Receptors, Tumor Necrosis Factor
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Subject Areas on Research
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CRISPR-Based Epigenome Editing of Cytokine Receptors for the Promotion of Cell Survival and Tissue Deposition in Inflammatory Environments.
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A boy with fever and whorl keratopathy.
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A brief history of Wegener's granulomatosis: on limited, localized, and generalized forms of the disease: comment on the article by the Wegener's Granulomatosis Etanercept Trial Research Group.
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A crucial role for p80 TNF-R2 in amplifying p60 TNF-R1 apoptosis signals in T lymphocytes.
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A domain in TNF receptors that mediates ligand-independent receptor assembly and signaling.
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A lymphotoxin-IFN-beta axis essential for lymphocyte survival revealed during cytomegalovirus infection.
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A randomized comparative effectiveness study of oral triple therapy versus etanercept plus methotrexate in early aggressive rheumatoid arthritis: the treatment of Early Aggressive Rheumatoid Arthritis Trial.
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A role for tumor necrosis factor receptor-2 and receptor-interacting protein in programmed necrosis and antiviral responses.
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A serum proteomic approach to gauging the state of remission in Wegener's granulomatosis.
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A third distinct tumor necrosis factor receptor of orthopoxviruses.
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A20 protects mice from D-galactosamine/lipopolysaccharide acute toxic lethal hepatitis.
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Acute pancreatitis induces FasL gene expression and apoptosis in the liver.
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Age-Related Adverse Inflammatory and Metabolic Changes Begin Early in Adulthood.
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Allelic association of sequence variants in the herpes virus entry mediator-B gene (PVRL2) with the severity of multiple sclerosis.
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Alternate functions of viral regulators of cell death.
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Alveolar macrophage apoptosis and TNF-alpha, but not p53, expression correlate with murine response to bleomycin.
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Amelioration of inflammatory arthritis by targeting the pre-ligand assembly domain of tumor necrosis factor receptors.
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Apoptosis and NF-kappa B: the FADD connection.
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Assessment of health-related quality of life as an outcome measure in granulomatosis with polyangiitis (Wegener's).
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BLyS and APRIL in rheumatoid arthritis.
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Blockade of tissue factor: treatment for organ injury in established sepsis.
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CD30-dependent degradation of TRAF2: implications for negative regulation of TRAF signaling and the control of cell survival.
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CD4+CD45RBHi T cell transfer induced colitis in mice is accompanied by osteopenia which is treatable with recombinant human osteoprotegerin.
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Case reports of heart failure after therapy with a tumor necrosis factor antagonist.
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Cell density-dependent regulation of cell surface expression of two types of human tumor necrosis factor receptors and its effect on cellular response.
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Clinically inactive disease in a cohort of children with new-onset polyarticular juvenile idiopathic arthritis treated with early aggressive therapy: time to achievement, total duration, and predictors.
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Confirmation of administrative claims-identified opportunistic infections and other serious potential adverse events associated with tumor necrosis factor alpha antagonists and disease-modifying antirheumatic drugs.
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Constitutive proteasome-mediated turnover of Bfl-1/A1 and its processing in response to TNF receptor activation in FL5.12 pro-B cells convert it into a prodeath factor.
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Cowpox virus contains two copies of an early gene encoding a soluble secreted form of the type II TNF receptor.
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Cowpox virus encodes a fifth member of the tumor necrosis factor receptor family: a soluble, secreted CD30 homologue.
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Cowpox virus genome encodes a second soluble homologue of cellular TNF receptors, distinct from CrmB, that binds TNF but not LT alpha.
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Damage caused by Wegener's granulomatosis and its treatment: prospective data from the Wegener's Granulomatosis Etanercept Trial (WGET).
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Dendritic cells engineered to secrete anti-GITR antibodies are effective adjuvants to dendritic cell-based immunotherapy.
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Differences in susceptibility to tumor necrosis factor alpha-induced apoptosis among MCF-7 breast cancer cell variants.
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Differential effectiveness of etanercept and infliximab in the treatment of ocular inflammation.
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Direct-contact co-culture between smooth muscle and endothelial cells inhibits TNF-alpha-mediated endothelial cell activation.
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Discovery of high-affinity peptide binders to BLyS by phage display.
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Effects of etanercept therapy on fatigue and symptoms of depression in subjects treated for moderate to severe plaque psoriasis for up to 96 weeks.
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Effects of long-term etanercept treatment on growth in children with selected categories of juvenile idiopathic arthritis.
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Effects of the NIK aly mutation on NF-kappaB activation by the Epstein-Barr virus latent infection membrane protein, lymphotoxin beta receptor, and CD40.
