Receptors, Calcitriol

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  Subject Areas on Research

  • Amyotrophic lateral sclerosis, lead, and genetic susceptibility: polymorphisms in the delta-aminolevulinic acid dehydratase and vitamin D receptor genes. 
  • Binding and metabolism of 1,25-dihydroxyvitamin D3 in cultured bovine parathyroid cells. 
  • Characterization of transcriptional activation and DNA-binding functions in the hinge region of the vitamin D receptor. 
  • Cloning and expression of full-length cDNA encoding human vitamin D receptor. 
  • Developmental exposure of zebrafish to vitamin D receptor acting drugs and environmental toxicants disrupts behavioral function. 
  • Differential effects of vitamin d receptor agonists on gene expression in neonatal rat cardiomyocytes. 
  • Evaluation of vitamin D biosynthesis and pathway target genes reveals UGT2A1/2 and EGFR polymorphisms associated with epithelial ovarian cancer in African American Women. 
  • Expression of human vitamin D receptor in Saccharomyces cerevisiae. Purification, properties, and generation of polyclonal antibodies. 
  • Expression of renal cell protein markers is dependent on initial mechanical culture conditions. 
  • Functional domains of the human vitamin D3 receptor regulate osteocalcin gene expression. 
  • Genetic Factors Associated with Absolute and Relative Plasma Concentrations of Calcitriol. 
  • Genetic variants and associations of 25-hydroxyvitamin D concentrations with major clinical outcomes. 
  • Genetic variants of the vitamin D receptor gene alter risk of cutaneous melanoma. 
  • Haplotype and genotypes of the VDR gene and cutaneous melanoma risk in non-Hispanic whites in Texas: a case-control study. 
  • Histone acetylation in keratinocytes enables control of the expression of cathelicidin and CD14 by 1,25-dihydroxyvitamin D3. 
  • Inhibition of 1,25-dihydroxyvitamin D3-dependent transcription by synthetic LXXLL peptide antagonists that target the activation domains of the vitamin D and retinoid X receptors. 
  • Injury enhances TLR2 function and antimicrobial peptide expression through a vitamin D-dependent mechanism. 
  • Maternal vitamin D receptor genetic variation contributes to infant birthweight among black mothers. 
  • Molecular biology of the vitamin D hormone. 
  • Paralogous VDRs in teleosts:transition of nuclear receptor function 
  • Paricalcitol versus cinacalcet plus low-dose vitamin D therapy for the treatment of secondary hyperparathyroidism in patients receiving haemodialysis: results of the IMPACT SHPT study. 
  • Polymorphisms of vitamin D receptor gene protect against the risk of head and neck cancer. 
  • Positive regulation of the vitamin D receptor by its cognate ligand in heterologous expression systems. 
  • RRR-alpha-vitamin E succinate potentiates the antitumor effect of calcitriol in prostate cancer without overt side effects. 
  • Reconstitution of the vitamin D-responsive osteocalcin transcription unit in Saccharomyces cerevisiae. 
  • Synthetic LXXLL peptide antagonize 1,25-dihydroxyvitamin D3-dependent transcription. 
  • The importance of the retinoid X receptor alpha in modulating inflammatory signaling in acute murine colitis. 
  • The vitamin D receptor gene as a determinant of survival in pancreatic cancer patients: Genomic analysis and experimental validation. 
  • The vitamin D receptor interacts preferentially with DRIP205-like LxxLL motifs. 
  • The vitamin D receptor: a primitive steroid receptor related to thyroid hormone receptor. 
  • Transcriptional control of intestinal cytochrome P-4503A by 1alpha,25-dihydroxy vitamin D3. 
  • Vitamin D Receptor Agonists for Patients Undergoing Hemodialysis. 
  • Vitamin D analogs differentially control antimicrobial peptide/"alarmin" expression in psoriasis. 
  • Vitamin D is Not Associated With Severity in NAFLD: Results of a Paired Clinical and Gene Expression Profile Analysis. 
  • Vitamin D receptor (VDR) polymorphisms and risk of ovarian cancer in Caucasian and African American women. 
  • Vitamin D receptor alleles do not correlate with bone mineral density in premenopausal Caucasian women from the southeastern United States. 
  • Vitamin D receptor and retinoid X receptor α status and vitamin D insufficiency in models of murine colitis. 
  • Vitamin D receptor interaction with specific DNA requires a nuclear protein and 1,25-dihydroxyvitamin D3. 
  • Vitamin D receptor polymorphisms and prostate cancer. 
  • Vitamin D receptors repress basal transcription and exert dominant negative activity on triiodothyronine-mediated transcriptional activity. 
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  Keywords of People

  • Berchuck, Andrew, James M. Ingram Distinguished Professor of Gynecologic Oncology, Obstetrics and Gynecology, Gynecologic Oncology
  • McDonnell, Donald Patrick, Glaxo-Wellcome Distinguished Professor of Molecular Cancer Biology, in the School of Medicine, Cell Biology