-
Subject Areas on Research
-
A cell-intrinsic role for CaMKK2 in granulocyte lineage commitment and differentiation.
-
Advances in the understanding and treatment of human severe combined immunodeficiency.
-
Amplification of suppressor inducer pathway with monoclonal antibody, anti-2H4, identifying a novel epitope of the common leukocyte antigen/T200 antigen.
-
An analysis of alternatively spliced CD45 mRNA transcripts during T cell maturation in humans.
-
Antibodies to CD45 and other cell membrane antigens in systemic lupus erythematosus.
-
CD11c(+)B220(+)Gr-1(+) cells in mouse lymph nodes and spleen display characteristics of plasmacytoid dendritic cells.
-
CD4+ memory T cells are the predominant population of HIV-1-infected lymphocytes in neonates and children.
-
CD45 mAb induces cell adhesion in peripheral blood mononuclear cells via lymphocyte function-associated antigen-1 (LFA-1) and intercellular cell adhesion molecule 1 (ICAM-1).
-
CD45-deficient severe combined immunodeficiency caused by uniparental disomy.
-
CD8, FoxP3, and CD45RO+ Lymphocytic Infiltrates in Type I and Type II Endometrial Cancers in African American and European American Females.
-
CD95 (Fas)-dependent elimination of self-reactive B cells upon interaction with CD4+ T cells.
-
Characterization of circulating T cells specific for tumor-associated antigens in melanoma patients.
-
Circulating tumor cells in melanoma patients.
-
Combination antiretroviral therapy results in a rapid increase in T cell receptor variable region beta repertoire diversity within CD45RA CD8 T cells in human immunodeficiency virus-infected children.
-
Comparisons of CD8+ T cells specific for human immunodeficiency virus, hepatitis C virus, and cytomegalovirus reveal differences in frequency, immunodominance, phenotype, and interleukin-2 responsiveness.
-
Con A-induced suppressor cell function depends on the activation of the CD4+CD45RA inducer T cell subpopulation.
-
Decreased suppressor-inducer T lymphocytes in multiple sclerosis and other neurological diseases.
-
Dendritic epidermal T cells regulate skin antimicrobial barrier function.
-
Depletion of passenger leukocytes from corneal grafts: an effective means of promoting transplant survival?
-
Determination of proliferation index with MIB-1 in advanced ovarian cancer using quantitative image analysis.
-
Development and validation of a rapid, aldehyde dehydrogenase bright-based cord blood potency assay.
-
Development and validation of circulating tumour cell enumeration (Epic Sciences) as a prognostic biomarker in men with metastatic castration-resistant prostate cancer.
-
Differential CMV-specific CD8+ effector T cell responses in the lung allograft predominate over the blood during human primary infection.
-
Differential effects of vascular endothelial growth factor receptor-2 inhibitor ZD6474 on circulating endothelial progenitors and mature circulating endothelial cells: implications for use as a surrogate marker of antiangiogenic activity.
-
Effects of human immunodeficiency virus type 1 infection on CCR5 and CXCR4 coreceptor expression on CD4 T lymphocyte subsets in infants and adolescents.
-
Effects of human immunodeficiency virus type 1 on CD4 lymphocyte subset activation.
-
Epitope-specific signaling through CD45 on T lymphocytes leads to cAMP synthesis in monocytes after ICAM-1-dependent cellular interaction.
-
Ex vivo expansion, maturation, and activation of umbilical cord blood-derived T lymphocytes with IL-2, IL-12, anti-CD3, and IL-7. Potential for adoptive cellular immunotherapy post-umbilical cord blood transplantation.
-
Extranodal lymphoid microstructures in inflamed muscle and disease severity of new-onset juvenile dermatomyositis.
-
Fibroblast activation protein expression by stromal cells and tumor-associated macrophages in human breast cancer.
-
Fine-needle aspiration findings in idiopathic retroperitoneal fibrosis.
-
Functional heterogeneity of vaccine-induced CD8(+) T cells.
-
Generation of Dhx9-deficient clones in T-cell development with a mitotic recombination technique.
-
Immunoreconstitution after ritonavir therapy in children with human immunodeficiency virus infection involves multiple lymphocyte lineages.
-
Increased loss of CCR5+ CD45RA- CD4+ T cells in CD8+ lymphocyte-depleted Simian immunodeficiency virus-infected rhesus monkeys.
