Oxidative Stress

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  Subject Areas on Research

  • 6-Hydroxydopamine injections into the nigrostriatal pathway attenuate striatal malonate and 3-nitropropionic acid lesions. 
  • A Genome-Wide Functional Genomics Approach Identifies Susceptibility Pathways to Fungal Bloodstream Infection in Humans. 
  • A Western diet induced NAFLD in LDLR(-/)(-) mice is associated with reduced hepatic glutathione synthesis. 
  • A catalytic antioxidant (AEOL 10150) attenuates expression of inflammatory genes in stroke. 
  • A colony color method identifies the vulnerability of mitochondria to oxidative damage. 
  • A comprehensive evaluation of the enzymatic and nonenzymatic antioxidant systems in childhood asthma. 
  • A controlled trial of acute effects of human exposure to traffic particles on pulmonary oxidative stress and heart rate variability. 
  • A dietary pattern that lowers oxidative stress increases antibodies to oxidized LDL: results from a randomized controlled feeding study. 
  • A flucytosine-responsive Mbp1/Swi4-like protein, Mbs1, plays pleiotropic roles in antifungal drug resistance, stress response, and virulence of Cryptococcus neoformans. 
  • A genetic analysis of nitrosative stress. 
  • A homeostatic model of oxidative damage explains paradoxes observed in earlier aging experiments: a fusion and extension of older theories of aging. 
  • A manganese porphyrin suppresses oxidative stress and extends the life span of streptozotocin-diabetic rats. 
  • A mathematical model gives insights into the effects of vitamin B-6 deficiency on 1-carbon and glutathione metabolism. 
  • A mathematical model of glutathione metabolism. 
  • A multifunctional, light-activated prochelator inhibits UVA-induced oxidative stress. 
  • A neuronal model of Alzheimer's disease: an insight into the mechanisms of oxidative stress-mediated mitochondrial injury. 
  • A new SOD mimic, Mn(III) ortho N-butoxyethylpyridylporphyrin, combines superb potency and lipophilicity with low toxicity. 
  • A new role for ATM: regulating mitochondrial function and mitophagy. 
  • A novel link between G6PD deficiency and hemolysis in patients with continuous-flow left ventricular assist devices. 
  • A population model of folate-mediated one-carbon metabolism. 
  • A regulatory hierarchy controls the dynamic transcriptional response to extreme oxidative stress in archaea. 
  • A systems biology approach towards understanding and treating non-neovascular age-related macular degeneration. 
  • ALS Multicenter Cohort Study of Oxidative Stress (ALS COSMOS): study methodology, recruitment, and baseline demographic and disease characteristics. 
  • ALS- and FTD-associated missense mutations in TBK1 differentially disrupt mitophagy. 
  • ALSUntangled No. 29: MitoQ. 
  • ALSUntangled No. 35: Hyperbaric Oxygen Therapy. 
  • ALSUntangled No. 47: RT001. 
  • APOE and the regulation of microglial nitric oxide production: a link between genetic risk and oxidative stress. 
  • ATM signals to TSC2 in the cytoplasm to regulate mTORC1 in response to ROS. 
  • ATM: genome stability, neuronal development, and cancer cross paths. 
  • Abnormal oxidative stress responses in fibroblasts from preeclampsia infants. 
  • Abrogation of adenosine A1 receptor signalling improves metabolic regulation in mice by modulating oxidative stress and inflammatory responses. 
  • Absence of carboxypeptidase E leads to adult hippocampal neuronal degeneration and memory deficits. 
  • Activation of NAD(P)H oxidase by lipid hydroperoxides: mechanism of oxidant-mediated smooth muscle cytotoxicity. 
  • Activation of transcription factors activator protein-1 and nuclear factor-kappaB by 2,3,7,8-tetrachlorodibenzo-p-dioxin. 
  • Acute Exposure to Permethrin Modulates Behavioral Functions, Redox, and Bioenergetics Parameters and Induces DNA Damage and Cell Death in Larval Zebrafish. 
  • Acute kidney injury to chronic kidney disease transition: insufficient cellular stress response. 
  • Acylation of Superoxide Dismutase 1 (SOD1) at K122 Governs SOD1-Mediated Inhibition of Mitochondrial Respiration. 
  • Addressing the Symptoms or Fixing the Problem? Developing Countermeasures against Normal Tissue Radiation Injury. 
  • Adverse outcome pathway for aminoglycoside ototoxicity in drug-resistant tuberculosis treatment. 
  • African Ancestry Gradient Is Associated with Lower Systemic F2-Isoprostane Levels. 
  • Aldosterone increases oxidant stress to impair guanylyl cyclase activity by cysteinyl thiol oxidation in vascular smooth muscle cells. 
  • Aldosterone-Induced Vascular Remodeling and Endothelial Dysfunction Require Functional Angiotensin Type 1a Receptors. 
  • Alkylation of the tumor suppressor PTEN activates Akt and β-catenin signaling: a mechanism linking inflammation and oxidative stress with cancer. 
  • Allosteric effects on oxidative and nitrosative reactions of cell-free hemoglobins. 
  • Alteration of peripheral blood monocyte gene expression in humans following diesel exhaust inhalation. 
  • Alterations in tryptophan and purine metabolism in cocaine addiction: a metabolomic study. 
  • Altered interactions of tryptophan metabolites in first-episode neuroleptic-naive patients with schizophrenia. 
  • Ameliorating the developmental neurotoxicity of chlorpyrifos: a mechanisms-based approach in PC12 cells. 
  • An SOD mimic protects NADP+-dependent isocitrate dehydrogenase against oxidative inactivation. 
  • An oxidative stress-based mechanism of doxorubicin cytotoxicity suggests new therapeutic strategies in ABC-DLBCL. 
  • An oxidized extracellular oxidation-reduction state increases Nox1 expression and proliferation in vascular smooth muscle cells via epidermal growth factor receptor activation. 
  • Androgen-induced expression of endoplasmic reticulum (ER) stress response genes in prostate cancer cells. 
