Sequence Analysis, DNA

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  Subject Areas on Research

  • "Smart" DNA interfaces. 
  • 4.5 kb of the rat tyrosine hydroxylase 5' flanking sequence directs tissue specific expression during development and contains consensus sites for multiple transcription factors. 
  • A Flexible, Efficient Binomial Mixed Model for Identifying Differential DNA Methylation in Bisulfite Sequencing Data. 
  • A Fringe-modified Notch signal affects specification of mesoderm and endoderm in the sea urchin embryo. 
  • A boy with fever and whorl keratopathy. 
  • A chemokine expressed in lymphoid high endothelial venules promotes the adhesion and chemotaxis of naive T lymphocytes. 
  • A comparison of the community diversity of foliar fungal endophytes between seedling and adult loblolly pines (Pinus taeda). 
  • A comprehensive structure-function analysis of Arabidopsis SNI1 defines essential regions and transcriptional repressor activity. 
  • A cross-sectional survey of Plasmodium falciparum pfcrt mutant haplotypes in the Democratic Republic of Congo. 
  • A gene on chromosome 11q23 coding for a putative glucose- 6-phosphate translocase is mutated in glycogen-storage disease types Ib and Ic. 
  • A global reference for human genetic variation. 
  • A heteroduplex method for detection of targeted sub-populations of bacterial communities. 
  • A heterozygous IDH1R132H/WT mutation induces genome-wide alterations in DNA methylation. 
  • A human protein related to yeast Cdc6p. 
  • A molecular-based approach for examining responses of eukaryotes in microcosms to contaminant-spiked estuarine sediments. 
  • A multigene phylogenetic synthesis for the class Lecanoromycetes (Ascomycota): 1307 fungi representing 1139 infrageneric taxa, 317 genera and 66 families. 
  • A mutation in SLC24A1 implicated in autosomal-recessive congenital stationary night blindness. 
  • A mutation in the TRPC6 cation channel causes familial focal segmental glomerulosclerosis. 
  • A new NOS2 promoter polymorphism associated with increased nitric oxide production and protection from severe malaria in Tanzanian and Kenyan children. 
  • A new kinesin tree. 
  • A novel 2-oxoacid-dependent dioxygenase involved in the formation of the goiterogenic 2-hydroxybut-3-enyl glucosinolate and generalist insect resistance in Arabidopsis,. 
  • A novel alternative splice domain in zebrafish tenascin-C. 
  • A novel androgen-regulated gene, PMEPA1, located on chromosome 20q13 exhibits high level expression in prostate. 
  • A novel missense mutation of Wilms' Tumor 1 causes autosomal dominant FSGS. 
  • A nucleosome-guided map of transcription factor binding sites in yeast. 
  • A polymorphism within the promoter of the TGFβ1 gene is associated with radiation sensitivity using an objective radiologic endpoint. 
  • A rare penetrant mutation in CFH confers high risk of age-related macular degeneration. 
  • A strategy for the rapid identification of phosphorylation sites in the phosphoproteome. 
  • A tyrosine-phosphorylated protein that binds to an important regulatory region on the cool family of p21-activated kinase-binding proteins. 
  • Absence of mitochondrial progesterone receptor polymorphisms in women with spontaneous preterm birth. 
  • Absence of mutation in the beta- and gamma-synuclein genes in familial autosomal dominant Parkinson's disease. 
  • Actionable diagnosis of neuroleptospirosis by next-generation sequencing. 
  • Activated cAMP-response element-binding protein regulates neuronal expression of presenilin-1. 
  • Activating mutations in STIM1 and ORAI1 cause overlapping syndromes of tubular myopathy and congenital miosis. 
  • Activation of the plant mitochondrial alternative oxidase: insights from site-directed mutagenesis. 
  • Additional evidence that PGAP1 loss of function causes autosomal recessive global developmental delay and encephalopathy. 
  • Adenylate cyclase toxin (ACT) from Bordetella hinzii: characterization and differences from ACT of Bordetella pertussis. 
  • African strains of hepatitis E virus that are distinct from Asian strains. 
  • Allele-specific gene expression in a wild nonhuman primate population. 
  • Alleles of the yeast Pms1 mismatch-repair gene that differentially affect recombination- and replication-related processes. 
  • Allotetraploid Mimulus sookensis are highly interfertile despite independent origins. 
  • An STS-based map of the human genome. 
  • An autonomously self-assembling dendritic DNA nanostructure for target DNA detection. 
  • An information-theoretic method for the treatment of plural ancestry in phylogenetics. 
  • An integrated genomic analysis of human glioblastoma multiforme. 
  • An international effort towards developing standards for best practices in analysis, interpretation and reporting of clinical genome sequencing results in the CLARITY Challenge. 
  • An obligately photosynthetic bacterial anaerobe from a deep-sea hydrothermal vent. 
  • Analyses of pediatric isolates of Cryptococcus neoformans from South Africa. 
  • Analysis of 30 genes (355 SNPS) related to energy homeostasis for association with adiposity in European-American and Yup'ik Eskimo populations. 
  • Analysis of association at single nucleotide polymorphisms in the APOE region. 
  • Analysis of erythropoietin and erythropoietin receptor genes expression in cattle during acute infection with Trypanosoma congolense. 
  • Analysis of non-synonymous-coding variants of Parkinson's disease-related pathogenic and susceptibility genes in East Asian populations. 
  • Analysis of the indel at the ARMS2 3'UTR in age-related macular degeneration. 
  • Another surprise from the mitochondrial genome. 
  • Applying technologies towards safe and effective medicines. 
  • Aquacultured rainbow trout (Oncorhynchus mykiss) possess a large core intestinal microbiota that is resistant to variation in diet and rearing density. 
  • Are results of targeted gene sequencing ready to be used for clinical decision making for patients with acute myelogenous leukemia? 
  • Artifactual frame-shift p53 mutation at codon 249 detected with the Cyclist DNA sequencing method. 
  • Assessing disease severity in Pompe disease: the roles of a urinary glucose tetrasaccharide biomarker and imaging techniques. 
  • Association between 16S-23S internal transcribed spacer sequence groups of Mycobacterium avium complex and pulmonary disease. 
  • Association between novel PLCE1 variants identified in published esophageal cancer genome-wide association studies and risk of squamous cell carcinoma of the head and neck. 
  • Association of CD8(+) T lymphocyte repertoire spreading with the severity of DRESS syndrome. 
  • Association of genetic variants of O6-methylguanine-DNA methyltransferase with risk of lung cancer in non-Hispanic Whites. 
  • Association of levels of fasting glucose and insulin with rare variants at the chromosome 11p11.2-MADD locus: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study. 
  • Association of low-frequency and rare coding-sequence variants with blood lipids and coronary heart disease in 56,000 whites and blacks. 
  • Associations between antibiotic exposure during pregnancy, birth weight and aberrant methylation at imprinted genes among offspring. 
  • Automated constraint-based nucleotide sequence selection for DNA computation. 
  • Avian genomes. A flock of genomes. Introduction. 
  • Biogeography in deep time - What do phylogenetics, geology, and paleoclimate tell us about early platyrrhine evolution? 
  • Bisulfite pyrosequencing. 
  • Bisulfite sequencing of cloned alleles. 
  • Blood-based diagnostic testing for Pompe disease: consistency between GAA enzyme activity in dried blood spots and GAA gene sequencing results. 
  • Boranophosphates as mimics of natural phosphodiesters in DNA. 
  • Broad host range vectors for stable genomic library construction. 
  • Burkholderia glumae infection in an infant with chronic granulomatous disease. 
  • CA150, a nuclear protein associated with the RNA polymerase II holoenzyme, is involved in Tat-activated human immunodeficiency virus type 1 transcription. 
  • CC2D2A is mutated in Joubert syndrome and interacts with the ciliopathy-associated basal body protein CEP290. 
  • CCAAT/enhancer-binding protein alpha is required for transcription of the beta 3-adrenergic receptor gene during adipogenesis. 
  • CFTR haplotype analysis reveals genetic heterogeneity in the etiology of congenital bilateral aplasia of the vas deferens. 
  • CLPB mutations cause 3-methylglutaconic aciduria, progressive brain atrophy, intellectual disability, congenital neutropenia, cataracts, movement disorder. 
  • CRISPR-Cas9 epigenome editing enables high-throughput screening for functional regulatory elements in the human genome. 
