Neurotransmitter Agents

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  Subject Areas on Research

  • 5-HT2C Agonists Modulate Schizophrenia-Like Behaviors in Mice. 
  • A Specialized Neural Circuit Gates Social Vocalizations in the Mouse. 
  • A historical perspective on the discovery of adenyl purines. 
  • Acquiring local field potential information from amperometric neurochemical recordings. 
  • Alterations in neurotransmitter activity after acute and chronic ethanol treatment: studies of transmitter interactions. 
  • Altered expression of genes involved in GABAergic transmission and neuromodulation of granule cell activity in the cerebellum of schizophrenia patients. 
  • An exploratory pilot investigation of neurosteroids and self-reported pain in female Iraq/Afghanistan-era Veterans. 
  • Animal models of the mechanisms of action of repetitive transcranial magnetic stimulation (RTMS): comparisons with electroconvulsive shock (ECS). 
  • Are neuromodulating medications effective for the treatment of chronic neurogenic cough? 
  • Aspartate and glutamate as possible transmitters of excitatory hippocampal afferents. 
  • Autocrine and paracrine mechanisms in the pathophysiology of heart failure. 
  • Autocrine-paracrine mechanisms of vascular myocytes in systemic hypertension. 
  • BDE99 (2,2',4,4',5-pentabromodiphenyl ether) suppresses differentiation into neurotransmitter phenotypes in PC12 cells. 
  • Baroreceptor function in congestive heart failure: effect on neurohumoral activation and regional vascular resistance. 
  • Biochemical approaches to studying neurotoxicity. 
  • Biochemical mechanisms of developmental neurotoxicity of methylmercury. 
  • Biological characterization of social phobia. 
  • Biosynthetically intriguing chlorinated lipophilic metabolites from geographically distant tropical marine cyanobacteria. 
  • Block and modulation of cardiac Na+ channels by antiarrhythmic drugs, neurotransmitters and hormones. 
  • Bombesin inhibits alveolarization and promotes pulmonary fibrosis in newborn mice. 
  • Botulinum neurotoxin as a therapeutic modality in orthopaedic surgery: more than twenty years of experience. 
  • Brain neurotransmitter turnover rates during rat intravenous cocaine self-administration. 
  • Brief embryonic strychnine exposure in zebrafish causes long-term adult behavioral impairment with indications of embryonic synaptic changes. 
  • British Association for Psychopharmacology consensus statement on evidence-based treatment of insomnia, parasomnias and circadian rhythm disorders. 
  • CNS inflammation and bone marrow neuropathy in type 1 diabetes. 
  • Cellular and Synaptic Properties of Local Inhibitory Circuits. 
  • Cerebrospinal Fluid Pterins, Pterin-Dependent Neurotransmitters, and Mortality in Pediatric Cerebral Malaria. 
  • Characterization of putative amino acid transmitter release from slices of rat dentate gyrus. 
  • Circumstances influencing Otto Loewi's discovery of chemical transmission in the nervous system. 
  • Colocalization of excitatory and inhibitory neurotransmitter markers in striatal projection neurons in the rat. 
  • Comparative developmental neurotoxicity of organophosphates in vivo: transcriptional responses of pathways for brain cell development, cell signaling, cytotoxicity and neurotransmitter systems. 
  • Comparing pharmacological treatments for cocaine dependence: Incorporation of methods for enhancing generalizability in meta-analytic studies. 
  • Comparison of responses to pituitary adenylate cyclase activating peptides 38 and 27 in the pulmonary vascular bed of the cat. 
  • Complex neuronal systems: approach to development of new strategies in the treatment of epilepsy. 
  • Comprehensive processing, display and analysis for in vivo MR spectroscopic imaging. 
  • Contributions of neuroendocrine and local autocrine-paracrine mechanisms to the pathophysiology and pharmacology of congestive heart failure. 
  • DHEA enhances emotion regulation neurocircuits and modulates memory for emotional stimuli. 
  • DHEA metabolism to the neurosteroid androsterone: a possible mechanism of DHEA's antidepressant action. 
  • Depression by calcium of spontaneous transmitter release at the mammalian neuromuscular junction. 
  • Development and neural bases of face recognition in autism. 
  • Development of polyamine and biogenic amine systems in brains and hearts of neonatal rats given dexamethasone: role of biochemical alterations in cellular maturation for producing deficits in ontogeny of neurotransmitter levels, uptake, storage and turnover. 
  • Developmental cholinotoxicants: nicotine and chlorpyrifos. 
  • Different presynaptic roles of synapsins at excitatory and inhibitory synapses. 
  • Direct identification and characterisation of beta-adrenergic receptors in rat brain. 
  • Disrupting nicotine reinforcement: from cigarette to brain. 
  • Dopaminergic modulation of retinal processing from starlight to sunlight. 
  • Early pharmacological treatment of autism: a rationale for developmental treatment. 
  • Easing the burden of social anxiety disorder. 
  • Effect of helium and heliox on glutamate decarboxylase activity. 
