Presynaptic Terminals

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  Subject Areas on Research

  • A Role for Dystonia-Associated Genes in Spinal GABAergic Interneuron Circuitry. 
  • A mesocortical dopamine circuit enables the cultural transmission of vocal behaviour. 
  • A ubiquitin E2 variant protein acts in axon termination and synaptogenesis in Caenorhabditis elegans. 
  • Acute 5-HT reuptake blockade potentiates human amygdala reactivity. 
  • Additive and synergistic effects of fetal nicotine and dexamethasone exposure on cholinergic synaptic function in adolescence and adulthood: Implications for the adverse consequences of maternal smoking and pharmacotherapy of preterm delivery. 
  • Alterations of serotonin synaptic proteins in brain regions of neonatal Rhesus monkeys exposed to perinatal environmental tobacco smoke. 
  • Altered localization of choline transporter sites in the mouse hippocampus after prenatal heroin exposure. 
  • Altered morphology of hippocampal dentate granule cell presynaptic and postsynaptic terminals following conditional deletion of TrkB. 
  • Antidromic propagation of action potentials in branched axons: implications for the mechanisms of action of deep brain stimulation. 
  • Apolipoprotein E level and cholesterol are associated with reduced synaptic amyloid beta in Alzheimer's disease and apoE TR mouse cortex. 
  • Autoimmunity to munc-18 in Rasmussen's encephalitis. 
  • Autoreceptor presynaptic control of dopamine release from striatum is lost at early stages of manganese poisoning. 
  • Biophysically realistic neuron models for simulation of cortical stimulation. 
  • Burst-Dependent Bidirectional Plasticity in the Cerebellum Is Driven by Presynaptic NMDA Receptors. 
  • Cocaine increases dopamine release by mobilization of a synapsin-dependent reserve pool. 
  • Cocaine increases stimulated dopamine release more in periadolescent than adult rats. 
  • Conditional expression in corticothalamic efferents reveals a developmental role for nicotinic acetylcholine receptors in modulation of passive avoidance behavior. 
  • Developmental exposure to terbutaline and chlorpyrifos, separately or sequentially, elicits presynaptic serotonergic hyperactivity in juvenile and adolescent rats. 
  • Differential activity-dependent, homeostatic plasticity of two neocortical inhibitory circuits. 
  • Differential dynamics and activity-dependent regulation of alpha- and beta-neurexins at developing GABAergic synapses. 
  • Differential wiring of local excitatory and inhibitory synaptic inputs to islet cells in rat spinal lamina II demonstrated by laser scanning photostimulation. 
  • Distribution of glucagon-like peptide-1 immunoreactivity in the hypothalamic paraventricular and supraoptic nuclei. 
  • Diurnal changes in exocytosis and the number of synaptic ribbons at active zones of an ON-type bipolar cell terminal. 
  • Dopamine attenuates evoked inhibitory synaptic currents in central amygdala neurons. 
  • Dopaminergic control of corticostriatal long-term synaptic depression in medium spiny neurons is mediated by cholinergic interneurons. 
  • Expanding views of presynaptic terminals: new findings from Caenorhabditis elegans. 
  • Experience and activity-dependent maturation of perisomatic GABAergic innervation in primary visual cortex during a postnatal critical period. 
  • Expression of a variant form of the glutamate transporter GLT1 in neuronal cultures and in neurons and astrocytes in the rat brain. 
  • Fast endocytosis is inhibited by GABA-mediated chloride influx at a presynaptic terminal. 
  • Fetal and adolescent nicotine administration: effects on CNS serotonergic systems. 
  • GABA transporters regulate a standing GABAC receptor-mediated current at a retinal presynaptic terminal. 
  • Hebb's dream: the resurgence of cell assemblies. 
  • Identifying local and descending inputs for primary sensory neurons. 
  • Is neural development Darwinian? 
  • Lactate uptake contributes to the NAD(P)H biphasic response and tissue oxygen response during synaptic stimulation in area CA1 of rat hippocampal slices. 
  • Lambert-Eaton myasthenic syndrome: clinical diagnosis, immune-mediated mechanisms, and update on therapies. 
  • Lambert-Eaton myasthenic syndrome: pathogenesis and treatment. 
  • Mechanistic Insights into Sympathetic Neuronal Regeneration: Multitracer Molecular Imaging of Catecholamine Handling After Cardiac Transplantation. 