  • Calreticulin chaperones regulate functional expression of vomeronasal type 2 pheromone receptors. 
  • Canine model and genomic structural organization of glycogen storage disease type Ia (GSD Ia). 
  • Carbonic anhydrase and CO2 sensing during Cryptococcus neoformans growth, differentiation, and virulence. 
  • Centromere reference models for human chromosomes X and Y satellite arrays. 
  • Characterization and prevalence of PITX2 microdeletions and mutations in Axenfeld-Rieger malformations. 
  • Characterization of a cholesterol response element (CRE) in the promoter of the cholesteryl ester transfer protein gene: functional role of the transcription factors SREBP-1a, -2, and YY1. 
  • Characterization of gene expression in human trabecular meshwork using single-pass sequencing of 1060 clones. 
  • Characterization of protective immune response elicited by a trimeric envelope protein from an Indian clade C HIV-1 isolate in rhesus macaques. 
  • Characterization of the intronic splicing silencers flanking FGFR2 exon IIIb. 
  • Characterization of the mouse transforming growth factor alpha gene: its expression during eyelid development and in waved 1 tissues. 
  • Characterization of the neural stem cell gene regulatory network identifies OLIG2 as a multifunctional regulator of self-renewal. 
  • Characterization of the variable-number tandem repeats in vrrA from different Bacillus anthracis isolates. 
  • Chiropteran types I and II interferon genes inferred from genome sequencing traces by a statistical gene-family assembler. 
  • Chromatin accessibility reveals insights into androgen receptor activation and transcriptional specificity. 
  • Chromosomal localization of gene for human glutamate receptor subunit-7. 
  • Circular viral DNA and anomalous junction sequence in PBMC of HIV-infected individuals with no detectable plasma HIV RNA. 
  • Clinical application of exome sequencing in undiagnosed genetic conditions. 
  • Clinical experience with array CGH: case presentations from nine months of practice. 
  • Clinical interpretation and implications of whole-genome sequencing. 
  • Clonal amplification and maternal-infant transmission of nevirapine-resistant HIV-1 variants in breast milk following single-dose nevirapine prophylaxis. 
  • Cloning and characterization of a mammalian prenyl protein-specific protease. 
  • Cloning and characterization of glioma BK, a novel BK channel isoform highly expressed in human glioma cells. 
  • Cloning and characterization of the nitrate reductase-encoding gene from Chlorella vulgaris: structure and identification of transcription start points and initiator sequences. 
  • Cloning and characterization of two splice variants of human phosphodiesterase 11A. 
  • Cloning of the promoter region of human endoglin, the target gene for hereditary hemorrhagic telangiectasia type 1. 
  • Coding Variation in ANGPTL4, LPL, and SVEP1 and the Risk of Coronary Disease. 
  • Compact organization of rRNA genes in the filamentous fungus Ashbya gossypii. 
  • Comparative analyses of clinical and environmental populations of Cryptococcus neoformans in Botswana. 
  • Comparative analysis of the primate X-inactivation center region and reconstruction of the ancestral primate XIST locus. 
  • Comparative evolutionary analysis of chalcone synthase and alcohol dehydrogenase loci in Arabidopsis, Arabis, and related genera (Brassicaceae). 
  • Comparative genomics and regulatory evolution: conservation and function of the Chs and Apetala3 promoters. 
  • Comparative genomics reveals insights into avian genome evolution and adaptation. 
  • Comparative physical and transcript maps of approximately 1 Mb around loop-tail, a gene for severe neural tube defects on distal mouse chromosome 1 and human chromosome 1q22-q23. 
  • Comparative population structure of two deep-sea hydrothermal-vent-associated decapods (Chorocaris sp. 2 and Munidopsis lauensis) from southwestern Pacific back-arc basins. 
  • Comparative tests of evolutionary trade-offs in a palinurid lobster acoustic system. 
  • Comparison of ribosomal DNA ITS regions among geographic isolates of Cenococcum geophilum. 
  • Complement factor H variant increases the risk of age-related macular degeneration. 
  • Complete genome sequencing and analysis of six enterovirus 71 strains with different clinical phenotypes. 
  • Complexity reduction in context-dependent DNA substitution models. 
  • Comprehensive, Integrative Genomic Analysis of Diffuse Lower-Grade Gliomas. 
  • Concessions of an alpha male? Cooperative defence and shared reproduction in multi-male primate groups. 
  • Consensus multi-locus sequence typing scheme for Cryptococcus neoformans and Cryptococcus gattii. 
  • Conservation of Endo16 expression in sea urchins despite evolutionary divergence in both cis and trans-acting components of transcriptional regulation. 
  • Conservation of Y-linked genes during human evolution revealed by comparative sequencing in chimpanzee. 
  • Contrasting quaternary histories in an ecologically divergent sister pair of low-dispersing intertidal fish (Xiphister) revealed by multilocus DNA analysis. 
  • Contribution of RPB2 to multilocus phylogenetic studies of the euascomycetes (Pezizomycotina, Fungi) with special emphasis on the lichen-forming Acarosporaceae and evolution of polyspory. 
  • Contribution of horizontal gene transfer to the evolution of Saccharomyces cerevisiae. 
  • Cowpox virus contains two copies of an early gene encoding a soluble secreted form of the type II TNF receptor. 
  • Cross-reactive HIV-1-neutralizing human monoclonal antibodies identified from a patient with 2F5-like antibodies. 
  • Cyanobacterial ribosomal RNA genes with multiple, endonuclease-encoding group I introns. 
  • DNA copy number evolution in Drosophila cell lines. 
  • DNA methylation at imprint regulatory regions in preterm birth and infection. 
  • DNA methylation profiling in the Carolina Breast Cancer Study defines cancer subclasses differing in clinicopathologic characteristics and survival. 
  • DNA sequence characterization and molecular evolution of MAT1 and MAT2 mating-type loci of the self-compatible ascomycete mold Neosartorya fischeri. 
  • DNA sequencing: detecting methylation with force. 
  • DNMT3b polymorphism and hereditary nonpolyposis colorectal cancer age of onset. 
  • DNase I sensitivity QTLs are a major determinant of human expression variation. 
  • Dating branches on the tree of life using DNA. 
  • Deciphering human immunodeficiency virus type 1 transmission and early envelope diversification by single-genome amplification and sequencing. 
  • Decreased expression of lysyl hydroxylase 2 (LH2) in skin fibroblasts from three Ehlers-Danlos patients does not result from mutations in either the coding or proximal promoter region of the LH2 gene. 
  • Deep divergence and rapid evolutionary rates in gut-associated Acetobacteraceae of ants. 
  • Depression in pregnancy, infant birth weight and DNA methylation of imprint regulatory elements. 
  • Destabilization of simple repetitive DNA sequences by transcription in yeast. 
  • Detailed analysis of allelic variation in the ABCA4 gene in age-related maculopathy. 
  • Determinants of CD4 independence for a human immunodeficiency virus type 1 variant map outside regions required for coreceptor specificity. 
  • Different transcript patterns in response to specialist and generalist herbivores in the wild Arabidopsis relative Boechera divaricarpa. 
  • Differential display of hepatic mRNA from killifish (Fundulus heteroclitus) inhabiting a Superfund estuary. 
  • Differential patterns of male and female mtDNA exchange across the Atlantic Ocean in the blue mussel, Mytilus edulis. 
  • Differentially methylated regions of imprinted genes in prenatal, perinatal and postnatal human tissues. 
  • Digital microfluidic chips for chemical and biological applications. 
  • Disruption of syntaxin-mediated protein interactions blocks neurotransmitter secretion. 
  • Distinct Epigenetic Effects of Tobacco Smoking in Whole Blood and among Leukocyte Subtypes. 
  • Distribution and diversity of planktonic fungi in the West Pacific Warm Pool. 
  • Distribution of WDR36 DNA sequence variants in patients with primary open-angle glaucoma. 
  • Distribution of optineurin sequence variations in an ethnically diverse population of low-tension glaucoma patients from the United States. 
  • Diversification before the most recent glaciation in Balanus glandula. 
  • Diversity and detection of nitrate assimilation genes in marine bacteria. 
  • Diversity and host range of foliar fungal endophytes: are tropical leaves biodiversity hotspots? 
  • Diversity and phylogenetic affinities of foliar fungal endophytes in loblolly pine inferred by culturing and environmental PCR. 