  • Angiotensin 1-7 reduces mortality and rupture of intracranial aneurysms in mice. 
  • Angiotensin II type 1A receptors in vascular smooth muscle cells do not influence aortic remodeling in hypertension. 
  • Angiotensin converting enzyme 2 and the kidney. 
  • Animal models of steatohepatitis. 
  • Antiangiogenic action of redox-modulating Mn(III) meso-tetrakis(N-ethylpyridinium-2-yl)porphyrin, MnTE-2-PyP(5+), via suppression of oxidative stress in a mouse model of breast tumor. 
  • Anticancer therapeutic potential of Mn porphyrin/ascorbate system. 
  • Anticipation of oxidative damage decelerates aging in virgin female medflies: hypothesis tested by statistical modeling. 
  • Antioxidant defenses in killifish (Fundulus heteroclitus) exposed to contaminated sediments and model prooxidants: short-term and heritable responses. 
  • Antioxidant responses and NRF2 in synergistic developmental toxicity of PAHs in zebrafish. 
  • Antioxidant responses and oxidative stress in sheepshead minnow larvae exposed to Corexit 9500^® or its component surfactant, DOSS. 
  • Apolipoprotein E Exerts a Whole-Brain Protective Property by Promoting M1? Microglia Quiescence After Experimental Subarachnoid Hemorrhage in Mice. 
  • Apolipoprotein E protects against oxidative stress in mixed neuronal-glial cell cultures by reducing glutamate toxicity. 
  • Application of Oxidative Stress to a Tissue-Engineered Vascular Aging Model Induces Endothelial Cell Senescence and Activation. 
  • Ascorbic acid modulation of iron homeostasis and lysosomal function in trabecular meshwork cells. 
  • Assessment and application of the biotin switch technique for examining protein S-nitrosylation under conditions of pharmacologically induced oxidative stress. 
  • Association of Long-term Ambient Black Carbon Exposure and Oxidative Stress Allelic Variants With Intraocular Pressure in Older Men. 
  • Association of Ozone Exposure With Cardiorespiratory Pathophysiologic Mechanisms in Healthy Adults. 
  • Association of air pollution sources and aldehydes with biomarkers of blood coagulation, pulmonary inflammation, and systemic oxidative stress. 
  • Associations between superoxide dismutase, malondialdehyde and all-cause mortality in older adults: a community-based cohort study. 
  • Atherosclerosis and cancer: common molecular pathways of disease development and progression. 
  • Atherosclerosis: a cancer of the blood vessels? 
  • Attenuation of cerebral vasospasm after subarachnoid hemorrhage in mice overexpressing extracellular superoxide dismutase. 
  • Autophagic dysregulation in glaucomatous trabecular meshwork cells. 
  • Autophagy is essential to suppress cell stress and to allow BCR-Abl-mediated leukemogenesis. 
  • Baroreflex Impairment Precedes Cardiometabolic Dysfunction in an Experimental Model of Metabolic Syndrome: Role of Inflammation and Oxidative Stress. 
  • Bayesian dynamic modeling of latent trait distributions. 
  • Bioenergetic Differences in the Airway Epithelium of Lean Versus Obese Asthmatics Are Driven by Nitric Oxide and Reflected in Circulating Platelets. 
  • Biological chemistry of carbon monoxide. 
  • Biology of aortic aneurysms and dissections. 
  • Biomarkers and Cognitive Function in Children and Adolescents During Maintenance Therapy for Leukemia. 
  • Biomarkers in acutely decompensated heart failure with preserved or reduced ejection fraction. 
  • Biomarkers of oxidative stress, inflammation, and vascular dysfunction in inherited cystathionine β-synthase deficient homocystinuria and the impact of taurine treatment in a phase 1/2 human clinical trial. 
  • Bisphenol A activates EGFR and ERK promoting proliferation, tumor spheroid formation and resistance to EGFR pathway inhibition in estrogen receptor-negative inflammatory breast cancer cells. 
  • Bmp6 regulates retinal iron homeostasis and has altered expression in age-related macular degeneration. 
  • Bone morphogenetic protein 4 mediates myocardial ischemic injury through JNK-dependent signaling pathway. 
  • Bortezomib inhibits PKR-like endoplasmic reticulum (ER) kinase and induces apoptosis via ER stress in human pancreatic cancer cells. 
  • Both selenium deficiency and modest selenium supplementation lead to myocardial fibrosis in mice via effects on redox-methylation balance. 
  • Breathtaking TRP channels: TRPA1 and TRPV1 in airway chemosensation and reflex control. 
  • CAPER is vital for energy and redox homeostasis by integrating glucose-induced mitochondrial functions via ERR-α-Gabpa and stress-induced adaptive responses via NF-κB-cMYC. 
  • CBX4 Regulates Replicative Senescence of WI-38 Fibroblasts. 
  • CERKL interacts with mitochondrial TRX2 and protects retinal cells from oxidative stress-induced apoptosis. 
  • CNS bioavailability and radiation protection of normal hippocampal neurogenesis by a lipophilic Mn porphyrin-based superoxide dismutase mimic, MnTnBuOE-2-PyP5. 
  • COPD: balancing oxidants and antioxidants. 
  • CYP2E1-dependent and leptin-mediated hepatic CD57 expression on CD8+ T cells aid progression of environment-linked nonalcoholic steatohepatitis. 
  • Cadmium- and chromium-induced oxidative stress, DNA damage, and apoptotic cell death in cultured human chronic myelogenous leukemic K562 cells, promyelocytic leukemic HL-60 cells, and normal human peripheral blood mononuclear cells. 
  • Calcium oxalate and iron accumulation in sarcoidosis. 
  • Calcium-dependent cytosolic phospholipase A2 activation is implicated in neuroinflammation and oxidative stress associated with ApoE4. 
  • Calcium-dependent cytosolic phospholipase A2 activation is implicated in neuroinflammation and oxidative stress associated with ApoE4. 
  • Calorie restriction reduces oxidative stress by SIRT3-mediated SOD2 activation. 
  • Canonical Wnt signaling induces vascular endothelial dysfunction via p66Shc-regulated reactive oxygen species. 
