Myogenic Regulatory Factors
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Subject Areas on Research
- A protein encoded within the Down syndrome critical region is enriched in striated muscles and inhibits calcineurin signaling.
- Activation of MEF2 by muscle activity is mediated through a calcineurin-dependent pathway.
- Calmodulin-dependent protein kinase IV regulates nuclear export of Cabin1 during T-cell activation.
- Collaborative interactions between MEF-2 and Sp1 in muscle-specific gene regulation.
- Electrical stimulation of neonatal cardiac myocytes activates the NFAT3 and GATA4 pathways and up-regulates the adenylosuccinate synthetase 1 gene.
- Exercise can prevent and reverse the severity of hypertrophic cardiomyopathy.
- Inefficient reprogramming of fibroblasts into cardiomyocytes using Gata4, Mef2c, and Tbx5.
- Interaction and functional collaboration of p300/CBP and bHLH proteins in muscle and B-cell differentiation.
- MEF2 responds to multiple calcium-regulated signals in the control of skeletal muscle fiber type.
- Members of the myocyte enhancer factor 2 transcription factor family differentially regulate Bdnf transcription in response to neuronal depolarization.
- MyoD, modularity, and myogenesis: conservation of regulators and redundancy in C. elegans.
- Nerve activity-dependent modulation of calcineurin signaling in adult fast and slow skeletal muscle fibers.
- Parathyroid hormone-related peptide represses chondrocyte hypertrophy through a protein phosphatase 2A/histone deacetylase 4/MEF2 pathway.
- Regulation of MEF2 by histone deacetylase 4- and SIRT1 deacetylase-mediated lysine modifications.
- Synergistic interactions between heterologous upstream activation elements and specific TATA sequences in a muscle-specific promoter.
- The deacetylase HDAC4 controls myocyte enhancing factor-2-dependent structural gene expression in response to neural activity.
- The neurodegenerative disease protein ataxin-1 antagonizes the neuronal survival function of myocyte enhancer factor-2.