Virus Latency

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  Subject Areas on Research

  • A new model of Epstein-Barr virus infection reveals an important role for early lytic viral protein expression in the development of lymphomas. 
  • ADAP1 promotes latent HIV-1 reactivation by selectively tuning KRAS-ERK-AP-1 T cell signaling-transcriptional axis. 
  • AIDS-related cytomegalovirus retinitis: lessons from the laboratory. 
  • Administration of vorinostat disrupts HIV-1 latency in patients on antiretroviral therapy. 
  • Combination therapy with anti-HIV-1 antibodies maintains viral suppression. 
  • Curing HIV: Seeking to Target and Clear Persistent Infection. 
  • Current issues in global tuberculosis control. 
  • Dual-Affinity Re-Targeting proteins direct T cell-mediated cytolysis of latently HIV-infected cells. 
  • Enhanced green fluorescent protein as a marker for localizing murine cytomegalovirus in acute and latent infection. 
  • Epstein-Barr virus induces global changes in cellular mRNA isoform usage that are important for the maintenance of latency. 
  • Establishment, Persistence, and Reactivation of Latent HIV-1 Infection in Renal Epithelial Cells. 
  • Evidence of Epstein-Barr virus heterogeneous gene expression in adult lung transplant recipients with posttransplant lymphoproliferative disorder. 
  • Expression of a murine cytomegalovirus early-late protein in "latently" infected mice. 
  • Gnidimacrin, a Potent Anti-HIV Diterpene, Can Eliminate Latent HIV-1 Ex Vivo by Activation of Protein Kinase C β. 
  • HIV-1 Proviral Transcription and Latency in the New Era. 
  • HIV-1 extrachromosomal 2-LTR circular DNA is long-lived in human macrophages. 
  • Herpes Simplex Virus 1 Infection of Tree Shrews Differs from That of Mice in the Severity of Acute Infection and Viral Transcription in the Peripheral Nervous System. 
  • Heterologous immunity triggered by a single, latent virus in Mus musculus: combined costimulation- and adhesion- blockade decrease rejection. 
  • Host Cell Redox Alterations Promote Latent HIV-1 Reactivation through Atypical Transcription Factor Cooperativity. 
  • Humoral and Innate Antiviral Immunity as Tools to Clear Persistent HIV Infection. 
  • Identification of Host Biomarkers of Epstein-Barr Virus Latency IIb and Latency III. 
  • Improved killing of HIV-infected cells using three neutralizing and non-neutralizing antibodies. 
  • Interleukin-15-Stimulated Natural Killer Cells Clear HIV-1-Infected Cells following Latency Reversal Ex Vivo. 
  • Latency reversal and viral clearance to cure HIV-1. 
  • Mouse cytomegalovirus reactivation in severe combined immune deficient mice after implantation of latently infected salivary gland. 
  • Mouse strain differences in the chemokine response to acute lung infection with a murine gammaherpesvirus. 
  • On the role of human herpesvirus 6 in viral latency in nervous tissue and in cerebral lymphoma. 
  • Open conformers of HLA-F are high-affinity ligands of the activating NK-cell receptor KIR3DS1. 
  • Proliferation of HIV-infected renal epithelial cells following virus acquisition from infected macrophages. 
  • Prolonged clinical latency and survival of macaques given a whole inactivated simian immunodeficiency virus vaccine. 
  • Regulation of human retroviral latency by the NF-kappa B/I kappa B family: inhibition of human immunodeficiency virus replication by I kappa B through a Rev-dependent mechanism. 
  • Risk factors influencing antibody responses to Kaposi's sarcoma-associated herpesvirus latent and lytic antigens in patients under antiretroviral therapy. 
  • SARS-CoV-2 and HIV-1 - a tale of two vaccines. 
  • SMAC Mimetic Plus Triple-Combination Bispecific HIVxCD3 Retargeting Molecules in SHIV.C.CH505-Infected, Antiretroviral Therapy-Suppressed Rhesus Macaques. 
  • Single-Cell Analysis of Quiescent HIV Infection Reveals Host Transcriptional Profiles that Regulate Proviral Latency. 
  • Sleep and fatigue in mice infected with murine gammaherpesvirus 68. 
  • Stable Latent HIV Infection and Low-level Viremia Despite Treatment With the Broadly Neutralizing Antibody VRC07-523LS and the Latency Reversal Agent Vorinostat. 
  • Synthesis and Structure-Activity Relationship Correlations of Gnidimacrin Derivatives as Potent HIV-1 Inhibitors and HIV Latency Reversing Agents. 
  • The role of microRNAs in Epstein-Barr virus latency and lytic reactivation. 
  • The viral and cellular microRNA targetome in lymphoblastoid cell lines. 
  • Three months of rifapentine and isoniazid for latent tuberculosis infection. 
  • To be or not IIb: a multi-step process for Epstein-Barr virus latency establishment and consequences for B cell tumorigenesis. 
  • Transcriptional Circuit Fragility Influences HIV Proviral Fate. 
  • beta-Endorphin enhances the replication of neurotropic human immunodeficiency virus in fetal perivascular microglia. 
  • c-Myc Represses Transcription of Epstein-Barr Virus Latent Membrane Protein 1 Early after Primary B Cell Infection. 
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  Keywords of People

  • Luftig, Micah Alan, Professor of Molecular Genetics and Microbiology, Cell Biology