generation sequencing. 
  • Activated cAMP-response element-binding protein regulates neuronal expression of presenilin-1. 
  • Activation of the plant mitochondrial alternative oxidase: insights from site-directed mutagenesis. 
  • Additional evidence that PGAP1 loss of function causes autosomal recessive global developmental delay and encephalopathy. 
  • Adenine auxotrophic mutants of Aspergillus oryzae: development of a novel transformation system with triple auxotrophic hosts. 
  • Adenylate cyclase toxin (ACT) from Bordetella hinzii: characterization and differences from ACT of Bordetella pertussis. 
  • Advanced urothelial carcinoma: next-generation sequencing reveals diverse genomic alterations and targets of therapy. 
  • African strains of hepatitis E virus that are distinct from Asian strains. 
  • Allele-specific gene expression in a wild nonhuman primate population. 
  • Alleles of the yeast Pms1 mismatch-repair gene that differentially affect recombination- and replication-related processes. 
  • Allotetraploid Mimulus sookensis are highly interfertile despite independent origins. 
  • Alteration of the alkaloid profile in genetically modified tobacco reveals a role of methylenetetrahydrofolate reductase in nicotine N-demethylation. 
  • An Arabidopsis thaliana lipoxygenase gene can be induced by pathogens, abscisic acid, and methyl jasmonate. 
  • An STS-based map of the human genome. 
  • An alignment-free method to identify candidate orthologous enhancers in multiple Drosophila genomes. 
  • An autonomously self-assembling dendritic DNA nanostructure for target DNA detection. 
  • An efficient strategy of screening for pathogens in wild-caught ticks and mosquitoes by reusing small RNA deep sequencing data. 
  • An integrated genomic analysis of human glioblastoma multiforme. 
  • An obligately photosynthetic bacterial anaerobe from a deep-sea hydrothermal vent. 
  • Analyses of pediatric isolates of Cryptococcus neoformans from South Africa. 
  • Analysis of APOBEC-induced mutations in yeast strains with low levels of replicative DNA polymerases. 
  • Analysis of DNA methylation in a three-generation family reveals widespread genetic influence on epigenetic regulation. 
  • Analysis of association at single nucleotide polymorphisms in the APOE region. 
  • Analysis of erythropoietin and erythropoietin receptor genes expression in cattle during acute infection with Trypanosoma congolense. 
  • Analysis of homeobox gene HOXA10 mutations in cryptorchidism. 
  • Analysis of non-synonymous-coding variants of Parkinson's disease-related pathogenic and susceptibility genes in East Asian populations. 
  • Analysis of partial pol and env sequences indicates a high prevalence of HIV type 1 recombinant strains circulating in Gabon. 
  • Analysis of the indel at the ARMS2 3'UTR in age-related macular degeneration. 
  • Another surprise from the mitochondrial genome. 
  • Antiviral antibodies are necessary for control of simian immunodeficiency virus replication. 
  • Aquacultured rainbow trout (Oncorhynchus mykiss) possess a large core intestinal microbiota that is resistant to variation in diet and rearing density. 
  • Artifactual frame-shift p53 mutation at codon 249 detected with the Cyclist DNA sequencing method. 
  • Assessing disease severity in Pompe disease: the roles of a urinary glucose tetrasaccharide biomarker and imaging techniques. 
  • Association between 16S-23S internal transcribed spacer sequence groups of Mycobacterium avium complex and pulmonary disease. 
  • Association between novel PLCE1 variants identified in published esophageal cancer genome-wide association studies and risk of squamous cell carcinoma of the head and neck. 
  • Association of CD8(+) T lymphocyte repertoire spreading with the severity of DRESS syndrome. 
  • Association of Variants in BAG3 With Cardiomyopathy Outcomes in African American Individuals. 
  • Association of genetic variants of O6-methylguanine-DNA methyltransferase with risk of lung cancer in non-Hispanic Whites. 
  • Association of levels of fasting glucose and insulin with rare variants at the chromosome 11p11.2-MADD locus: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study. 
  • Association of low-frequency and rare coding-sequence variants with blood lipids and coronary heart disease in 56,000 whites and blacks. 
  • Association of misexpression with sterility in hybrids of Drosophila simulansand D. mauritiana. 
  • Associations between antibiotic exposure during pregnancy, birth weight and aberrant methylation at imprinted genes among offspring. 
  • Atractiella rhizophila, sp. nov., an endorrhizal fungus isolated from the Populus root microbiome. 
  • Authors' Reply. 
  • Automated constraint-based nucleotide sequence selection for DNA computation. 
  • Avian genomes. A flock of genomes. Introduction. 
  • BDNF Val66Met is associated with introversion and interacts with 5-HTTLPR to influence neuroticism. 
  • Bamboo Specialists from Two Mammalian Orders (Primates, Carnivora) Share a High Number of Low-Abundance Gut Microbes. 
  • Best practices and joint calling of the HumanExome BeadChip: the CHARGE Consortium. 
  • Binding site graphs: a new graph theoretical framework for prediction of transcription factor binding sites. 
  • Biogeography in deep time - What do phylogenetics, geology, and paleoclimate tell us about early platyrrhine evolution? 
  • Bisulfite pyrosequencing. 
  • Bisulfite sequencing of cloned alleles. 
  • Blood-based diagnostic testing for Pompe disease: consistency between GAA enzyme activity in dried blood spots and GAA gene sequencing results. 
  • Boranophosphates as mimics of natural phosphodiesters in DNA. 
  • Broad host range vectors for stable genomic library construction. 
  • Burkholderia glumae infection in an infant with chronic granulomatous disease. 
  • CA150, a nuclear protein associated with the RNA polymerase II holoenzyme, is involved in Tat-activated human immunodeficiency virus type 1 transcription. 
  • CCAAT/enhancer-binding protein alpha is required for transcription of the beta 3-adrenergic receptor gene during adipogenesis. 
  • CFTR haplotype analysis reveals genetic heterogeneity in the etiology of congenital bilateral aplasia of the vas deferens. 
  • CLN5 and CLN8 protein association with ceramide synthase: biochemical and proteomic approaches. 
  • CRISPR-Cas9 epigenome editing enables high-throughput screening for functional regulatory elements in the human genome. 
  • Calreticulin chaperones regulate functional expression of vomeronasal type 2 pheromone receptors. 
  • Candidate DNA repair susceptibility genes identified by exome sequencing in high-risk pancreatic cancer. 
  • Canine model and genomic structural organization of glycogen storage disease type Ia (GSD Ia). 
  • Capturing the primordial Kras mutation initiating urethane carcinogenesis. 
  • Carbonic anhydrase and CO2 sensing during Cryptococcus neoformans growth, differentiation, and virulence. 
  • Characterization of a cholesterol response element (CRE) in the promoter of the cholesteryl ester transfer protein gene: functional role of the transcription factors SREBP-1a, -2, and YY1. 
  • Characterization of a major cluster of nif, fix, and associated genes in a sugarcane endophyte, Acetobacter diazotrophicus. 
  • Characterization of hepatocellular adenoma and carcinoma using microRNA profiling and targeted gene sequencing. 
  • Characterization of immunophilins in the silkmoth Bombyx mori. 
  • Characterization of protective immune response elicited by a trimeric envelope protein from an Indian clade C HIV-1 isolate in rhesus macaques. 
  • Characterization of the Transmitted Virus in an Ongoing HIV-1 Epidemic Driven by Injecting Drug Use. 
  • Characterization of the interleukin 1 receptor-associated kinase 4 (IRAK4)-encoding gene in salmonid fish: the functional copy is rearranged in Oncorhynchus mykiss and that factor can impair TLR signaling in mammalian cells. 
  • Characterization of the intronic splicing silencers flanking FGFR2 exon IIIb. 
  • Characterization of the mouse transforming growth factor alpha gene: its expression during eyelid development and in waved 1 tissues. 
  • Characterization of the neural stem cell gene regulatory network identifies OLIG2 as a multifunctional regulator of self-renewal. 
  • Characterization of the rat type III hexokinase gene promoter. A functional octamer 1 motif is critical for basal promoter activity. 
  • Characterization of the variable-number tandem repeats in vrrA from different Bacillus anthracis isolates. 
  • Chromatin accessibility reveals insights into androgen receptor activation and transcriptional specificity. 
  • Chromosomal localization of gene for human glutamate receptor subunit-7. 
  • Circular viral DNA and anomalous junction sequence in PBMC of HIV-infected individuals with no detectable plasma HIV RNA. 
  • Circulating mutational portrait of cancer: manifestation of aggressive clonal events in both early and late stages. 
  • Clinical and environmental isolates of Cryptococcus gattii from Australia that retain sexual fecundity. 
  • Clinical application of exome sequencing in undiagnosed genetic conditions. 
  • Clinical experience with array CGH: case presentations from nine months of practice. 
  • Clinical interpretation and implications of whole-genome sequencing. 
  • Clonal amplification and maternal-infant transmission of nevirapine-resistant HIV-1 variants in breast milk following single-dose nevirapine prophylaxis. 
  • Clonal sequences recovered from plasma from patients with residual HIV-1 viremia and on intensified antiretroviral therapy are identical to replicating viral RNAs recovered from circulating resting CD4+ T cells. 
  • Cloning and characterization of a mammalian prenyl protein-specific protease. 
  • Cloning and characterization of two splice variants of human phosphodiesterase 11A. 
  • Cloning and sequence analysis of cnaA gene encoding the catalytic subunit of calcineurin from Aspergillus oryzae. 
  • Cloning of rat thymic stromal lymphopoietin receptor (TSLPR) and characterization of genomic structure of murine Tslpr gene. 
  • Cloning of the promoter region of human endoglin, the target gene for hereditary hemorrhagic telangiectasia type 1. 
  • Cloning, overexpression, purification, and immunobiology of an 85-kilodalton outer membrane protein from Haemophilus ducreyi. 
  • Coding Variation in ANGPTL4, LPL, and SVEP1 and the Risk of Coronary Disease. 
  • Community analysis reveals close affinities between endophytic and endolichenic fungi in mosses and lichens. 
  • Compact organization of rRNA genes in the filamentous fungus Ashbya gossypii. 
  • Comparative analyses of clinical and environmental populations of Cryptococcus neoformans in Botswana. 
  • Comparative evaluation of a new magnetic bead-based DNA extraction method from fecal samples for downstream next-generation 16S rRNA gene sequencing. 
  • Comparative evolutionary analysis of chalcone synthase and alcohol dehydrogenase loci in Arabidopsis, Arabis, and related genera (Brassicaceae). 
  • Comparative genome analysis of Trichophyton rubrum and related dermatophytes reveals candidate genes involved in infection. 
  • Comparative genome sequencing of Drosophila pseudoobscura: chromosomal, gene, and cis-element evolution. 
  • Comparative genomics and regulatory evolution: conservation and function of the Chs and Apetala3 promoters. 
  • Comparative genomics based on massive parallel transcriptome sequencing reveals patterns of substitution and selection across 10 bird species. 
  • Comparative genomics of Mortierella elongata and its bacterial endosymbiont Mycoavidus cysteinexigens. 
  • Comparative genomics reveals insights into avian genome evolution and adaptation. 
  • Comparative physical and transcript maps of approximately 1 Mb around loop-tail, a gene for severe neural tube defects on distal mouse chromosome 1 and human chromosome 1q22-q23. 
  • Comparative population structure of two deep-sea hydrothermal-vent-associated decapods (Chorocaris sp. 2 and Munidopsis lauensis) from southwestern Pacific back-arc basins. 
  • Comparative tests of evolutionary trade-offs in a palinurid lobster acoustic system. 