  • Carbon monoxide reversibly alters iron homeostasis and respiratory epithelial cell function. 
  • Carbon monoxide, oxidative stress, and mitochondrial permeability pore transition. 
  • Carbon monoxide, reactive oxygen signaling, and oxidative stress. 
  • Carbon monoxide, skeletal muscle oxidative stress, and mitochondrial biogenesis in humans. 
  • Cardiac vulnerability to ischemia/reperfusion injury drastically increases in late pregnancy. 
  • Cardioprotective and antiapoptotic effects of heme oxygenase-1 in the failing heart. 
  • Cardioprotective effects of iron chelator HAPI and ROS-activated boronate prochelator BHAPI against catecholamine-induced oxidative cellular injury. 
  • Cardiorespiratory biomarker responses in healthy young adults to drastic air quality changes surrounding the 2008 Beijing Olympics. 
  • Catabolism of (2E)-4-hydroxy-2-nonenal via ω- and ω-1-oxidation stimulated by ketogenic diet. 
  • Cataract formation in a strain of rats selected for high oxidative stress. 
  • Cell senescence reduced the mechanotransduction sensitivity of porcine angular aqueous plexus cells to elevation of pressure. 
  • Cell-free hemoglobin promotes primary graft dysfunction through oxidative lung endothelial injury. 
  • Cellular energetics and mitochondrial uncoupling in canine aging. 
  • Cellular stress signaling activates type-I IFN response through FOXO3-regulated lamin posttranslational modification. 
  • Ceruloplasmin/hephaestin knockout mice model morphologic and molecular features of AMD. 
  • Cervical Vagus Nerve Stimulation Improves Neurologic Outcome After Cardiac Arrest in Mice by Attenuating Oxidative Stress and Excessive Autophagy. 
  • Challenges encountered during development of Mn porphyrin-based, potent redox-active drug and superoxide dismutase mimic, MnTnBuOE-2-PyP5+, and its alkoxyalkyl analogues. 
  • Changes in serum leptin levels as well as sICAM-1 and sVCAM-1 soluble adhesion molecules during carotid endarterectomy. 
  • Characterization of cytoprotective and toxic properties of iron chelator SIH, prochelator BSIH and their degradation products. 
  • Cholinergic Stimulation Improves Oxidative Stress and Inflammation in Experimental Myocardial Infarction. 
  • Chronic Ethanol Metabolism Inhibits Hepatic Mitochondrial Superoxide Dismutase via Lysine Acetylation. 
  • Chronic oxidative DNA damage due to DNA repair defects causes chromosomal instability in Saccharomyces cerevisiae. 
  • Chronic oxidative stress promotes GADD34-mediated phosphorylation of the TAR DNA-binding protein TDP-43, a modification linked to neurodegeneration. 
  • Cigarette Smoke Initiates Oxidative Stress-Induced Cellular Phenotypic Modulation Leading to Cerebral Aneurysm Pathogenesis. 
  • Circulating Autoantibodies in Age-Related Macular Degeneration Recognize Human Macular Tissue Antigens Implicated in Autophagy, Immunomodulation, and Protection from Oxidative Stress and Apoptosis. 
  • Classical Dendritic Cells Mediate Hypertension by Promoting Renal Oxidative Stress and Fluid Retention. 
  • Clinical review: oxygen as a signaling molecule. 
  • Colonic Epithelial-Derived Selenoprotein P Is the Source for Antioxidant-Mediated Protection in Colitis-Associated Cancer. 
  • Comparative toxicity of silver nanoparticles on oxidative stress and DNA damage in the nematode, Caenorhabditis elegans. 
  • Comparative transcriptome analysis reveals novel roles of the Ras and cyclic AMP signaling pathways in environmental stress response and antifungal drug sensitivity in Cryptococcus neoformans. 
  • Comparison of gene expression profiles induced by coarse, fine, and ultrafine particulate matter. 
  • Comparison of the abilities of ambient and manufactured nanoparticles to induce cellular toxicity according to an oxidative stress paradigm. 
  • Comparison of various iron chelators and prochelators as protective agents against cardiomyocyte oxidative injury. 
  • Comparisons of ultrafine and fine particles in their associations with biomarkers reflecting physiological pathways. 
  • Competitive apnea and its effect on the human brain: focus on the redox regulation of blood-brain barrier permeability and neuronal-parenchymal integrity. 
  • Comprehensive molecular characterization of urothelial bladder carcinoma. 
  • Comprehensive pharmacokinetic studies and oral bioavailability of two Mn porphyrin-based SOD mimics, MnTE-2-PyP5+ and MnTnHex-2-PyP5+. 
  • Concentrations of urinary 8-hydroxy-2'-deoxyguanosine and 8-isoprostane in women exposed to woodsmoke in a cookstove intervention study in San Marcos, Peru. 
  • Concerted regulation of skeletal muscle contractility by oxygen tension and endogenous nitric oxide. 
  • Concurrent production of reactive oxygen and nitrogen species by airway epithelial cells in vitro. 
  • Considerations in evaluating the physicochemical properties and transformations of inorganic nanoparticles in water. 
  • Controlled exposure to diesel exhaust causes increased nitrite in exhaled breath condensate among subjects with asthma. 
  • Copper is a potent inhibitor of both the canonical and non-canonical NFκB pathways. 
  • Correction: Mouse Models of Diet-Induced Nonalcoholic Steatohepatitis Reproduce the Heterogeneity of the Human Disease. 
  • Correlation between two markers of inflammation, serum C-reactive protein and interleukin 6, and indices of oxidative stress in patients with high risk of cardiovascular disease. 
  • Cp/Heph mutant mice have iron-induced neurodegeneration diminished by deferiprone. 
  • Critical periods for the role of oxidative stress in the developmental neurotoxicity of chlorpyrifos and terbutaline, alone or in combination. 
  • Cryptococcal cell morphology affects host cell interactions and pathogenicity. 
  • Cryptococcus neoformans mitochondrial superoxide dismutase: an essential link between antioxidant function and high-temperature growth. 