  • Do asexual polyploid lineages lead short evolutionary lives? A case study from the fern genus Astrolepis. 
  • Dosage changes of a segment at 17p13.1 lead to intellectual disability and microcephaly as a result of complex genetic interaction of multiple genes. 
  • Dramatic mitochondrial gene rearrangements in the hermit crab Pagurus longicarpus (Crustacea, anomura). 
  • Drosophila ORC localizes to open chromatin and marks sites of cohesin complex loading. 
  • Dual infection with Ehrlichia chaffeensis and a spotted fever group rickettsia: a case report. 
  • Early-onset stroke and vasculopathy associated with mutations in ADA2. 
  • Efficient Genome-Wide Sequencing and Low-Coverage Pedigree Analysis from Noninvasively Collected Samples. 
  • Elevated MAL expression is accompanied by promoter hypomethylation and platinum resistance in epithelial ovarian cancer. 
  • Emergence of Epidemic Dengue-1 Virus in the Southern Province of Sri Lanka. 
  • Enhanced potency of a broadly neutralizing HIV-1 antibody in vitro improves protection against lentiviral infection in vivo. 
  • Epigenetic detection of human chromosome 14 uniparental disomy. 
  • Essential light chain of Drosophila nonmuscle myosin II. 
  • Evaluation and optimisation of indel detection workflows for ion torrent sequencing of the BRCA1 and BRCA2 genes. 
  • Evaluation of Lipin 2 as a candidate gene for autosomal dominant 1 high-grade myopia. 
  • Evidence for GC-biased gene conversion as a driver of between-lineage differences in avian base composition. 
  • Evidence for reciprocal origins in Polypodium hesperium (Polypodiaceae): a fern model system for investigating how multiple origins shape allopolyploid genomes. 
  • Evidence of mRNA-mediated intron loss in the human-pathogenic fungus Cryptococcus neoformans. 
  • Evidence of sexual recombination among Cryptococcus neoformans serotype A isolates in sub-Saharan Africa. 
  • Evidence-ranked motif identification. 
  • Evolution of Pleopsidium (lichenized Ascomycota) S943 group I introns and the phylogeography of an intron-encoded putative homing endonuclease. 
  • Evolution of drug-resistant viral populations during interruption of antiretroviral therapy. 
  • Evolution of flux control in the glucosinolate pathway in Arabidopsis thaliana. 
  • Evolution of genes and genomes on the Drosophila phylogeny. 
  • Evolution of relative synonymous codon usage in Human Immunodeficiency Virus type-1. 
  • Evolutionary analysis of the well characterized endo16 promoter reveals substantial variation within functional sites. 
  • Evolutionary relationships within the Neotropical, eusporangiate fern genus Danaea (Marattiaceae). 
  • Examination of type IV pilus expression and pilus-associated phenotypes in Kingella kingae clinical isolates. 
  • Exclusion of lumican and fibromodulin as candidate genes in MYP3 linked high grade myopia. 
  • Exome analysis of two limb-girdle muscular dystrophy families: mutations identified and challenges encountered. 
  • Exome sequencing followed by large-scale genotyping fails to identify single rare variants of large effect in idiopathic generalized epilepsy. 
  • Exome sequencing followed by large-scale genotyping suggests a limited role for moderately rare risk factors of strong effect in schizophrenia. 
  • Exome sequencing identifies distinct mutational patterns in liver fluke-related and non-infection-related bile duct cancers. 
  • Exome sequencing identifies highly recurrent MED12 somatic mutations in breast fibroadenoma. 
  • Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma. 
  • Exome sequencing in amyotrophic lateral sclerosis identifies risk genes and pathways. 
  • Exome sequencing of gastric adenocarcinoma identifies recurrent somatic mutations in cell adhesion and chromatin remodeling genes. 
  • Exome sequencing of liver fluke-associated cholangiocarcinoma. 
  • Exome-wide Sequencing Shows Low Mutation Rates and Identifies Novel Mutated Genes in Seminomas. 
  • Expansion of somatically reverted memory CD8+ T cells in patients with X-linked lymphoproliferative disease caused by selective pressure from Epstein-Barr virus. 
  • Explicit DNase sequence bias modeling enables high-resolution transcription factor footprint detection. 
  • Expressed sequence tag analysis in Cycas, the most primitive living seed plant. 
  • Expression in aneuploid Drosophila S2 cells. 
  • Expression of a chemokine by ciliary body epithelium in horses with naturally occurring recurrent uveitis and in cultured ciliary body epithelial cells. 
  • Expression of the protein tyrosine phosphatase, phosphatase of regenerating liver 1, in the outer segments of primate cone photoreceptors. 
  • Expression profile of an androgen regulated prostate specific homeobox gene NKX3.1 in primary prostate cancer. 
  • Extensive chloroplast haplotype variation indicates Pleistocene hybridization and radiation of North American Arabis drummondii, A. x divaricarpa, and A. holboellii (Brassicaceae). 
  • F-Seq: a feature density estimator for high-throughput sequence tags. 
  • Fanconi anemia gene variants in therapy-related myeloid neoplasms. 
  • Fast Dissemination of New HIV-1 CRF02/A1 Recombinants in Pakistan. 
  • Faster algorithms for optimal multiple sequence alignment based on pairwise comparisons. 
  • Finding regulatory DNA motifs using alignment-free evolutionary conservation information. 
  • Flexible use of high-density oligonucleotide arrays for single-nucleotide polymorphism discovery and validation. 
  • Focused evolution of HIV-1 neutralizing antibodies revealed by structures and deep sequencing. 
  • Forward genetic approaches in Chlamydia trachomatis. 
  • Frequent detection of codon 877 mutation in the androgen receptor gene in advanced prostate cancers. 
  • Functional consequences of natural sequence variation in the activation domain of HIV-1 Rev. 
  • Functionally compromised CHD7 alleles in patients with isolated GnRH deficiency. 
  • Fungal Community Responses to Past and Future Atmospheric CO2 Differ by Soil Type. 
  • Fungal community analysis by large-scale sequencing of environmental samples. 
  • Genetic Drivers of Kidney Defects in the DiGeorge Syndrome. 
  • Genetic analysis of the requirements for SOS induction by nalidixic acid in Escherichia coli. 
  • Genetic and functional association of FAM5C with myocardial infarction. 
  • Genetic and neutralization properties of subtype C human immunodeficiency virus type 1 molecular env clones from acute and early heterosexually acquired infections in Southern Africa. 
  • Genetic diagnosis of autism spectrum disorders: the opportunity and challenge in the genomics era. 
  • Genetic diversity in the Mycobacterium tuberculosis complex based on variable numbers of tandem DNA repeats. 
  • Genetic diversity of the Cryptococcus species complex suggests that Cryptococcus gattii deserves to have varieties. 
  • Genetic isolation between two recently diverged populations of a symbiotic fungus. 
  • Genetic plasticity of V genes under somatic hypermutation: statistical analyses using a new resampling-based methodology. 
  • Genetic screen of African Americans with Fuchs endothelial corneal dystrophy. 
  • Genetic structure and genealogy in the Sphagnum subsecundum complex (Sphagnaceae: Bryophyta). 
  • Genetic typing of HIV-2 from a Senegalese/German heterosexual transmission. 
  • Genetic variation in the 3' non-coding region of dengue viruses. 
  • Genetic variation in the odorant receptor OR2J3 is associated with the ability to detect the "grassy" smelling odor, cis-3-hexen-1-ol. 
  • Genome Evolution and Innovation across the Four Major Lineages of Cryptococcus gattii. 
  • Genome engineering: the next genomic revolution. 
  • Genome structure of a Saccharomyces cerevisiae strain widely used in bioethanol production. 
  • Genome wide analyses reveal little evidence for adaptive evolution in many plant species. 
  • Genome-wide mapping of DNase hypersensitive sites using massively parallel signature sequencing (MPSS). 
  • Genome-wide mutagenesis of influenza virus reveals unique plasticity of the hemagglutinin and NS1 proteins. 
  • Genome-wide prediction of imprinted murine genes. 
  • Genome-wide specificity of DNA binding, gene regulation, and chromatin remodeling by TALE- and CRISPR/Cas9-based transcriptional activators. 
  • Genomes of Ashbya fungi isolated from insects reveal four mating-type loci, numerous translocations, lack of transposons, and distinct gene duplications. 
