Subject Areas on Research
- Cellular immunity to viral antigens limits E1-deleted adenoviruses for gene therapy.
- Dissecting the roles of E1A and E1B in adenoviral replication and RCAd-enhanced RDAd transduction efficacy on tumor cells.
- Inactivation of E2a in recombinant adenoviruses improves the prospect for gene therapy in cystic fibrosis.
- Intra-arterial administration of a replication-selective adenovirus (dl1520) in patients with colorectal carcinoma metastatic to the liver: a phase I trial.