  • Cryptococcus neoformans phosphoinositide-dependent kinase 1 (PDK1) ortholog is required for stress tolerance and survival in murine phagocytes. 
  • Cultured porcine trabecular meshwork cells display altered lysosomal function when subjected to chronic oxidative stress. 
  • Cytochrome c peroxidase contributes to the antioxidant defense of Cryptococcus neoformans. 
  • Cytoprotective effects of proteasome beta5 subunit overexpression in lens epithelial cells. 
  • Cytosolic accumulation of small nucleolar RNAs (snoRNAs) is dynamically regulated by NADPH oxidase. 
  • Cytosolic hydroxymethyldihydropterin pyrophosphokinase/dihydropteroate synthase from Arabidopsis thaliana: a specific role in early development and stress response. 
  • Cytotoxic effects of Mn(III) N-alkylpyridylporphyrins in the presence of cellular reductant, ascorbate. 
  • DNA mismatch repair is required for the host innate response and controls cellular fate after influenza virus infection. 
  • Decreased Uptake and Enhanced Mitochondrial Protection Underlie Reduced Toxicity of Nanoceria in Human Monocyte-Derived Macrophages. 
  • Decreased autophagy and fuel switching occur in a senescent hepatic cell model system. 
  • Deferoxamine regulates neuroinflammation and iron homeostasis in a mouse model of postoperative cognitive dysfunction. 
  • Deficiency of optineurin enhances osteoclast differentiation by attenuating the NRF2-mediated antioxidant response. 
  • Defusing redox bombs? 
  • Degradation of engulfed mitochondria is rate-limiting in Optineurin-mediated mitophagy in neurons. 
  • Deletion of p47phox attenuates angiotensin II-induced abdominal aortic aneurysm formation in apolipoprotein E-deficient mice. 
  • Dementia and Alzheimer's disease in community-dwelling elders taking vitamin C and/or vitamin E. 
  • Dengue Virus Targets Nrf2 for NS2B3-Mediated Degradation Leading to Enhanced Oxidative Stress and Viral Replication. 
  • Dependence of the cyanobacterium Prochlorococcus on hydrogen peroxide scavenging microbes for growth at the ocean's surface. 
  • Design and Characterization of Hyperpolarized ¹⁵ N-BBCP as a H₂ O₂ -Sensing Probe. 
  • Design of Mn porphyrins for treating oxidative stress injuries and their redox-based regulation of cellular transcriptional activities. 
  • Design, mechanism of action, bioavailability and therapeutic effects of mn porphyrin-based redox modulators. 
  • Determination of residual manganese in Mn porphyrin-based superoxide dismutase (SOD) and peroxynitrite reductase mimics. 
  • Developmental neurotoxicity of perfluorinated chemicals modeled in vitro. 
  • Dietary CdSe/ZnS quantum dot exposure in estuarine fish: bioavailability, oxidative stress responses, reproduction, and maternal transfer. 
  • Dietary nitrate attenuates renal ischemia-reperfusion injuries by modulation of immune responses and reduction of oxidative stress. 
  • Dietary regulation of catabolic disposal of 4-hydroxynonenal analogs in rat liver. 
  • Differences in Reperfusion-Induced Mitochondrial Oxidative Stress and Cell Death Between Hippocampal CA1 and CA3 Subfields Are Due to the Mitochondrial Thioredoxin System. 
  • Differential gene expression in normal and transformed human mammary epithelial cells in response to oxidative stress. 
  • Differential susceptibility of fish and rat liver cells to oxidative stress and cytotoxicity upon exposure to prooxidants 
  • Differential susceptibility to acetaminophen-induced liver injury in sub-strains of C57BL/6 mice: 6N versus 6J. 
  • Discrete and complementary mechanisms of protection of beta-cells against cytokine-induced and oxidative damage achieved by bcl-2 overexpression and a cytokine selection strategy. 
  • Disrupted signaling and inhibited regeneration in obese mice with fatty livers: implications for nonalcoholic fatty liver disease pathophysiology. 
  • Disruption of Acetyl-Lysine Turnover in Muscle Mitochondria Promotes Insulin Resistance and Redox Stress without Overt Respiratory Dysfunction. 
  • Disruption of iron homeostasis in mesothelial cells after talc pleurodesis. 
  • Disruption of iron homeostasis in the lungs of transplant patients. 
  • Disruption of the Ang II type 1 receptor promotes longevity in mice. 
  • Distinct stress responses of two functional laccases in Cryptococcus neoformans are revealed in the absence of the thiol-specific antioxidant Tsa1. 
  • Distinctive RNA expression profiles in blood associated with white matter hyperintensities in brain. 
  • Distinctive adaptive response to repeated exposure to hydrogen peroxide associated with upregulation of DNA repair genes and cell cycle arrest. 
  • Disulfiram (DSF) acts as a copper ionophore to induce copper-dependent oxidative stress and mediate anti-tumor efficacy in inflammatory breast cancer. 
  • Divalent metal transporter-1 decreases metal-related injury in the lung. 
  • Diverse functions of cationic Mn(III) N-substituted pyridylporphyrins, recognized as SOD mimics. 
  • Dopamine and α-synuclein dysfunction in Smad3 null mice. 
  • Downregulation of adipose glutathione S-transferase A4 leads to increased protein carbonylation, oxidative stress, and mitochondrial dysfunction. 
  • Dry age-related macular degeneration: mechanisms, therapeutic targets, and imaging. 
  • Dual Role of Epidermal Growth Factor Receptor in Liver Injury and Regeneration after Acetaminophen Overdose in Mice. 
  • Dysregulated autophagy in the RPE is associated with increased susceptibility to oxidative stress and AMD. 
  • EGF and PDGF receptor tyrosine kinases as therapeutic targets for chronic lung diseases. 
  • Early induction of oxidative stress in mouse model of Alzheimer disease with reduced mitochondrial superoxide dismutase activity. 
  • Early onset preeclampsia in a model for human placental trophoblast. 