  • Genomewide investigation of adaptation to harmful algal blooms in common bottlenose dolphins (Tursiops truncatus). 
  • Genomic analysis of diffuse intrinsic pontine gliomas identifies three molecular subgroups and recurrent activating ACVR1 mutations. 
  • Genomic and genetic definition of a functional human centromere. 
  • Genomic characterization of large heterochromatic gaps in the human genome assembly. 
  • Genomic organization, expression, and localization of murine Ran-binding protein 2 (RanBP2) gene. 
  • Genomic signatures of near-extinction and rebirth of the crested ibis and other endangered bird species. 
  • Genomic structure and organization of the high grade Myopia-2 locus (MYP2) critical region: mutation screening of 9 positional candidate genes. 
  • Genomic sweeping for hypermethylated genes. 
  • Genomics and Transcriptomics Analyses of the Oil-Accumulating Basidiomycete Yeast Trichosporon oleaginosus: Insights into Substrate Utilization and Alternative Evolutionary Trajectories of Fungal Mating Systems. 
  • Genomics and genetics of human and primate y chromosomes. 
  • Genotypic analysis of tumor suppressor genes PTEN/MMAC1 and p53 in head and neck squamous cell carcinomas. 
  • Genotypic diversity of anaerobic isolates from bloodstream infections. 
  • Genotypic diversity of coagulase-negative staphylococci causing endocarditis: a global perspective. 
  • Germline and somatic SMARCA4 mutations characterize small cell carcinoma of the ovary, hypercalcemic type. 
  • Global genetic diversity of human metapneumovirus fusion gene. 
  • Global patterns in peatmoss biodiversity. 
  • Glycogen-branching enzyme deficiency leads to abnormal cardiac development: novel insights into glycogen storage disease IV. 
  • Group-I intron family in the nuclear ribosomal RNA small subunit genes of Cenococcum geophilum isolates. 
  • HIV quasispecies and resampling. 
  • HIV type 1 from a patient with baseline resistance to CCR5 antagonists uses drug-bound receptor for entry. 
  • Heritable individual-specific and allele-specific chromatin signatures in humans. 
  • Heterochromatic sequences in a Drosophila whole-genome shotgun assembly. 
  • Heterogeneous polymerase fidelity and mismatch repair bias genome variation and composition. 
  • Heterothallic mating in Mucor irregularis and first isolate of the species outside of Asia. 
  • High frequency of mutations of the PIK3CA gene in human cancers. 
  • High genetic diversity and population differentiation in Boechera fecunda, a rare relative of Arabidopsis. 
  • High throughput detection of M6P/IGF2R intronic hypermethylation and LOH in ovarian cancer. 
  • High-resolution mapping and characterization of open chromatin across the genome. 
  • Highly active zinc-finger nucleases by extended modular assembly. 
  • Historical effects on beta diversity and community assembly in Amazonian trees. 
  • Host lifestyle affects human microbiota on daily timescales. 
  • Host-symbiont stability and fast evolutionary rates in an ant-bacterium association: cospeciation of camponotus species and their endosymbionts, candidatus blochmannia. 
  • Human and mouse alpha-synuclein genes: comparative genomic sequence analysis and identification of a novel gene regulatory element. 
  • Human disturbance causes the formation of a hybrid swarm between two naturally sympatric fish species. 
  • Human immunodeficiency virus type 1 protease genotype predicts immune and viral responses to combination therapy with protease inhibitors (PIs) in PI-naive patients. 
  • Human metapneumovirus, Peru. 
  • Human promoters are intrinsically directional. 
  • Human syndromes of immunodeficiency and dysregulation are characterized by distinct defects in T-cell receptor repertoire development. 
  • IGF2R genetic variants, circulating IGF2 concentrations and colon cancer risk in African Americans and Whites. 
  • Identification and characterization of K12 (SECTM1), a novel human gene that encodes a Golgi-associated protein with transmembrane and secreted isoforms. 
  • Identification and characterization of cell type-specific and ubiquitous chromatin regulatory structures in the human genome. 
  • Identification and developmental expression of two activin receptors in baboon lung. 
  • Identification of 28 novel mutations in the Bardet-Biedl syndrome genes: the burden of private mutations in an extensively heterogeneous disease. 
  • Identification of HIV-1 genitourinary tract compartmentalization by analyzing the env gene sequences in urine. 
  • Identification of a copper transporter family in Arabidopsis thaliana. 
  • Identification of a region of genetic variability among Bacillus anthracis strains and related species. 
  • Identification of amino acid substitutions associated with neutralization phenotype in the human immunodeficiency virus type-1 subtype C gp120. 
  • Identification of core promoter modules in Drosophila and their application in accurate transcription start site prediction. 
  • Identification of genes expressed in a human scleral cDNA library. 
  • Identification of new mamu-DRB alleles using DGGE and direct sequencing. 
  • Identification of ongoing human immunodeficiency virus type 1 (HIV-1) replication in residual viremia during recombinant HIV-1 poxvirus immunizations in patients with clinically undetectable viral loads on durable suppressive highly active antiretroviral therapy. 
  • Identification of the mating-type (MAT) locus that controls sexual reproduction of Blastomyces dermatitidis. 
  • Identification of the sequences within the human complement 3 promoter required for estrogen responsiveness provides insight into the mechanism of tamoxifen mixed agonist activity. 
  • Identifying multiple origins of polyploid taxa: a multilocus study of the hybrid cloak fern (Astrolepis integerrima; Pteridaceae). 
  • Immunization with recombinant HLA classes I and II, HIV-1 gp140, and SIV p27 elicits protection against heterologous SHIV infection in rhesus macaques. 
  • Impact of genotypic resistance testing on physician selection of antiretroviral therapy. 
  • Implementing a cumulative supermatrix approach for a comprehensive phylogenetic study of the Teloschistales (Pezizomycotina, Ascomycota). 
  • Importance sampling for the infinite sites model. 
  • Imprinted expression of the canine IGF2R, in the absence of an anti-sense transcript or promoter methylation. 
  • Imprinting of PEG3, the human homologue of a mouse gene involved in nurturing behavior. 
  • In-depth analysis of Kaposi's sarcoma-associated herpesvirus microRNA expression provides insights into the mammalian microRNA-processing machinery. 
  • Inbreeding depression in non-human primates: a historical review of methods used and empirical data. 
  • Increased rectal microbial richness is associated with the presence of colorectal adenomas in humans. 
  • Independent ancient polyploidy events in the sister families Brassicaceae and Cleomaceae. 
  • Informative priors based on transcription factor structural class improve de novo motif discovery. 
  • Inhibition of a yeast LTR retrotransposon by human APOBEC3 cytidine deaminases. 
  • Initial antibodies binding to HIV-1 gp41 in acutely infected subjects are polyreactive and highly mutated. 
  • Initial sequencing and analysis of the human genome. 
  • Initial sequencing and comparative analysis of the mouse genome. 
  • Integrating chemical mutagenesis and whole-genome sequencing as a platform for forward and reverse genetic analysis of Chlamydia. 
  • Interrogation of individual intratumoral B lymphocytes from lung cancer patients for molecular target discovery. 
  • Intraspecific phylogenetic congruence among multiple symbiont genomes. 
  • Intraspecific variation in symbiont genomes: bottlenecks and the aphid-buchnera association. 
  • Invasive aspergillosis due to Neosartorya udagawae. 
  • Invasive disease caused by nontuberculous mycobacteria, Tanzania. 
  • Investigating deep phylogenetic relationships among cyanobacteria and plastids by small subunit rRNA sequence analysis. 
  • Is the aneuploid chromosome in an apomictic Boechera holboellii a genuine B chromosome? 
  • Isolation and characterization of a new chemokine receptor gene, the putative chicken CXCR1. 
  • Isolation and characterization of the CYP71D16 trichome-specific promoter from Nicotiana tabacum L. 
  • Isolation and initial characterization of the 5' flanking region of the human and murine cyclic guanosine monophosphate-phosphodiesterase beta-subunit genes. 
  • Isolation and initial characterization of the BRCA2 promoter. 
  • Isolation of genes negatively or positively co-expressed with human recombination activating gene 1 (RAG1) by differential display PCR (DD RT-PCR). 
  • Lack of association of mutations in optineurin with disease in patients with adult-onset primary open-angle glaucoma. 