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Endogenous tumor necrosis factor alpha (TNFalpha) requires TNF receptor type 2 to generate heat hyperalgesia in a mouse cancer model.
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Enhancing the immunostimulatory function of dendritic cells by transfection with mRNA encoding OX40 ligand.
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Etanercept (enbrel)-associated inflammatory eye disease: case report and review of the literature.
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Etanercept and clinical outcomes, fatigue, and depression in psoriasis: double-blind placebo-controlled randomised phase III trial.
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Etanercept plus standard therapy for Wegener's granulomatosis.
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Etanercept-induced lupus-like syndrome in a patient with rheumatoid arthritis.
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Expression of p14ARF, p15INK4b, p16INK4a, and DCR2 increases during prostate cancer progression.
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Extension study of participants from the trial of early aggressive therapy in juvenile idiopathic arthritis.
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Fas/FasL play a central role in pancreatitis-induced hepatocyte apoptosis.
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Flow cytometric analysis of fluorescence resonance energy transfer: a tool for high-throughput screening of molecular interactions in living cells.
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Fluorescence resonance energy transfer analysis of cell surface receptor interactions and signaling using spectral variants of the green fluorescent protein.
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Heart failure among younger rheumatoid arthritis and Crohn's patients exposed to TNF-alpha antagonists.
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Herpes zoster in immunocompromised patients: incidence, timing, and risk factors.
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Hodgkin's lymphoma and tumor necrosis factor inhibitors in juvenile idiopathic arthritis.
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IL-10 induces regulatory T cell apoptosis by up-regulation of the membrane form of TNF-alpha.
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Induction of apoptosis in vascular smooth muscle cells by mechanical stretch.
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Inflammation controls B lymphopoiesis by regulating chemokine CXCL12 expression.
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Inflammatory biomarkers in heart failure.
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Inhibitor of apoptosis proteins as intracellular signaling intermediates.
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Interferon regulatory factor-1-induced apoptosis mediated by a ligand-independent fas-associated death domain pathway in breast cancer cells.
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Juvenile idiopathic arthritis.
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Long-term safety and effectiveness of etanercept in children with selected categories of juvenile idiopathic arthritis.
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Mast cell TNF receptors regulate responses to Mycoplasma pneumoniae in surfactant protein A (SP-A)-/- mice.
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Moderate-intensity aerobic training program improves insulin sensitivity and inflammatory markers in a pilot study of morbidly obese minority teens.
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Monitoring molecular interactions in living cells using flow cytometric analysis of fluorescence resonance energy transfer.
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NF-kappaB RelA opposes epidermal proliferation driven by TNFR1 and JNK.
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Neutral effect on markers of heart failure, inflammation, endothelial activation and function, and vagal tone after high-dose HMG-CoA reductase inhibition in non-diabetic patients with non-ischemic cardiomyopathy and average low-density lipoprotein level.
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New treatments for rheumatoid arthritis.
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Nuclear factor-kappaB maintains TRAIL resistance in human pancreatic cancer cells.
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On the TRAIL from p53 to apoptosis?
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Ovarian reserve diminished by oral cyclophosphamide therapy for granulomatosis with polyangiitis (Wegener's).
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Overexpression of decoy receptor 3 in precancerous lesions and adenocarcinoma of the esophagus.
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Peripheral blood expression of nuclear factor-kappab-regulated genes is associated with rheumatoid arthritis disease activity and responds differentially to anti-tumor necrosis factor-alpha versus methotrexate.
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Phase 2 study of mapatumumab, a fully human agonistic monoclonal antibody which targets and activates the TRAIL receptor-1, in patients with advanced non-small cell lung cancer.
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Phosphorylation of tumor necrosis factor receptor 1 (p55) protects macrophages from silica-induced apoptosis.
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Phosphorylation-driven assembly of the RIP1-RIP3 complex regulates programmed necrosis and virus-induced inflammation.
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Photoreceptor synapses degenerate early in experimental choroidal neovascularization.
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Plasma matrix metalloproteinase and inhibitor profiles in patients with heart failure.
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Poxviral modifiers of cytokine responses to infection.
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Poxvirus tumor necrosis factor receptor (TNFR)-like T2 proteins contain a conserved preligand assembly domain that inhibits cellular TNFR1-induced cell death.
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Preligand assembly domain-mediated ligand-independent association between TRAIL receptor 4 (TR4) and TR2 regulates TRAIL-induced apoptosis.
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Progress in the treatment of rheumatoid arthritis.
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Proinflammatory cytokines increase in sepsis after anti-adhesion molecule therapy.
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Proliferative lupus nephritis and leukocytoclastic vasculitis during treatment with etanercept.
