Receptors, Opioid, mu
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Subject Areas on Research
- A genetic association study of the mu opioid receptor and severe opioid dependence.
- A novel alternatively spliced isoform of the mu-opioid receptor: functional antagonism.
- An in vitro autoradiographic analysis of mu and delta opioid binding in the hippocampal formation of kindled rats.
- Ascaris suum, an intestinal parasite, produces morphine.
- Autoradiographic localization of benzomorphan binding sites in rat brain.
- Autoradiographic quantification of neurochemical markers of serotonin, dopamine and opioid systems in rat brain mesolimbic regions following chronic St John's wort treatment.
- Central effect of mu-opioid agonists on antral motility in conscious rats.
- Changes in mu opioid receptors and rheological properties of erythrocytes among opioid abusers.
- Child μ-opioid receptor gene variant influences parent-child relations.
- Depression of LTP in rat dentate gyrus by naloxone is reversed by GABAA blockade.
- Desensitization of G protein-coupled receptors and neuronal functions.
- Differential Regulation of 6- and 7-Transmembrane Helix Variants of μ-Opioid Receptor in Response to Morphine Stimulation.
- Differential mechanisms of morphine antinociceptive tolerance revealed in (beta)arrestin-2 knock-out mice.
- Early ontogeny of kappa-opioid receptor regulation of prolactin secretion in the rat.
- Effects of specific mu and kappa opiate tolerance and abstinence on hypothalamo-pituitary-adrenal axis secretion in the rat.
- Elevated mu-opioid receptor expression in the nucleus of the solitary tract accompanies attenuated withdrawal signs after chronic low dose naltrexone in opiate-dependent rats.
- Enhanced morphine analgesia in mice lacking beta-arrestin 2.
- Ethanol consumption by Fawn-Hooded rats following abstinence: effect of naltrexone and changes in mu-opioid receptor density.
- Expression of mu-, delta-, and kappa-opioid receptor-like immunoreactivities in rat dorsal root ganglia after carrageenan-induced inflammation.
- Gaps in the evidence base of opioids for refractory breathlessness. A future work plan?
- Glafenine-induced intestinal injury in zebrafish is ameliorated by μ-opioid signaling via enhancement of Atf6-dependent cellular stress responses.
- Heterogeneity in presynaptic regulation of GABA release from hippocampal inhibitory neurons.
- Importance of voltage-dependent inactivation in N-type calcium channel regulation by G-proteins.
- Increased sensitivity to mu opiate antinociception in the neonatal rat despite weaker receptor-guanyl nucleotide binding protein coupling.
- Involvement of cAMP-dependent protein kinase in mu-opioid modulation of NMDA-mediated synaptic currents.
- Melanocortin-1 receptor gene variants affect pain and mu-opioid analgesia in mice and humans.
- Molecular assays for characterization of alternatively spliced isoforms of the u opioid receptor (MOR).
- Morphine side effects in beta-arrestin 2 knockout mice.
- Morphine-induced physiological and behavioral responses in mice lacking G protein-coupled receptor kinase 6.
- Mu Opioid Splice Variant MOR-1K Contributes to the Development of Opioid-Induced Hyperalgesia.
- Mu opioid receptor-mediated modulation of synaptic currents in dentate granule cells of rat hippocampus.
- Mu- and kappa-opiate receptor control of prolactin secretion in rats: ontogeny and interaction with serotonin.
- Mu-opioid receptor desensitization by beta-arrestin-2 determines morphine tolerance but not dependence.
- Mu-opioid receptors selectively regulate basal inhibitory transmission in the central amygdala: lack of ethanol interactions.
- Multiple endocytic pathways of G protein-coupled receptors delineated by GIT1 sensitivity.
- Neuronal nitric oxide modulates morphine antinociceptive tolerance by enhancing constitutive activity of the mu-opioid receptor.
- Nitric oxide production is enhanced in rat brain before oxygen-induced convulsions.
- Novel exonic mu-opioid receptor gene (OPRM1) polymorphisms not associated with opioid dependence.
- Ontogeny of mu- and kappa-opiate receptor control of the hypothalamo-pituitary-adrenal axis in rats.
- Opiates transdeactivate chemokine receptors: delta and mu opiate receptor-mediated heterologous desensitization.
- Opioid inhibition of rapid eye movement sleep by a specific mu receptor agonist.
- Opioid-independent mechanisms supporting offset analgesia and temporal sharpening of nociceptive information.
- Opioid-mediated facilitation of long-term potentiation at the lateral perforant path-dentate granule cell synapse.
- Peripheral axonal injury results in reduced mu opioid receptor pre- and post-synaptic action in the spinal cord.
- Pharmacogenomics for personalized pain medicine.
- Potentiated opioid analgesia in norepinephrine transporter knock-out mice.
- Quantitative autoradiographic analysis of mu and delta opioid binding sites in the rat hippocampal formation.
- Relative opioid efficacy is determined by the complements of the G protein-coupled receptor desensitization machinery.
- Role for G protein-coupled receptor kinase in agonist-specific regulation of mu-opioid receptor responsiveness.
- Role of mu-opioid and NMDA receptors in the development and maintenance of repeated swim stress-induced thermal hyperalgesia.
- Sortase ligation enables homogeneous GPCR phosphorylation to reveal diversity in β-arrestin coupling.
- Structural and functional interactions between six-transmembrane μ-opioid receptors and β2-adrenoreceptors modulate opioid signaling.
- Suppression of alcohol intake by chronic naloxone treatment in P rats: tolerance development and elevation of opiate receptor binding.
- Synthesis and biological activity of a novel methylamine-bridged enkephalin analogue (MABE): a new route to cyclic peptides and peptidomimetics.
- The effect of fentanyl on c-fos expression in the trigeminal brainstem complex produced by pulpal heat stimulation in the ferret.
- The novel micro-opioid receptor antagonist, [N-allyl-Dmt(1)]endomorphin-2, attenuates the enhancement of GABAergic neurotransmission by ethanol.
- The ontogeny of mu opiate tolerance and dependence in the rat: antinociceptive and biochemical studies.
- Transformation of mu-opioid receptor agonists into biologically potent mu-opioid receptor antagonists.
- beta-Endorphin-containing memory-cells and mu-opioid receptors undergo transport to peripheral inflamed tissue.
- mu-Opioid agonists stimulate growth hormone secretion in immature rats.
- β-arrestin-2 regulates NMDA receptor function in spinal lamina II neurons and duration of persistent pain.
- μ-Opioid Receptor Gene A118 G Variants and Persistent Pain Symptoms Among Men and Women Experiencing Motor Vehicle Collision.
- μ-Opioid receptor 6-transmembrane isoform: A potential therapeutic target for new effective opioids.
- μ-Opioid receptor gene A118G polymorphism predicts survival in patients with breast cancer.