  • Lagenidium sp. ocular infection mimicking ocular pythiosis. 
  • Landscape position influences microbial composition and function via redistribution of soil water across a watershed. 
  • Large scale association analysis for identification of genes underlying premature coronary heart disease: cumulative perspective from analysis of 111 candidate genes. 
  • Large-scale identification and analysis of genome-wide single-nucleotide polymorphisms for mapping in Arabidopsis thaliana. 
  • Large-scale identification, mapping, and genotyping of single-nucleotide polymorphisms in the human genome. 
  • Leptotrichia endocarditis: report of two cases from the International Collaboration on Endocarditis (ICE) database and review of previous cases. 
  • Life, diversity and the pursuit of haplotypes. 
  • Local replication of simian immunodeficiency virus in the breast milk compartment of chronically-infected, lactating rhesus monkeys. 
  • Loss of FHIT expression in cervical carcinoma cell lines and primary tumors. 
  • Loss of Function Mutations in NNT Are Associated With Left Ventricular Noncompaction. 
  • Low frequency of paleoviral infiltration across the avian phylogeny. 
  • Low level exposure to the flame retardant BDE-209 reduces thyroid hormone levels and disrupts thyroid signaling in fathead minnows. 
  • Low prevalence of myocilin mutations in an African American population with primary open-angle glaucoma. 
  • Lysis and lysis inhibition in bacteriophage T4: rV mutations reside in the holin t gene. 
  • MSIseq: Software for Assessing Microsatellite Instability from Catalogs of Somatic Mutations. 
  • MTL genotypes, phenotypic switching, and susceptibility profiles of Candida parapsilosis species group compared to Lodderomyces elongisporus. 
  • Making sense of microarrays. 
  • Malaria severity and human nitric oxide synthase type 2 (NOS2) promoter haplotypes. 
  • Maternal microchimerism in Hirschsprung's disease. 
  • Mating-type locus of Cryptococcus neoformans: a step in the evolution of sex chromosomes. 
  • Matrix metalloproteinase-1 gene promoter polymorphism and risk of ovarian cancer. 
  • Measuring spatial preferences at fine-scale resolution identifies known and novel cis-regulatory element candidates and functional motif-pair relationships. 
  • Mesotheliomas induced in rats by the fibrous mineral erionite are independent from p53 alterations. 
  • Microbiome of the upper troposphere: species composition and prevalence, effects of tropical storms, and atmospheric implications. 
  • Microsatellite analysis of genetic diversity among clinical and nonclinical Saccharomyces cerevisiae isolates suggests heterozygote advantage in clinical environments. 
  • Misidentification of Neosartorya pseudofischeri as Aspergillus fumigatus in a lung transplant patient. 
  • Missing genetic risk in neural tube defects: can exome sequencing yield an insight? 
  • Mistaken Identity: Another Bias in the Use of Relative Genetic Divergence Measures for Detecting Interspecies Introgression. 
  • Mitochondrial NADP(H) deficiency due to a mutation in NADK2 causes dienoyl-CoA reductase deficiency with hyperlysinemia. 
  • Mobile elements and mitochondrial genome expansion in the soil fungus and potato pathogen Rhizoctonia solani AG-3. 
  • Modeling the evolution of regulatory elements by simultaneous detection and alignment with phylogenetic pair HMMs. 
  • Molecular analysis of HLA-B35 alleles and their relationship to HLA-B15 alleles. 
  • Molecular analysis of adenovirus isolates from vaccinated and unvaccinated young adults. 
  • Molecular analysis of the Cryptococcus neoformans ADE2 gene, a selectable marker for transformation and gene disruption. 
  • Molecular basis of a novel adaptation to hypoxic-hypercapnia in a strictly fossorial mole. 
  • Molecular characterization of CLPT1, a SEC4-like Rab/GTPase of the phytopathogenic fungus Colletotrichum lindemuthianum which is regulated by the carbon source. 
  • Molecular cloning and characterization of Atp6v1b1, the murine vacuolar H+ -ATPase B1-subunit. 
  • Molecular genetic testing and the future of clinical genomics. 
  • Molecular identification of Aspergillus species collected for the Transplant-Associated Infection Surveillance Network. 
  • Molecular identification, cloning and characterization of transmitted/founder HIV-1 subtype A, D and A/D infectious molecular clones. 
  • Molecular phylogeography and cryptic speciation in the mosses, Mielichhoferia elongata and M. mielichhoferiana (Bryaceae). 
  • Molecular recognition of ketamine by a subset of olfactory G protein-coupled receptors. 
  • Molecular typing of clinical adenovirus specimens by an algorithm which permits detection of adenovirus coinfections and intermediate adenovirus strains. 
  • Most environmental isolates of Cryptococcus neoformans var. grubii (serotype A) are not lethal for mice. 
  • Multicenter evaluation of the Vitek 2 anaerobe and Corynebacterium identification card. 
  • Multicenter evaluation of the new Vitek 2 Neisseria-Haemophilus identification card. 
  • Multidonor analysis reveals structural elements, genetic determinants, and maturation pathway for HIV-1 neutralization by VRC01-class antibodies. 
  • Multilocus sequence typing reveals three genetic subpopulations of Cryptococcus neoformans var. grubii (serotype A), including a unique population in Botswana. 
  • Multiple origins of hybrid strains of Cryptococcus neoformans with serotype AD. 
  • Multiple potential regulatory elements in the 5' flanking region of the human alpha 1a-adrenergic receptor. 
  • Multiplexed short tandem repeat polymorphisms of the Weber 8A set of markers using tailed primers and infrared fluorescence detection. 
  • Multivariate analysis of associations of 42 genes in ADHD, ODD and conduct disorder. 
  • Murine noroviruses comprising a single genogroup exhibit biological diversity despite limited sequence divergence. 
  • Mutation and overexpression of p53 in early-stage epithelial ovarian cancer. 
  • Mutation exposed: a neutral explanation for extreme base composition of an endosymbiont genome. 
  • Mutation in TECPR2 reveals a role for autophagy in hereditary spastic paraparesis. 
  • Mutation of TBCE causes hypoparathyroidism-retardation-dysmorphism and autosomal recessive Kenny-Caffey syndrome. 
  • Mutation screening of patients with Leber Congenital Amaurosis or the enhanced S-Cone Syndrome reveals a lack of sequence variations in the NRL gene. 
  • Mutational landscapes of tongue carcinoma reveal recurrent mutations in genes of therapeutic and prognostic relevance. 
  • Mutations in CIC and FUBP1 contribute to human oligodendroglioma. 
  • Mutations in DDX3X Are a Common Cause of Unexplained Intellectual Disability with Gender-Specific Effects on Wnt Signaling. 
  • Mutations in NGLY1 cause an inherited disorder of the endoplasmic reticulum-associated degradation pathway. 
  • Mutations in RAD21 disrupt regulation of APOB in patients with chronic intestinal pseudo-obstruction. 
  • Mutations in RSPH1 cause primary ciliary dyskinesia with a unique clinical and ciliary phenotype. 
  • Mutations in SCO2 are associated with autosomal-dominant high-grade myopia. 
  • Mutations in TNK2 in severe autosomal recessive infantile onset epilepsy. 
  • Mutations in a gene encoding a novel protein containing a phosphotyrosine-binding domain cause type 2 cerebral cavernous malformations. 
  • Mutations in the endothelin receptor type A cause mandibulofacial dysostosis with alopecia. 
  • Mutations of the Ki-ras oncogene in endometrial carcinoma. 
  • Myotilin is mutated in limb girdle muscular dystrophy 1A. 
  • NPAS3 is a trachealess homolog critical for lung development and homeostasis. 
  • Natural IgM is produced by CD5- plasma cells that occupy a distinct survival niche in bone marrow. 
  • Nature and distribution of large sequence polymorphisms in Saccharomyces cerevisiae. 
  • New Member of the V1V2-Directed CAP256-VRC26 Lineage That Shows Increased Breadth and Exceptional Potency. 
  • New techniques for DNA sequence classification. 
  • Newborns of obese parents have altered DNA methylation patterns at imprinted genes. 
  • Next-generation genotyping of hypervariable loci in many individuals of a non-model species: technical and theoretical implications. 
  • Next-generation sequencing of the human olfactory receptors. 