  • Editor's Highlight: Base Excision Repair Variants and Pesticide Exposure Increase Parkinson's Disease Risk. 
  • Editor's Highlight: Metformin Protects Against Acetaminophen Hepatotoxicity by Attenuation of Mitochondrial Oxidant Stress and Dysfunction. 
  • Effect of oxidative stress on homer scaffolding proteins. 
  • Effect of size fractionation on the toxicity of amosite and Libby amphibole asbestos. 
  • Effect of vitamin E on tamoxifen-treated breast cancer cells. 
  • Effective blue light photodynamic therapy does not affect cutaneous langerhans cell number or oxidatively damage DNA. 
  • Effects of 2 years of caloric restriction on oxidative status assessed by urinary F2-isoprostanes: The CALERIE 2 randomized clinical trial. 
  • Effects of Acetaminophen on Oxidant and Irritant Respiratory Tract Responses to Environmental Tobacco Smoke in Female Mice. 
  • Effects of Xanthine Oxidase Inhibition in Hyperuricemic Heart Failure Patients: The Xanthine Oxidase Inhibition for Hyperuricemic Heart Failure Patients (EXACT-HF) Study. 
  • Effects of a single bout of ultraendurance exercise on lipid levels and susceptibility of lipids to peroxidation in triathletes. 
  • Effects of aerobic training on oxidative status in postsurgical non-small cell lung cancer patients: a pilot study. 
  • Effects of caloric restriction on human physiological, psychological, and behavioral outcomes: highlights from CALERIE phase 2. 
  • Effects of particulate matter gamma radiation on oxidative stress biomarkers in COPD patients. 
  • Effects of personal air pollutant exposure on oxidative stress: Potential confounding by natural variation in melatonin levels. 
  • Effects of prenatal nicotine exposure on primate brain development and attempted amelioration with supplemental choline or vitamin C: neurotransmitter receptors, cell signaling and cell development biomarkers in fetal brain regions of rhesus monkeys. 
  • Effects of temperature acclimation on Pacific bluefin tuna (Thunnus orientalis) cardiac transcriptome. 
  • Electrostatic contribution in the catalysis of O2*- dismutation by superoxide dismutase mimics. MnIIITE-2-PyP5+ versus MnIIIBr8T-2-PyP+. 
  • Energy expenditure and treating obesity. 
  • Environmental toxin-linked nonalcoholic steatohepatitis and hepatic metabolic reprogramming in obese mice. 
  • ErbB1/2 tyrosine kinase inhibitor mediates oxidative stress-induced apoptosis in inflammatory breast cancer cells. 
  • Erlotinib-mediated inhibition of EGFR signaling induces metabolic oxidative stress through NOX4. 
  • Error-prone replication of oxidatively damaged DNA by a high-fidelity DNA polymerase. 
  • Estrogen receptor beta protects against in vivo injury in RPE cells. 
  • Ethanol induces redox-sensitive cell-cycle inhibitors and inhibits liver regeneration after partial hepatectomy. 
  • Evaluation of Biomarkers of Oxidative Stress and Apoptosis in Patients With Severe Methotrexate Neurotoxicity: A Case Series. 
  • Evaluation of the compounds commonly known as superoxide dismutase and catalase mimics in cellular models. 
  • Evidence for Compartmentalized Axonal Mitochondrial Biogenesis: Mitochondrial DNA Replication Increases in Distal Axons As an Early Response to Parkinson's Disease-Relevant Stress. 
  • Evolving role of biomarkers in acute cerebrovascular disease. 
  • Examination of diverse iron-chelating agents for the protection of differentiated PC12 cells against oxidative injury induced by 6-hydroxydopamine and dopamine. 
  • Exercise maintains euglycemia in association with decreased activation of c-Jun NH2-terminal kinase and serine phosphorylation of IRS-1 in the liver of ZDF rats. 
  • Exercise therapy as treatment for cardiovascular and oncologic disease after a diagnosis of early-stage cancer. 
  • Exosome markers associated with immune activation and oxidative stress in HIV patients on antiretroviral therapy. 
  • Exploring the potential role of the oxidant-activated transcription factor aryl hydrocarbon receptor in the pathogenesis of AMD. 
  • Extracellular superoxide dismutase overexpression improves behavioral outcome from closed head injury in the mouse. 
  • Extracellular superoxide dismutase overexpression protects against aging-induced cognitive impairment in mice. 
  • Extracellular superoxide dismutase regulates cardiac function and fibrosis. 
  • Extreme Acetylation of the Cardiac Mitochondrial Proteome Does Not Promote Heart Failure. 
  • F2-isoprostanes: a measure of oxidative stress in children receiving treatment for leukemia. 
  • Facilitation of robust growth of Prochlorococcus colonies and dilute liquid cultures by "helper" heterotrophic bacteria. 
  • Fatigue and Oxidative Stress in Children Undergoing Leukemia Treatment. 
  • Fatty acid desaturase activity in mature red blood cells and implications for blood storage quality. 
  • Ferruginous bodies: implications in the mechanism of fiber and particle toxicity. 
  • Fine ambient particles induce oxidative stress and metal binding genes in human alveolar macrophages. 
  • Free hemoglobin induction of pulmonary vascular disease: evidence for an inflammatory mechanism. 
  • Function of the thioredoxin proteins in Cryptococcus neoformans during stress or virulence and regulation by putative transcriptional modulators. 
  • Functional crosstalk among oxidative stress and O-GlcNAc signaling pathways. 
  • Functional significance of 8-isoprostanes in sinonasal disease and asthma. 
  • G6PD inhibition sensitizes ovarian cancer cells to oxidative stress in the metastatic omental microenvironment. 
  • Gene expression profile in circulating mononuclear cells after exposure to ultrafine carbon particles. 
  • Gene signatures of postoperative atrial fibrillation in atrial tissue after coronary artery bypass grafting surgery in patients receiving β-blockers. 
  • Gene therapy strategy for long-term myocardial protection using adeno-associated virus-mediated delivery of heme oxygenase gene. 
  • Genes of innate immunity and the biological response to inhaled ozone. 
