Receptors, Prostaglandin E

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  Subject Areas on Research

  • A role for G(z) in pancreatic islet beta-cell biology. 
  • Activation of the murine EP3 receptor for PGE2 inhibits cAMP production and promotes platelet aggregation. 
  • Coupling of COX-1 to mPGES1 for prostaglandin E2 biosynthesis in the murine mammary gland. 
  • E-prostanoid-3 receptors mediate the proinflammatory actions of prostaglandin E2 in acute cutaneous inflammation. 
  • Homologous desensitization of adenylate cyclase is associated with phosphorylation of the beta-adrenergic receptor. 
  • Identification of specific EP receptors responsible for the hemodynamic effects of PGE2. 
  • Phosphatase and tensin homologue on chromosome 10 (PTEN) directs prostaglandin E2-mediated fibroblast responses via regulation of E prostanoid 2 receptor expression. 
  • Receptors and signaling mechanisms required for prostaglandin E2-mediated regulation of mast cell degranulation and IL-6 production. 
  • Receptors for prostaglandin E(2) that regulate cellular immune responses in the mouse. 
  • Reproductive failure and reduced blood pressure in mice lacking the EP2 prostaglandin E2 receptor. 
  • Role of EP(2) and EP(3) PGE(2) receptors in control of murine renal hemodynamics. 
  • Sufficient progesterone-priming prior to estradiol stimulation is required for optimal induction of the cervical prostaglandin system in pregnant sheep at 0.7 gestations. 
  • The EP4 receptor for prostaglandin E2 in glomerular disease: a good receptor turned bad? 
  • The prostaglandin E2 EP1 receptor mediates pain perception and regulates blood pressure. 
  • The prostaglandin receptor EP4 triggers remodelling of the cardiovascular system at birth.