Electroporation
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Subject Areas on Research
- A single molecule detection method for understanding mechanisms of electric field-mediated interstitial transport of genes.
- A synthetic mimic of the secretory granule for drug delivery.
- ASO Author Reflections: Irreversible Electroporation for Locally Advanced Pancreatic Cancer.
- Ablation of perivascular hepatic malignant tumors with irreversible electroporation.
- Ablation of the locally advanced pancreatic cancer: An introduction and brief summary of techniques.
- Activated B cells modified by electroporation of multiple mRNAs encoding immune stimulatory molecules are comparable to mature dendritic cells in inducing in vitro antigen-specific T-cell responses.
- Activating function of needle electrodes in anisotropic tissue
- Activation of the NLRP3 inflammasome by intracellular poly I:C.
- Asymmetrical electrically induced injury of rabbit ventricular myocytes.
- Cellular and humoral responses to an HIV DNA prime by electroporation boosted with recombinant vesicular stomatitis virus expressing HIV subtype C Env in a randomized controlled clinical trial.
- Comparison of intradermal and intramuscular delivery followed by in vivo electroporation of SIV Env DNA in macaques.
- Correction of dystrophin expression in cells from Duchenne muscular dystrophy patients through genomic excision of exon 51 by zinc finger nucleases.
- Current Progress in Electrotransfection as a Nonviral Method for Gene Delivery.
- DNA and protein co-immunization improves the magnitude and longevity of humoral immune responses in macaques.
- DNA vaccination by intradermal electroporation induces long-lasting immune responses in rhesus macaques.
- Delivery of Synthetic mRNA Encoding FOXP3 Antigen into Dendritic Cells for Inflammatory Breast Cancer Immunotherapy.
- Dendritic Cell-Activating Magnetic Nanoparticles Enable Early Prediction of Antitumor Response with Magnetic Resonance Imaging.
- Differential effects of toll-like receptor stimulation on mRNA-driven myogenic conversion of human and mouse fibroblasts.
- Effect of plasmid DNA vaccine design and in vivo electroporation on the resulting vaccine-specific immune responses in rhesus macaques.
- Effective tumor therapy with plasmid-encoded cytokines combined with in vivo electroporation.
- Effects of electroporation on the transmembrane potential distribution in a two-dimensional bidomain model of cardiac tissue.
- Effects of electroporation on transmembrane potential induced by defibrillation shocks.
- Electric field of a six-needle array electrode used in drug and DNA delivery in vivo: analytical versus numerical solution.
- Electric fields around and within single cells during electroporation-a model study.
- Electric fields in tumors exposed to external voltage sources: implication for electric field-mediated drug and gene delivery.
- Electrical energy required to form large conducting pores.
- Electromobility of plasmid DNA in tumor tissues during electric field-mediated gene delivery.
- Electroporation and shock-induced transmembrane potential in a cardiac fiber during defibrillation strength shocks.
- Enhanced dendritic cell antigen presentation in RNA-based immunotherapy.
- Enhancement of electric field-mediated gene delivery through pretreatment of tumors with a hyperosmotic mannitol solution.
- Enhancement of topical 5-aminolaevulinic acid delivery by erbium:YAG laser and microdermabrasion: a comparison with iontophoresis and electroporation.
- Experimental evidence of improved transthoracic defibrillation with electroporation-enhancing pulses.
- Field distribution and DNA transport in solid tumors during electric field-mediated gene delivery.
- Gene delivery systems in surgery.
- Gene disruption by biolistic transformation in serotype D strains of Cryptococcus neoformans.
- Gene silencing using RNA interference in embryonic stem cells.
- Generation and comparison of CRISPR-Cas9 and Cre-mediated genetically engineered mouse models of sarcoma.
- IL-12 DNA as molecular vaccine adjuvant increases the cytotoxic T cell responses and breadth of humoral immune responses in SIV DNA vaccinated macaques.
- In vivo electroporation and non-protein based screening assays to identify antibodies against native protein conformations.
- Increased vascular smooth muscle contractility in TRPC6-/- mice.
- Insulin-triggered repositioning of munc18c on syntaxin-4 in GLUT4 signalling.
- Intratumoral Plasmid IL12 Expands CD8+ T Cells and Induces a CXCR3 Gene Signature in Triple-negative Breast Tumors that Sensitizes Patients to Anti-PD-1 Therapy.
- Intravital imaging of mouse embryos.
- Invited commentary.
