Asbestos, Crocidolite
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Subject Areas on Research
- Autocrine growth stimulation by transforming growth factor alpha in asbestos-transformed rat mesothelial cells.
- Clearance and dimensional changes of crocidolite asbestos fibers isolated from lungs of rats following short-term exposure.
- Crocidolite and mesothelioma.
- DNA strand breaks following in vitro exposure to asbestos increase with surface-complexed [Fe3+].
- Fiber potency vs. importance.
- Generation of hydroxyl radical by crocidolite asbestos is proportional to surface [Fe3+].
- In vivo accumulation of iron on crocidolite is associated with decrements in oxidant generation by the fiber.
- Mineralogy of asbestos.
- Oxalate deposition on asbestos bodies.
- Oxidant generation promotes iron sequestration in BEAS-2B cells exposed to asbestos.
- Phagocyte-generated superoxide reduces Fe3+ to displace it from the surface of asbestos.
- Pleural macrophage recruitment and activation in asbestos-induced pleural injury.
- Pulmonary and pleural leukocytes from F344 rats produce elevated levels of fibronectin following inhalation of refractory ceramic fibers.
- Secreted extracellular domains of macrophage scavenger receptors form elongated trimers which specifically bind crocidolite asbestos.
- Soluble ICAM-1, MCP-1, and MIP-2 protein secretion by rat pleural mesothelial cells following exposure to amosite asbestos.