  • No evidence for maternal-fetal microchimerism in infantile hemangioma: a molecular genetic investigation. 
  • Nonmuscle myosin II generates forces that transmit tension and drive contraction in multiple tissues during dorsal closure. 
  • Novel Insights into Chromosome Evolution in Birds, Archosaurs, and Reptiles. 
  • Novel associations of UDP-glucuronosyltransferase 2B gene variants with prostate cancer risk in a multiethnic study. 
  • Novel forms of structural integration between microbes and a hydrothermal vent gastropod from the Indian Ocean. 
  • Nucleotide pool imbalance and adenosine deaminase deficiency induce alterations of N-region insertions during V(D)J recombination. 
  • OTX2 mutations contribute to the otocephaly-dysgnathia complex. 
  • Of urchins and men: evolution of an alternative splicing unit in fibroblast growth factor receptor genes. 
  • Olfactory Receptor Subgenomes Linked with Broad Ecological Adaptations in Sauropsida. 
  • Oncogenic CARD11 mutations in human diffuse large B cell lymphoma. 
  • One nutritional symbiosis begat another: phylogenetic evidence that the ant tribe Camponotini acquired Blochmannia by tending sap-feeding insects. 
  • Ontogenetic Differences in Dietary Fat Influence Microbiota Assembly in the Zebrafish Gut. 
  • Open chromatin defined by DNaseI and FAIRE identifies regulatory elements that shape cell-type identity. 
  • Organellar phylogenomics of an emerging model system: Sphagnum (peatmoss). 
  • Organization and evolution of an alpha satellite DNA subset shared by human chromosomes 13 and 21. 
  • Organization and evolutionary trajectory of the mating type (MAT) locus in dermatophyte and dimorphic fungal pathogens. 
  • Organization of the MASP2 locus and its expression profile in mouse and rat. 
  • Origin and evolution of HIV-1 in breast milk determined by single-genome amplification and sequencing. 
  • Outbreak of febrile respiratory illness associated with human adenovirus type 14p1 in Gansu Province, China. 
  • Ovarian cycling and reproductive state shape the vaginal microbiota in wild baboons. 
  • POWRS: position-sensitive motif discovery. 
  • Paired-end analysis of transcription start sites in Arabidopsis reveals plant-specific promoter signatures. 
  • Parallel acceleration of evolutionary rates in symbiont genes underlying host nutrition. 
  • Partial resistance to infection by R5X4 primary HIV type 1 isolates in an exposed-uninfected individual homozygous for CCR5 32-base pair deletion. 
  • Patterns of gut bacterial colonization in three primate species. 
  • Patterns of nucleotide diversity in two species of Mimulus are affected by mating system and asymmetric introgression. 
  • Peatmoss (Sphagnum) diversification associated with Miocene Northern Hemisphere climatic cooling? 
  • Performance assessment of promoter predictions on ENCODE regions in the EGASP experiment. 
  • Phospholipid-binding protein Cts1 controls septation and functions coordinately with calcineurin in Cryptococcus neoformans. 
  • Phylogenetic analyses of eurotiomycetous endophytes reveal their close affinities to Chaetothyriales, Eurotiales, and a new order - Phaeomoniellales. 
  • Phylogenetic analyses of morphological evolution in the gametophyte and sporophyte generations of the moss order Hookeriales (Bryopsida). 
  • Phylogenetic analysis of feline immunodeficiency virus in feral and companion domestic cats of New Zealand. 
  • Phylogenetic analysis of viridans group streptococci causing endocarditis. 
  • Phylogenetic comparison of protein-coding versus ribosomal RNA-coding sequence data: a case study of the Lecanoromycetes (Ascomycota). 
  • Phylogenetic evidence of a rapid radiation of pleurocarpous mosses (Bryophyta). 
  • Phylogenetic reassessment of the Teloschistaceae (lichen-forming Ascomycota, Lecanoromycetes). 
  • Phylogenetic relationships of Rhizoctonia fungi within the Cantharellales. 
  • Phylogenetic relationships, host affinity, and geographic structure of boreal and arctic endophytes from three major plant lineages. 
  • Phylogenetic relationships, morphological incongruence, and geographic speciation in the fontinalaceae (Bryophyta). 
  • Phylogeny and biogeography of the American live oaks (Quercus subsection Virentes): a genomic and population genetics approach. 
  • Phylogeny of twenty Thermus isolates constructed from 16S rRNA gene sequence data. 
  • Phylogeny, biogeography, and processes of molecular differentiation in Quercus subgenus Quercus (Fagaceae). 
  • Phylogeography of the Solanaceae-infecting Basidiomycota fungus Rhizoctonia solani AG-3 based on sequence analysis of two nuclear DNA loci. 
  • Physical maps for genome analysis of serotype A and D strains of the fungal pathogen Cryptococcus neoformans. 
  • Picoliter DNA sequencing chemistry on an electrowetting-based digital microfluidic platform. 
  • Plant host and soil origin influence fungal and bacterial assemblages in the roots of woody plants. 
  • Polymorphisms in Fibronectin Binding Proteins A and B among Staphylococcus aureus Bloodstream Isolates Are Not Associated with Arthroplasty Infection. 
  • Population history in Arabidopsis halleri using multilocus analysis. 
  • Positive selection driving diversification in plant secondary metabolism. 
  • Positive selection on MMP3 regulation has shaped heart disease risk. 
  • Practical considerations in the clinical application of whole-exome sequencing. 
  • Precise localization of the FHIT gene to the common fragile site at 3p14.2 (FRA3B) and characterization of homozygous deletions within FRA3B that affect FHIT transcription in tumor cell lines. 
  • Precise spatio-temporal regulation of the anthocyanin biosynthetic pathway leads to petal spot formation in Clarkia gracilis (Onagraceae). 
  • Predicting demographic group structures based on DNA sequence data. 
  • Pregnancy without progesterone in horses defines a second endogenous biopotent progesterone receptor agonist, 5α-dihydroprogesterone. 
  • Preparation, resonance assignment, and preliminary dynamics characterization of residue specific 13C/15N-labeled elongated DNA for the study of sequence-directed dynamics by NMR. 
  • Prevalence and characterization of metallo-beta-lactamases in clinical isolates of pseudomonas aeruginosa. 
  • Prevalence of deleterious ATM germline mutations in gastric cancer patients. 
  • Promoter prediction on a genomic scale--the Adh experience. 
  • Purification, cDNA sequence, and tissue distribution of rat uroguanylin. 
  • Quantitating the multiplicity of infection with human immunodeficiency virus type 1 subtype C reveals a non-poisson distribution of transmitted variants. 
  • RGSZ1, a Gz-selective regulator of G protein signaling whose action is sensitive to the phosphorylation state of Gzalpha. 
  • Rapid mapping of insertional mutations to probe cell wall regulation in Cryptococcus neoformans. 
  • Rare codons regulate KRas oncogenesis. 
  • Rare variants in CFI, C3 and C9 are associated with high risk of advanced age-related macular degeneration. 
  • Reading, writing, and modulating genetic information with boranophosphate mimics of nucleotides, DNA, and RNA. 
  • Realizing the opportunities of genomics in health care. 
  • Recombination between palindromes P5 and P1 on the human Y chromosome causes massive deletions and spermatogenic failure. 
  • Reconstructing the temporal ordering of biological samples using microarray data. 
  • Regional clustering of shared neutralization determinants on primary isolates of clade C human immunodeficiency virus type 1 from South Africa. 
  • Regulation of basement membrane-reactive B cells in BXSB, (NZBxNZW)F1, NZB, and MRL/lpr lupus mice. 
  • Regulation of cytochrome c oxidase subunit 1 (COX1) expression in Cryptococcus neoformans by temperature and host environment. 
  • Relaxed constraint and evolutionary rate variation between basic helix-loop-helix floral anthocyanin regulators in Ipomoea. 
  • Remarkably little variation in proteins encoded by the Y chromosome's single-copy genes, implying effective purifying selection. 
  • Removal of polymerase-produced mutant sequences from PCR products. 
  • Repeated phenotypic changes highlight molecular targets of convergent evolution. 
  • Replication of the recessive STBMS1 locus but with dominant inheritance. 
  • Report and abstracts of the sixth international workshop on human chromosome 1 mapping 2000. Iowa City, Iowa, USA. 30 September-3 October 2000. 
  • Report and abstracts of the third international workshop on human chromosome 1 mapping 1997. 