- Involvement of a Rac1-Dependent Macropinocytosis Pathway in Plasmid DNA Delivery by Electrotransfection.
- Involvement of the S-layer proteins Hpi and SlpA in the maintenance of cell envelope integrity in Deinococcus radiodurans R1.
- Irreversible Electroporation (IRE) Combined With Chemotherapy Increases Survival in Locally Advanced Pancreatic Cancer (LAPC).
- Irreversible Electroporation for the Treatment of Small Renal Masses: 5-Year Outcomes.
- Irreversible electroporation (Nanoknife® treatment) in the field of hepatobiliary surgery: Current status and future perspectives.
- Irreversible electroporation in a case of pancreatic leiomyosarcoma: a novel weapon versus a rare malignancy?
- Kinetics of release of serotonin from isolated secretory granules. I. Amperometric detection of serotonin from electroporated granules.
- Live imaging of mitosis in the developing mouse embryonic cortex.
- Manipulation of OCT4 levels in human embryonic stem cells results in induction of differential cell types.
- Measuring Hepatitis C Virus Envelopment by Using a Proteinase K Protection Assay.
- Mechanistic analysis of electroporation-induced cellular uptake of macromolecules.
- Membrane attachment is key to protecting transducin GTPase-activating complex from intracellular proteolysis in photoreceptors.
- Misexpression of ptf1a in cortical pyramidal cells in vivo promotes an inhibitory peptidergic identity.
- Model of creation and evolution of stable electropores for DNA delivery.
- Modeling electroporation in a single cell.
- Modeling electroporation in a single cell. I. Effects Of field strength and rest potential.
- Neocortical disynaptic inhibition requires somatodendritic integration in interneurons.
- Neurod6 expression defines new retinal amacrine cell subtypes and regulates their fate.
- Prime-boost regimens with adjuvanted synthetic long peptides elicit T cells and antibodies to conserved regions of HIV-1 in macaques.
- Progenitor Hyperpolarization Regulates the Sequential Generation of Neuronal Subtypes in the Developing Neocortex.
- Progressive Rod-Cone Degeneration (PRCD) Protein Requires N-Terminal S-Acylation and Rhodopsin Binding for Photoreceptor Outer Segment Localization and Maintaining Intracellular Stability.
- Real-World Comparative Safety and Effectiveness of Irreversible Electroporation and High-Intensity Focused Ultrasound for Prostate Cancer Ablation.
- Redirecting Vesicular Transport to Improve Nonviral Delivery of Molecular Cargo.
- Reduced aspartate release from rat hippocampal synaptosomes loaded with Clostridial toxin light chain by electroporation: evidence for an exocytotic mechanism.
- Redundancy renders the glycoprotein 96 receptor scavenger receptor A dispensable for cross priming in vivo.
- Regulation of blood pressure by the type 1A angiotensin II receptor gene.
- Rem2 is an activity-dependent negative regulator of dendritic complexity in vivo.
- SUN1/2 and Syne/Nesprin-1/2 complexes connect centrosome to the nucleus during neurogenesis and neuronal migration in mice.
- Scalable Device for Automated Microbial Electroporation in a Digital Microfluidic Platform.
- Selective modification of antigen-specific T cells by RNA electroporation.
- Singular perturbation analysis of the pore creation transient.
- Systematic Review of Surgical and Percutaneous Irreversible Electroporation in the Treatment of Locally Advanced Pancreatic Cancer.
- The efficacy and safety of the open approach irreversible electroporation in the treatment of pancreatic cancer: A systematic review.
- The forkhead genes, Foxc1 and Foxc2, regulate paraxial versus intermediate mesoderm cell fate.
- Theoretical modeling of the effects of shock duration, frequency, and strength on the degree of electroporation.
- Transfecting Human Monocytes with RNA.
- Utilizing In Vivo Postnatal Electroporation to Study Cerebellar Granule Neuron Morphology and Synapse Development.
- Whole blood cells loaded with messenger RNA as an anti-tumor vaccine.
- siRNA inhibition of aspartyl-asparaginyl β-hydroxylase expression impairs cell motility, Notch signaling, and fetal growth.
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Keywords of People
- Neu, Wanda Krassowska, Professor Emeritus of Biomedical Engineering, Biomedical Engineering
- Sampson, John Howard, Robert H., M.D. and Gloria Wilkins Professor of Neurosurgery, in the School of Medicine, Biomedical Engineering
- Silver, Debra Lynn, Associate Professor of Molecular Genetics and Microbiology, Duke Science & Society