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Pulmonary toxicity of induction chemotherapy prior to standard or high-dose chemotherapy with autologous hematopoietic support.
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RANK, RANKL, OPG, and M-CSF expression in stromal cells during corneal wound healing.
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RNPS1 inhibits excessive tumor necrosis factor/tumor necrosis factor receptor signaling to support hematopoiesis in mice.
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Receptor-mediated monocytoid differentiation of human promyelocytic cells by tumor necrosis factor: synergistic actions with interferon-gamma and 1,25-dihydroxyvitamin D3.
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Recurrent fever and rash.
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Release and activity of anti-TNFalpha therapeutics from injectable chitosan preparations for local drug delivery.
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Repression of B7.2 on self-reactive B cells is essential to prevent proliferation and allow Fas-mediated deletion by CD4(+) T cells.
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Resolving TRPV1- and TNF-α-mediated spinal cord synaptic plasticity and inflammatory pain with neuroprotectin D1.
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Role of Fn14 in acute alcoholic steatohepatitis in mice.
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Severity of Plasma Leakage Is Associated With High Levels of Interferon γ-Inducible Protein 10, Hepatocyte Growth Factor, Matrix Metalloproteinase 2 (MMP-2), and MMP-9 During Dengue Virus Infection.
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Signaling by the TNF receptor superfamily and T cell homeostasis.
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Signaling pathway for apoptosis: a racetrack for life or death.
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Solid malignancies among etanercept-treated patients with granulomatosis with polyangiitis (Wegener's): long-term followup of a multicenter longitudinal cohort.
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Solid malignancies among patients in the Wegener's Granulomatosis Etanercept Trial.
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Spatiotemporal programming of a simple inflammatory process.
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Spinal injection of TNF-α-activated astrocytes produces persistent pain symptom mechanical allodynia by releasing monocyte chemoattractant protein-1.
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Studies on the interaction between TWEAK and the death receptor WSL-1/TRAMP (DR3).
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Sudden Cardiac Death in Patients With Ischemic Heart Failure Undergoing Coronary Artery Bypass Grafting: Results From the STICH Randomized Clinical Trial (Surgical Treatment for Ischemic Heart Failure).
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Suppression of antiproliferative effects of tumor necrosis factor by transfection of cells with human platelet-derived growth factor B/c-sis gene.
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TNF-α contributes to spinal cord synaptic plasticity and inflammatory pain: distinct role of TNF receptor subtypes 1 and 2.
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TWEAK/Fn14 signaling is required for liver regeneration after partial hepatectomy in mice.
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Targeted overexpression of G protein-coupled receptor kinase-2 in osteoblasts promotes bone loss.
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Targeting pro-inflammatory cytokines following joint injury: acute intra-articular inhibition of interleukin-1 following knee injury prevents post-traumatic arthritis.
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The control and execution of programmed cell death: an update.
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The pre-ligand binding assembly domain: a potential target of inhibition of tumour necrosis factor receptor function.
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The role of apoptosis in the development and function of T lymphocytes.
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Three is better than one: pre-ligand receptor assembly in the regulation of TNF receptor signaling.
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Tides of inflammation: impact of biologics.
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Transfection of cells with transforming growth factor-alpha leads to cellular resistance to the antiproliferative effects of tumor necrosis factor.
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Treatment of juvenile pityriasis rubra pilaris with etanercept.
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Trial of early aggressive therapy in polyarticular juvenile idiopathic arthritis.
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Tumor necrosis factor alpha (TNF alpha)-induced ICAM-1 surface expression in airway epithelial cells in vitro: possible signal transduction mechanisms.
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Tumor necrosis factor alpha and colitis-associated colon cancer.
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Tumor necrosis factor alpha as an autocrine and paracrine growth factor for ovarian cancer: monokine induction of tumor cell proliferation and tumor necrosis factor alpha expression.
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Tumor necrosis factor alpha promotes nuclear localization of cytokine-inducible CCAAT/enhancer binding protein isoforms in hepatocytes.
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Tumor necrosis factor blockers in rheumatoid arthritis.
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Tumor necrosis factor-alpha blockade: a novel therapy for rheumatic disease.
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Tumour necrosis factor receptor II polymorphism and juvenile idiopathic arthritis.
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Tumour necrosis factor-alpha blockade: a new era for effective management of rheumatoid arthritis.
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Unmasking the osteoinductive effects of a G-protein-coupled receptor (GPCR) kinase (GRK) inhibitor by treatment with PTH(1-34).
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pp60v-src kinase overexpression leads to cellular resistance to the antiproliferative effects of tumor necrosis factor.
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