-
Inflammatory cell distribution within and along asthmatic airways.
-
Late-stage tumors induce anemia and immunosuppressive extramedullary erythroid progenitor cells.
-
Linkage of the CCR5 Delta 32 mutation with a functional polymorphism of CD45RA.
-
Long-term repopulating ability of xenogeneic transplanted human fetal liver hematopoietic stem cells in sheep.
-
Long-term virologic and immunologic responses in human immunodeficiency virus type 1-infected children treated with indinavir, zidovudine, and lamivudine.
-
Microvascular inflammation in renal allograft biopsies assessed by endothelial and leukocyte co-immunostain: a retrospective study on reproducibility and clinical/prognostic correlates.
-
Modulation of CD45 tyrosine phosphatase activity by antigen.
-
Nonmyeloablative regimen preserves "niches" allowing for peripheral expansion of donor T-cells.
-
PTPRC (CD45) is not associated with the development of multiple sclerosis in U.S. patients.
-
Phenotypic and functional characterization of cytotoxic T lymphocytes by flow cytometry.
-
Plexin-B2 negatively regulates macrophage motility, Rac, and Cdc42 activation.
-
Profiling of CD4+, CD8+, and CD4+CD25+CD45RO+FoxP3+ T cells in patients with malignant glioma reveals differential expression of the immunologic transcriptome compared with T cells from healthy volunteers.
-
Purkinje cell loss in experimental autoimmune encephalomyelitis.
-
Regulation of the tyrosine kinase-dependent adhesion pathway in human lymphocytes through CD45.
-
Renal TGF-beta in HIV-associated kidney diseases.
-
Role of vascular leukocytes in ovarian cancer neovascularization.
-
Status of activation of circulating vaccine-elicited CD8+ T cells.
-
T cell repertoire development in humans with SCID after nonablative allogeneic marrow transplantation.
-
T-Cell receptor Vbeta repertoire CDR3 length diversity differs within CD45RA and CD45RO T-cell subsets in healthy and human immunodeficiency virus-infected children.
-
The cell and molecular basis of leukocyte common antigen (CD45)-triggered, lymphocyte function-associated antigen-1-/intercellular adhesion molecule-1-dependent, leukocyte adhesion.
-
The effects of smoking on levels of endothelial progenitor cells and microparticles in the blood of healthy volunteers.
-
The exon A (C77G) mutation is a common cause of abnormal CD45 splicing in humans.
-
The human thymic microenvironment during organ culture.
-
The inhibitory coreceptor CD22 restores B cell signaling by developmentally regulating Cd45-/- immunodeficient B cells.
-
The multiple causes of human SCID.
-
The role of CD45RO in antithymocyte globulin's stimulation of primitive haemopoietic cells.
-
The role of functionally distinct helper T lymphocyte subpopulations in the induction of human B cell differentiation.
-
The transcription factor c-Maf is essential for the commitment of IL-17-producing γδ T cells.
-
Thymic function after hematopoietic stem-cell transplantation for the treatment of severe combined immunodeficiency.
-
Thymoma-associated immunodeficiency: a syndrome characterized by severe alterations in NK, T and B-cells and progressive increase in naïve CD8+ T Cells.
-
Unusual clinical and immunologic manifestations of transplacentally acquired maternal T cells in severe combined immunodeficiency.
-
Use of Hes1-GFP reporter mice to assess activity of the Hes1 promoter in bone cells under chronic inflammation.
-
Vascular leukocytes contribute to tumor vascularization.
-
Virulence factors identified by Cryptococcus neoformans mutant screen differentially modulate lung immune responses and brain dissemination.
-
[Effect of Shen warming Pi strengthening method on the expression of serum T cell subsets in IBS-D rats].
-
rHuKGF ameliorates symptoms in DSS and CD4(+)CD45RB(Hi) T cell transfer mouse models of inflammatory bowel disease.
-
Keywords of People
-
Berchuck, Andrew,
James M. Ingram Distinguished Professor of Gynecologic Oncology,
Obstetrics and Gynecology, Gynecologic Oncology
-
Buckley, Rebecca Hatcher,
Professor Emeritus of Pediatrics,
Pediatrics, Allergy and Immunology
-
Gunn, Michael Dee,
Professor of Medicine,
Immunology
-
Zhong, Xiaoping,
Professor of Pediatrics,
Immunology