Neuroendocrine Tumors

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  Subject Areas on Research

  • 68Ga-DOTATATE: Significance of Uptake in the Tail of the Pancreas in Patients Without Lesions. 
  • A DLL3-targeted antibody-drug conjugate eradicates high-grade pulmonary neuroendocrine tumor-initiating cells in vivo. 
  • A case report on metastatic ileal neuroendocrine neoplasm to the breast masquerading as primary breast cancer: A diagnostic challenge and management dilemma. 
  • A literature-based treatment algorithm for low-grade neuroendocrine liver metastases. 
  • A pilot genome-wide association study shows genomic variants enriched in the non-tumor cells of patients with well-differentiated neuroendocrine tumors of the ileum. 
  • A precision oncology approach to the pharmacological targeting of mechanistic dependencies in neuroendocrine tumors. 
  • A single institution's 26-year experience with nonfunctional pancreatic neuroendocrine tumors: a validation of current staging systems and a new prognostic nomogram. 
  • ACR Practice Parameter for the Performance of Gallium-68 DOTATATE PET/CT for Neuroendocrine Tumors. 
  • ACR-ACNM-ASTRO-SNMMI Practice Parameter for Lutetium-177 (Lu-177) DOTATATE Therapy. 
  • ACR-ACNM-ASTRO-SNMMI Practice Parameter for Lutetium-177 (Lu-177) DOTATATE Therapy. 
  • ASO Author Reflection: Postoperative Chemotherapy for Nonmetastatic, Poorly Differentiated Gastroenteropancreatic Neuroendocrine Carcinomas. 
  • Androgen-deprivation therapy-induced aggressive prostate cancer with neuroendocrine differentiation. 
  • Attenuation of the retinoblastoma pathway in pancreatic neuroendocrine tumors due to increased cdk4/cdk6. 
  • Cadherin 17 is frequently expressed by 'sclerosing variant' pancreatic neuroendocrine tumour. 
  • Calcitonin driven v-Ha-ras induces multilineage pulmonary epithelial hyperplasias and neoplasms. 
  • Choroidal metastatasis from a neuroendocrine tumor masquerading as choroidal melanoma. 
  • Comment on "Resection of the Primary Gastrointestinal Neuroendocrine Tumor Improves Survival With or Without Liver Treatment". 
  • Competing Mortality in Patients With Neuroendocrine Tumors. 
  • DAXX/ATRX, MEN1, and mTOR pathway genes are frequently altered in pancreatic neuroendocrine tumors. 
  • Differential Diagnosis of Diarrhea in Patients With Neuroendocrine Tumors. 
  • Diffuse Idiopathic Pulmonary Neuroendocrine Cell Hyperplasia: Imaging and Clinical Features of a Frequently Delayed Diagnosis. 
  • Dual Somatostatin Receptor/FDG PET/CT Imaging in Metastatic Neuroendocrine Tumours: Proposal for a Novel Grading Scheme with Prognostic Significance. 
  • EGFR-upregulated LIFR promotes SUCLG2-dependent castration resistance and neuroendocrine differentiation of prostate cancer. 
  • Early onset pancreatic malignancies: Clinical characteristics and survival associations. 
  • Efficacy and Safety of Sunitinib in Patients with Well-Differentiated Pancreatic Neuroendocrine Tumours. 
  • Embryonic lethal abnormal visual RNA-binding proteins involved in growth, differentiation, and posttranscriptional gene expression. 
  • Evaluation of the risk factors associated with rectal neuroendocrine tumors: a big data analytic study from a health screening center. 
  • Expression of CD24, a Stem Cell Marker, in Pancreatic and Small Intestinal Neuroendocrine Tumors. 
  • Frequent BRAF mutations suggest a novel oncogenic driver in colonic neuroendocrine carcinoma. 
  • Ga-68 DOTATATE PET/CT and F-18 FDG PET/CT in the evaluation of low and intermediate versus high-grade neuroendocrine tumors. 
  • Gastric neuroendocrine tumours from long-term proton pump inhibitor users are indolent tumours with good prognosis. 
  • Grading of well-differentiated pancreatic neuroendocrine tumors is improved by the inclusion of both Ki67 proliferative index and mitotic rate. 
  • Hepatic micrometastases are associated with poor prognosis in patients with liver metastases from neuroendocrine tumors of the digestive tract. 
  • Immunohistochemical characterization of neuroendocrine cells in prostate cancer. 
  • Impact of Peritoneal Metastasis on Survival of Patients With Small Intestinal Neuroendocrine Tumor. 
  • Impact of Point-Spread Function Reconstruction on 68Ga-DOTATATE PET/CT Quantitative Imaging Parameters. 
  • Impact of extent of surgery on survival in patients with small nonfunctional pancreatic neuroendocrine tumors in the United States. 