  • Comparison of ribosomal DNA ITS regions among geographic isolates of Cenococcum geophilum. 
  • Comparison of seven techniques for typing international epidemic strains of Clostridium difficile: restriction endonuclease analysis, pulsed-field gel electrophoresis, PCR-ribotyping, multilocus sequence typing, multilocus variable-number tandem-repeat analysis, amplified fragment length polymorphism, and surface layer protein A gene sequence typing. 
  • Comparison of viral Env proteins from acute and chronic infections with subtype C human immunodeficiency virus type 1 identifies differences in glycosylation and CCR5 utilization and suggests a new strategy for immunogen design. 
  • Comparisons of predicted genetic modules: identification of co-expressed genes through module gene flow. 
  • Complement factor H variant increases the risk of age-related macular degeneration. 
  • Complete genome sequencing and analysis of six enterovirus 71 strains with different clinical phenotypes. 
  • Complete genomic nucleotide sequence of the temperate bacteriophage Aa Phi 23 of Actinobacillus actinomycetemcomitans. 
  • Complexity reduction in context-dependent DNA substitution models. 
  • Comprehensive Genomic Profiling of Metastatic Tumors in a Phase 2 Biomarker Study of Everolimus in Advanced Renal Cell Carcinoma. 
  • Comprehensive, Integrative Genomic Analysis of Diffuse Lower-Grade Gliomas. 
  • Concessions of an alpha male? Cooperative defence and shared reproduction in multi-male primate groups. 
  • Consensus multi-locus sequence typing scheme for Cryptococcus neoformans and Cryptococcus gattii. 
  • Conservation of Endo16 expression in sea urchins despite evolutionary divergence in both cis and trans-acting components of transcriptional regulation. 
  • Conservation of Y-linked genes during human evolution revealed by comparative sequencing in chimpanzee. 
  • Conservation of the chitin utilization pathway in the Vibrionaceae. 
  • Considering the Benefits and Risks of Research Participants' Access to Sequence Data. 
  • Contrasting quaternary histories in an ecologically divergent sister pair of low-dispersing intertidal fish (Xiphister) revealed by multilocus DNA analysis. 
  • Contribution of RPB2 to multilocus phylogenetic studies of the euascomycetes (Pezizomycotina, Fungi) with special emphasis on the lichen-forming Acarosporaceae and evolution of polyspory. 
  • Contribution of horizontal gene transfer to the evolution of Saccharomyces cerevisiae. 
  • Cowpox virus contains two copies of an early gene encoding a soluble secreted form of the type II TNF receptor. 
  • Cross-reactive HIV-1-neutralizing human monoclonal antibodies identified from a patient with 2F5-like antibodies. 
  • Culture-based study of endophytes associated with rubber trees in Peru reveals a new class of Pezizomycotina: Xylonomycetes. 
  • Cyanobacterial ribosomal RNA genes with multiple, endonuclease-encoding group I introns. 
  • DAXX/ATRX, MEN1, and mTOR pathway genes are frequently altered in pancreatic neuroendocrine tumors. 
  • DNA Methylation and Susceptibility to Autism Spectrum Disorder. 
  • DNA Sequence Recognition by DNA Primase Using High-Throughput Primase Profiling. 
  • DNA copy number evolution in Drosophila cell lines. 
  • DNA global hypomethylation in squamous cell head and neck cancer associated with smoking, alcohol consumption and stage. 
  • DNA methylation alterations in response to pesticide exposure in vitro. 
  • DNA methylation at imprint regulatory regions in preterm birth and infection. 
  • DNA methylation of imprinted genes in Mexican-American newborn children with prenatal phthalate exposure. 
  • DNA methylation profiling in the Carolina Breast Cancer Study defines cancer subclasses differing in clinicopathologic characteristics and survival. 
  • DNA sequence and genetic characterization of plasmid pFQ11 from Frankia alni strain CpI1. 
  • DNA sequence characterization and molecular evolution of MAT1 and MAT2 mating-type loci of the self-compatible ascomycete mold Neosartorya fischeri. 
  • DNA sequencing: detecting methylation with force. 
  • DNMT3b polymorphism and hereditary nonpolyposis colorectal cancer age of onset. 
  • DNase I sensitivity QTLs are a major determinant of human expression variation. 
  • Data Harmonization for a Molecularly Driven Health System. 
  • Dating branches on the tree of life using DNA. 
  • De novo PacBio long-read and phased avian genome assemblies correct and add to reference genes generated with intermediate and short reads. 
  • De novo assembly using low-coverage short read sequence data from the rice pathogen Pseudomonas syringae pv. oryzae. 
  • De novo variants in the alternative exon 5 of SCN8A cause epileptic encephalopathy. 
  • Deciphering human immunodeficiency virus type 1 transmission and early envelope diversification by single-genome amplification and sequencing. 
  • Deciphering the model pathogenic fungus Cryptococcus neoformans. 
  • Decreased expression of lysyl hydroxylase 2 (LH2) in skin fibroblasts from three Ehlers-Danlos patients does not result from mutations in either the coding or proximal promoter region of the LH2 gene. 
  • Deep Sequencing of 71 Candidate Genes to Characterize Variation Associated with Alcohol Dependence. 
  • Deep divergence and rapid evolutionary rates in gut-associated Acetobacteraceae of ants. 
  • Depression in pregnancy, infant birth weight and DNA methylation of imprint regulatory elements. 
  • Destabilization of simple repetitive DNA sequences by transcription in yeast. 
  • Detailed analysis of allelic variation in the ABCA4 gene in age-related maculopathy. 
  • Detection of Donor's HIV Strain in HIV-Positive Kidney-Transplant Recipient. 
  • Detection of the JAK2 V617F mutation by LightCycler PCR and probe dissociation analysis. 
  • Development of an env gp41-based heteroduplex mobility assay for rapid human immunodeficiency virus type 1 subtyping. 
  • Different transcript patterns in response to specialist and generalist herbivores in the wild Arabidopsis relative Boechera divaricarpa. 
  • Differential DNA methylation with age displays both common and dynamic features across human tissues that are influenced by CpG landscape. 
  • Differential display of hepatic mRNA from killifish (Fundulus heteroclitus) inhabiting a Superfund estuary. 
  • Differential patterns of male and female mtDNA exchange across the Atlantic Ocean in the blue mussel, Mytilus edulis. 
  • Differentially methylated regions of imprinted genes in prenatal, perinatal and postnatal human tissues. 
  • Digging the New York City Skyline: soil fungal communities in green roofs and city parks. 
  • Digital microfluidic chips for chemical and biological applications. 
  • Distinct DNA methylation patterns characterize differentiated human embryonic stem cells and developing human fetal liver. 
  • Distinct Epigenetic Effects of Tobacco Smoking in Whole Blood and among Leukocyte Subtypes. 
  • Distinct microbial communities within the endosphere and rhizosphere of Populus deltoides roots across contrasting soil types. 
  • Distinguishing hypertrophic cardiomyopathy-associated mutations from background genetic noise. 
  • Distribution and diversity of planktonic fungi in the West Pacific Warm Pool. 
  • Distribution and phylogenetic significance of the 71-kb inversion in the plastid genome in Funariidae (Bryophyta). 
  • Distribution of WDR36 DNA sequence variants in patients with primary open-angle glaucoma. 
  • Distribution of optineurin sequence variations in an ethnically diverse population of low-tension glaucoma patients from the United States. 
  • Divergence dates for Malagasy lemurs estimated from multiple gene loci: geological and evolutionary context. 
  • Diversification before the most recent glaciation in Balanus glandula. 
  • Diversity and detection of nitrate assimilation genes in marine bacteria. 
  • Diversity and host range of foliar fungal endophytes: are tropical leaves biodiversity hotspots? 
  • Diversity and phylogenetic affinities of foliar fungal endophytes in loblolly pine inferred by culturing and environmental PCR. 
  • Diversity in the weapons of sexual selection: horn evolution in the beetle genus Onthophagus (Coleoptera: Scarabaeidae). 
  • Do asexual polyploid lineages lead short evolutionary lives? A case study from the fern genus Astrolepis. 
  • Dramatic mitochondrial gene rearrangements in the hermit crab Pagurus longicarpus (Crustacea, anomura). 
  • Droplet-based pyrosequencing using digital microfluidics. 
  • Drosophila ORC localizes to open chromatin and marks sites of cohesin complex loading. 
  • Dual infection with Ehrlichia chaffeensis and a spotted fever group rickettsia: a case report. 
  • Dynamic DNA methylation across diverse human cell lines and tissues. 
  • Early-onset stroke and vasculopathy associated with mutations in ADA2. 
  • Ectomycorrhizal fungal diversity in orchards of cultivated pecan (Carya illinoinensis; Juglandaceae). 
  • Effect of Genetic Diagnosis on Patients with Previously Undiagnosed Disease. 
  • Effects of inversions on within- and between-species recombination and divergence. 
  • Effects of premature termination codon polymorphisms in the Drosophila pseudoobscura subclade. 
  • Effects of raltegravir on 2-long terminal repeat circle junctions in HIV type 1 viremic and aviremic patients. 
  • Efficient Genome-Wide Sequencing and Low-Coverage Pedigree Analysis from Noninvasively Collected Samples. 
  • Elevated MAL expression is accompanied by promoter hypomethylation and platinum resistance in epithelial ovarian cancer. 
  • Emergence of Epidemic Dengue-1 Virus in the Southern Province of Sri Lanka. 
  • Empowering genomic medicine by establishing critical sequencing result data flows: the eMERGE example. 
  • Enhanced potency of a broadly neutralizing HIV-1 antibody in vitro improves protection against lentiviral infection in vivo. 
  • Enteropathy-associated T cell lymphoma subtypes are characterized by loss of function of SETD2. 
  • Epigenetic detection of human chromosome 14 uniparental disomy. 
  • Epigenetic regulation of AXL and risk of childhood asthma symptoms. 
  • Epstein-Barr Virus Genomes Reveal Population Structure and Type 1 Association with Endemic Burkitt Lymphoma. 
  • Essential light chain of Drosophila nonmuscle myosin II. 
  • Eurotiomycetes: Eurotiomycetidae and Chaetothyriomycetidae. 
  • Evaluation and optimisation of indel detection workflows for ion torrent sequencing of the BRCA1 and BRCA2 genes. 
  • Evaluation of 23S rRNA PCR primers for use in phylogenetic studies of bacterial diversity. 
  • Evaluation of Lipin 2 as a candidate gene for autosomal dominant 1 high-grade myopia. 
  • Evaluation of chromatin accessibility in prefrontal cortex of individuals with schizophrenia. 
  • Evaluation of the genomic extent of effects of fixed inversion differences on intraspecific variation and interspecific gene flow in Drosophila pseudoobscura and D. persimilis. 
  • Evidence against equimolarity of large repeat arrangements and a predominant master circle structure of the mitochondrial genome from a monkeyflower (Mimulus guttatus) lineage with cryptic CMS. 
  • Evidence for GC-biased gene conversion as a driver of between-lineage differences in avian base composition. 
  • Evidence for reciprocal origins in Polypodium hesperium (Polypodiaceae): a fern model system for investigating how multiple origins shape allopolyploid genomes. 
  • Evidence for sexuality in the opportunistic fungal pathogen Aspergillus fumigatus. 
  • Evidence from opsin genes rejects nocturnality in ancestral primates. 
  • Evidence of mRNA-mediated intron loss in the human-pathogenic fungus Cryptococcus neoformans. 
  • Evidence of sexual recombination among Cryptococcus neoformans serotype A isolates in sub-Saharan Africa. 
  • Evidence-ranked motif identification. 
  • Evolution of Pleopsidium (lichenized Ascomycota) S943 group I introns and the phylogeography of an intron-encoded putative homing endonuclease. 
