Deuterium Oxide

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  Subject Areas on Research

  • A mass spectrometry-based probe of equilibrium intermediates in protein-folding reactions. 
  • Accuracy and precision of a new H/D exchange- and mass spectrometry-based technique for measuring the thermodynamic properties of protein-peptide complexes. 
  • Dynamics of glutathione and ophthalmate traced with 2H-enriched body water in rats and humans. 
  • Effect of fasting and feeding on measurement of carbon dioxide production using doubly labeled water. 
  • Hydrogen bonding of beta-turn structure is stabilized in D(2)O. 
  • Mutational analysis of active site residues in the Staphylococcus aureus transpeptidase SrtA. 
  • Quantifying ceramide kinetics in vivo using stable isotope tracers and LC-MS/MS. 
  • Rapid measurement of total body water to facilitate clinical decision making in hospitalized elderly patients.