  • Genetic Abrogation of Adenosine A3 Receptor Prevents Uninephrectomy and High Salt-Induced Hypertension. 
  • Genetic analysis of transcription-associated mutation in Saccharomyces cerevisiae. 
  • Genetic differences in oxidative stress and inflammatory responses to diet-induced obesity do not alter liver fibrosis in mice. 
  • Genetic variants and cellular stressors associated with exfoliation syndrome modulate promoter activity of a lncRNA within the LOXL1 locus. 
  • Genetics and women's health issues--the commitment of EMS to women scientists and gender-associated disease topics. 
  • Genome-wide analysis of genomic alterations induced by oxidative DNA damage in yeast. 
  • Global transcriptome profile of Cryptococcus neoformans during exposure to hydrogen peroxide induced oxidative stress. 
  • Glutamate excitotoxicity in neurons triggers mitochondrial and endoplasmic reticulum accumulation of Parkin, and, in the presence of N-acetyl cysteine, mitophagy. 
  • Glutamate mobilizes [Zn2+] through Ca2+ -dependent reactive oxygen species accumulation. 
  • Glutamine prevents apoptosis in intestinal epithelial cells and induces differential protective pathways in heat and oxidant injury models. 
  • Glutathione and zebrafish: Old assays to address a current issue. 
  • Glutathione peroxidase-deficient smooth muscle cells cause paracrine activation of normal smooth muscle cells via cyclophilin A. 
  • Glutathione regulates susceptibility to oxidant-induced mitochondrial DNA damage in human lymphocytes. 
  • Glutathione-S-transferase polymorphisms and complications of microvascular head and neck reconstruction. 
  • Growth differentiation factor 15, a marker of oxidative stress and inflammation, for risk assessment in patients with atrial fibrillation: insights from the Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation (ARISTOTLE) trial. 
  • Growth suppression and apoptosis-like cell death in Microcystis aeruginosa by H₂ O₂ : A new insight into extracellular and intracellular damage pathways. 
  • Guide for the use of nitric oxide (NO) donors as probes of the chemistry of NO and related redox species in biological systems. 
  • HGT in the human and skin commensal Malassezia: A bacterially derived flavohemoglobin is required for NO resistance and host interaction. 
  • Heme oxygenase 1 is required for mammalian iron reutilization. 
  • Heme oxygenase-1 in lung disease. 
  • Heme oxygenase-1 is upregulated in the kidney of angiotensin II-induced hypertensive rats : possible role in renoprotection. 
  • Hepatic FTO expression is increased in NASH and its silencing attenuates palmitic acid-induced lipotoxicity. 
  • Hepatitis C virus selectively perturbs the distal cholesterol synthesis pathway in a genotype-specific manner. 
  • Hepatocyte nuclear factor-4alpha mediates redox sensitivity of inducible nitric-oxide synthase gene transcription. 
  • High circulatory leptin mediated NOX-2-peroxynitrite-miR21 axis activate mesangial cells and promotes renal inflammatory pathology in nonalcoholic fatty liver disease. 
  • Higher urine nitric oxide is associated with improved outcomes in patients with acute lung injury. 
  • Homeostatic imbalance of purine catabolism in first-episode neuroleptic-naïve patients with schizophrenia. 
  • How an individual fecundity pattern looks in Drosophila and medflies. 
  • Hydrogen peroxide induces microvilli on human retinal pigment epithelial cells in culture. 
  • Hydrogen peroxide promotes aging-related platelet hyperactivation and thrombosis. 
  • Hypercapnia is essential to reduce the cerebral oxidative metabolism during extreme apnea in humans. 
  • Hypercholesterolemia Increases Colorectal Cancer Incidence by Reducing Production of NKT and γδ T Cells from Hematopoietic Stem Cells. 
  • Hypercholesterolemia induces oxidant stress that accelerates the ageing of hematopoietic stem cells. 
  • Hyperhomocysteinemia causes ER stress and impaired autophagy that is reversed by Vitamin B supplementation. 
  • Hypertension and Mitochondrial Oxidative Stress Revisited: Sirtuin 3, the Improved "Antioxidant". 
  • Hypothesis: hyperhomocysteinemia is an indicator of oxidant stress. 
  • Identification and characterization of an SKN7 homologue in Cryptococcus neoformans. 
  • Identification of JWA as a novel functional gene responsive to environmental oxidative stress induced by benzo[a]pyrene and hydrogen peroxide. 
  • Identification of a negative feedback loop in biological oxidant formation fegulated by 4-hydroxy-2-(E)-nonenal. 
  • Identification of an ovarian clear cell carcinoma gene signature that reflects inherent disease biology and the carcinogenic processes. 
  • Identification of novel candidate risk genes for myelomeningocele within the glucose homeostasis/oxidative stress and folate/one-carbon metabolism networks. 
  • Immune activation by histones: plusses and minuses in inflammation. 
  • Impact of electrostatics in redox modulation of oxidative stress by Mn porphyrins: protection of SOD-deficient Escherichia coli via alternative mechanism where Mn porphyrin acts as a Mn carrier. 
  • Increase in oxidative stress as measured by cerebrospinal fluid lipid peroxidation during treatment for childhood acute lymphoblastic leukemia. 
  • Increases in cortical glutamate concentrations in transgenic amyotrophic lateral sclerosis mice are attenuated by creatine supplementation. 
  • Individual responses to chemotherapy-induced oxidative stress. 
  • Indoor black carbon of outdoor origin and oxidative stress biomarkers in patients with chronic obstructive pulmonary disease. 
  • Inducible activation of TLR4 confers resistance to hyperoxia-induced pulmonary apoptosis. 
  • Induction of ferritin and heme oxygenase-1 by endotoxin in the lung. 
  • Induction of oxidative cell damage by photo-treatment with zinc meta N-methylpyridylporphyrin. 
  • Induction of the protective antioxidant response element pathway by 6-hydroxydopamine in vivo and in vitro. 
  • Induction of urinary excretion of 3-nitrotyrosine, a marker of oxidative stress, following administration of pyridostigmine bromide, DEET (N,N-diethyl-m-toluamide) and permethrin, alone and in combination in rats. 