  • Report of the fifth international workshop on human chromosome 1 mapping 1999. 
  • Resistance mechanisms for the Bruton's tyrosine kinase inhibitor ibrutinib. 
  • Resistance mutations at the lipid substrate binding site of Plasmodium falciparum protein farnesyltransferase. 
  • Reversion and T cell escape mutations compensate the fitness loss of a CD8+ T cell escape mutant in their cognate transmitted/founder virus. 
  • Revolution and renaissance. 
  • RoBo-1, a novel member of the urokinase plasminogen activator receptor/CD59/Ly-6/snake toxin family selectively expressed in rat bone and growth plate cartilage. 
  • Role of Cdc42p in pheromone-stimulated signal transduction in Saccharomyces cerevisiae. 
  • Role of Escherichia coli DNA polymerase I in conferring viability upon the dnaN159 mutant strain. 
  • SCAR, a WASP-related protein, isolated as a suppressor of receptor defects in late Dictyostelium development. 
  • SNPselector: a web tool for selecting SNPs for genetic association studies. 
  • SVA: software for annotating and visualizing sequenced human genomes. 
  • Sakacin P non-producing Lactobacillus sakei strains contain homologues of the sakacin P gene cluster. 
  • Screening the human exome: a comparison of whole genome and whole transcriptome sequencing. 
  • Selective sweeps and intercontinental migration in the cosmopolitan moss Ceratodon purpureus (Hedw.) Brid. 
  • SeqSIMLA2: simulating correlated quantitative traits accounting for shared environmental effects in user-specified pedigree structure. 
  • Sequence analysis of a cDNA for lysyl hydroxylase isolated from human skin fibroblasts from a normal donor: differences from human placental lysyl hydroxylase cDNA. 
  • Sequence features of DNA binding sites reveal structural class of associated transcription factor. 
  • Sequence specificity incompletely defines the genome-wide occupancy of Myc. 
  • Sequence variants in the transforming growth beta-induced factor (TGIF) gene are not associated with high myopia. 
  • Sequence-based differentiation of strains in the Mycobacterium avium complex. 
  • Sequencing analysis of the ATOH7 gene in individuals with optic nerve hypoplasia. 
  • Sequencing and analysis of genomic fragments from the NF1 locus. 
  • Sequencing studies in human genetics: design and interpretation. 
  • Sequencing the mouse Y chromosome reveals convergent gene acquisition and amplification on both sex chromosomes. 
  • Short communication: HIV type 1 subtype C variants transmitted through the bottleneck of breastfeeding are sensitive to new generation broadly neutralizing antibodies directed against quaternary and CD4-binding site epitopes. 
  • Signaling activities of the Drosophila wingless gene are separately mutable and appear to be transduced at the cell surface. 
  • Simultaneous genotyping and species identification using hybridization pattern recognition analysis of generic Mycobacterium DNA arrays. 
  • Slow algae, fast fungi: exceptionally high nucleotide substitution rate differences between lichenized fungi Omphalina and their symbiotic green algae Coccomyxa. 
  • SoDA: implementation of a 3D alignment algorithm for inference of antigen receptor recombinations. 
  • Social networks predict gut microbiome composition in wild baboons. 
  • SpA: web-accessible spectratype analysis: data management, statistical analysis and visualization. 
  • Species discovery and validation in a cryptic radiation of endangered primates: coalescent-based species delimitation in Madagascar's mouse lemurs. 
  • Specific polymorphisms in hepatitis C virus genotype 3 core protein associated with intracellular lipid accumulation. 
  • Spliceosome-mediated RNA trans-splicing as a tool for gene therapy. 
  • Stabilization of microsatellite sequences by variant repeats in the yeast Saccharomyces cerevisiae. 
  • Statistical inference of sequence-dependent mutation rates. 
  • Strain-Specific V3 and CD4 Binding Site Autologous HIV-1 Neutralizing Antibodies Select Neutralization-Resistant Viruses. 
  • Stratified whole genome linkage analysis of Chiari type I malformation implicates known Klippel-Feil syndrome genes as putative disease candidates. 
  • Structure, function, and phylogeny of the mating locus in the Rhizopus oryzae complex. 
  • Structure-guided reprogramming of serine recombinase DNA sequence specificity. 
  • Study of a US cohort supports the role of ZNF644 and high-grade myopia susceptibility. 
  • Sturge-Weber syndrome and port-wine stains caused by somatic mutation in GNAQ. 
  • Superoxide dismutase influences the virulence of Cryptococcus neoformans by affecting growth within macrophages. 
  • Surface-enhanced Raman gene probes. 
  • Survey of variation in human transcription factors reveals prevalent DNA binding changes. 
  • Synchronous luminescence: a new detection technique for multiple fluorescent probes used for DNA sequencing. 
  • TM4SF20 ancestral deletion and susceptibility to a pediatric disorder of early language delay and cerebral white matter hyperintensities. 
  • TMEM237 is mutated in individuals with a Joubert syndrome related disorder and expands the role of the TMEM family at the ciliary transition zone. 
  • TNXB mutations can cause vesicoureteral reflux. 
  • Targeted resequencing identifies PTCH1 as a major contributor to ocular developmental anomalies and extends the SOX2 regulatory network. 
  • Targeted sequencing in chromosome 17q linkage region identifies familial glioma candidates in the Gliogene Consortium. 
  • Telaprevir for previously untreated chronic hepatitis C virus infection. 
  • Temporal Stability of Molecular Diversity Measures in Natural Populations of Drosophila pseudoobscura and Drosophila persimilis. 
  • Testing Rare-Variant Association without Calling Genotypes Allows for Systematic Differences in Sequencing between Cases and Controls. 
  • Testing the effect of rare compound-heterozygous and recessive mutations in case--parent sequencing studies. 
  • Testing the hypothesis of a recombinant origin of human immunodeficiency virus type 1 subtype E. 
  • The 1.4-Mb CMT1A duplication/HNPP deletion genomic region reveals unique genome architectural features and provides insights into the recent evolution of new genes. 
  • The A581G Mutation in the Gene Encoding Plasmodium falciparum Dihydropteroate Synthetase Reduces the Effectiveness of Sulfadoxine-Pyrimethamine Preventive Therapy in Malawian Pregnant Women. 
  • The AZFc region of the Y chromosome features massive palindromes and uniform recurrent deletions in infertile men. 
  • The Arabidopsis NPR1 gene that controls systemic acquired resistance encodes a novel protein containing ankyrin repeats. 
  • The Cryptococcus neoformans genome sequencing project. 
  • The DNA sequence and biological annotation of human chromosome 1. 
  • The DNA sequence of the human X chromosome. 
  • The Danish 1905 cohort: a genetic-epidemiological nationwide survey. 
  • The GroES antigens of Mycobacterium avium and Mycobacterium paratuberculosis. 
  • The LabFlow system for workflow management in large scale biology research laboratories. 
  • The MedSeq Project: a randomized trial of integrating whole genome sequencing into clinical medicine. 
  • The RAM1 gene encoding a protein-farnesyltransferase beta-subunit homologue is essential in Cryptococcus neoformans. 
  • The Undiagnosed Diseases Network: Accelerating Discovery about Health and Disease. 
  • The adaptive radiation of lichen-forming Teloschistaceae is associated with sunscreening pigments and a bark-to-rock substrate shift. 
  • The calmodulin-dependent protein phosphatase catalytic subunit (calcineurin A) is an essential gene in Aspergillus nidulans. 
  • The calmodulin-dependent protein phosphatase catalytic subunit (calcineurin A) is an essential gene in Aspergillus nidulans. 
  • The characterization of twenty sequenced human genomes. 
  • The cyanide-resistant alternative oxidases from the fungi Pichia stipitis and Neurospora crassa are monomeric and lack regulatory features of the plant enzyme. 
  • The dangers of diagnostic monopolies. 
  • The differential expression of wound-inducible lipoxygenase genes in soybean leaves. 
  • The distribution of feline immunodeficiency virus in tissue compartments of feral domestic cats. 
  • The distribution of variation in regulatory gene segments, as present in MHC class II promoters. 
  • The draft genome of the transgenic tropical fruit tree papaya (Carica papaya Linnaeus). 
  • The effects of Cenozoic global change on squirrel phylogeny. 
  • The evolutionary forest algorithm. 