  • Impact of liver tumour burden, alkaline phosphatase elevation, and target lesion size on treatment outcomes with 177Lu-Dotatate: an analysis of the NETTER-1 study. 
  • In liver metastases from small intestinal neuroendocrine tumors, SSTR2A expression is heterogeneous. 
  • Insights into Novel Prognostic and Possible Predictive Biomarkers of Lung Neuroendocrine Tumors. 
  • Intensity-modulated radiation therapy for anal malignancies: a preliminary toxicity and disease outcomes analysis. 
  • Is Resection of Primary Midgut Neuroendocrine Tumors in Patients with Unresectable Metastatic Liver Disease Justified? A Systematic Review and Meta-Analysis. 
  • Is There a Role for Surgery in Patients with Neuroendocrine Tumors of the Esophagus? A Contemporary View from the NCDB. 
  • LIN28B promotes the development of neuroendocrine prostate cancer. 
  • Limited role of Chromogranin A as clinical biomarker for pancreatic neuroendocrine tumors. 
  • Lipid-rich variant of a pancreatic endocrine neoplasm in an endoscopic ultrasound-guided fine needle aspiration biopsy. 
  • Liver metastases from pituitary carcinomas mimicking visceral well-differentiated neuroendocrine tumors: a series of four cases. 
  • Liver metastases of small intestine neuroendocrine tumors: Ki-67 heterogeneity and World Health Organization grade discordance with primary tumors. 
  • Liver transplantation in patients with liver metastases from neuroendocrine tumors: A systematic review. 
  • MYC Drives Temporal Evolution of Small Cell Lung Cancer Subtypes by Reprogramming Neuroendocrine Fate. 
  • Management of advanced neuroendocrine tumors with hepatic metastasis. 
  • Mesenteric Tumor Deposits in Midgut Small Intestinal Neuroendocrine Tumors Are a Stronger Indicator Than Lymph Node Metastasis for Liver Metastasis and Poor Prognosis. 
  • Mesenteric tumour deposits arising from small-intestine neuroendocrine tumours are frequently associated with fibrosis and IgG4-expressing plasma cells. 
  • Molecular Imaging and Therapy for Neuroendocrine Tumors. 
  • Molecular Imaging in the Head and Neck: Diagnosis and Therapy. 
  • Morphologic Spectrum of Neuroendocrine Tumors of the Prostate: An Updated Review. 
  • Multi-institutional Development and External Validation of a Nomogram to Predict Recurrence After Curative Resection of Pancreatic Neuroendocrine Tumors. 
  • N-Myc Drives Neuroendocrine Prostate Cancer Initiated from Human Prostate Epithelial Cells. 
  • NCCN Guidelines Insights: Neuroendocrine and Adrenal Tumors, Version 2.2018. 
  • NCCN practice guidelines for occult primary tumors. National Comprehensive Cancer Network. 
  • Neuroendocrine Neoplasms of the Appendix: A Review of the Literature. 
  • Neuroendocrine Tumor Diagnosis and Management: 68Ga-DOTATATE PET/CT. 
  • Neuroendocrine and Adrenal Tumors, Version 2.2021, NCCN Clinical Practice Guidelines in Oncology. 
  • Neuroendocrine differentiation is an independent prognostic factor in chemotherapy-treated nonsmall cell lung carcinoma. 
  • Neuroendocrine neoplasms of the GI tract: the role of cytotoxic chemotherapy. 
  • Neuroendocrine tumors of the gastrointestinal tract and the role of cytotoxic chemotherapy. 
  • Neuroendocrine tumors, version 1.2015. 
  • Number, not size, of mesenteric tumor deposits affects prognosis of small intestinal well-differentiated neuroendocrine tumors. 
  • O6-Methylguanine DNA Methyltransferase Status Does Not Predict Response or Resistance to Alkylating Agents in Well-Differentiated Pancreatic Neuroendocrine Tumors. 
  • Objective radiological disease control with sandostatin monotherapy in metastatic neuroendocrine tumours. 
  • Observation versus Resection for Small Asymptomatic Pancreatic Neuroendocrine Tumors: A Matched Case-Control Study. 
  • Outcomes of Lymph Node Dissection for Non-metastatic Pancreatic Neuroendocrine Tumors: A Propensity Score-Weighted Analysis of the National Cancer Database. 
  • Overexpression of SOX11 and TFE3 in Solid-Pseudopapillary Neoplasms of the Pancreas. 
  • PET-Computed Tomography and Precision Medicine in Pancreatic Adenocarcinoma and Pancreatic Neuroendocrine Tumors. 
  • Pan-cancer Convergence to a Small-Cell Neuroendocrine Phenotype that Shares Susceptibilities with Hematological Malignancies. 
  • Pancreatic FNA in 1000 cases: a comparison of imaging modalities. 
