Molecular Epidemiology

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  Subject Areas on Research

  • A Multicountry Molecular Analysis of Salmonella enterica Serovar Typhi With Reduced Susceptibility to Ciprofloxacin in Sub-Saharan Africa. 
  • A call to action for concentrated HIV epidemics. 
  • A computational framework to assess genome-wide distribution of polymorphic human endogenous retrovirus-K In human populations. 
  • A diverse population of Cryptococcus gattii molecular type VGIII in southern Californian HIV/AIDS patients. 
  • A novel haplotype-sharing approach for genome-wide case-control association studies implicates the calpastatin gene in Parkinson's disease. 
  • Absence of putative artemisinin resistance mutations among Plasmodium falciparum in Sub-Saharan Africa: a molecular epidemiologic study. 
  • Adverse subpopulation regression for multivariate outcomes with high-dimensional predictors. 
  • An "almost exhaustive" search-based sequential permutation method for detecting epistasis in disease association studies. 
  • An action agenda for HIV and sex workers. 
  • An isolate of human immunodeficiency virus type 1 originally classified as subtype I represents a complex mosaic comprising three different group M subtypes (A, G, and I). 
  • Assessing the co-variability of DNA methylation across peripheral cells and tissues: Implications for the interpretation of findings in epigenetic epidemiology. 
  • Association of XRCC1 polymorphisms and risk of differentiated thyroid carcinoma: a case-control analysis. 
  • Associations of Nocturnal Blood Pressure With Cognition by Self-Identified Race in Middle-Aged and Older Adults: The GENOA (Genetic Epidemiology Network of Arteriopathy) Study. 
  • Changing Characteristics of Staphylococcus aureus Bacteremia: Results From a 21-Year, Prospective, Longitudinal Study. 
  • Characterization of the Transmitted Virus in an Ongoing HIV-1 Epidemic Driven by Injecting Drug Use. 
  • Characterization of the emerging HIV type 1 and HCV epidemics among injecting drug users in Dushanbe, Tajikistan. 
  • Clinical profile and strain relatedness of recurrent enterococcal bacteremia. 
  • Clonal amplification and maternal-infant transmission of nevirapine-resistant HIV-1 variants in breast milk following single-dose nevirapine prophylaxis. 
  • Collaborative Molecular Epidemiology Study of Metabolic Dysregulation, DNA Methylation, and Breast Cancer Risk Among Nigerian Women: MEND Study Objectives and Design. 
  • Comparison of seven techniques for typing international epidemic strains of Clostridium difficile: restriction endonuclease analysis, pulsed-field gel electrophoresis, PCR-ribotyping, multilocus sequence typing, multilocus variable-number tandem-repeat analysis, amplified fragment length polymorphism, and surface layer protein A gene sequence typing. 
  • Complex transmission dynamics of clonally related virulent Mycobacterium tuberculosis associated with barhopping by predominantly human immunodeficiency virus-positive gay men. 
  • Country Level Diversity of the HIV-1 Pandemic between 1990 and 2015. 
  • Cryopreserving whole blood for functional assays using viable lymphocytes in molecular epidemiology studies. 
  • Cryptococcus gattii: an emerging fungal pathogen infecting humans and animals. 
  • D-Dimer in African Americans: Whole Genome Sequence Analysis and Relationship to Cardiovascular Disease Risk in the Jackson Heart Study. 
  • Emergence and pathogenicity of highly virulent Cryptococcus gattii genotypes in the northwest United States. 
  • Enhanced use of phylogenetic data to inform public health approaches to HIV among men who have sex with men. 
  • Epidemiologic links between drug use and HIV epidemics: an international perspective. 
  • Epidemiological investigation of vaginal Saccharomyces cerevisiae isolates by a genotypic method. 
  • Epidemiology and Molecular Epidemiology. 
  • Evidence of two distinct subsubtypes within the HIV-1 subtype A radiation. 
  • First reported case of Cryptococcus gattii in the Southeastern USA: implications for travel-associated acquisition of an emerging pathogen. 
  • Full-length nucleotide sequence of ERMAP alleles encoding Scianna (SC) antigens. 
  • Functional polymorphisms in the promoter regions of the FAS and FAS ligand genes and risk of bladder cancer in south China: a case-control analysis. 
  • Genetic analysis for common complex disease. 
  • Genetic epidemiology of neural tube defects. 
  • Genetic factors contribute to bleeding after cardiac surgery. 
  • Genetic simulation tools for post-genome wide association studies of complex diseases. 
  • Genetic susceptibility--molecular epidemiology of head and neck cancer. 
  • Genetics of multiple sclerosis. 
  • Genome-wide association study of white blood cell count in 16,388 African Americans: the continental origins and genetic epidemiology network (COGENT). 
  • Genome-wide meta-analyses identify multiple loci associated with smoking behavior. 
  • Genomic Analysis of Multidrug-Resistant Escherichia coli from North Carolina Community Hospitals: Ongoing Circulation of CTX-M-Producing ST131-H30Rx and ST131-H30R1 Strains. 
  • Genomic sequencing is required for identification of tuberculosis transmission in Hawaii. 
  • Genotypic and Spatial Analysis of Mycobacterium tuberculosis Transmission in a High-Incidence Urban Setting. 
