Receptors, Opioid, kappa
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Subject Areas on Research
- A randomized proof-of-mechanism trial applying the 'fast-fail' approach to evaluating κ-opioid antagonism as a treatment for anhedonia.
- Activation of kappa opioid receptors by U50488H and morphine enhances the release of substance P from rat trigeminal nucleus slices.
- Antidepressant-like effects of kappa-opioid receptor antagonists in the forced swim test in rats.
- Autoradiographic localization of benzomorphan binding sites in rat brain.
- Buprenorphine metabolites, buprenorphine-3-glucuronide and norbuprenorphine-3-glucuronide, are biologically active.
- Clinical trial: asimadoline in the treatment of patients with irritable bowel syndrome.
- Early ontogeny of kappa-opioid receptor regulation of prolactin secretion in the rat.
- Effects of specific mu and kappa opiate tolerance and abstinence on hypothalamo-pituitary-adrenal axis secretion in the rat.
- Expression of mu-, delta-, and kappa-opioid receptor-like immunoreactivities in rat dorsal root ganglia after carrageenan-induced inflammation.
- Induction of bladder sphincter dyssynergia by kappa-2 opioid receptor agonists in the female rat.
- Interaction of CRF and kappa opioid systems on GABAergic neurotransmission in the mouse central amygdala.
- Kappa-Opioid Antagonists for Psychiatric Disorders: From Bench to Clinical Trials.
- Mu- and kappa-opiate receptor control of prolactin secretion in rats: ontogeny and interaction with serotonin.
- Neuropathic pain activates the endogenous kappa opioid system in mouse spinal cord and induces opioid receptor tolerance.
- Ontogeny of mu- and kappa-opiate receptor control of the hypothalamo-pituitary-adrenal axis in rats.
- Prolonged kappa opioid receptor phosphorylation mediated by G-protein receptor kinase underlies sustained analgesic tolerance.
- Regulation and function of MeCP2 Ser421 phosphorylation in U50488-induced conditioned place aversion in mice.
- Structure-based design, synthesis, and biochemical and pharmacological characterization of novel salvinorin A analogues as active state probes of the kappa-opioid receptor.
- Synthesis and biological activity of a novel methylamine-bridged enkephalin analogue (MABE): a new route to cyclic peptides and peptidomimetics.
- The association of NHERF adaptor proteins with g protein-coupled receptors and receptor tyrosine kinases.
- The multifunctional peptide DN-9 produced peripherally acting antinociception in inflammatory and neuropathic pain via μ- and κ-opioid receptors.
- p38: the link between the kappa-opioid receptor and dysphoria.
- κ-Opioid receptors in the central amygdala regulate ethanol actions at presynaptic GABAergic sites.