Cell Transplantation

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  Subject Areas on Research

  • Activation of pmar1 controls specification of micromeres in the sea urchin embryo. 
  • Aerosol transfer of bladder urothelial and smooth muscle cells onto demucosalized colonic segments for bladder augmentation: in vivo, long term, and functional pilot study. 
  • Biomechanical factors in tissue engineered meniscal repair. 
  • Bringing cardiovascular cell-based therapy to clinical application: perspectives based on a National Heart, Lung, and Blood Institute Cell Therapy Working Group meeting. 
  • Calmodulin-dependent protein kinase IV regulates hematopoietic stem cell maintenance. 
  • Cell cycle control in the terminally differentiated myocyte. A platform for myocardial repair? 
  • Combined PI3K/Akt and Smad2 Activation Promotes Corneal Endothelial Cell Proliferation. 
  • Comparison of benefits on myocardial performance of cellular cardiomyoplasty with skeletal myoblasts and fibroblasts. 
  • Cooperation of p53 loss of function and v-Ha-ras in transformation of mouse keratinocyte cell lines. 
  • Delivery of primary autologous skeletal myoblasts into rabbit heart by coronary infusion: a potential approach to myocardial repair. 
  • Derivation of chondrogenically-committed cells from human embryonic cells for cartilage tissue regeneration. 
  • Embryonic germ cell lines and their derivation from mouse primordial germ cells. 
  • Engineered cell lines for insulin replacement in diabetes: current status and future prospects. 
  • Engineered pluripotent mesenchymal cells integrate and differentiate in regenerating bone: a novel cell-mediated gene therapy. 
  • Enhancement of human hematopoiesis by mast cell growth factor in human-sheep chimeras created by the in utero transplantation of human fetal hematopoietic cells. 
  • Gastric graft-versus-host disease: a blinded histologic study. 
  • Gene dose-dependent control of hematopoiesis and hematologic tumor suppression by CBP. 
  • Gene therapy in a xenograft model of cystic fibrosis lung corrects chloride transport more effectively than the sodium defect. 
  • Gene therapy in transplantation. 
  • Gene therapy of cystic fibrosis lung disease using E1 deleted adenoviruses: a phase I trial. 
  • Generation of normal lymphocyte populations following transplantation of adenosine-deaminase-deficient fetal liver cells. 
  • Genetic engineering of vein grafts resistant to atherosclerosis. 
  • Genomic amplification and oncogenic properties of the KCNK9 potassium channel gene. 
  • Graft-induced restoration of function in hereditary cerebellar ataxia. 
  • Graft-versus-host disease prevention by rapamycin: cellular mechanisms. 
  • Guidelines for the development and validation of new potency assays for the evaluation of umbilical cord blood. 
  • Immune Tolerance for Autoimmune Disease and Cell Transplantation. 
  • Improved efficacy of stem cell labeling for magnetic resonance imaging studies by the use of cationic liposomes. 
  • Increased yield of endothelial cells from peripheral blood for cell therapies and tissue engineering. 
  • Inhibition of established pancreatic cancers following specific active immunotherapy with interleukin-2 gene-transduced tumor cells. 
  • Intracardiac transplantation of skeletal myoblasts yields two populations of striated cells in situ. 
  • Intragraft CD11b(+) IDO(+) cells mediate cardiac allograft tolerance by ECDI-fixed donor splenocyte infusions. 
  • Islet cell transplantation for the treatment of diabetes mellitus. 
  • Manufacture and characterization of poly(alpha-hydroxy ester) thin films as temporary substrates for retinal pigment epithelium cells. 
  • Methods for transplantation of sea urchin blastomeres. 
  • Neural retinal cell transplantation. 
  • Neurite outgrowth from progeny of epidermal growth factor-responsive hippocampal stem cells is significantly less robust than from fetal hippocampal cells following grafting onto organotypic hippocampal slice cultures: effect of brain-derived neurotrophic factor. 
  • Novel delivery method to reduce endothelial injury in descemet stripping automated endothelial keratoplasty. 
  • Nrf2-mediated protection against 6-hydroxydopamine. 
  • Persistence and survival of autologous muscle derived cells versus bovine collagen as potential treatment of stress urinary incontinence. 
  • Pharmacokinetic changes induced by vasomodulators in kidneys, livers, muscles, and implanted tumors in rats as measured by dynamic Gd-DTPA-enhanced MRI. 
  • Photo-crosslinkable microcapsules formed by polyelectrolyte copolymer and modified collagen for rat hepatocyte encapsulation. 
  • Plexin-B2 negatively regulates macrophage motility, Rac, and Cdc42 activation. 
  • Pluripotency of mesenchymal stem cells derived from adult marrow. 
  • Poly(ethylene glycol) hydrogels with cell cleavable groups for autonomous cell delivery. 
  • Polyvinyl Pyrrolidone: A Novel Cryoprotectant in Islet Cell Cryopreservation. 
  • Potency analysis of cellular therapies: the emerging role of molecular assays. 
  • Prolonged postlesion transplantation delay adversely influences survival of both homotopic and heterotopic fetal hippocampal cell grafts in Kainate-lesioned CA3 region of adult hippocampus. 
  • Recovery from and consequences of severe iatrogenic lymphopenia (induced to treat autoimmune diseases). 
  • Regenerating functional myocardium: improved performance after skeletal myoblast transplantation. 
  • Regulation of P311 expression by Met-hepatocyte growth factor/scatter factor and the ubiquitin/proteasome system. 
  • Significance of regional draining lymph nodes in the development of tumor immunity: implications for cancer immunotherapy. 
  • Survival of grafted fetal neural cells in kainic acid lesioned CA3 region of adult hippocampus depends upon cell specificity. 
  • Systemic production of human granulocyte colony-stimulating factor in nonhuman primates by transplantation of genetically modified myoblasts. 
  • Systolic contraction within aneurysmal rabbit myocardium following transplantation of autologous skeletal myoblasts. 
  • T cells or active Epstein-Barr virus infection in the development of lymphoproliferative disease in human B cell-injected severe combined immunodeficient mice. 
  • Targeted drug delivery to C6 glioma by transferrin-coupled liposomes. 
  • Thymic stromal-cell abnormalities and dysregulated T-cell development in IL-2-deficient mice. 
  • Transplantation of vascular endothelial cells mediates the hematopoietic recovery and survival of lethally irradiated mice. 
  • Twist is an essential regulator of the skeletogenic gene regulatory network in the sea urchin embryo. 
  • Unintended changes in cognition, mood, and behavior arising from cell-based interventions for neurological conditions: ethical challenges. 
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  Keywords of People

  • Chen, Jun, Associate Professor of Medicine, Duke Cancer Institute
  • Hogan, Brigid L. M., George Barth Geller Professor, Cell Biology
  • Lee, Walter T, Associate Professor of Surgery, Radiation Oncology