  • Effect of oxygen at high pressure on spontaneous transmitter release. 
  • Effects of barbiturates on inhibitory and excitatory responses to applied neurotransmitters in Aplysia. 
  • Effects of neonatal mercuric chloride administration on growth and biochemical development of neuronal and non-neuronal tissues in the rat: comparison with methylmercury. 
  • Effects of perinatal exposure to methadone on development of neurotransmission: biochemical bases for behavioral alterations. 
  • Effects of vagal neuromodulation on feeding behavior. 
  • Emerging drugs for attention-deficit/hyperactivity disorder. 
  • Excitatory amino acid neurotoxins: selectivity, specificity, and mechanisms of action. Based on an NRP one-day conference held June 30, 1980. 
  • Exposure to methylmercury in utero: effects on biochemical development of catecholamine neurotransmitter systems. 
  • Expression of pituitary adenylate cyclase-activating polypeptide in dorsal root ganglia following axotomy: time course and coexistence. 
  • Fetal nicotine or cocaine exposure: which one is worse? 
  • GABAergic signaling beyond synapses: an emerging target for cancer therapy. 
  • Glutamate as transmitter of hippocampal perforant path. 
  • Hepatic fibrogenesis requires sympathetic neurotransmitters. 
  • Impaired development of central and peripheral catecholamine neurotransmitter systems in preweanling rats treated with alpha-difluoromethylornithine, a specific irreversible inhibitor of ornithine decarboxylase. 
  • Influence of common drugs and related factors on stroke outcome. 
  • Inhibitors of metalloendoprotease activity prevent K+-stimulated neurotransmitter release from the retina of Xenopus laevis. 
  • Intracerebroventricular infusion of bombesin modulates GIP secretion in conscious dogs. 
  • Ion-exchange gel regulates neurotransmitter release through the exocytotic fusion pore. 
  • Is thrombosis a contributor to heart failure pathophysiology? Possible mechanisms, therapeutic opportunities, and clinical investigation challenges. 
  • Kindling model of epilepsy. 
  • Lysophosphatidic acid stimulates neurotransmitter-like conductance changes that precede GABA and L-glutamate in early, presumptive cortical neuroblasts. 
  • Maturation of neuromodulatory effect of substance P in rabbit airways. 
  • Membrane currents underlying bursting pacemaker activity and spike frequency adaptation in invertebrates. 
  • Mode of action: disruption of brain cell replication, second messenger, and neurotransmitter systems during development leading to cognitive dysfunction--developmental neurotoxicity of nicotine. 
  • Modulation of pancreatic exocrine and endocrine secretion. 
  • Monoamine mediation of cocaine-induced hypothalamo-pituitary-adrenal activation. 
  • Monosynaptic premotor circuit tracing reveals neural substrates for oro-motor coordination. 
  • Multiple roles for the active zone protein RIM1alpha in late stages of neurotransmitter release. 
  • Multivariate analysis of associations of 42 genes in ADHD, ODD and conduct disorder. 
  • NIEHS/EPA Workshops. Growth and differentiation factors. 
  • Neonatal methylmercury poisoning in the rat: effects on development of central catecholamine neurotransmitter systems. 
  • Neural factors in the development of renal function: effect of neonatal central catecholaminergic lesions with 6-hydroxydopamine. 
  • Neuroanatomic substrates of depression in the elderly. 
  • Neurobiological mechanisms in generalized anxiety disorder. 
  • Neurobiology of chronic fatigue syndrome. 
  • Neurohormonal signaling via a sulfotransferase antagonizes insulin-like signaling to regulate a Caenorhabditis elegans stress response. 
  • Neuromodulation for mood and memory: from the engineering bench to the patient bedside. 
  • Neuropeptides and neurotransmitters in Alzheimer's disease: focus on corticotrophin releasing factor. 
  • Neurosteroid transport by the organic solute transporter OSTα-OSTβ. 
  • Neurosteroids and self-reported pain in veterans who served in the U.S. Military after September 11, 2001. 
  • Neurotransmitter Imbalance in the Brain and Alzheimer's Disease Pathology. 
  • Neurotransmitter Pathway Genes in Cognitive Decline During Aging: Evidence for GNG4 and KCNQ2 Genes. 
  • Neurotransmitter identity doubt. 
  • Neurotransmitters and motor activity: effects on functional recovery after brain injury. 
  • New double-lumen polyethylene cannula for push-pull perfusion of brain tissue in vivo. 
  • New pharmacological treatments for urinary incontinence and overactive bladder. 
  • Nicotine effects on learning in zebrafish: the role of dopaminergic systems. 
  • Nicotinic systems and cognitive function. 
  • Nitric oxide in glutamate-induced compound action potential threshold shifts. 
  • Norepinephrine regulates hepatic innate immune system in leptin-deficient mice with nonalcoholic steatohepatitis. 
  • Nuclear magnetic resonance spectroscopy: new insights into the pathophysiology of mood disorders. 
  • Oral contraceptives and depressive symptomatology: biologic mechanisms. 
