Receptors, AMPA

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  Subject Areas on Research

  • "Silent" NMDA Synapses Enhance Motion Sensitivity in a Mature Retinal Circuit. 
  • 7, 8-Dihydroxyflavone induces synapse expression of AMPA GluA1 and ameliorates cognitive and spine abnormalities in a mouse model of fragile X syndrome. 
  • A unified model of the presynaptic and postsynaptic changes during LTP at CA1 synapses. 
  • AMPA receptor competitive antagonism reduces halothane MAC in rats. 
  • AMPA receptor-dependent clustering of synaptic NMDA receptors is mediated by Stargazin and NR2A/B in spinal neurons and hippocampal interneurons. 
  • Activity-dependent modulation of synaptic AMPA receptor accumulation. 
  • Acute spinal cord injury persistently reduces R/G RNA editing of AMPA receptors. 
  • Alterations of excitatory amino acid receptors in the brain of manganese-treated mice. 
  • Astrocytes "Chordinate" Synapse Maturation and Plasticity. 
  • Autoimmunity to munc-18 in Rasmussen's encephalitis. 
  • Autoreceptor regulation of glutamate and aspartate release from slices of the hippocampal CA1 area. 
  • B cells and epilepsy: the odd couple. 
  • Balanced synaptic impact via distance-dependent synapse distribution and complementary expression of AMPARs and NMDARs in hippocampal dendrites. 
  • Bradykinin enhances AMPA and NMDA receptor activity in spinal cord dorsal horn neurons by activating multiple kinases to produce pain hypersensitivity. 
  • Case-control association study of GRIA1, GRIA2 and GRIA4 polymorphisms in bipolar disorder. 
  • Characterization of multiple phosphorylation sites on the AMPA receptor GluR1 subunit. 
  • Circuit-selective striatal synaptic dysfunction in the Sapap3 knockout mouse model of obsessive-compulsive disorder. 
  • Consequences of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor blockade during status epilepticus in the developing brain. 
  • Cultured motor neurons possess calcium-permeable AMPA/kainate receptors. 
  • Deficiency of Shank2 causes mania-like behavior that responds to mood stabilizers. 
  • Development of intrinsic and synaptic properties in a forebrain nucleus essential to avian song learning. 
  • Differential expression of glutamate receptors in avian neural pathways for learned vocalization. 
  • Differing mechanisms for glutamate receptor aggregation on dendritic spines and shafts in cultured hippocampal neurons. 
  • Effects of neuromodulation in a cortical network model of object working memory dominated by recurrent inhibition. 
  • Effects of prenatal ethanol exposure on hippocampal ionotropic-quisqualate and kainate receptors. 
  • Ethanol inhibition of AMPA and kainate receptor-mediated depolarizations of hippocampal area CA1. 
  • Evidence of CNIH3 involvement in opioid dependence. 
  • Excitatory synaptic site heterogeneity during paired pulse plasticity in CA1 pyramidal cells in rat hippocampus in vitro. 
  • Expression of non-N-methyl-D-aspartate glutamate receptor subunits in the olfactory epithelium. 
  • GRIP: a synaptic PDZ domain-containing protein that interacts with AMPA receptors. 
  • Gating information by two-state membrane potential fluctuations. 
  • Genetic association study of individual symptoms in depression. 
  • Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia. 
  • GluR3 autoantibodies destroy neural cells in a complement-dependent manner modulated by complement regulatory proteins. 
  • Human genetics. Did radicals strike Lou Gehrig? 
  • Increased AMPA-sensitive quisqualate receptor binding and reduced NMDA receptor binding in epileptic human hippocampus. 
  • Independent sources of quantal variability at single glutamatergic synapses. 
  • Induction of c-fos mRNA by kindled seizures: complex relationship with neuronal burst firing. 
  • Influence of GRIA1, GRIA2 and GRIA4 polymorphisms on diagnosis and response to antipsychotic treatment in patients with schizophrenia. 
  • Influence of GRIA1, GRIA2 and GRIA4 polymorphisms on diagnosis and response to treatment in patients with major depressive disorder. 
  • Integrin-linked kinase is involved in cocaine sensitization by regulating PSD-95 and synapsin I expression and GluR1 Ser845 phosphorylation. 
  • Interaction between liprin-alpha and GIT1 is required for AMPA receptor targeting. 
  • Interactions between NMDA and AMPA glutamate receptor antagonists during halothane anesthesia in the rat. 
  • Investigation of possible epistatic interactions between GRIA2 and GRIA4 variants on clinical outcomes in patients with major depressive disorder. 
  • Kainate and quisqualate receptor autoradiography in rat brain after angular bundle kindling. 
  • Ketamine and ketamine metabolites as novel estrogen receptor ligands: Induction of cytochrome P450 and AMPA glutamate receptor gene expression. 
  • L-[3H]Glutamate binding to hippocampal synaptic membranes: two binding sites discriminated by their differing affinities for quisqualate. 