  • Evolution of calcium-carbonate skeletons in the Hydractiniidae. 
  • Evolution of drug-resistant viral populations during interruption of antiretroviral therapy. 
  • Evolution of flux control in the glucosinolate pathway in Arabidopsis thaliana. 
  • Evolution of genes and genomes on the Drosophila phylogeny. 
  • Evolutionary analysis of the well characterized endo16 promoter reveals substantial variation within functional sites. 
  • Evolutionary relationships within the Neotropical, eusporangiate fern genus Danaea (Marattiaceae). 
  • Exaggerated CpH methylation in the autism-affected brain. 
  • Examination of type IV pilus expression and pilus-associated phenotypes in Kingella kingae clinical isolates. 
  • Exclusion of lumican and fibromodulin as candidate genes in MYP3 linked high grade myopia. 
  • Exome analysis of two limb-girdle muscular dystrophy families: mutations identified and challenges encountered. 
  • Exome sequencing followed by large-scale genotyping fails to identify single rare variants of large effect in idiopathic generalized epilepsy. 
  • Exome sequencing followed by large-scale genotyping suggests a limited role for moderately rare risk factors of strong effect in schizophrenia. 
  • Exome sequencing identifies distinct mutational patterns in liver fluke-related and non-infection-related bile duct cancers. 
  • Exome sequencing identifies highly recurrent MED12 somatic mutations in breast fibroadenoma. 
  • Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma. 
  • Exome sequencing in amyotrophic lateral sclerosis identifies risk genes and pathways. 
  • Exome sequencing of gastric adenocarcinoma identifies recurrent somatic mutations in cell adhesion and chromatin remodeling genes. 
  • Exome sequencing of liver fluke-associated cholangiocarcinoma. 
  • Exome-wide Sequencing Shows Low Mutation Rates and Identifies Novel Mutated Genes in Seminomas. 
  • Expansion of somatically reverted memory CD8+ T cells in patients with X-linked lymphoproliferative disease caused by selective pressure from Epstein-Barr virus. 
  • Expansion of the Stictidaceae by the addition of the saxicolous lichen-forming genus Ingvariella. 
  • Explicit DNase sequence bias modeling enables high-resolution transcription factor footprint detection. 
  • Expressed sequence tag analysis in Cycas, the most primitive living seed plant. 
  • Expression in aneuploid Drosophila S2 cells. 
  • Expression of a chemokine by ciliary body epithelium in horses with naturally occurring recurrent uveitis and in cultured ciliary body epithelial cells. 
  • Expression of the protein tyrosine phosphatase, phosphatase of regenerating liver 1, in the outer segments of primate cone photoreceptors. 
  • Expression profile of an androgen regulated prostate specific homeobox gene NKX3.1 in primary prostate cancer. 
  • Extending assembly of short DNA sequences to handle error. 
  • Extensive chloroplast haplotype variation indicates Pleistocene hybridization and radiation of North American Arabis drummondii, A. x divaricarpa, and A. holboellii (Brassicaceae). 
  • F-Seq: a feature density estimator for high-throughput sequence tags. 
  • FHIT and FRA3B 3p14.2 allele loss are common in lung cancer and preneoplastic bronchial lesions and are associated with cancer-related FHIT cDNA splicing aberrations. 
  • Factors associated with the diversification of the gut microbial communities within chimpanzees from Gombe National Park. 
  • Fanconi anemia gene variants in therapy-related myeloid neoplasms. 
  • Fast Dissemination of New HIV-1 CRF02/A1 Recombinants in Pakistan. 
  • Faster algorithms for optimal multiple sequence alignment based on pairwise comparisons. 
  • Finding regulatory DNA motifs using alignment-free evolutionary conservation information. 
  • Fine-scale variation in meiotic recombination in Mimulus inferred from population shotgun sequencing. 
  • Finishing the euchromatic sequence of the human genome. 
  • Flexible use of high-density oligonucleotide arrays for single-nucleotide polymorphism discovery and validation. 
  • Focused evolution of HIV-1 neutralizing antibodies revealed by structures and deep sequencing. 
  • Forced expression of AID facilitates the isolation of class switch variants from hybridoma cells. 
  • Formalizing morphologically cryptic biological entities: new insights from DNA taxonomy, hybridization, and biogeography in the leafy liverwort Porella platyphylla (Jungermanniopsida, Porellales). 
  • Forward genetic approaches in Chlamydia trachomatis. 
  • Frequent circumarctic and rare transequatorial dispersals in the lichenised agaric genus Lichenomphalia (Hygrophoraceae, Basidiomycota). 
  • Frequent detection of codon 877 mutation in the androgen receptor gene in advanced prostate cancers. 
  • Functional analysis of novel SNPs and mutations in human and mouse genomes. 
  • Functional and molecular characterization of human monoclonal antibody reactive with the immunodominant region of HIV type 1 glycoprotein 41. 
  • Functional consequences of natural sequence variation in the activation domain of HIV-1 Rev. 
  • Fungal community analysis by large-scale sequencing of environmental samples. 
  • Generating RNA Baits for Capture-Based Enrichment. 
  • Genetic Analysis of Complex Traits in Saccharomyces cerevisiae . 
  • Genetic analysis of the requirements for SOS induction by nalidixic acid in Escherichia coli. 
  • Genetic and 'cultural' similarity in wild chimpanzees. 
  • Genetic and functional association of FAM5C with myocardial infarction. 
  • Genetic and neutralization properties of subtype C human immunodeficiency virus type 1 molecular env clones from acute and early heterosexually acquired infections in Southern Africa. 
  • Genetic complexity in the replication-competent latent HIV reservoir increases with untreated infection duration in infected youth. 
  • Genetic diversity in the Mycobacterium tuberculosis complex based on variable numbers of tandem DNA repeats. 
  • Genetic diversity of the Cryptococcus species complex suggests that Cryptococcus gattii deserves to have varieties. 
  • Genetic diversity of the potentially therapeutic tapeworm Hymenolepis diminuta (Cestoda: Cyclophyllidea). 
  • Genetic isolation between two recently diverged populations of a symbiotic fungus. 
  • Genetic screen of African Americans with Fuchs endothelial corneal dystrophy. 
  • Genetic structure and genealogy in the Sphagnum subsecundum complex (Sphagnaceae: Bryophyta). 
  • Genetic typing of HIV-2 from a Senegalese/German heterosexual transmission. 
  • Genetic variability in beta-defensins is not associated with susceptibility to Staphylococcus aureus bacteremia. 
  • Genetic variation in the 3' non-coding region of dengue viruses. 
  • Genetic variation in the odorant receptor OR2J3 is associated with the ability to detect the "grassy" smelling odor, cis-3-hexen-1-ol. 
  • Genetic variation within and among populations of the threatened lichen Lobaria pulmonaria in Switzerland and implications for its conservation. 
  • Genome Evolution and Innovation across the Four Major Lineages of Cryptococcus gattii. 
  • Genome Sequencing of Arabidopsis abp1-5 Reveals Second-Site Mutations That May Affect Phenotypes. 
  • Genome engineering: the next genomic revolution. 
  • Genome sequence of the plant-pathogenic bacterium Dickeya dadantii 3937. 
  • Genome structure of a Saccharomyces cerevisiae strain widely used in bioethanol production. 
  • Genome wide analyses reveal little evidence for adaptive evolution in many plant species. 
  • Genome-wide mapping of DNase hypersensitive sites using massively parallel signature sequencing (MPSS). 
  • Genome-wide mutagenesis of influenza virus reveals unique plasticity of the hemagglutinin and NS1 proteins. 
  • Genome-wide prediction of imprinted murine genes. 
  • Genome-wide quantification of the effects of DNA methylation on human gene regulation. 
  • Genome-wide scan reveals signatures of selection related to pollution adaptation in non-model estuarine Atlantic killifish (Fundulus heteroclitus). 
  • Genome-wide specificity of DNA binding, gene regulation, and chromatin remodeling by TALE- and CRISPR/Cas9-based transcriptional activators. 
  • Genomes of Ashbya fungi isolated from insects reveal four mating-type loci, numerous translocations, lack of transposons, and distinct gene duplications. 
  • Genomewide investigation of adaptation to harmful algal blooms in common bottlenose dolphins (Tursiops truncatus). 
  • Genomic determination of the glucocorticoid response reveals unexpected mechanisms of gene regulation. 
  • Genomic insights into the atopic eczema-associated skin commensal yeast Malassezia sympodialis. 
  • Genomic organization, expression, and localization of murine Ran-binding protein 2 (RanBP2) gene. 
  • Genomic signatures of near-extinction and rebirth of the crested ibis and other endangered bird species. 
  • Genomic structure and embryonic expression of estrogen receptor beta a (ERbetaa) in zebrafish (Danio rerio). 
  • Genomic structure and organization of the high grade Myopia-2 locus (MYP2) critical region: mutation screening of 9 positional candidate genes. 
  • Genomic sweeping for hypermethylated genes. 
  • Genomics and Transcriptomics Analyses of the Oil-Accumulating Basidiomycete Yeast Trichosporon oleaginosus: Insights into Substrate Utilization and Alternative Evolutionary Trajectories of Fungal Mating Systems. 
  • Genomics and genetics of human and primate y chromosomes. 
  • Genotypic analysis of tumor suppressor genes PTEN/MMAC1 and p53 in head and neck squamous cell carcinomas. 
  • Genotypic diversity of anaerobic isolates from bloodstream infections. 
  • Genotypic diversity of coagulase-negative staphylococci causing endocarditis: a global perspective. 
  • Geographic selection in the small heat shock gene complex differentiating populations of Drosophila pseudoobscura. 
  • Germline Genetic IKZF1 Variation and Predisposition to Childhood Acute Lymphoblastic Leukemia. 
  • Germline Mutations in ATM and BRCA1/2 Distinguish Risk for Lethal and Indolent Prostate Cancer and are Associated with Early Age at Death. 
  • Germline and somatic SMARCA4 mutations characterize small cell carcinoma of the ovary, hypercalcemic type. 
  • Germline mutations in HOXB13 and prostate-cancer risk. 
  • Germline mutations in glial cell line-derived neurotrophic factor (GDNF) and RET in a Hirschsprung disease patient. 
  • Giant deep-sea protist produces bilaterian-like traces. 
  • Global analysis of genomic instability caused by DNA replication stress in Saccharomyces cerevisiae. 
  • Global analysis of the evolution and mechanism of echinocandin resistance in Candida glabrata. 
  • Global genetic diversity of human metapneumovirus fusion gene. 
  • Global patterns in peatmoss biodiversity. 
  • Glycogen-branching enzyme deficiency leads to abnormal cardiac development: novel insights into glycogen storage disease IV. 
  • Group-I intron family in the nuclear ribosomal RNA small subunit genes of Cenococcum geophilum isolates. 
  • HBV whole-genome mutation profile in HIV-1/HBV coinfected patients in a long-term follow-up study. 
  • HIV Resistance and Prevention of Mother-to-Child Transmission Regimen in HIV-Infected Infants in Northern Tanzania. 
  • HIV Transmission Patterns Among Immigrant Latinos Illuminated by the Integration of Phylogenetic and Migration Data. 
  • HIV quasispecies and resampling. 
  • HIV type 1 from a patient with baseline resistance to CCR5 antagonists uses drug-bound receptor for entry. 
  • Harmonizing Clinical Sequencing and Interpretation for the eMERGE III Network. 
  • Helicobacter canis bacteremia in a patient with fever of unknown origin. 
  • Heritable individual-specific and allele-specific chromatin signatures in humans. 
