Retinal Rod Photoreceptor Cells
Subject Areas on Research
- Absence of synaptic regulation by phosducin in retinal slices.
- Absence of the RGS9.Gbeta5 GTPase-activating complex in photoreceptors of the R9AP knockout mouse.
- Activation of Rod Input in a Model of Retinal Degeneration Reverses Retinal Remodeling and Induces Formation of Functional Synapses and Recovery of Visual Signaling in the Adult Retina.
- Altered light responses of single rod photoreceptors in transgenic pigs expressing P347L or P347S rhodopsin.
- ApoER2 function in the establishment and maintenance of retinal synaptic connectivity.
- Cell type-specific changes in retinal ganglion cell function induced by rod death and cone reorganization in rats.
- Connexin 36 and rod bipolar cell independent rod pathways drive retinal ganglion cells and optokinetic reflexes.
- Deletion of the phosphatase INPP5E in the murine retina impairs photoreceptor axoneme formation and prevents disc morphogenesis.
- Deletion of the transmembrane protein Prom1b in zebrafish disrupts outer-segment morphogenesis and causes photoreceptor degeneration.
- Discs of mammalian rod photoreceptors form through the membrane evagination mechanism.
- Disrupting the ciliary gradient of active Arl3 affects rod photoreceptor nuclear migration.
- Distinct and atypical intrinsic and extrinsic cell death pathways between photoreceptor cell types upon specific ablation of Ranbp2 in cone photoreceptors.
- Early loss of synaptic protein PSD-95 from rod terminals of rhodopsin P347L transgenic porcine retina.
- Ectopic synaptogenesis in the mammalian retina caused by rod photoreceptor-specific mutations.
- Electrostatic and lipid anchor contributions to the interaction of transducin with membranes: mechanistic implications for activation and translocation.
- FGF signaling regulates rod photoreceptor cell maintenance and regeneration in zebrafish.
- Genetic dissection of rod and cone pathways in the dark-adapted mouse retina.
- Growth factor receptor-bound protein 14 undergoes light-dependent intracellular translocation in rod photoreceptors: functional role in retinal insulin receptor activation.
- High-sensitivity rod photoreceptor input to the blue-yellow color opponent pathway in macaque retina.
- In Situ Gene Therapy via AAV-CRISPR-Cas9-Mediated Targeted Gene Regulation.
- Increased proteasomal activity supports photoreceptor survival in inherited retinal degeneration.
- Knockout of Nr2e3 prevents rod photoreceptor differentiation and leads to selective L-/M-cone photoreceptor degeneration in zebrafish.
- Lifetime regulation of G protein-effector complex: emerging importance of RGS proteins.
- Like night and day: rods and cones have different pigment regeneration pathways.
- Massive light-driven translocation of transducin between the two major compartments of rod cells: a novel mechanism of light adaptation.
- Mechanisms regulating variability of the single photon responses of mammalian rod photoreceptors.
- Mechanistic basis for the failure of cone transducin to translocate: why cones are never blinded by light.
- Nonlinear signal transfer from mouse rods to bipolar cells and implications for visual sensitivity.
- Onset of feedback reactions underlying vertebrate rod photoreceptor light adaptation.
- Optimal processing of photoreceptor signals is required to maximize behavioural sensitivity.
- Oxidative damage is a potential cause of cone cell death in retinitis pigmentosa.
- PRCD Is a Small Disc-Specific Rhodopsin-Binding Protein of Unknown Function.
- Phosducin facilitates light-driven transducin translocation in rod photoreceptors. Evidence from the phosducin knockout mouse.
- Phosducin regulates the expression of transducin betagamma subunits in rod photoreceptors and does not contribute to phototransduction adaptation.
- Phosphoinositide Profile of the Mouse Retina.
- Phosphorylation of G protein-coupled receptor kinase 1 (GRK1) is regulated by light but independent of phototransduction in rod photoreceptors.
- Photoreceptor Disc Enclosure Is Tightly Controlled by Peripherin-2 Oligomerization.
- Probing Proteostatic Stress in Degenerating Photoreceptors Using Two Complementary In Vivo Reporters of Proteasomal Activity.
- Properties of multivesicular release from mouse rod photoreceptors support transmission of single-photon responses.
- Proteasome overload is a common stress factor in multiple forms of inherited retinal degeneration.
- RGS expression rate-limits recovery of rod photoresponses.
- Recoverin improves rod-mediated vision by enhancing signal transmission in the mouse retina.
- Recoverin undergoes light-dependent intracellular translocation in rod photoreceptors.
- Relating Retinal Morphology and Function in Aging and Early to Intermediate Age-related Macular Degeneration Subjects.
- Relative contributions of rod and cone bipolar cell inputs to AII amacrine cell light responses in the mouse retina.
- Retinal rod photoreceptor-specific gene mutation perturbs cone pathway development.
- Rhodopsin phosphorylation: from terminating single photon responses to photoreceptor dark adaptation.
- Robust cone-mediated signaling persists late into rod photoreceptor degeneration.
- Rod mutations associated with MYH9-related disorders disrupt nonmuscle myosin-IIA assembly.
- Temporal resolution of single-photon responses in primate rod photoreceptors and limits imposed by cellular noise.
- The Effects of Diabetic Retinopathy and Pan-Retinal Photocoagulation on Photoreceptor Cell Function as Assessed by Dark Adaptometry.
- The F220C and F45L rhodopsin mutations identified in retinitis pigmentosa patients do not cause pathology in mice.
- The cloning of GRK7, a candidate cone opsin kinase, from cone- and rod-dominant mammalian retinas.
- The gain of rod phototransduction: reconciliation of biochemical and electrophysiological measurements.
- The regulation of the cGMP-binding cGMP phosphodiesterase by proteins that are immunologically related to gamma subunit of the photoreceptor cGMP phosphodiesterase.
- The retinitis pigmentosa GTPase regulator (RPGR) interacts with novel transport-like proteins in the outer segments of rod photoreceptors.
- Transducin gamma-subunit sets expression levels of alpha- and beta-subunits and is crucial for rod viability.
- Transducin translocation in rods is triggered by saturation of the GTPase-activating complex.
- Transducin β-Subunit Can Interact with Multiple G-Protein γ-Subunits to Enable Light Detection by Rod Photoreceptors.
- Two temporal phases of light adaptation in retinal rods.
- Ubiquitylation of the transducin betagamma subunit complex. Regulation by phosducin.