Leishmania major

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  Subject Areas on Research

  • A targeted and adjuvanted nanocarrier lowers the effective dose of liposomal amphotericin B and enhances adaptive immunity in murine cutaneous leishmaniasis. 
  • Biochemical characterization of Leishmania major aquaglyceroporin LmAQP1: possible role in volume regulation and osmotaxis. 
  • Compartmental responses to acute osmotic stress in Leishmania major result in rapid loss of Na+ and Cl-. 
  • Engagement of NKG2D on bystander memory CD8 T cells promotes increased immunopathology following Leishmania major infection. 
  • Lymphocytic Choriomeningitis Virus Expands a Population of NKG2D+CD8+ T Cells That Exacerbates Disease in Mice Coinfected with Leishmania major. 
  • Pathogen Evasion of Chemokine Response Through Suppression of CXCL10. 
  • The Wnt Antagonist Dickkopf-1 Promotes Pathological Type 2 Cell-Mediated Inflammation. 
  • Variation in Leishmania chemokine suppression driven by diversification of the GP63 virulence factor.