  • Heterochromatic sequences in a Drosophila whole-genome shotgun assembly. 
  • Heterogeneous polymerase fidelity and mismatch repair bias genome variation and composition. 
  • Heterothallic mating in Mucor irregularis and first isolate of the species outside of Asia. 
  • High diversity and widespread occurrence of mitotic spore mats in ectomycorrhizal Pezizales. 
  • High frequency of mutations of the PIK3CA gene in human cancers. 
  • High genetic diversity and population differentiation in Boechera fecunda, a rare relative of Arabidopsis. 
  • High throughput detection of M6P/IGF2R intronic hypermethylation and LOH in ovarian cancer. 
  • High-Throughput Mapping of B Cell Receptor Sequences to Antigen Specificity. 
  • High-resolution mapping and characterization of open chromatin across the genome. 
  • Highly active zinc-finger nucleases by extended modular assembly. 
  • Historical effects on beta diversity and community assembly in Amazonian trees. 
  • History and evolution of alpine plants endemic to the Qinghai-Tibetan Plateau: Aconitum gymnandrum (Ranunculaceae). 
  • Host lifestyle affects human microbiota on daily timescales. 
  • Host-symbiont stability and fast evolutionary rates in an ant-bacterium association: cospeciation of camponotus species and their endosymbionts, candidatus blochmannia. 
  • Human GFRA1: cloning, mapping, genomic structure, and evaluation as a candidate gene for Hirschsprung disease susceptibility. 
  • Human and mouse alpha-synuclein genes: comparative genomic sequence analysis and identification of a novel gene regulatory element. 
  • Human cardiac cis-regulatory elements, their cognate transcription factors, and regulatory DNA sequence variants. 
  • Human disturbance causes the formation of a hybrid swarm between two naturally sympatric fish species. 
  • Human genomic regions with exceptionally high levels of population differentiation identified from 911 whole-genome sequences. 
  • Human glycogen debranching enzyme gene (AGL): complete structural organization and characterization of the 5' flanking region. 
  • Human immunodeficiency virus type 1 protease genotype predicts immune and viral responses to combination therapy with protease inhibitors (PIs) in PI-naive patients. 
  • Human metapneumovirus, Peru. 
  • Human promoters are intrinsically directional. 
  • Human syndromes of immunodeficiency and dysregulation are characterized by distinct defects in T-cell receptor repertoire development. 
  • Hybrid de novo genome assembly and centromere characterization of the gray mouse lemur (Microcebus murinus). 
  • IGF2R genetic variants, circulating IGF2 concentrations and colon cancer risk in African Americans and Whites. 
  • Identification and characterization of K12 (SECTM1), a novel human gene that encodes a Golgi-associated protein with transmembrane and secreted isoforms. 
  • Identification and characterization of a Drosophila nuclear receptor with the ability to inhibit the ecdysone response. 
  • Identification and characterization of a cDNA encoding cytochrome P450 3A from the fresh water teleost medaka (Oryzias latipes). 
  • Identification and characterization of cell type-specific and ubiquitous chromatin regulatory structures in the human genome. 
  • Identification and characterization of the human parkin gene promoter. 
  • Identification and developmental expression of two activin receptors in baboon lung. 
  • Identification of HIV-1 genitourinary tract compartmentalization by analyzing the env gene sequences in urine. 
  • Identification of a putative Salmonella enterica serotype typhimurium host range factor with homology to IpaH and YopM by signature-tagged mutagenesis. 
  • Identification of a region of genetic variability among Bacillus anthracis strains and related species. 
  • Identification of a regulated alkaline phosphatase, a cell surface-associated lipoprotein, in Mycobacterium smegmatis. 
  • Identification of amino acid substitutions associated with neutralization phenotype in the human immunodeficiency virus type-1 subtype C gp120. 
  • Identification of asteroid genera with species capable of larval cloning. 
  • Identification of core promoter modules in Drosophila and their application in accurate transcription start site prediction. 
  • Identification of differentially methylated genes in normal prostate tissues from African American and Caucasian men. 
  • Identification of driver genes in hepatocellular carcinoma by exome sequencing. 
  • Identification of fungi associated with municipal compost using DNA-based techniques. 
  • Identification of genes expressed in a human scleral cDNA library. 
  • Identification of new mamu-DRB alleles using DGGE and direct sequencing. 
  • Identification of ongoing human immunodeficiency virus type 1 (HIV-1) replication in residual viremia during recombinant HIV-1 poxvirus immunizations in patients with clinically undetectable viral loads on durable suppressive highly active antiretroviral therapy. 
  • Identification of recurrent USP48 and BRAF mutations in Cushing's disease. 
  • Identification of the mating-type (MAT) locus that controls sexual reproduction of Blastomyces dermatitidis. 
  • Identification of the sequences within the human complement 3 promoter required for estrogen responsiveness provides insight into the mechanism of tamoxifen mixed agonist activity. 
  • Identification of variants in CNGA3 as cause for achromatopsia by exome sequencing of a single patient. 
  • Identifying branch-specific positive selection throughout the regulatory genome using an appropriate proxy neutral. 
  • Identifying gene expression from single cells to single genes. 
  • Identifying multiple origins of polyploid taxa: a multilocus study of the hybrid cloak fern (Astrolepis integerrima; Pteridaceae). 
  • Immunization with recombinant HLA classes I and II, HIV-1 gp140, and SIV p27 elicits protection against heterologous SHIV infection in rhesus macaques. 
  • Impact of genotypic resistance testing on physician selection of antiretroviral therapy. 
  • Implementing a cumulative supermatrix approach for a comprehensive phylogenetic study of the Teloschistales (Pezizomycotina, Ascomycota). 
  • Importance sampling for the infinite sites model. 
  • Imprinted expression of the canine IGF2R, in the absence of an anti-sense transcript or promoter methylation. 
  • Imprinting of PEG3, the human homologue of a mouse gene involved in nurturing behavior. 
  • In-depth analysis of Kaposi's sarcoma-associated herpesvirus microRNA expression provides insights into the mammalian microRNA-processing machinery. 
  • Inbreeding depression in non-human primates: a historical review of methods used and empirical data. 
  • Increased rectal microbial richness is associated with the presence of colorectal adenomas in humans. 
  • Increased risk of low birth weight in women with placental malaria associated with P. falciparum VAR2CSA clade. 
  • Independent ancient polyploidy events in the sister families Brassicaceae and Cleomaceae. 
  • Indole-3-acetic acid biosynthesis is deficient in Gluconacetobacter diazotrophicus strains with mutations in cytochrome c biogenesis genes. 
  • Inferring fetal fractions from read heterozygosity empowers the noninvasive prenatal screening. 
  • Informative priors based on transcription factor structural class improve de novo motif discovery. 
  • Informative priors on fetal fraction increase power of the noninvasive prenatal screen. 
  • Inhibition of a yeast LTR retrotransposon by human APOBEC3 cytidine deaminases. 
  • Initial antibodies binding to HIV-1 gp41 in acutely infected subjects are polyreactive and highly mutated. 
  • Initial sequencing and analysis of the human genome. 
  • Initial sequencing and comparative analysis of the mouse genome. 
  • Insensitivity of Diverse and Temporally Variable Particle-Associated Microbial Communities to Bulk Seawater Environmental Parameters. 
  • Integrated RNA and DNA sequencing reveals early drivers of metastatic breast cancer. 
  • Integrating chemical mutagenesis and whole-genome sequencing as a platform for forward and reverse genetic analysis of Chlamydia. 
  • Integration of Contact Tracing and Phylogenetics in an Investigation of Acute HIV Infection. 
  • Interactive or static reports to guide clinical interpretation of cancer genomics. 
  • Interrogation of individual intratumoral B lymphocytes from lung cancer patients for molecular target discovery. 
  • Intraspecific phylogenetic congruence among multiple symbiont genomes. 
  • Intraspecific variation in symbiont genomes: bottlenecks and the aphid-buchnera association. 
  • Invasive Curvularia Infection in Pediatric Patients With Hematologic Malignancy Identified by Fungal Sequencing. 
  • Invasive disease caused by nontuberculous mycobacteria, Tanzania. 
  • Investigating deep phylogenetic relationships among cyanobacteria and plastids by small subunit rRNA sequence analysis. 
  • Involvement of two putative alternative sigma factors in stress response of the radioresistant bacterium Deinococcus radiodurans. 
  • Is MMTV associated with human breast cancer? Maybe, but probably not. 
  • Is local adaptation in Mimulus guttatus caused by trade-offs at individual loci? 
  • Is the aneuploid chromosome in an apomictic Boechera holboellii a genuine B chromosome? 
  • Isolation and characterization of a new chemokine receptor gene, the putative chicken CXCR1. 
  • Isolation and characterization of the CYP71D16 trichome-specific promoter from Nicotiana tabacum L. 
  • Isolation and initial characterization of the 5' flanking region of the human and murine cyclic guanosine monophosphate-phosphodiesterase beta-subunit genes. 
  • Isolation and initial characterization of the BRCA2 promoter. 
  • Isolation and nucleotide sequence of human liver glycogen debranching enzyme mRNA: identification of multiple tissue-specific isoforms. 
  • Lack of association of mutations in optineurin with disease in patients with adult-onset primary open-angle glaucoma. 
  • Lactobacillus reuteri DSM 20016 produces cobalamin-dependent diol dehydratase in metabolosomes and metabolizes 1,2-propanediol by disproportionation. 
  • Landscape position influences microbial composition and function via redistribution of soil water across a watershed. 
  • Large introns in relation to alternative splicing and gene evolution: a case study of Drosophila bruno-3. 
  • Large scale association analysis for identification of genes underlying premature coronary heart disease: cumulative perspective from analysis of 111 candidate genes. 
  • Large-scale identification and analysis of genome-wide single-nucleotide polymorphisms for mapping in Arabidopsis thaliana. 
  • Large-scale identification, mapping, and genotyping of single-nucleotide polymorphisms in the human genome. 
  • Leptotrichia endocarditis: report of two cases from the International Collaboration on Endocarditis (ICE) database and review of previous cases. 
  • Leuconostoc bacteremia in pediatric patients with short bowel syndrome: case series and review. 
  • Life, diversity and the pursuit of haplotypes. 
  • LigAmp for sensitive detection of single-nucleotide differences. 
  • Living related versus deceased donor liver transplantation for maple syrup urine disease. 
  • Local replication of simian immunodeficiency virus in the breast milk compartment of chronically-infected, lactating rhesus monkeys. 
  • Low frequency of paleoviral infiltration across the avian phylogeny. 
  • Low level exposure to the flame retardant BDE-209 reduces thyroid hormone levels and disrupts thyroid signaling in fathead minnows. 
  • Low prevalence of Pneumocystis pneumonia (PCP) but high prevalence of pneumocystis dihydropteroate synthase (dhps) gene mutations in HIV-infected persons in Uganda. 
  • Low prevalence of myocilin mutations in an African American population with primary open-angle glaucoma. 
  • Lysis and lysis inhibition in bacteriophage T4: rV mutations reside in the holin t gene. 
  • MPDA: microarray pooled DNA analyzer. 
  • MSIseq: Software for Assessing Microsatellite Instability from Catalogs of Somatic Mutations. 
  • MTL genotypes, phenotypic switching, and susceptibility profiles of Candida parapsilosis species group compared to Lodderomyces elongisporus. 
  • Major clades of Agaricales: a multilocus phylogenetic overview. 
  • Making sense of microarrays. 
  • Malaria severity and human nitric oxide synthase type 2 (NOS2) promoter haplotypes. 
  • Mammalian dwarfins are phosphorylated in response to transforming growth factor beta and are implicated in control of cell growth. 