  • Ornithine decarboxylase: marker of neuroendocrine and neurotransmitter actions. 
  • PTSD in women is associated with a block in conversion of progesterone to the GABAergic neurosteroids allopregnanolone and pregnanolone measured in plasma. 
  • Pacing-induced heart failure: a model to study the mechanism of disease progression and novel therapy in heart failure. 
  • Perinatal dietary supplementation with a soy lecithin preparation: effects on development of central catecholaminergic neurotransmitter systems. 
  • Perinatal risk factors in the development of aggression and violence. 
  • Pharmacological approach to functional reorganization: the role of norepinephrine. 
  • Pharmacology of recovery after stroke. 
  • Phorbol esters enhance neurotransmitter-stimulated cyclic AMP production in rat brain slices. 
  • Potential effects of common drugs on stroke recovery. 
  • Pregnenolone as a novel therapeutic candidate in schizophrenia: emerging preclinical and clinical evidence. 
  • Presynaptic inhibition of spinal sensory feedback ensures smooth movement. 
  • Proof-of-concept randomized controlled trial of pregnenolone in schizophrenia. 
  • Protein phosphatase-1 regulates outward K+ currents in sensory neurons of Aplysia californica. 
  • Psychopharmacological effects in the radial-arm maze. 
  • Receptor targeting and heterogeneity at interneuronal nicotinic cholinergic synapses in vivo. 
  • Regulation of glutamate and aspartate release from the Schaffer collaterals and other projections of CA3 hippocampal pyramidal cells. 
  • Repetitive transcranial magnetic stimulation (rTMS): a noninvasive neuromodulation probe and intervention. 
  • Response: a quest and a wager. 
  • Role of neurotransmitters in seizure mechanisms in the kindling model of epilepsy. 
  • Sea urchin embryonic development provides a model for evaluating therapies against beta-amyloid toxicity. 
  • Sensory neuromodulators in functional nausea and vomiting: predictors of response. 
  • Sensory neuron signaling to the brain: properties of transmitter release from olfactory nerve terminals. 
  • Serotonergic cell signaling in an animal model of aging and depression: olfactory bulbectomy elicits different adaptations in brain regions of young adult vs aging rats. 
  • Single-voxel 1H PRESS at 4.0 T: precision and variability of measurements in anterior cingulate and hippocampus. 
  • Social anxiety disorder in review: two decades of progress. 
  • Succinylated octopamine ascarosides and a new pathway of biogenic amine metabolism in Caenorhabditis elegans. 
  • Supratrigeminal Bilaterally Projecting Neurons Maintain Basal Tone and Enable Bilateral Phasic Activation of Jaw-Closing Muscles. 
  • Surrogate end points in heart failure trials. 
  • Synaptic vesicle biogenesis, docking, and fusion: a molecular description. 
  • Synaptotagmin 9 Modulates Spontaneous Neurotransmitter Release in Striatal Neurons by Regulating Substance P Secretion. 
  • The gene encoding proline dehydrogenase modulates sensorimotor gating in mice. 
  • The kindling model of epilepsy: a review. 
  • The neurobiology of social phobia. 
  • The neurohormonal network in the RAAS can bend before breaking. 
  • The neuromuscular blocking effects of therapeutic concentrations of various antibiotics on normal rat skeletal muscle: a quantitative comparison. 
  • The neurosteroids allopregnanolone and dehydroepiandrosterone modulate resting-state amygdala connectivity. 
  • The rationale for studying transmitter interactions to understand the neural bases of cognitive function. 
  • The role of neutrophils in neuro-immune modulation. 
  • The sea urchin embryo, an invertebrate model for mammalian developmental neurotoxicity, reveals multiple neurotransmitter mechanisms for effects of chlorpyrifos: therapeutic interventions and a comparison with the monoamine depleter, reserpine. 
  • Thyrotropin releasing hormone analog TA-0910 suppresses alcohol intake in alcohol drinking African green monkeys. 
  • Transcriptional profiles reveal similarities and differences in the effects of developmental neurotoxicants on differentiation into neurotransmitter phenotypes in PC12 cells. 
  • Turnover rates of amino acid neurotransmitters in regions of rat cerebellum. 
  • Understanding the sleep-wake cycle: sleep, insomnia, and the orexin system. 
  • Unified thalamic model generates multiple distinct oscillations with state-dependent entrainment by stimulation. 
  • Uptake of (-) 3H-norepinephrine by storage vesicles prepared from whole rat brain: properties of the uptake system and its inhibition by drugs. 
  • Use of specific neuromodulators in the treatment of chronic, idiopathic cough: a systematic review. 
  • Vasopressin receptor antagonists. Therapeutic potential in the management of acute and chronic heart failure. 
  • Vasopressin: a new target for the treatment of heart failure. 
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  Keywords of People

  • Bradford, Daniel William, Professor of Psychiatry and Behavioral Sciences, Psychiatry, Child & Family Mental Health & Community Psychiatry
  • O'Connor, Christopher Michael, Adjunct Professor in the Department of Medicine, Medicine, Clinical Pharmacology