Herpesvirus 1, Human

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  Subject Areas on Research

  • A neuron-specific host microRNA targets herpes simplex virus-1 ICP0 expression and promotes latency. 
  • A selective inhibitor of eIF2alpha dephosphorylation protects cells from ER stress. 
  • Acute retinal necrosis following epidural steroid injections. 
  • Acyclovir or Aβ42 peptides attenuate HSV-1-induced miRNA-146a levels in human primary brain cells. 
  • Analysis of human alphaherpesvirus microRNA expression in latently infected human trigeminal ganglia. 
  • Analysis of regulatory CD8 T cells in Qa-1-deficient mice. 
  • Antibody to HSV gD peptide induced by vaccination does not protect against HSV-2 infection in HSV-2 seronegative women. 
  • Efficacy of Talimogene Laherparepvec (T-VEC) Therapy in Patients with In-Transit Melanoma Metastasis Decreases with Increasing Lesion Size. 
  • Evaluation of HLA polymorphisms in relation to schizophrenia risk and infectious exposure. 
  • Evolution and diversity in human herpes simplex virus genomes. 
  • Exploiting the exploiter: a viral inhibitor stabilizes TAP for cryo-EM. 
  • Gene Editing: A New Tool for Viral Disease. 
  • HSV-1 amplicon vector-mediated expression of ATM cDNA and correction of the ataxia-telangiectasia cellular phenotype. 
  • Hemorrhagic Herpes Simplex Virus Type 1 Nephritis: An Unusual Cause of Acute Allograft Dysfunction. 
  • Herpes Simplex Virus 1 Infection of Tree Shrews Differs from That of Mice in the Severity of Acute Infection and Viral Transcription in the Peripheral Nervous System. 
  • Herpes simplex virus proteins ICP27 and UL47 associate with polyadenylate-binding protein and control its subcellular distribution. 
  • Herpetic keratitis in experimental vitamin A deficiency. 
  • ICP34.5-dependent and -independent activities of salubrinal in herpes simplex virus-1 infected cells. 
  • Immunotherapy Gone Viral: Bortezomib and oHSV Enhance Antitumor NK-Cell Activity. 
  • Induction in vitro of primary cytotoxic T-lymphocyte responses with DNA encoding herpes simplex virus proteins. 
  • Infectious pathogen detection arrays: viral detection in cell lines and postmortem brain tissue. 
  • Injectable Therapies for Regional Melanoma. 
  • Knockin mice expressing a chimeric p53 protein reveal mechanistic differences in how p53 triggers apoptosis and senescence. 
  • MLKL Requires the Inositol Phosphate Code to Execute Necroptosis. 
  • MicroRNAs expressed by herpes simplex virus 1 during latent infection regulate viral mRNAs. 
  • Modulation of murine herpes simplex virus type 1 retinitis in the uninoculated eye by CD4+ T lymphocytes. 
  • Mutational inactivation of herpes simplex virus 1 microRNAs identifies viral mRNA targets and reveals phenotypic effects in culture. 
  • Natural history of neonatal herpes simplex virus infections in the acyclovir era. 
  • Nelfinavir inhibits maturation and export of herpes simplex virus 1. 
  • Neonatal herpetic hepatitis. 
  • OPTN is a host intrinsic restriction factor against neuroinvasive HSV-1 infection. 
  • Reduced expression of brain-enriched microRNAs in glioblastomas permits targeted regulation of a cell death gene. 
  • Retreatment with talimogene laherparepvec for advanced melanoma. 
  • Role of MCP-1 and IL-8 in viral anterior uveitis, and contractility and fibrogenic activity of trabecular meshwork cells. 
  • Role of macrophages in restricting herpes simplex virus type 1 growth after ocular infection. 
  • Structure of herpes simplex virus glycoprotein D bound to the human receptor nectin-1. 
  • Sudden Unilateral Decrease in Vision in a Healthy Middle-aged Man. 
  • Virology. New trick from an old foe. 
  • Viruses in the treatment of brain tumors. 
  • [Analgesic effect of intrathecal injection of Herpes simplex virus type I amplicon vector-mediated human preproenkephalin gene on chronic neuropathic pain: experiment with rats]. 
  • [Experimental studies on human lung cancer gene-therapy with HSV-TK/GCV system]. 
  • [Intrathecal administration of HSV-I amplicon vector-mediated HPPE gene therapy of nocicepion in rats with formalin pain]. 
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  Keywords of People

  • Luftig, Micah Alan, Associate Professor of Molecular Genetics and Microbiology, Immunology
  • Shinohara, Mari L., Associate Professor of Immunology, Immunology