  • Long-term potentiation induced by theta frequency stimulation is regulated by a protein phosphatase-1-operated gate. 
  • Mechanisms of CaMKII action in long-term potentiation. 
  • Modulation of NMDA and AMPA-mediated synaptic transmission by CB1 receptors in frontal cortical pyramidal cells. 
  • Modulation of synaptic plasticity by antimanic agents: the role of AMPA glutamate receptor subunit 1 synaptic expression. 
  • Molecular mechanisms of glutamate receptor clustering at excitatory synapses. 
  • Nanoscale scaffolding domains within the postsynaptic density concentrate synaptic AMPA receptors. 
  • Neurabin/protein phosphatase-1 complex regulates dendritic spine morphogenesis and maturation. 
  • Neuronal pentraxin 1: a novel mediator of hypoxic-ischemic injury in neonatal brain. 
  • Post-transcriptional regulation of gene expression in hippocampal neurons by glutamate receptor activation. 
  • Postsynaptic positioning of endocytic zones and AMPA receptor cycling by physical coupling of dynamin-3 to Homer. 
  • Presynaptic and postsynaptic roles of NO, cGK, and RhoA in long-lasting potentiation and aggregation of synaptic proteins. 
  • Primary Blast Injury Depressed Hippocampal Long-Term Potentiation through Disruption of Synaptic Proteins. 
  • Properties of quantal transmission at CA1 synapses. 
  • Protein Crowding within the Postsynaptic Density Can Impede the Escape of Membrane Proteins. 
  • Quantification of spread of cerebellar long-term depression with chemical two-photon uncaging of glutamate. 
  • Rapid increase in clusters of presynaptic proteins at onset of long-lasting potentiation. 
  • Regulation of morphological postsynaptic silent synapses in developing hippocampal neurons. 
  • Regulation of synaptic strength by protein phosphatase 1. 
  • Release of glutamate and aspartate from CA1 synaptosomes: selective modulation of aspartate release by ionotropic glutamate receptor ligands. 
  • Reversal of cocaine-induced behavioral sensitization and associated phosphorylation of the NR2B and GluR1 subunits of the NMDA and AMPA receptors. 
  • Role of NMDA, non-NMDA, and GABA receptors in signal propagation in the amygdala formation. 
  • Rudimentary substrates for vocal learning in a suboscine. 
  • Sapap3 deletion causes mGluR5-dependent silencing of AMPAR synapses. 
  • Sensory neuron signaling to the brain: properties of transmitter release from olfactory nerve terminals. 
  • Stereological analysis of GluR2-immunoreactive hilar neurons in the pilocarpine model of temporal lobe epilepsy: correlation of cell loss with mossy fiber sprouting. 
  • Structural mechanism of glutamate receptor activation and desensitization. 
  • Structurally dissimilar antimanic agents modulate synaptic plasticity by regulating AMPA glutamate receptor subunit GluR1 synaptic expression. 
  • Subthreshold synaptic Ca2+ signalling in fine dendrites and spines of cerebellar Purkinje neurons. 
  • Synapse-specific downregulation of NMDA receptors by early experience: a critical period for plasticity of sensory input to olfactory cortex. 
  • Synaptic clustering of AMPA receptors by the extracellular immediate-early gene product Narp. 
  • Synaptic connections from multiple subfields contribute to granule cell hyperexcitability in hippocampal slice cultures. 
  • Synaptic mechanisms and network dynamics underlying spatial working memory in a cortical network model. 
  • Synaptically targeted narp plays an essential role in the aggregation of AMPA receptors at excitatory synapses in cultured spinal neurons. 
  • Targeting inhibition of GluR1 Ser845 phosphorylation with an RNA aptamer that blocks AMPA receptor trafficking. 
  • Thalamic relay of spontaneous retinal activity prior to vision. 
  • The Arp2/3 Complex Is Essential for Distinct Stages of Spine Synapse Maturation, Including Synapse Unsilencing. 
  • The HVC microcircuit: the synaptic basis for interactions between song motor and vocal plasticity pathways. 
  • The development of excitatory synapses in cultured spinal neurons. 
  • The implication of AMPA receptor in synaptic plasticity impairment and intellectual disability in fragile X syndrome. 
  • The role of N-methyl-D-aspartate receptor activation in homocysteine-induced death of retinal ganglion cells. 
  • The sequence of events that underlie quantal transmission at central glutamatergic synapses. 
  • TrkB activation by 7, 8-dihydroxyflavone increases synapse AMPA subunits and ameliorates spatial memory deficits in a mouse model of Alzheimer's disease. 
  • What determines the frequency of fast network oscillations with irregular neural discharges? I. Synaptic dynamics and excitation-inhibition balance. 
  • [Bradykinin modulates ion channel in inflammatory pain]. 
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  Keywords of People

  • Turner, Dennis Alan, Professor of Neurosurgery, Biomedical Engineering
  • Warner, David Samuel, Distinguished Professor of Anesthesiology, in the School of Medicine, Neurobiology