  • Genotypic characteristics of Staphylococcus aureus isolates from a multinational trial of complicated skin and skin structure infections. 
  • Global and regional epidemiology of HIV-1 recombinants in 1990-2015: a systematic review and global survey. 
  • HIV Transmission Patterns Among Immigrant Latinos Illuminated by the Integration of Phylogenetic and Migration Data. 
  • HIV type 1 subtypes in Malaysia, determined with serologic assays: 1992-1996. 
  • Haplotype associations with quantitative traits in the presence of complex multilocus and heterogeneous effects. 
  • Haplotype-based analysis: a summary of GAW16 Group 4 analysis. 
  • How frailty models can be used for evaluating longevity limits: taking advantage of an interdisciplinary approach. 
  • How heritable is individual susceptibility to death? The results of an analysis of survival data on Danish, Swedish and Finnish twins. 
  • Human exposure to selected animal neurocarcinogens: a biomarker-based assessment and implications for brain tumor epidemiology. 
  • Identification of a W variant outbreak of Mycobacterium tuberculosis via population-based molecular epidemiology. 
  • Lack of genetic differentiation between two geographically diverse samples of Candida albicans isolated from patients infected with human immunodeficiency virus. 
  • Leveraging Phylogenetics to Understand HIV Transmission and Partner Notification Networks. 
  • Manganese superoxide dismutase Ala-9Val polymorphism and risk of breast cancer in a population-based case-control study of African Americans and whites. 
  • Mathematical modeling: epidemiology meets systems biology. 
  • Molecular epidemiology and tuberculosis control. 
  • Molecular epidemiology of Staphylococcus aureus mastitis in dairy heifers. 
  • Molecular evidence that the range of the Vancouver Island outbreak of Cryptococcus gattii infection has expanded into the Pacific Northwest in the United States. 
  • Molecular malaria epidemiology: mapping and burden estimates for the Democratic Republic of the Congo, 2007. 
  • Multicentre surveillance of the prevalence and molecular epidemiology of macrolide resistance among pharyngeal isolates of group A streptococci in the USA. 
  • Multilocus microsatellite genotyping array for investigation of genetic epidemiology of Pneumocystis jirovecii. 
  • Multiple loci are associated with white blood cell phenotypes. 
  • Multiplex 5' nuclease quantitative real-time PCR for clinical diagnosis of malaria and species-level identification and epidemiologic evaluation of malaria-causing parasites, including Plasmodium knowlesi. 
  • Outbreak of Invasive Wound Mucormycosis in a Burn Unit Due to Multiple Strains of Mucor circinelloides f. circinelloides Resolved by Whole-Genome Sequencing. 
  • Polymorphisms at newly identified lipid-associated loci are associated with blood lipids and cardiovascular disease in an Asian Malay population. 
  • Polymorphisms in microRNA targets: a gold mine for molecular epidemiology. 
  • Polymorphisms of the FAS and FAS ligand genes associated with risk of cutaneous malignant melanoma. 
  • Pooled deep sequencing of Plasmodium falciparum isolates: an efficient and scalable tool to quantify prevailing malaria drug-resistance genotypes. 
  • Prediction of HIV Transmission Cluster Growth With Statewide Surveillance Data. 
  • Rapid reporting of cancer incidence in a population-based study of breast cancer: one constructive use of a central cancer registry. 
  • RecDraw: a software package for the representation of HIV-1 recombinant structures. 
  • Reduced expression levels of nucleotide excision repair genes in lung cancer: a case-control analysis. 
  • Surveillance of carbapenem-resistant Klebsiella pneumoniae: tracking molecular epidemiology and outcomes through a regional network. 
  • Susceptibility locus for clinical and subclinical coronary artery disease at chromosome 9p21 in the multi-ethnic ADVANCE study. 
  • The Carolina Breast Cancer Study: integrating population-based epidemiology and molecular biology. 
  • The Glioma International Case-Control Study: A Report From the Genetic Epidemiology of Glioma International Consortium. 
  • The changing molecular epidemiology of HIV type 1 among northern Thai drug users, 1999 to 2002. 
  • The clinical and molecular epidemiology of community- and healthcare-acquired rotavirus gastroenteritis. 
  • The genetic epidemiology of multiple sclerosis. 
  • The increase in global HIV epidemics in MSM. 
  • The role of DNA repair capacity in susceptibility to lung cancer: a review. 
  • Use of pathway information in molecular epidemiology. 
  • Whole genome sequencing identifies circulating Beijing-lineage Mycobacterium tuberculosis strains in Guatemala and an associated urban outbreak. 
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  Keywords of People

  • Akinyemiju, Tomi, Associate Professor in Population Health Sciences, Obstetrics and Gynecology
  • Hill, Sherika N, Adjunct Assistant Professor in the Department of Psychiatry and Behavioral Sciences, Psychiatry, Child & Family Mental Health & Community Psychiatry
  • Moorman, Patricia Gripka, Professor Emeritus in Family Medicine and Community Health, Duke Cancer Institute
  • Ostrom, Quinn, Assistant Professor in Neurosurgery, Neurosurgery, Neuro-Oncology
  • Pasquale, Dana Kristine, Assistant Professor in Population Health Sciences, Population Health Sciences