  • Multiple roles for the active zone protein RIM1alpha in late stages of neurotransmitter release. 
  • Multiple sources of internal calcium stores mediate ethanol-induced presynaptic inhibitory GABA release in the central nucleus of the amygdala in mice. 
  • Munc13-1 is required for presynaptic long-term potentiation. 
  • Neuregulin-1 enhances depolarization-induced GABA release. 
  • Neuropeptide Y regulates recurrent mossy fiber synaptic transmission less effectively in mice than in rats: Correlation with Y2 receptor plasticity. 
  • Neurotensin receptor 1-biased ligand attenuates neurotensin-mediated excitation of ventral tegmental area dopamine neurons and dopamine release in the nucleus accumbens. 
  • PDAPP; YFP double transgenic mice: a tool to study amyloid-beta associated changes in axonal, dendritic, and synaptic structures. 
  • Permanent, sex-selective effects of prenatal or adolescent nicotine exposure, separately or sequentially, in rat brain regions: indices of cholinergic and serotonergic synaptic function, cell signaling, and neural cell number and size at 6 months of age. 
  • Persistent cholinergic presynaptic deficits after neonatal chlorpyrifos exposure. 
  • Prenatal chlorpyrifos exposure elicits presynaptic serotonergic and dopaminergic hyperactivity at adolescence: critical periods for regional and sex-selective effects. 
  • Presynaptic BK channels modulate ethanol-induced enhancement of GABAergic transmission in the rat central amygdala nucleus. 
  • Presynaptic Disorders: Lambert-Eaton Myasthenic Syndrome and Botulism. 
  • Presynaptic Inputs to Any CNS Projection Neuron Identified by Dual Recombinant Virus Infection. 
  • Presynaptic homeostasis at CNS nerve terminals compensates for lack of a key Ca2+ entry pathway. 
  • Presynaptic inhibition of spinal sensory feedback ensures smooth movement. 
  • Reciprocal connections between the zona incerta and the pretectum and superior colliculus of the cat. 
  • Recovery of presynaptic dopaminergic functioning in rats treated with neurotoxic doses of methamphetamine. 
  • Regulators of G protein signaling proteins as determinants of the rate of desensitization of presynaptic calcium channels. 
  • Retrograde influence of muscle fibers on their innervation revealed by a novel marker for slow motoneurons. 
  • SHANK3 Deficiency Impairs Heat Hyperalgesia and TRPV1 Signaling in Primary Sensory Neurons. 
  • Sensory neuron signaling to the brain: properties of transmitter release from olfactory nerve terminals. 
  • Serotonin synthesis, release and reuptake in terminals: a mathematical model. 
  • Sodium-dependent proline and glutamate uptake by hippocampal synaptosomes during postnatal development. 
  • Structural plasticity of dentate granule cell mossy fibers during the development of limbic epilepsy. 
  • Synapsins differentially control dopamine and serotonin release. 
  • Synaptic activation of presynaptic glutamate transporter currents in nerve terminals. 
  • Synaptic cleft acidification and modulation of short-term depression by exocytosed protons in retinal bipolar cells. 
  • Synaptic integration of olfactory information in mouse anterior olfactory nucleus. 
  • Synaptotagmin 7 functions as a Ca2+-sensor for synaptic vesicle replenishment. 
  • Telencephalic neurons monosynaptically link brainstem and forebrain premotor networks necessary for song. 
  • Temporal specific patterns of semaphorin gene expression in rat brain after kainic acid-induced status epilepticus. 
  • The development of excitatory synapses in cultured spinal neurons. 
  • The role of protein synthesis in striatal long-term depression. 
  • Ultrastructural abnormalities in CA1 hippocampus caused by deletion of the actin regulator WAVE-1. 
  • Vesicular zinc promotes presynaptic and inhibits postsynaptic long-term potentiation of mossy fiber-CA3 synapse. 
  • miR-27b shapes the presynaptic transcriptome and influences neurotransmission by silencing the polycomb group protein Bmi1. 
  • κ-Opioid receptors in the central amygdala regulate ethanol actions at presynaptic GABAergic sites. 
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  Keywords of People

  • Calakos, Nicole, Lincoln Financial Group Distinguished Professor of Neurobiology, Duke Science & Society
  • Soderling, Scott Haydn, George Barth Geller Distinguished Professor of Molecular Biology, Cell Biology