  • Mass spectrometry of nucleic acids: the promise of matrix-assisted laser desorption-ionization (MALDI) mass spectrometry. 
  • Maternal microchimerism in Hirschsprung's disease. 
  • Mating-type locus of Cryptococcus neoformans: a step in the evolution of sex chromosomes. 
  • Matrix metalloproteinase-1 gene promoter polymorphism and risk of ovarian cancer. 
  • Maximizing ecological and evolutionary insight in bisulfite sequencing data sets. 
  • Measures of linkage disequilibrium among neighbouring SNPs indicate asymmetries across the house mouse hybrid zone. 
  • Measuring spatial preferences at fine-scale resolution identifies known and novel cis-regulatory element candidates and functional motif-pair relationships. 
  • Mechanisms for dominance: Adh heterodimer formation in heterozygotes between ENU or X-ray induced null alleles and normal alleles in Drosophila melanogaster. 
  • Medical oncologists' perspectives of the Veterans Affairs National Precision Oncology Program. 
  • Mesotheliomas induced in rats by the fibrous mineral erionite are independent from p53 alterations. 
  • Methodology for a vaginal and urinary microbiome study in women with mixed urinary incontinence. 
  • Microbiome of the upper troposphere: species composition and prevalence, effects of tropical storms, and atmospheric implications. 
  • Microsatellite analysis of genetic diversity among clinical and nonclinical Saccharomyces cerevisiae isolates suggests heterozygote advantage in clinical environments. 
  • Misidentification of Neosartorya pseudofischeri as Aspergillus fumigatus in a lung transplant patient. 
  • Mismatch repair proteins regulate heteroduplex formation during mitotic recombination in yeast. 
  • Missing genetic risk in neural tube defects: can exome sequencing yield an insight? 
  • Mistaken Identity: Another Bias in the Use of Relative Genetic Divergence Measures for Detecting Interspecies Introgression. 
  • Mitochondrial DNA sequence variation associated with dementia and cognitive function in the elderly. 
  • Mitochondrial NADP(H) deficiency due to a mutation in NADK2 causes dienoyl-CoA reductase deficiency with hyperlysinemia. 
  • Mitochondrial gene rearrangements confirm the parallel evolution of the crab-like form. 
  • Mobile elements and mitochondrial genome expansion in the soil fungus and potato pathogen Rhizoctonia solani AG-3. 
  • Modeling the evolution of regulatory elements by simultaneous detection and alignment with phylogenetic pair HMMs. 
  • Molecular analyses of the Arabidopsis TUBBY-like protein gene family. 
  • Molecular analysis of HLA-B35 alleles and their relationship to HLA-B15 alleles. 
  • Molecular analysis of adenovirus isolates from vaccinated and unvaccinated young adults. 
  • Molecular analysis of the Cryptococcus neoformans ADE2 gene, a selectable marker for transformation and gene disruption. 
  • Molecular and functional characterization of voltage-gated sodium channel variants from Drosophila melanogaster. 
  • Molecular basis of a novel adaptation to hypoxic-hypercapnia in a strictly fossorial mole. 
  • Molecular characterization of CLPT1, a SEC4-like Rab/GTPase of the phytopathogenic fungus Colletotrichum lindemuthianum which is regulated by the carbon source. 
  • Molecular characterization of a highly divergent HIV type 1 isolate obtained early in the AIDS epidemic from the Democratic Republic of Congo. 
  • Molecular characterization of an arachnid sodium channel gene from the varroa mite (Varroa destructor). 
  • Molecular characterization of the spatial diversity and novel lineages of mycoplankton in Hawaiian coastal waters. 
  • Molecular evidence for dual pyrethroid-receptor sites on a mosquito sodium channel. 
  • Molecular evolution of X-linked accessory gland proteins in Drosophila pseudoobscura. 
  • Molecular evolution of a Drosophila homolog of human BRCA2. 
  • Molecular evolutionary dynamics of cytochrome b in strepsirrhine primates: the phylogenetic significance of third-position transversions. 
  • Molecular identification of Aspergillus species collected for the Transplant-Associated Infection Surveillance Network. 
  • Molecular identification, cloning and characterization of transmitted/founder HIV-1 subtype A, D and A/D infectious molecular clones. 
  • Molecular insights into the phylogeny and subgeneric classification of Frullania Raddi (Frullaniaceae, Porellales). 
  • Molecular phylogenetic analysis of the Papionina using concatenation and species tree methods. 
  • Molecular phylogeny of Heteroplacidium, Placidium, and related catapyrenioid genera (Verrucariaceae, lichen-forming Ascomycota). 
  • Molecular phylogeography and cryptic speciation in the mosses, Mielichhoferia elongata and M. mielichhoferiana (Bryaceae). 
  • Molecular recognition of ketamine by a subset of olfactory G protein-coupled receptors. 
  • Molecular typing of clinical adenovirus specimens by an algorithm which permits detection of adenovirus coinfections and intermediate adenovirus strains. 
  • Most environmental isolates of Cryptococcus neoformans var. grubii (serotype A) are not lethal for mice. 
  • Multicenter evaluation of the Vitek 2 anaerobe and Corynebacterium identification card. 
  • Multicenter evaluation of the new Vitek 2 Neisseria-Haemophilus identification card. 
  • Multidonor analysis reveals structural elements, genetic determinants, and maturation pathway for HIV-1 neutralization by VRC01-class antibodies. 
  • Multilocus sequence typing reveals three genetic subpopulations of Cryptococcus neoformans var. grubii (serotype A), including a unique population in Botswana. 
  • Multiple colonisations of the western Indian Ocean by Pteropus fruit bats (Megachiroptera: Pteropodidae): the furthest islands were colonised first. 
  • Multiple origins of high reciprocal symbiotic specificity at an intercontinental spatial scale among gelatinous lichens (Collemataceae, Lecanoromycetes). 
  • Multiple origins of hybrid strains of Cryptococcus neoformans with serotype AD. 
  • Multiple potential regulatory elements in the 5' flanking region of the human alpha 1a-adrenergic receptor. 
  • Multiplex 5' nuclease-quantitative PCR for diagnosis of relapsing fever in a large Tanzanian cohort. 
  • Multiplexed short tandem repeat polymorphisms of the Weber 8A set of markers using tailed primers and infrared fluorescence detection. 
  • Multivariate analysis of associations of 42 genes in ADHD, ODD and conduct disorder. 
  • Murine noroviruses comprising a single genogroup exhibit biological diversity despite limited sequence divergence. 
  • Mutation and overexpression of p53 in early-stage epithelial ovarian cancer. 
  • Mutation exposed: a neutral explanation for extreme base composition of an endosymbiont genome. 
  • Mutation of TBCE causes hypoparathyroidism-retardation-dysmorphism and autosomal recessive Kenny-Caffey syndrome. 
  • Mutation of bcl-x gene in non-Hodgkin's lymphoma. 
  • Mutation screening of patients with Leber Congenital Amaurosis or the enhanced S-Cone Syndrome reveals a lack of sequence variations in the NRL gene. 
  • Mutational Landscapes of Smoking-Related Cancers in Caucasians and African Americans: Precision Oncology Perspectives at Wake Forest Baptist Comprehensive Cancer Center. 
  • Mutational landscapes of tongue carcinoma reveal recurrent mutations in genes of therapeutic and prognostic relevance. 
  • Mutations in CIC and FUBP1 contribute to human oligodendroglioma. 
  • Mutations in NGLY1 cause an inherited disorder of the endoplasmic reticulum-associated degradation pathway. 
  • Mutations in SCO2 are associated with autosomal-dominant high-grade myopia. 
  • Mutations in a gene encoding a novel protein containing a phosphotyrosine-binding domain cause type 2 cerebral cavernous malformations. 
  • Mutations in isocitrate dehydrogenase 1 and 2 occur frequently in intrahepatic cholangiocarcinomas and share hypermethylation targets with glioblastomas. 
  • Mutations in the glucose-6-phosphatase gene are associated with glycogen storage disease types 1a and 1aSP but not 1b and 1c. 
  • Mutations of the Ki-ras oncogene in endometrial carcinoma. 
  • Myotilin is mutated in limb girdle muscular dystrophy 1A. 
  • NPAS3 is a trachealess homolog critical for lung development and homeostasis. 
  • Nanopore sequencing of complex genomic rearrangements in yeast reveals mechanisms of repeat-mediated double-strand break repair. 
  • Natural IgM is produced by CD5- plasma cells that occupy a distinct survival niche in bone marrow. 
  • Nature and distribution of large sequence polymorphisms in Saccharomyces cerevisiae. 
  • Neutralization activity in a geographically diverse East London cohort of human immunodeficiency virus type 1-infected patients: clade C infection results in a stronger and broader humoral immune response than clade B infection. 
  • New Member of the V1V2-Directed CAP256-VRC26 Lineage That Shows Increased Breadth and Exceptional Potency. 
  • New routes to targeted therapy of intrahepatic cholangiocarcinomas revealed by next-generation sequencing. 
  • New simian immunodeficiency virus infecting De Brazza's monkeys (Cercopithecus neglectus): evidence for a cercopithecus monkey virus clade. 
  • New species and distribution records for Clavulina (Cantharellales, Basidiomycota) from the Guiana Shield, with a key to the lowland neotropical taxa. 
  • New species of Xerocomus (Boletales) from the Guiana Shield, with notes on their mycorrhizal status and fruiting occurrence. 
  • New techniques for DNA sequence classification. 
  • Newborns of obese parents have altered DNA methylation patterns at imprinted genes. 
  • Next-generation genotyping of hypervariable loci in many individuals of a non-model species: technical and theoretical implications. 
  • Next-generation polyploid phylogenetics: rapid resolution of hybrid polyploid complexes using PacBio single-molecule sequencing. 
  • Next-generation sequencing of the human olfactory receptors. 
  • No evidence for maternal-fetal microchimerism in infantile hemangioma: a molecular genetic investigation. 
  • No evidence for the presence of genetic variants predisposing to psychotic disorders on the non-deleted 22q11.2 allele of VCFS patients. 
  • Nonmuscle myosin II generates forces that transmit tension and drive contraction in multiple tissues during dorsal closure. 
  • Novel Insights into Chromosome Evolution in Birds, Archosaurs, and Reptiles. 
  • Novel associations of UDP-glucuronosyltransferase 2B gene variants with prostate cancer risk in a multiethnic study. 
  • Novel circular DNA viruses in stool samples of wild-living chimpanzees. 
  • Novel enriched pathways in superficial malignant peripheral nerve sheath tumours and spindle/desmoplastic melanomas. 
  • Novel forms of structural integration between microbes and a hydrothermal vent gastropod from the Indian Ocean. 
  • Novel intronic DICER1 variation associated with pleuropulmonary blastoma in two siblings. 
  • Nubeam-dedup: a fast and RAM-efficient tool to de-duplicate sequencing reads without mapping. 
  • Nucleic Acid Databases and Molecular-Scale Computing. 
  • O6-Methylguanine DNA Methyltransferase Status Does Not Predict Response or Resistance to Alkylating Agents in Well-Differentiated Pancreatic Neuroendocrine Tumors. 
  • Observation of dually decoded regions of the human genome using ribosome profiling data. 
  • Obtaining mtDNA genomes from next-generation transcriptome sequencing: a case study on the basal Passerida (Aves: Passeriformes) phylogeny. 
  • Of urchins and men: evolution of an alternative splicing unit in fibroblast growth factor receptor genes. 
  • Olfactory Receptor Subgenomes Linked with Broad Ecological Adaptations in Sauropsida. 
  • Oncogenic CARD11 mutations in human diffuse large B cell lymphoma. 
  • One haploid parent contributes 100% of the gene pool for a widespread species in northwest North America. 