  • Pancreatic Neuroendocrine Tumors. 
  • Pancreatic neuroendocrine tumor with cystlike changes: evaluation with MDCT. 
  • Pancreatic neuroendocrine tumors with involved surgical margins: prognostic factors and the role of adjuvant radiotherapy. 
  • Pancreatic neuroendocrine tumors: pathologic and molecular characteristics. 
  • Pathologic grade and tumor size are associated with recurrence-free survival in patients with duodenal neuroendocrine tumors. 
  • Patient-reported experience of the impact and burden of neuroendocrine tumors: Oceania patient results from a large global survey. 
  • Platinum sensitivity in metastatic prostate cancer: does histology matter? 
  • Potential therapeutic effect of epigenetic therapy on treatment-induced neuroendocrine prostate cancer. 
  • Predicting aggressive behavior in nonfunctioning pancreatic neuroendocrine tumors. 
  • Predictors of Survival in 211 Patients with Stage IV Pulmonary and Gastroenteropancreatic MIBG-Positive Neuroendocrine Tumors Treated with 131I-MIBG. 
  • Primary Breast Neuroendocrine Tumor. 
  • Proceed with caution: liver transplantation for metastatic neuroendocrine tumors. 
  • RNA Splicing of the BHC80 Gene Contributes to Neuroendocrine Prostate Cancer Progression. 
  • Resected pancreatic neuroendocrine tumors: patterns of failure and disease-related outcomes with or without radiotherapy. 
  • Resolution of hepatic encephalopathy following hepatic artery embolization in a patient with well-differentiated neuroendocrine tumor metastatic to the liver. 
  • SATB2 protein expression by immunohistochemistry is a sensitive and specific marker of appendiceal and rectosigmoid well differentiated neuroendocrine tumours. 
  • SOX9: a useful marker for pancreatic ductal lineage of pancreatic neoplasms. 
  • Safety and Efficacy of 68Ga-DOTATATE PET/CT for Diagnosis, Staging, and Treatment Management of Neuroendocrine Tumors. 
  • Section Editor's Notebook: ⁶⁸ Ga- and ¹⁷⁷ Lu-DOTATATE Theragnostics-Personalized Care and Improving Patient Outcomes. 
  • Selective expression of CD44, a putative prostate cancer stem cell marker, in neuroendocrine tumor cells of human prostate cancer. 
  • Serotonin expression in pancreatic neuroendocrine tumors correlates with a trabecular histologic pattern and large duct involvement. 
  • Should Ki67 immunohistochemistry be performed on all lesions in multifocal small intestinal neuroendocrine tumours? 
  • Should mesenteric tumor deposits be included in staging of well-differentiated small intestine neuroendocrine tumors? 
  • Small serotonin-producing neuroendocrine tumor of the pancreas associated with pancreatic duct obstruction. 
  • Synchronous resection of primary and liver metastases for neuroendocrine tumors. 
  • Targeting cellular heterogeneity with CXCR2 blockade for the treatment of therapy-resistant prostate cancer. 
  • The Chicago Consensus on Peritoneal Surface Malignancies: Management of Neuroendocrine Tumors. 
  • The Chicago Consensus on peritoneal surface malignancies: Management of neuroendocrine tumors. 
  • The Role of Surgery for Pancreatic Neuroendocrine Tumors. 
  • The high-grade (WHO G3) pancreatic neuroendocrine tumor category is morphologically and biologically heterogenous and includes both well differentiated and poorly differentiated neoplasms. 
  • The role of endoscopy in the evaluation and management of patients with solid pancreatic neoplasia. 
  • Therapy With ¹⁷⁷ Lu-DOTATATE: Clinical Implementation and Impact on Care of Patients With Neuroendocrine Tumors. 
  • Treatment Response and Outcomes of Grade 3 Pancreatic Neuroendocrine Neoplasms Based on Morphology: Well Differentiated Versus Poorly Differentiated. 
  • Two Extraordinary Sellar Neuronal Tumors: Literature Review and Comparison of Clinicopathologic Features. 
  • Update on Surgical Management of Small Bowel Neuroendocrine Tumors. 
  • Use of Everolimus After Multivisceral Transplantation: A Report of Two Cases. 
  • Well-Differentiated Neuroendocrine Tumors with a Morphologically Apparent High-Grade Component: A Pathway Distinct from Poorly Differentiated Neuroendocrine Carcinomas. 
  • Whole-Genome and Transcriptional Analysis of Treatment-Emergent Small-Cell Neuroendocrine Prostate Cancer Demonstrates Intraclass Heterogeneity. 
  • mRNA profiling of a well-differentiated G1 pancreatic NET correlates with immunohistochemistry profile: a case report. 
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  Keywords of People

  • Yoo, Sua, Associate Professor of Radiation Oncology, Radiation Oncology