Exfoliation Syndrome

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  Subject Areas on Research

  • A common variant mapping to CACNA1A is associated with susceptibility to exfoliation syndrome. 
  • Analysis of LOXL1 polymorphisms in a United States population with pseudoexfoliation glaucoma. 
  • Association of Rare CYP39A1 Variants With Exfoliation Syndrome Involving the Anterior Chamber of the Eye. 
  • Common variants at 9p21 and 8q22 are associated with increased susceptibility to optic nerve degeneration in glaucoma. 
  • Composition of Exfoliation Material. 
  • Corneal thickness and applanation pressure. 
  • Differentially expressed microRNAs in the aqueous humor of patients with exfoliation glaucoma or primary open-angle glaucoma. 
  • Genetic association study of exfoliation syndrome identifies a protective rare variant at LOXL1 and five new susceptibility loci. 
  • Genetic variants and cellular stressors associated with exfoliation syndrome modulate promoter activity of a lncRNA within the LOXL1 locus. 
  • Genetics of adult glaucoma. 
  • Genetics of pseudoexfoliation syndrome. 
  • Glaucoma genetics. 
  • High failure rate associated with 180 degrees selective laser trabeculoplasty. 
  • Identification and activity of the functional complex between hnRNPL and the pseudoexfoliation syndrome-associated lncRNA, LOXL1-AS1. 
  • Immunogold study of non-collagenous matrix components in normal and exfoliative iris. 
  • Integral role for lysyl oxidase-like-1 in conventional outflow tissue function and behavior. 
  • January consultation # 7. 
  • LOXL1 expression in lens capsule tissue specimens from individuals with pseudoexfoliation syndrome and glaucoma. 
  • Lack of association between LOXL1 gene polymorphisms and primary open angle glaucoma in the Saudi Arabian population. 
  • Lack of association between LOXL1 variants and primary open-angle glaucoma in three different populations. 
  • Major LOXL1 risk allele is reversed in exfoliation glaucoma in a black South African population. 
  • Major review: Exfoliation syndrome; advances in disease genetics, molecular biology, and epidemiology. 
  • Molecular genetics in glaucoma. 
  • Morphology of iris vasculopathy in exfoliation glaucoma. 
  • Myocilin levels in primary open-angle glaucoma and pseudoexfoliation glaucoma human aqueous humor. 
  • Prevalence of pseudoexfoliation in Malay population in Singapore. 
  • The role of lysyl oxidase-like 1 DNA copy number variants in exfoliation glaucoma. 
  • lncRNAs, DNA Methylation, and the Pathobiology of Exfoliation Glaucoma. 
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  Keywords of People

  • Liu, Katy, Assistant Professor of Ophthalmology, Ophthalmology, Glaucoma
  • Liu, Yutao, Adjunct Assistant Professor in the Department of Medicine, Medicine, Medical Genetics
  • Stinnett, Sandra Sue, Associate Professor of Biostatistics & Bioinformatics, Biostatistics & Bioinformatics