  • One nutritional symbiosis begat another: phylogenetic evidence that the ant tribe Camponotini acquired Blochmannia by tending sap-feeding insects. 
  • One species or at least eight? Delimitation and distribution of Frullania tamarisci (L.) Dumort. s. l. (Jungermanniopsida, Porellales) inferred from nuclear and chloroplast DNA markers. 
  • Ontogenetic Differences in Dietary Fat Influence Microbiota Assembly in the Zebrafish Gut. 
  • Open chromatin defined by DNaseI and FAIRE identifies regulatory elements that shape cell-type identity. 
  • Organellar phylogenomics of an emerging model system: Sphagnum (peatmoss). 
  • Organization and evolutionary trajectory of the mating type (MAT) locus in dermatophyte and dimorphic fungal pathogens. 
  • Organization of carboxysome genes in the thiobacilli. 
  • Organization of the MASP2 locus and its expression profile in mouse and rat. 
  • Origin and evolution of HIV-1 in breast milk determined by single-genome amplification and sequencing. 
  • Origin of HIV-1 in the chimpanzee Pan troglodytes troglodytes. 
  • Outbreak of febrile respiratory illness associated with human adenovirus type 14p1 in Gansu Province, China. 
  • Ovarian cycling and reproductive state shape the vaginal microbiota in wild baboons. 
  • Overcoming redundancy: an RNAi enhancer screen for morphogenesis genes in Caenorhabditis elegans. 
  • POWRS: position-sensitive motif discovery. 
  • PSORS2 is due to mutations in CARD14. 
  • Paediatric leukaemia DNA methylation profiling using MBD enrichment and SOLiD sequencing on archival bone marrow smears. 
  • Paired-end analysis of transcription start sites in Arabidopsis reveals plant-specific promoter signatures. 
  • Parallel acceleration of evolutionary rates in symbiont genes underlying host nutrition. 
  • Parallel on-chip gene synthesis and application to optimization of protein expression. 
  • Partial resistance to infection by R5X4 primary HIV type 1 isolates in an exposed-uninfected individual homozygous for CCR5 32-base pair deletion. 
  • Patterns of gut bacterial colonization in three primate species. 
  • Patterns of nucleotide diversity in two species of Mimulus are affected by mating system and asymmetric introgression. 
  • Peatmoss (Sphagnum) diversification associated with Miocene Northern Hemisphere climatic cooling? 
  • Pembrolizumab in men with heavily treated metastatic castrate-resistant prostate cancer. 
  • Performance assessment of promoter predictions on ENCODE regions in the EGASP experiment. 
  • Pervasive migration across rainforest and sandy coastal plain Aechmea nudicaulis (Bromeliaceae) populations despite contrasting environmental conditions. 
  • Phenotypic properties of transmitted founder HIV-1. 
  • Phospholipid-binding protein Cts1 controls septation and functions coordinately with calcineurin in Cryptococcus neoformans. 
  • Photoautotrophic symbiont and geography are major factors affecting highly structured and diverse bacterial communities in the lichen microbiome. 
  • Phylogenetic affiliations of members of the heterogeneous lichen-forming fungi of the genus Lecidea sensu Zahlbruckner (Lecanoromycetes, Ascomycota). 
  • Phylogenetic analyses of eurotiomycetous endophytes reveal their close affinities to Chaetothyriales, Eurotiales, and a new order - Phaeomoniellales. 
  • Phylogenetic analyses of morphological evolution in the gametophyte and sporophyte generations of the moss order Hookeriales (Bryopsida). 
  • Phylogenetic analysis of protease and transmembrane region of HIV type 1 group O. 
  • Phylogenetic analysis of viridans group streptococci causing endocarditis. 
  • Phylogenetic and biogeographic relationships of eastern Asian and eastern North American disjunct Suillus species (fungi) as inferred from nuclear ribosomal RNA ITS sequences. 
  • Phylogenetic comparison of protein-coding versus ribosomal RNA-coding sequence data: a case study of the Lecanoromycetes (Ascomycota). 
  • Phylogenetic evidence of a rapid radiation of pleurocarpous mosses (Bryophyta). 
  • Phylogenetic reassessment of the Teloschistaceae (lichen-forming Ascomycota, Lecanoromycetes). 
  • Phylogenetic relationships of Rhizoctonia fungi within the Cantharellales. 
  • Phylogenetic relationships, host affinity, and geographic structure of boreal and arctic endophytes from three major plant lineages. 
  • Phylogenetic relationships, morphological incongruence, and geographic speciation in the fontinalaceae (Bryophyta). 
  • Phylogenomic inferences from reference-mapped and de novo assembled short-read sequence data using RADseq sequencing of California white oaks (Quercus section Quercus). 
  • Phylogenomics reveals a complex evolutionary history of lobed-leaf white oaks in western North America. 
  • Phylogeny and biogeography of East Asian evergreen oaks (Quercus section Cyclobalanopsis; Fagaceae): Insights into the Cenozoic history of evergreen broad-leaved forests in subtropical Asia. 
  • Phylogeny and biogeography of the American live oaks (Quercus subsection Virentes): a genomic and population genetics approach. 
  • Phylogeny and evolution of Malagasy plated lizards. 
  • Phylogeny and taxonomy of the family Arthrodermataceae (dermatophytes) using sequence analysis of the ribosomal ITS region. 
  • Phylogeny of the Gyalectales and Ostropales (Ascomycota, Fungi): among and within order relationships based on nuclear ribosomal RNA small and large subunits. 
  • Phylogeny of the leafy liverwort Ptilidium: cryptic speciation and shared haplotypes between the Northern and Southern Hemispheres. 
  • Phylogeny, biogeography, and processes of molecular differentiation in Quercus subgenus Quercus (Fagaceae). 
  • Phylogeography of the Solanaceae-infecting Basidiomycota fungus Rhizoctonia solani AG-3 based on sequence analysis of two nuclear DNA loci. 
  • Physical maps for genome analysis of serotype A and D strains of the fungal pathogen Cryptococcus neoformans. 
  • Picoliter DNA sequencing chemistry on an electrowetting-based digital microfluidic platform. 
  • Plant host and soil origin influence fungal and bacterial assemblages in the roots of woody plants. 
  • Points to consider in the reevaluation and reanalysis of genomic test results: a statement of the American College of Medical Genetics and Genomics (ACMG). 
  • Polymorphic markers of the glycogen debranching enzyme gene allowing linkage analysis in families with glycogen storage disease type III. 
  • Polymorphisms in Fibronectin Binding Proteins A and B among Staphylococcus aureus Bloodstream Isolates Are Not Associated with Arthroplasty Infection. 
  • Pooled deep sequencing of Plasmodium falciparum isolates: an efficient and scalable tool to quantify prevailing malaria drug-resistance genotypes. 
  • Population history in Arabidopsis halleri using multilocus analysis. 
  • Positional clustering improves computational binding site detection and identifies novel cis-regulatory sites in mammalian GABAA receptor subunit genes. 
  • Positive selection driving diversification in plant secondary metabolism. 
  • Positive selection on MMP3 regulation has shaped heart disease risk. 
  • Potential of whole-genome sequencing for determining risk and personalizing therapy: focus on AML. 
  • Practical Treatment Strategies and Future Directions After Progression While Receiving CDK4/6 Inhibition and Endocrine Therapy in Advanced HR+/HER2- Breast Cancer. 
  • Practical considerations in the clinical application of whole-exome sequencing. 
  • Precise localization of the FHIT gene to the common fragile site at 3p14.2 (FRA3B) and characterization of homozygous deletions within FRA3B that affect FHIT transcription in tumor cell lines. 
  • Precise mapping of recombination breakpoints suggests a common parent of two BC recombinant HIV type 1 strains circulating in China. 
  • Precise spatio-temporal regulation of the anthocyanin biosynthetic pathway leads to petal spot formation in Clarkia gracilis (Onagraceae). 
  • Prediction of HIV Transmission Cluster Growth With Statewide Surveillance Data. 
  • Prediction of genome-wide DNA methylation in repetitive elements. 
  • Pregnancy without progesterone in horses defines a second endogenous biopotent progesterone receptor agonist, 5α-dihydroprogesterone. 
  • Preparation, resonance assignment, and preliminary dynamics characterization of residue specific 13C/15N-labeled elongated DNA for the study of sequence-directed dynamics by NMR. 
  • Presence of diverse human immunodeficiency virus type 1 viral variants in Cameroon. 
  • Prevalence of deleterious ATM germline mutations in gastric cancer patients. 
  • Prevalence of hepatitis B antiviral drug resistance variants in North American patients with chronic hepatitis B not receiving antiviral treatment. 
  • Prochlorococcus ecotype abundances in the North Atlantic Ocean as revealed by an improved quantitative PCR method. 
  • Progressive island colonization and ancient origin of Hawaiian Metrosideros (Myrtaceae). 
  • Promoter prediction on a genomic scale--the Adh experience. 
  • Protection afforded by an HIV vaccine candidate in macaques depends on the dose of SIVmac251 at challenge exposure. 
  • Purification, cDNA sequence, and tissue distribution of rat uroguanylin. 
  • Quantitating the multiplicity of infection with human immunodeficiency virus type 1 subtype C reveals a non-poisson distribution of transmitted variants. 
  • RGSZ1, a Gz-selective regulator of G protein signaling whose action is sensitive to the phosphorylation state of Gzalpha. 
  • ROR alpha augments thyroid hormone receptor-mediated transcriptional activation. 
  • Rank order metrics for quantifying the association of sequence features with gene regulation. 
  • Rapid DNA sequencing of more than 1000 bases per run by capillary electrophoresis using replaceable linear polyacrylamide solutions. 
  • Rapid mapping of insertional mutations to probe cell wall regulation in Cryptococcus neoformans. 
  • Rare codons regulate KRas oncogenesis. 
  • Reading, writing, and modulating genetic information with boranophosphate mimics of nucleotides, DNA, and RNA. 
  • Realizing the opportunities of genomics in health care. 
  • Recombination between palindromes P5 and P1 on the human Y chromosome causes massive deletions and spermatogenic failure. 
  • Reconstructing the temporal ordering of biological samples using microarray data. 
  • Refinement of the PARK3 locus on chromosome 2p13 and the analysis of 14 candidate genes. 
  • Refugial isolation and range expansions drive the genetic structure of Oxyria sinensis (Polygonaceae) in the Himalaya-Hengduan Mountains. 
  • Regional clustering of shared neutralization determinants on primary isolates of clade C human immunodeficiency virus type 1 from South Africa. 
  • Regulation of basement membrane-reactive B cells in BXSB, (NZBxNZW)F1, NZB, and MRL/lpr lupus mice. 
  • Regulation of cytochrome c oxidase subunit 1 (COX1) expression in Cryptococcus neoformans by temperature and host environment. 
  • Relaxed constraint and evolutionary rate variation between basic helix-loop-helix floral anthocyanin regulators in Ipomoea. 
  • Remarkably little variation in proteins encoded by the Y chromosome's single-copy genes, implying effective purifying selection. 
  • Removal of polymerase-produced mutant sequences from PCR products. 
  • Repeated phenotypic changes highlight molecular targets of convergent evolution. 
  • Replication of the recessive STBMS1 locus but with dominant inheritance. 
  • Report and abstracts of the sixth international workshop on human chromosome 1 mapping 2000. Iowa City, Iowa, USA. 30 September-3 October 2000. 
  • Report and abstracts of the third international workshop on human chromosome 1 mapping 1997. 
  • Report of the fifth international workshop on human chromosome 1 mapping 1999. 