  • Inflammatory and oxidative stress responses of healthy adults to changes in personal air pollutant exposure. 
  • Inflammatory and oxidative stress responses of healthy young adults to changes in air quality during the Beijing Olympics. 
  • Inflammatory mechanisms. 
  • Influence of Inflammatory and Oxidative Stress Pathways on Longitudinal Symptom Experiences in Children With Leukemia. 
  • Influence of Nitrosative Stress on Fatigue During Childhood Leukemia Treatment. 
  • Inhaled carbon monoxide and hyperoxic lung injury in rats. 
  • Inhaled ethyl nitrite prevents hyperoxia-impaired postnatal alveolar development in newborn rats. 
  • Inherited variants in mitochondrial biogenesis genes may influence epithelial ovarian cancer risk. 
  • Inhibiting triglyceride synthesis improves hepatic steatosis but exacerbates liver damage and fibrosis in obese mice with nonalcoholic steatohepatitis. 
  • Inhibition of apoptotic signaling and neointimal hyperplasia by tempol and nitric oxide synthase following vascular injury. 
  • Inhibition of p53 Sulfoconjugation Prevents Oxidative Hepatotoxicity and Acute Liver Failure. 
  • Inhibition of p66ShcA longevity gene rescues podocytes from HIV-1-induced oxidative stress and apoptosis. 
  • Inhibition of pyruvate kinase M2 by reactive oxygen species contributes to cellular antioxidant responses. 
  • Inhibition of the cardiomyocyte-specific troponin I-interacting kinase limits oxidative stress, injury, and adverse remodeling due to ischemic heart disease. 
  • Inhibitory effect of hydrogen sulfide on ozone-induced airway inflammation, oxidative stress, and bronchial hyperresponsiveness. 
  • Inorganic nitrite attenuates NADPH oxidase-derived superoxide generation in activated macrophages via a nitric oxide-dependent mechanism. 
  • Interaction between the Ah receptor and proteins binding to the AP-1-like electrophile response element (EpRE) during murine phase II [Ah] battery gene expression. 
  • Interleukin 1-induced production of nitric oxide inhibits benzenetriol-mediated oxidative injury in rat hepatocytes. 
  • Intracellular Generation of Superoxide by TiO₂ Nanoparticles Decreases Histone Deacetylase 9 (HDAC9), an Epigenetic Modifier. 
  • Intracellular uptake and associated toxicity of silver nanoparticles in Caenorhabditis elegans 
  • Intralysosomal iron induces lysosomal membrane permeabilization and cathepsin D-mediated cell death in trabecular meshwork cells exposed to oxidative stress. 
  • Intravenous allopurinol decreases myocardial oxygen consumption and increases mechanical efficiency in dogs with pacing-induced heart failure. 
  • Investigations into the loss of glutathione from lenses in organ culture. 
  • Iron homeostasis and oxidative stress in idiopathic pulmonary alveolar proteinosis: a case-control study. 
  • Iron homeostasis in the lung. 
  • Iron uptake and Nramp2/DMT1/DCT1 in human bronchial epithelial cells. 
  • Is antioxidant use protective of cognitive function in the community-dwelling elderly? 
  • Is fipronil safer than chlorpyrifos? Comparative developmental neurotoxicity modeled in PC12 cells. 
  • Is oxidative stress involved in the developmental neurotoxicity of chlorpyrifos? 
  • Is the PentaBDE replacement, tris (1,3-dichloro-2-propyl) phosphate (TDCPP), a developmental neurotoxicant? Studies in PC12 cells. 
  • Isocitrate dehydrogenase is important for nitrosative stress resistance in Cryptococcus neoformans, but oxidative stress resistance is not dependent on glucose-6-phosphate dehydrogenase. 
  • Joint effects of alcohol consumption and polymorphisms in alcohol and oxidative stress metabolism genes on risk of head and neck cancer. 
  • K63 polyubiquitination is a new modulator of the oxidative stress response. 
  • Ketamine potentiates oxidative stress and influences behavior and inflammation in response to lipolysaccharide (LPS) exposure in early life. 
  • Keto acid metabolites of branched-chain amino acids inhibit oxidative stress-induced necrosis and attenuate myocardial ischemia-reperfusion injury. 
  • Klotho, an antiaging molecule, attenuates oxidant-induced alveolar epithelial cell mtDNA damage and apoptosis. 
  • Knockdown of mouse VCAM-1 by vector-based siRNA. 
  • L-Citrulline increases nitric oxide and improves control in obese asthmatics. 
  • L-arginine or tempol supplementation improves renal and cardiovascular function in rats with reduced renal mass and chronic high salt intake. 
  • Lack of the P2X7 receptor protects against AMD-like defects and microparticle accumulation in a chronic oxidative stress-induced mouse model of AMD. 
  • Late administration of Mn porphyrin-based SOD mimic enhances diabetic complications. 
  • Leptin is key to peroxynitrite-mediated oxidative stress and Kupffer cell activation in experimental non-alcoholic steatohepatitis. 
  • Lipid-induced mitochondrial stress and insulin action in muscle. 
  • Lipids and diabetic retinopathy. 
  • Lipophilicity is a critical parameter that dominates the efficacy of metalloporphyrins in blocking the development of morphine antinociceptive tolerance through peroxynitrite-mediated pathways. 
  • Lipophilicity of potent porphyrin-based antioxidants: comparison of ortho and meta isomers of Mn(III) N-alkylpyridylporphyrins. 
  • Lipopolysaccharide induces oxidative cardiac mitochondrial damage and biogenesis. 
  • Lipopolysaccharide stimulates mitochondrial biogenesis via activation of nuclear respiratory factor-1. 
  • Liver disease in menopause. 
  • Long-term neuroprotection from a potent redox-modulating metalloporphyrin in the rat. 
  • Longitudinal stability in cigarette smokers of urinary eicosanoid biomarkers of oxidative damage and inflammation. 
  • Loss of β-catenin triggers oxidative stress and impairs hematopoietic regeneration. 
