Karnofsky Performance Status

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  Subject Areas on Research

  • A comparison of performance-based measures of function in HIV-associated neurocognitive disorders. 
  • A new prognostic index and comparison to three other indices for patients with brain metastases: an analysis of 1,960 patients in the RTOG database. 
  • A nomogram for individualized estimation of survival among patients with brain metastasis. 
  • A phase 2 trial of azacitidine and gemtuzumab ozogamicin therapy in older patients with acute myeloid leukemia. 
  • A phase I study of dose-dense topotecan given upfront to standard therapy in patients with small cell lung cancer. 
  • A phase III randomized prospective trial of external beam radiotherapy, mitomycin C, carmustine, and 6-mercaptopurine for the treatment of adults with anaplastic glioma of the brain. CNS Cancer Consortium. 
  • Aging and cancer. 
  • Assessment of physical functioning in recurrent glioma: preliminary comparison of performance status to functional capacity testing. 
  • Association of surgically acquired motor and language deficits on overall survival after resection of glioblastoma multiforme. 
  • Clinical characteristics and treatment of malignant brainstem gliomas in elderly patients. 
  • Coronary artery bypass grafting in patients with dialysis-dependent renal failure. 
  • Correlation between the international consensus definition of the Cancer Anorexia-Cachexia Syndrome (CACS) and patient-centered outcomes in advanced non-small cell lung cancer. 
  • Cytokines in pancreatic carcinoma: correlation with phenotypic characteristics and prognosis. 
  • Defining the optimal planning target volume in image-guided stereotactic radiosurgery of brain metastases: results of a randomized trial. 
  • Developing a cancer-specific geriatric assessment: a feasibility study. 
  • Development of a disease-specific graded prognostic assessment index for the management of sarcoma patients with brain metastases (Sarcoma-GPA). 
  • Diagnosis-specific prognostic factors, indexes, and treatment outcomes for patients with newly diagnosed brain metastases: a multi-institutional analysis of 4,259 patients. 
  • Effect of Targeted Therapies on Prognostic Factors, Patterns of Care, and Survival in Patients With Renal Cell Carcinoma and Brain Metastases. 
  • Effect of imaging and catheter characteristics on clinical outcome for patients in the PRECISE study. 
  • Effect of postoperative complications on health and employment following liver transplantation. 
  • Effect of tumor subtype on survival and the graded prognostic assessment for patients with breast cancer and brain metastases. 
  • Estimating Survival in Melanoma Patients With Brain Metastases: An Update of the Graded Prognostic Assessment for Melanoma Using Molecular Markers (Melanoma-molGPA). 
  • Estimating survival for renal cell carcinoma patients with brain metastases: an update of the Renal Graded Prognostic Assessment tool. 
  • Exercise behavior, functional capacity, and survival in adults with malignant recurrent glioma. 
  • Extent of surgical resection is independently associated with survival in patients with hemispheric infiltrating low-grade gliomas. 
  • Functional status after lung transplantation in older adults in the post-allocation score era. 
  • Glioblastoma in the elderly: the effect of aggressive and modern therapies on survival. 
  • Health-related quality of life in men receiving prostate brachytherapy on RTOG 98-05. 
  • Implementing a geriatric assessment in cooperative group clinical cancer trials: CALGB 360401. 
  • Independent association of extent of resection with survival in patients with malignant brain astrocytoma. 
  • Influence of comorbidity on racial differences in receipt of surgery among US veterans with early-stage non-small-cell lung cancer. 
  • Inpatient care for elderly cancer patients: the role for Geriatric Evaluation and Management Units in fulfilling goals for care. 
  • International practice survey on palliative lung radiotherapy: third international consensus workshop on palliative radiotherapy and symptom control. 
  • Laser Ablation of Abnormal Neurological Tissue Using Robotic NeuroBlate System (LAANTERN): 12-Month Outcomes and Quality of Life After Brain Tumor Ablation. 
  • Methotrexate and cyclosporine for graft-vs.-host disease prevention: what length of therapy with cyclosporine? 
  • Molecular pathologic substaging in 244 stage I non-small-cell lung cancer patients: clinical implications. 
  • Patient factors associated with quality of life in atrial fibrillation. 
  • Phase 1 study of N(1),N(11)‑diethylnorspermine (DENSPM) in patients with advanced hepatocellular carcinoma. 
  • Phase I study of pazopanib plus TH-302 in advanced solid tumors. 
  • Phase I trial of menadiol diphosphate (vitamin K3) in advanced malignancy. 
  • Phase II study of metronomic chemotherapy with bevacizumab for recurrent glioblastoma after progression on bevacizumab therapy. 
  • Primary lesion location influences postoperative survival in patients with metastatic colorectal spinal lesions. 
  • Prospective study of neuropsychologic testing and quality-of-life assessment of adults with primary malignant brain tumors. 
  • Radiation therapy for rectosigmoid and rectal cancer: results of the 1992-1994 Patterns of Care process survey. 
  • Randomized trial in malignant biliary obstruction: plastic vs partially covered metal stents. 
  • Resection of gliomas deemed inoperable by neurosurgeons based on preoperative imaging studies. 
  • Sickness behavior clustering in children with cancer. 
  • Stereotactic radiosurgery in the management of brain metastases from primary thyroid cancers. 
  • Survival in Patients With Brain Metastases: Summary Report on the Updated Diagnosis-Specific Graded Prognostic Assessment and Definition of the Eligibility Quotient. 
  • Symptom clusters in children and adolescents receiving cisplatin, doxorubicin, or ifosfamide. 
  • Tailoring cognitive-behavioral treatment for cancer pain. 
  • Temozolomide-induced flare in high-grade gliomas: a new clinical entity. 
  • The safety and versatility of video-thoracoscopy: a prospective analysis of 895 consecutive cases. 
  • Utility of CT assessment in hematology patients with invasive aspergillosis: a post-hoc analysis of phase 3 data. 
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  Keywords of People

  • McConnell, Eleanor Schildwachter, Associate Professor in the School of Nursing, School of Nursing