  • Resequencing Study Confirms That Host Defense and Cell Senescence Gene Variants Contribute to the Risk of Idiopathic Pulmonary Fibrosis. 
  • Resistance mechanisms for the Bruton's tyrosine kinase inhibitor ibrutinib. 
  • Resistance mutations at the lipid substrate binding site of Plasmodium falciparum protein farnesyltransferase. 
  • Responses of soil cellulolytic fungal communities to elevated atmospheric CO₂ are complex and variable across five ecosystems. 
  • Reversion and T cell escape mutations compensate the fitness loss of a CD8+ T cell escape mutant in their cognate transmitted/founder virus. 
  • Revolution and renaissance. 
  • RoBo-1, a novel member of the urokinase plasminogen activator receptor/CD59/Ly-6/snake toxin family selectively expressed in rat bone and growth plate cartilage. 
  • Role of Cdc42p in pheromone-stimulated signal transduction in Saccharomyces cerevisiae. 
  • Role of Escherichia coli DNA polymerase I in conferring viability upon the dnaN159 mutant strain. 
  • Role of the angiotensin type 2 receptor gene in congenital anomalies of the kidney and urinary tract, CAKUT, of mice and men. 
  • SCAR, a WASP-related protein, isolated as a suppressor of receptor defects in late Dictyostelium development. 
  • SIV-induced instability of the chimpanzee gut microbiome. 
  • SNP-skimming: A fast approach to map loci generating quantitative variation in natural populations. 
  • SNPselector: a web tool for selecting SNPs for genetic association studies. 
  • SVA: software for annotating and visualizing sequenced human genomes. 
  • Sakacin P non-producing Lactobacillus sakei strains contain homologues of the sakacin P gene cluster. 
  • Scalable Open Science Approach for Mutation Calling of Tumor Exomes Using Multiple Genomic Pipelines. 
  • Screening of 181 Patients With Antibody Deficiency for Deficiency of Adenosine Deaminase 2 Sheds New Light on the Disease in Adulthood. 
  • Screening the human exome: a comparison of whole genome and whole transcriptome sequencing. 
  • Scythe: a novel reaper-binding apoptotic regulator. 
  • Selective sweeps and intercontinental migration in the cosmopolitan moss Ceratodon purpureus (Hedw.) Brid. 
  • Self-reported prenatal tobacco smoke exposure, AXL gene-body methylation, and childhood asthma phenotypes. 
  • Sensitivity of the ViroSeq HIV-1 genotyping system for detection of the K103N resistance mutation in HIV-1 subtypes A, C, and D. 
  • SeqSIMLA2: simulating correlated quantitative traits accounting for shared environmental effects in user-specified pedigree structure. 
  • Sequence analysis of a cDNA for lysyl hydroxylase isolated from human skin fibroblasts from a normal donor: differences from human placental lysyl hydroxylase cDNA. 
  • Sequence features of DNA binding sites reveal structural class of associated transcription factor. 
  • Sequence specificity incompletely defines the genome-wide occupancy of Myc. 
  • Sequence variants in the transforming growth beta-induced factor (TGIF) gene are not associated with high myopia. 
  • Sequence-Based Screening of Patients With Idiopathic Polyarteritis Nodosa, Granulomatosis With Polyangiitis, and Microscopic Polyangiitis for Deleterious Genetic Variants in ADA2. 
  • Sequence-based differentiation of strains in the Mycobacterium avium complex. 
  • Sequencing analysis of the ATOH7 gene in individuals with optic nerve hypoplasia. 
  • Sequencing and analysis of genomic fragments from the NF1 locus. 
  • Sequencing of double-stranded polymerase chain reaction products for mutation analysis. 
  • Sequencing studies in human genetics: design and interpretation. 
  • Sequencing the mouse Y chromosome reveals convergent gene acquisition and amplification on both sex chromosomes. 
  • Sequencing three crocodilian genomes to illuminate the evolution of archosaurs and amniotes. 
  • She Loves Me, She Loves Me Not: On the Dualistic Asexual/Sexual Nature of Dermatophyte Fungi. 
  • Short communication: HIV type 1 subtype C variants transmitted through the bottleneck of breastfeeding are sensitive to new generation broadly neutralizing antibodies directed against quaternary and CD4-binding site epitopes. 
  • Signaling activities of the Drosophila wingless gene are separately mutable and appear to be transduced at the cell surface. 
  • Simultaneous detection of major drug resistance mutations in the protease and reverse transcriptase genes for HIV-1 subtype C by use of a multiplex allele-specific assay. 
  • Simultaneous genotyping and species identification using hybridization pattern recognition analysis of generic Mycobacterium DNA arrays. 
  • Site-specific retinoic acid production in the brain of adult songbirds. 
  • Slow algae, fast fungi: exceptionally high nucleotide substitution rate differences between lichenized fungi Omphalina and their symbiotic green algae Coccomyxa. 
  • Social networks predict gut microbiome composition in wild baboons. 
  • Somatic Mutation Allelic Ratio Test Using ddPCR (SMART-ddPCR): An Accurate Method for Assessment of Preferential Allelic Imbalance in Tumor DNA. 
  • SpA: web-accessible spectratype analysis: data management, statistical analysis and visualization. 
  • Species delimitation and biogeography of a southern hemisphere liverwort clade, Frullania subgenus Microfrullania (Frullaniaceae, Marchantiophyta). 
  • Species delimitation in lemurs: multiple genetic loci reveal low levels of species diversity in the genus Cheirogaleus. 
  • Species discovery and validation in a cryptic radiation of endangered primates: coalescent-based species delimitation in Madagascar's mouse lemurs. 
  • Specific polymorphisms in hepatitis C virus genotype 3 core protein associated with intracellular lipid accumulation. 
  • Sperm DNA methylation altered by THC and nicotine: Vulnerability of neurodevelopmental genes with bivalent chromatin. 
  • Spliceosome-mediated RNA trans-splicing as a tool for gene therapy. 
  • Stabilization of microsatellite sequences by variant repeats in the yeast Saccharomyces cerevisiae. 
  • Statistical analysis of genetic interactions in Tn-Seq data. 
  • Strain-Specific V3 and CD4 Binding Site Autologous HIV-1 Neutralizing Antibodies Select Neutralization-Resistant Viruses. 
  • Stratified whole genome linkage analysis of Chiari type I malformation implicates known Klippel-Feil syndrome genes as putative disease candidates. 
  • Structure of the genes encoding transcription factor IIB and TATA box-binding protein from Drosophila melanogaster. 
  • Structure, function, and phylogeny of the mating locus in the Rhizopus oryzae complex. 
  • Structure-guided reprogramming of serine recombinase DNA sequence specificity. 
  • Study of a US cohort supports the role of ZNF644 and high-grade myopia susceptibility. 
  • Sturge-Weber syndrome and port-wine stains caused by somatic mutation in GNAQ. 
  • Successful diagnosis of HIBCH deficiency from exome sequencing and positive retrospective analysis of newborn screening cards in two siblings presenting with Leigh's disease. 
  • Superoxide dismutase influences the virulence of Cryptococcus neoformans by affecting growth within macrophages. 
  • Surface-enhanced Raman gene probes. 
  • Survey of corticioid fungi in North American pinaceous forests reveals hyperdiversity, underpopulated sequence databases, and species that are potentially ectomycorrhizal. 
  • Survey of variation in human transcription factors reveals prevalent DNA binding changes. 
  • Sustained elite suppression of replication competent HIV-1 in a patient treated with rituximab based chemotherapy. 
  • Sympatric parallel diversification of major oak clades in the Americas and the origins of Mexican species diversity. 
  • Synchronous luminescence: a new detection technique for multiple fluorescent probes used for DNA sequencing. 
  • Syndrome of hepatic cirrhosis, dystonia, polycythemia, and hypermanganesemia caused by mutations in SLC30A10, a manganese transporter in man. 
  • Synonymous codon usage analysis of hand, foot and mouth disease viruses: A comparative study on coxsackievirus A6, A10, A16, and enterovirus 71 from 2008 to 2015. 
  • Systematics of the genus Chaetosphaeria and its allied genera: morphological and phylogenetic diversity in north temperate and neotropical taxa. 
  • TNXB mutations can cause vesicoureteral reflux. 
  • Targeted Re-Sequencing Emulsion PCR Panel for Myopathies: Results in 94 Cases. 
  • Targeted sequencing in chromosome 17q linkage region identifies familial glioma candidates in the Gliogene Consortium. 
  • Telaprevir for previously untreated chronic hepatitis C virus infection. 
  • Temporal Stability of Molecular Diversity Measures in Natural Populations of Drosophila pseudoobscura and Drosophila persimilis. 
  • Testing Rare-Variant Association without Calling Genotypes Allows for Systematic Differences in Sequencing between Cases and Controls. 
  • Testing for divergent transmission histories among cultural characters: a study using Bayesian phylogenetic methods and Iranian tribal textile data. 
  • Testing morphological concepts of orders of pleurocarpous mosses (Bryophyta) using phylogenetic reconstructions based on TRNL-TRNF and RPS4 sequences. 
  • Testing the effect of rare compound-heterozygous and recessive mutations in case--parent sequencing studies. 
  • The A581G Mutation in the Gene Encoding Plasmodium falciparum Dihydropteroate Synthetase Reduces the Effectiveness of Sulfadoxine-Pyrimethamine Preventive Therapy in Malawian Pregnant Women. 
  • The AZFc region of the Y chromosome features massive palindromes and uniform recurrent deletions in infertile men. 
  • The Arabidopsis NPR1 gene that controls systemic acquired resistance encodes a novel protein containing ankyrin repeats. 
  • The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces cerevisiae genome. 
  • The Cryptococcus neoformans genome sequencing project. 
  • The DNA methylation landscape of advanced prostate cancer. 
  • The DNA sequence and biological annotation of human chromosome 1. 
  • The DNA sequence of the human X chromosome. 
  • The Danish 1905 cohort: a genetic-epidemiological nationwide survey. 
  • The Drosophila Tis11 protein and its effects on mRNA expression in flies. 
  • The ENCODE (ENCyclopedia Of DNA Elements) Project. 
  • The GroES antigens of Mycobacterium avium and Mycobacterium paratuberculosis. 
  • The ICP0 protein of equine herpesvirus 1 is an early protein that independently transactivates expression of all classes of viral promoters. 
  • The Influenza B Virus Hemagglutinin Head Domain Is Less Tolerant to Transposon Mutagenesis than That of the Influenza A Virus. 
  • The LabFlow system for workflow management in large scale biology research laboratories. 
  • The MedSeq Project: a randomized trial of integrating whole genome sequencing into clinical medicine. 
  • The Pleistocene history of the sheepshead minnow (Cyprinodon variegatus): Non-equilibrium evolutionary dynamics within a diversifying species complex. 
  • The Populus holobiont: dissecting the effects of plant niches and genotype on the microbiome. 
  • The Pseudomonas syringae pv. tomato HrpW protein has domains similar to harpins and pectate lyases and can elicit the plant hypersensitive response and bind to pectate. 
  • The RAM1 gene encoding a protein-farnesyltransferase beta-subunit homologue is essential in Cryptococcus neoformans. 
  • The Sphagnome Project: enabling ecological and evolutionary insights through a genus-level sequencing project. 
  • The adaptive radiation of lichen-forming Teloschistaceae is associated with sunscreening pigments and a bark-to-rock substrate shift. 
  • The calmodulin-dependent protein phosphatase catalytic subunit (calcineurin A) is an essential gene in Aspergillus nidulans. 
  • The calmodulin-dependent protein phosphatase catalytic subunit (calcineurin A) is an essential gene in Aspergillus nidulans. 
  • The cantharelloid clade: dealing with incongruent gene trees and phylogenetic reconstruction methods. 