  • The evolutionary history of ferns inferred from 25 low-copy nuclear genes. 
  • The extent and genetic basis of phenotypic divergence in life history traits in Mimulus guttatus. 
  • The founding of Mauritian endemic coffee trees by a synchronous long-distance dispersal event. 
  • The genetic landscape of mutations in Burkitt lymphoma. 
  • The genetic landscape of the childhood cancer medulloblastoma. 
  • The genome of the basidiomycetous yeast and human pathogen Cryptococcus neoformans. 
  • The genome of the sea urchin Strongylocentrotus purpuratus. 
  • The genomic landscape of mantle cell lymphoma is related to the epigenetically determined chromatin state of normal B cells. 
  • The lemur revolution starts now: the genomic coming of age for a non-model organism. 
  • The mammalian Rad24 homologous to yeast Saccharomyces cerevisiae Rad24 and Schizosaccharomyces pombe Rad17 is involved in DNA damage checkpoint. 
  • The near-naked hairless (Hr(N)) mutation disrupts hair formation but is not due to a mutation in the Hairless coding region. 
  • The predictive capacity of personal genome sequencing. 
  • The prevalence and regulation of antisense transcripts in Schizosaccharomyces pombe. 
  • The reference genome sequence of Saccharomyces cerevisiae: then and now. 
  • The smallest membrane anchoring subunit (QPs3) of bovine heart mitochondrial succinate-ubiquinone reductase. Cloning, sequencing, topology, and Q-binding domain. 
  • The spatial scale of genetic subdivision in populations of Ifremeria nautilei, a hydrothermal-vent gastropod from the southwest Pacific. 
  • The trehalose synthesis pathway is an integral part of the virulence composite for Cryptococcus gattii. 
  • The utility of PacBio circular consensus sequencing for characterizing complex gene families in non-model organisms. 
  • The utility of the traditional medical genetics diagnostic evaluation in the context of next-generation sequencing for undiagnosed genetic disorders. 
  • The yeast carboxyl-terminal repeat domain kinase CTDK-I is a divergent cyclin-cyclin-dependent kinase complex. 
  • Theoretical and practical advances in genome halving. 
  • Three crocodilian genomes reveal ancestral patterns of evolution among archosaurs. 
  • Thymus transplantation restores the repertoires of forkhead box protein 3 (FoxP3)+ and FoxP3- T cells in complete DiGeorge anomaly. 
  • Tigecycline therapy for carbapenem-resistant Klebsiella pneumoniae (CRKP) bacteriuria leads to tigecycline resistance. 
  • Toward a Wolbachia multilocus sequence typing system: discrimination of Wolbachia strains present in Drosophila species. 
  • Transcriptome analysis of mouse stem cells and early embryos. 
  • Transcriptome-mining for single-copy nuclear markers in ferns. 
  • Transient compartmentalization of simian immunodeficiency virus variants in the breast milk of african green monkeys. 
  • Transmission of single HIV-1 genomes and dynamics of early immune escape revealed by ultra-deep sequencing. 
  • Trilateral retinoblastoma in a patient with Peutz-Jeghers syndrome. 
  • Ultra-rare genetic variation in common epilepsies: a case-control sequencing study. 
  • Uncovering the roles of rare variants in common disease through whole-genome sequencing. 
  • Unique expression of a sporophytic character on the gametophytes of notholaenid ferns (Pteridaceae). 
  • Using ERDS to infer copy-number variants in high-coverage genomes. 
  • Using PEBBLE for the evolutionary analysis of serially sampled molecular sequences. 
  • Using a multigene phylogenetic analysis to assess generic delineation and character evolution in Verrucariaceae (Verrucariales, Ascomycota). 
  • Variable but persistent coexistence of Prochlorococcus ecotypes along temperature gradients in the ocean's surface mixed layer. 
  • Variant ASGR1 Associated with a Reduced Risk of Coronary Artery Disease. 
  • Variants in melanocortin 1 receptor gene contribute to risk of melanoma--a direct sequencing analysis in a Texas population. 
  • Vibrio metoecus sp. nov., a close relative of Vibrio cholerae isolated from coastal brackish ponds and clinical specimens. 
  • Vironome of Kaposi sarcoma associated herpesvirus-inflammatory cytokine syndrome in an AIDS patient reveals co-infection of human herpesvirus 8 and human herpesvirus 6A. 
  • Virulence determinants in the obligate intracellular pathogen Chlamydia trachomatis revealed by forward genetic approaches. 
  • WASABI: an automated sequence processing system for multigene phylogenies. 
  • West Nile virus in Mexico: evidence of widespread circulation since July 2002. 
  • Whole genome re-sequencing to identify suppressor mutations of mutant and foreign Escherichia coli FtsZ. 
  • Whole genome sequencing identifies circulating Beijing-lineage Mycobacterium tuberculosis strains in Guatemala and an associated urban outbreak. 
  • Whole genome sequencing in patients with retinitis pigmentosa reveals pathogenic DNA structural changes and NEK2 as a new disease gene. 
  • Whole-exome sequencing implicates UBE3D in age-related macular degeneration in East Asian populations. 
  • Whole-genome analyses resolve early branches in the tree of life of modern birds. 
  • Whole-genome sequencing of a single proband together with linkage analysis identifies a Mendelian disease gene. 
  • Wide variation in the multiplicity of HIV-1 infection among injection drug users. 
  • Yantar, a conserved arginine-rich protein is involved in Drosophila hemocyte development. 
  • Yeast diversity sampling on the San Juan Islands reveals no evidence for the spread of the Vancouver Island Cryptococcus gattii outbreak to this locale. 
  • Young Investigator Challenge: Molecular testing in noninvasive follicular thyroid neoplasm with papillary-like nuclear features. 
  • [PCR amplification and structural analysis of two paralogous rat estrogen sulfotransferase genes] 
  • alphaSU2, an epithelial integrin that binds laminin in the sea urchin embryo. 
  • cDNA cloning and sequencing of Ca2+/calmodulin-dependent protein kinase IIalpha subunit and its mRNA expression in diisopropyl phosphorofluoridate (DFP)-treated hen central nervous system. 
  • cnvCapSeq: detecting copy number variation in long-range targeted resequencing data. 
• 

  Keywords of People

  • Alberts, Susan C., Robert F. Durden Professor of Biology, Marine Science and Conservation
  • Bejsovec, Amy, Associate Professor of Biology, Biology
  • Berchuck, Andrew, James M. Ingram Professor of Gynecologic Oncology, Obstetrics and Gynecology, Gynecologic Oncology
  • Buckley, Rebecca Hatcher, James Buren Sidbury Professor of Pediatrics, in the School of Medicine, Immunology
  • Cunningham, Coleen Kathryn, Professor of Pediatrics, Pathology
  • Davis, Erica Ellen, Associate Professor of Pediatrics, Cell Biology
  • Erickson, Harold Paul, James B. Duke Professor of Medicine, Cell Biology
  • Gordan, Raluca Mihaela, Assistant Professor in Biostatistics & Bioinformatics, Computer Science
  • Gunn, Michael Dee, Professor of Medicine, Immunology
  • Hartemink, Alexander J., Professor in the Department of Computer Science, Computer Science
  • Hogan, Brigid L. M., George Barth Geller Professor, Cell Biology
  • Li, Yi-Ju, Associate Professor of Biostatistics and Bioinformatics, Biostatistics & Bioinformatics
  • Liu, Yutao, Adjunct Assistant Professor in the Department of Medicine, Medicine, Medical Genetics
  • McLendon, Roger Edwin, Professor of Pathology, Pathology
  • Mitchell-Olds, Thomas, Newman Ivey White Professor of Biology in Trinity College of Arts and Sciences, Biology
  • Noor, Mohamed A. F., Professor of Biology, Biology
  • Premont, Richard Thomas, Associate Professor in Medicine, Medicine, Gastroenterology
  • Roth, V. Louise, Professor in the Department of Biology, Evolutionary Anthropology
  • Shinohara, Mari L., Associate Professor of Immunology, Immunology
  • Wray, Gregory Allan, Professor of Biology, Evolutionary Anthropology
  • Yan, Hai, Henry S. Friedman Professor of Neuro-Oncology in the School of Medicine, Pathology
  • Yoder, Anne Daphne, Braxton Craven Professor of Evolutionary Biology, Duke Science & Society