Virus Latency

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  Subject Areas on Research

  • A neuron-specific host microRNA targets herpes simplex virus-1 ICP0 expression and promotes latency. 
  • A viral microRNA cluster strongly potentiates the transforming properties of a human herpesvirus. 
  • AIDS-related cytomegalovirus retinitis: lessons from the laboratory. 
  • Administration of vorinostat disrupts HIV-1 latency in patients on antiretroviral therapy. 
  • Analysis of human alphaherpesvirus microRNA expression in latently infected human trigeminal ganglia. 
  • Analysis of rhesus rhadinovirus microRNAs expressed in virus-induced tumors from infected rhesus macaques. 
  • Combination therapy with anti-HIV-1 antibodies maintains viral suppression. 
  • Curing HIV: Seeking to Target and Clear Persistent Infection. 
  • Current issues in global tuberculosis control. 
  • Dual-Affinity Re-Targeting proteins direct T cell-mediated cytolysis of latently HIV-infected cells. 
  • EBV BART MicroRNAs Target Multiple Pro-apoptotic Cellular Genes to Promote Epithelial Cell Survival. 
  • Enhanced green fluorescent protein as a marker for localizing murine cytomegalovirus in acute and latent infection. 
  • Epigenetic and epitranscriptomic regulation of viral replication. 
  • Epstein-Barr virus induces global changes in cellular mRNA isoform usage that are important for the maintenance of latency. 
  • Epstein-Barr virus microRNAs are evolutionarily conserved and differentially expressed. 
  • Expression of a murine cytomegalovirus early-late protein in "latently" infected mice. 
  • Genetic complexity in the replication-competent latent HIV reservoir increases with untreated infection duration in infected youth. 
  • Gnidimacrin, a Potent Anti-HIV Diterpene, Can Eliminate Latent HIV-1 Ex Vivo by Activation of Protein Kinase C β. 
  • HIV reservoirs: the new frontier. 
  • HIV-1 extrachromosomal 2-LTR circular DNA is long-lived in human macrophages. 
  • Heterologous immunity triggered by a single, latent virus in Mus musculus: combined costimulation- and adhesion- blockade decrease rejection. 
  • High levels of CD2 expression identify HIV-1 latently infected resting memory CD4+ T cells in virally suppressed subjects. 
  • Human papillomavirus genotype 31 does not express detectable microRNA levels during latent or productive virus replication. 
  • Humoral and Innate Antiviral Immunity as Tools to Clear Persistent HIV Infection. 
  • Identification of Host Biomarkers of Epstein-Barr Virus Latency IIb and Latency III. 
  • Identification of viral microRNAs expressed in human sacral ganglia latently infected with herpes simplex virus 2. 
  • Improved killing of HIV-infected cells using three neutralizing and non-neutralizing antibodies. 
  • In-depth analysis of Kaposi's sarcoma-associated herpesvirus microRNA expression provides insights into the mammalian microRNA-processing machinery. 
  • Interleukin-15-Stimulated Natural Killer Cells Clear HIV-1-Infected Cells following Latency Reversal Ex Vivo. 
  • Kaposi's sarcoma-associated herpesvirus expresses an array of viral microRNAs in latently infected cells. 
  • Latency reversal and viral clearance to cure HIV-1. 
  • MicroRNAs expressed by herpes simplex virus 1 during latent infection regulate viral mRNAs. 
  • Mouse cytomegalovirus reactivation in severe combined immune deficient mice after implantation of latently infected salivary gland. 
  • On the role of human herpesvirus 6 in viral latency in nervous tissue and in cerebral lymphoma. 
  • Persistently adenovirus-infected lymphoid cells express microRNAs derived from the viral VAI and especially VAII RNA. 
  • Proliferation of HIV-infected renal epithelial cells following virus acquisition from infected macrophages. 
  • Prolonged clinical latency and survival of macaques given a whole inactivated simian immunodeficiency virus vaccine. 
  • Risk factors influencing antibody responses to Kaposi's sarcoma-associated herpesvirus latent and lytic antigens in patients under antiretroviral therapy. 
  • SMAC Mimetic Plus Triple-Combination Bispecific HIVxCD3 Retargeting Molecules in SHIV.C.CH505-Infected, Antiretroviral Therapy-Suppressed Rhesus Macaques. 
  • Single-Cell Analysis of Quiescent HIV Infection Reveals Host Transcriptional Profiles that Regulate Proviral Latency. 
  • Synthesis and Structure-Activity Relationship Correlations of Gnidimacrin Derivatives as Potent HIV-1 Inhibitors and HIV Latency Reversing Agents. 
  • The Human Immunodeficiency Virus 1 ASP RNA promotes viral latency by recruiting the Polycomb Repressor Complex 2 and promoting nucleosome assembly. 
  • The role of microRNAs in Epstein-Barr virus latency and lytic reactivation. 
  • The viral and cellular microRNA targetome in lymphoblastoid cell lines. 
  • Three months of rifapentine and isoniazid for latent tuberculosis infection. 
  • To be or not IIb: a multi-step process for Epstein-Barr virus latency establishment and consequences for B cell tumorigenesis. 
  • beta-Endorphin enhances the replication of neurotropic human immunodeficiency virus in fetal perivascular microglia. 
  • c-Myc Represses Transcription of Epstein-Barr Virus Latent Membrane Protein 1 Early after Primary B Cell Infection. 
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  Keywords of People

  • Luftig, Micah Alan, Associate Professor of Molecular Genetics and Microbiology, Immunology