  • The characterization of twenty sequenced human genomes. 
  • The cyanide-resistant alternative oxidases from the fungi Pichia stipitis and Neurospora crassa are monomeric and lack regulatory features of the plant enzyme. 
  • The dangers of diagnostic monopolies. 
  • The differential expression of wound-inducible lipoxygenase genes in soybean leaves. 
  • The draft genome of the transgenic tropical fruit tree papaya (Carica papaya Linnaeus). 
  • The earliest stages of adaptation in an experimental plant population: strong selection on QTLS for seed dormancy. 
  • The ectomycorrhizal fungal community in a neotropical forest dominated by the endemic dipterocarp Pakaraimaea dipterocarpacea. 
  • The effect of sequence context on spontaneous Polzeta-dependent mutagenesis in Saccharomyces cerevisiae. 
  • The effects of Cenozoic global change on squirrel phylogeny. 
  • The evolution of homing endonuclease genes and group I introns in nuclear rDNA. 
  • The evolutionary forest algorithm. 
  • The evolutionary history of ferns inferred from 25 low-copy nuclear genes. 
  • The extent and genetic basis of phenotypic divergence in life history traits in Mimulus guttatus. 
  • The founding of Mauritian endemic coffee trees by a synchronous long-distance dispersal event. 
  • The genetic landscape of mutations in Burkitt lymphoma. 
  • The genetic landscape of the childhood cancer medulloblastoma. 
  • The genome of the basidiomycetous yeast and human pathogen Cryptococcus neoformans. 
  • The genome of the sea urchin Strongylocentrotus purpuratus. 
  • The genomic consequences of adaptive divergence and reproductive isolation between species of manakins. 
  • The genomic landscape of mantle cell lymphoma is related to the epigenetically determined chromatin state of normal B cells. 
  • The genomics of speciation in Drosophila: diversity, divergence, and introgression estimated using low-coverage genome sequencing. 
  • The human gene for the type III isozyme of hexokinase: structure, basal promoter, and evolution. 
  • The lemur revolution starts now: the genomic coming of age for a non-model organism. 
  • The mammalian Rad24 homologous to yeast Saccharomyces cerevisiae Rad24 and Schizosaccharomyces pombe Rad17 is involved in DNA damage checkpoint. 
  • The near-naked hairless (Hr(N)) mutation disrupts hair formation but is not due to a mutation in the Hairless coding region. 
  • The prevalence and regulation of antisense transcripts in Schizosaccharomyces pombe. 
  • The reference genome sequence of Saccharomyces cerevisiae: then and now. 
  • The same sequence variant on 9p21 associates with myocardial infarction, abdominal aortic aneurysm and intracranial aneurysm. 
  • The smallest membrane anchoring subunit (QPs3) of bovine heart mitochondrial succinate-ubiquinone reductase. Cloning, sequencing, topology, and Q-binding domain. 
  • The spatial factor, rather than elevated CO₂, controls the soil bacterial community in a temperate Forest Ecosystem. 
  • The spatial scale of genetic subdivision in populations of Ifremeria nautilei, a hydrothermal-vent gastropod from the southwest Pacific. 
  • The trehalose synthesis pathway is an integral part of the virulence composite for Cryptococcus gattii. 
  • The urinary microbiome in women with mixed urinary incontinence compared to similarly aged controls. 
  • The utility of PacBio circular consensus sequencing for characterizing complex gene families in non-model organisms. 
  • The utility of the incongruence length difference test. 
  • The utility of the traditional medical genetics diagnostic evaluation in the context of next-generation sequencing for undiagnosed genetic disorders. 
  • The white gene of the tephritid fruit fly Bactrocera tryoni is characterized by a long untranslated 5' leader and a 12kb first intron. 
  • The yeast carboxyl-terminal repeat domain kinase CTDK-I is a divergent cyclin-cyclin-dependent kinase complex. 
  • Theoretical and practical advances in genome halving. 
  • Three crocodilian genomes reveal ancestral patterns of evolution among archosaurs. 
  • Three-genome mosses: complex double allopolyploid origins for triploid gametophytes in Sphagnum. 
  • Tigecycline therapy for carbapenem-resistant Klebsiella pneumoniae (CRKP) bacteriuria leads to tigecycline resistance. 
  • Timing of complementary feeding is associated with gut microbiota diversity and composition and short chain fatty acid concentrations over the first year of life. 
  • Tissue distribution and thyroid hormone effects on mRNA abundance for membrane transporters Mct8, Mct10, and organic anion-transporting polypeptides (Oatps) in a teleost fish. 
  • Tissue storage and primer selection influence pyrosequencing-based inferences of diversity and community composition of endolichenic and endophytic fungi. 
  • Toward a Wolbachia multilocus sequence typing system: discrimination of Wolbachia strains present in Drosophila species. 
  • Toward deciphering the mechanistic role of variations in the Rep1 repeat site in the transcription regulation of SNCA gene. 
  • Towards Quantitative Microbiome Community Profiling Using Internal Standards. 
  • Towards a new classification of the Arthoniales (Ascomycota) based on a three-gene phylogeny focussing on the genus Opegrapha. 
  • Transcriptome analysis of mouse stem cells and early embryos. 
  • Transcriptome-mining for single-copy nuclear markers in ferns. 
  • Transient compartmentalization of simian immunodeficiency virus variants in the breast milk of african green monkeys. 
  • Transmission of single HIV-1 genomes and dynamics of early immune escape revealed by ultra-deep sequencing. 
  • Treponema pallidum infection in the wild baboons of East Africa: distribution and genetic characterization of the strains responsible. 
  • Trilateral retinoblastoma in a patient with Peutz-Jeghers syndrome. 
  • Trio-based exome sequencing arrests de novo mutations in early-onset high myopia. 
  • Type II collagen gene variants and inherited osteonecrosis of the femoral head. 
  • Ultra-rare genetic variation in common epilepsies: a case-control sequencing study. 
  • Unique expression of a sporophytic character on the gametophytes of notholaenid ferns (Pteridaceae). 
  • Use of bioinformatic tools in primer validation. 
  • Using ERDS to infer copy-number variants in high-coverage genomes. 
  • Using a multigene phylogenetic analysis to assess generic delineation and character evolution in Verrucariaceae (Verrucariales, Ascomycota). 
  • Using comparative genomic data to test for fast-X evolution. 
  • Vaccination with the immediate-early protein ICP47 of herpes simplex virus-type 1 (HSV-1) induces virus-specific lymphoproliferation, but fails to protect against lethal challenge. 
  • Variable but persistent coexistence of Prochlorococcus ecotypes along temperature gradients in the ocean's surface mixed layer. 
  • Variant ASGR1 Associated with a Reduced Risk of Coronary Artery Disease. 
  • Variants in CXCR4 associate with juvenile idiopathic arthritis susceptibility. 
  • Variants in melanocortin 1 receptor gene contribute to risk of melanoma--a direct sequencing analysis in a Texas population. 
  • Variation in GRM3 affects cognition, prefrontal glutamate, and risk for schizophrenia. 
  • VarioWatch: providing large-scale and comprehensive annotations on human genomic variants in the next generation sequencing era. 
  • Vibrio metoecus sp. nov., a close relative of Vibrio cholerae isolated from coastal brackish ponds and clinical specimens. 
  • Vironome of Kaposi sarcoma associated herpesvirus-inflammatory cytokine syndrome in an AIDS patient reveals co-infection of human herpesvirus 8 and human herpesvirus 6A. 
  • Virulence determinants in the obligate intracellular pathogen Chlamydia trachomatis revealed by forward genetic approaches. 
  • WASABI: an automated sequence processing system for multigene phylogenies. 
  • West Nile virus in Mexico: evidence of widespread circulation since July 2002. 
  • What can you do with 0.1x genome coverage? A case study based on a genome survey of the scuttle fly Megaselia scalaris (Phoridae). 
  • Whole genome re-sequencing to identify suppressor mutations of mutant and foreign Escherichia coli FtsZ. 
  • Whole genome sequencing identifies circulating Beijing-lineage Mycobacterium tuberculosis strains in Guatemala and an associated urban outbreak. 
  • Whole-exome sequencing implicates UBE3D in age-related macular degeneration in East Asian populations. 
  • Whole-genome analyses resolve early branches in the tree of life of modern birds. 
  • Whole-genome comparison of Leu3 binding in vitro and in vivo reveals the importance of nucleosome occupancy in target site selection. 
  • Whole-genome fingerprint of the DNA methylome during human B cell differentiation. 
  • Wide variation in the multiplicity of HIV-1 infection among injection drug users. 
  • Working at the interface of phylogenetics and population genetics: a biogeographical analysis of Triaenops spp. (Chiroptera: Hipposideridae). 
  • Yantar, a conserved arginine-rich protein is involved in Drosophila hemocyte development. 
  • Yeast diversity sampling on the San Juan Islands reveals no evidence for the spread of the Vancouver Island Cryptococcus gattii outbreak to this locale. 
  • Young Investigator Challenge: Molecular testing in noninvasive follicular thyroid neoplasm with papillary-like nuclear features. 
  • [PCR amplification and structural analysis of two paralogous rat estrogen sulfotransferase genes]. 
  • alphaSU2, an epithelial integrin that binds laminin in the sea urchin embryo. 
  • cnvCapSeq: detecting copy number variation in long-range targeted resequencing data. 
  • hrp gene-dependent induction of hin1: a plant gene activated rapidly by both harpins and the avrPto gene-mediated signal. 
  • mirror encodes a novel PBX-class homeoprotein that functions in the definition of the dorsal-ventral border in the Drosophila eye. 
• 

  Keywords of People

  • Alberts, Susan C., Robert F. Durden Distinguished Professor of Biology, Duke Science & Society
  • Bejsovec, Amy, Associate Professor of Biology, Biology
  • Berchuck, Andrew, James M. Ingram Distinguished Professor of Gynecologic Oncology, Obstetrics and Gynecology, Gynecologic Oncology
  • Buckley, Rebecca Hatcher, James Buren Sidbury Distinguished Professor of Pediatrics, in the School of Medicine, Immunology
  • Cunningham, Coleen Kathryn, Adjunct Professor in the Department of Pediatrics, Pediatrics
  • Erickson, Harold Paul, James B. Duke Distinguished Professor of Cell Biology, Cell Biology
  • Gordan, Raluca Mihaela, Associate Professor in Biostatistics & Bioinformatics, Computer Science
  • Gunn, Michael Dee, Professor of Medicine, Immunology
  • Hartemink, Alexander J., Professor in the Department of Computer Science, Biology
  • Hogan, Brigid L. M., George Barth Geller Distinguished Professor for Research in Molecular Biology, Cell Biology
  • Li, Yi-Ju, Professor of Biostatistics and Bioinformatics, Biostatistics & Bioinformatics
  • Liu, Yutao, Adjunct Assistant Professor in the Department of Medicine, Medicine, Medical Genetics
  • McLendon, Roger Edwin, Professor of Pathology, Pathology
  • Mitchell-Olds, Thomas, Newman Ivey White Distinguished Professor of Biology, Biology
  • Noor, Mohamed A. F., Professor of Biology, Duke Science & Society
  • Roth, V. Louise, Professor of Biology, Evolutionary Anthropology
  • Shinohara, Mari L., Associate Professor of Immunology, Immunology
  • Wray, Gregory Allan, Professor of Biology, Duke Innovation & Entrepreneurship
  • Yan, Hai, Henry S. Friedman Distinguished Professor of Neuro-Oncology in the School of Medicine, Pathology
  • Yoder, Anne Daphne, Braxton Craven Distinguished Professor of Evolutionary Biology, Duke University