  • Low-Flow Domiciliary Oxygen as a Mechanism of Ongoing Oxidative Stress. 
  • Lower susceptibility of female mice to acetaminophen hepatotoxicity: Role of mitochondrial glutathione, oxidant stress and c-jun N-terminal kinase. 
  • Luminal alkalinization attenuates proteinuria-induced oxidative damage in proximal tubular cells. 
  • Lung injury after ozone exposure is iron dependent. 
  • Lysosomal basification and decreased autophagic flux in oxidatively stressed trabecular meshwork cells: implications for glaucoma pathogenesis. 
  • M1 polarization bias and subsequent nonalcoholic steatohepatitis progression is attenuated by nitric oxide donor DETA NONOate via inhibition of CYP2E1-induced oxidative stress in obese mice. 
  • MFN1 deacetylation activates adaptive mitochondrial fusion and protects metabolically challenged mitochondria. 
  • Malondialdehyde in exhaled breath condensate and urine as a biomarker of air pollution induced oxidative stress. 
  • Manganese Porphyrin and Radiotherapy Improves Local Tumor Response and Overall Survival in Orthotopic Murine Mammary Carcinoma Models. 
  • Manganese porphyrin redox state in endothelial cells: Resonance Raman studies and implications for antioxidant protection towards peroxynitrite. 
  • Manganese porphyrin reduces retinal injury induced by ocular hypertension in rats. 
  • Manganese porphyrins and related compounds as mimics of superoxide dismutase. 
  • Manganese superoxide dismutase is a mitochondrial fidelity protein that protects Polγ against UV-induced inactivation. 
  • Mapping oxidative DNA damage and mechanisms of repair. 
  • Mapping oxidative DNA damage using ligation-mediated polymerase chain reaction technology. 
  • Markers of oxidative status in a clinical model of oxidative assault: a pilot study in human blood following doxorubicin administration. 
  • Maternal dietary exposure to selenium nanoparticle led to malformation in offspring. 
  • Measurement of Reactive Oxygen Species by Fluorescent Probes in Pancreatic Cancer Cells. 
  • Measurement of inflammation and oxidative stress following drastic changes in air pollution during the Beijing Olympics: a panel study approach. 
  • Mechanisms of bacteriophage inactivation via singlet oxygen generation in UV illuminated fullerol suspensions. 
  • Mechanisms of cell death governed by the balance between nitrosative and oxidative stress. 
  • Mechanisms of resistance to oxidative and nitrosative stress: implications for fungal survival in mammalian hosts. 
  • Mechanisms of the antioxidant effects of nitric oxide. 
  • Memory decline of aging reduced by extracellular superoxide dismutase overexpression. 
  • Mesenchymal Stromal Cells Deficient in Autophagy Proteins Are Susceptible to Oxidative Injury and Mitochondrial Dysfunction. 
  • Metabolic Slowing and Reduced Oxidative Damage with Sustained Caloric Restriction Support the Rate of Living and Oxidative Damage Theories of Aging. 
  • Metabolic capacity regulates iron homeostasis in endothelial cells. 
  • Metabolomic changes in autopsy-confirmed Alzheimer's disease. 
  • Metalloporphyrins as therapeutic catalytic oxidoreductants in central nervous system disorders. 
  • Metallothionein alleviates cardiac dysfunction in streptozotocin-induced diabetes: role of Ca2+ cycling proteins, NADPH oxidase, poly(ADP-Ribose) polymerase and myosin heavy chain isozyme. 
  • Metformin use in patients hospitalized with COVID-19: lower inflammation, oxidative stress, and thrombotic risk markers and better clinical outcomes. 
  • Methylglyoxal augments intracellular oxidative stress in human aortic endothelial cells. 
  • Micro-RNA 21 inhibition of SMAD7 enhances fibrogenesis via leptin-mediated NADPH oxidase in experimental and human nonalcoholic steatohepatitis. 
  • Microarray analysis of murine retinal light damage reveals changes in iron regulatory, complement, and antioxidant genes in the neurosensory retina and isolated RPE. 
  • Microglial contribution to oxidative stress in Alzheimer's disease. 
  • Mitochondria and nitric oxide. 
  • Mitochondria in lung biology and pathology: more than just a powerhouse. 
  • Mitochondria-targeted antioxidant Mito-Tempo protects against acetaminophen hepatotoxicity. 
  • Mitochondrial DNA sequence associations with dementia and amyloid-β in elderly African Americans. 
  • Mitochondrial Dysfunction in Critical Illness: Implications for Nutritional Therapy. 
  • Mitochondrial GLUT10 facilitates dehydroascorbic acid import and protects cells against oxidative stress: mechanistic insight into arterial tortuosity syndrome. 
  • Mitochondrial Superoxide Dismutase Has a Protumorigenic Role in Ovarian Clear Cell Carcinoma. 
  • Mitochondrial acetylome analysis in a mouse model of alcohol-induced liver injury utilizing SIRT3 knockout mice. 
  • Mitochondrial adaptations to obesity-related oxidant stress. 
  • Mitochondrial biogenesis restores oxidative metabolism during Staphylococcus aureus sepsis. 
  • Mitochondrial biogenesis: regulation by endogenous gases during inflammation and organ stress. 
  • Mitochondrial dysfunction in human immunodeficiency virus-1 transgenic mouse cardiac myocytes. 
  • Mitochondrial dysfunction, persistently elevated levels of reactive oxygen species and radiation-induced genomic instability: a review. 
  • Mitochondrial protein adduct and superoxide generation are prerequisites for early activation of c-jun N-terminal kinase within the cytosol after an acetaminophen overdose in mice. 
  • Mitochondrial quality-control dysregulation in conditional HO-1-/- mice. 
  • Mn Porphyrin-Based Redox-Active Drugs: Differential Effects as Cancer Therapeutics and Protectors of Normal Tissue Against Oxidative Injury. 
  • Mn porphyrin-based SOD mimic, MnTnHex-2-PyP(5+), and non-SOD mimic, MnTBAP(3-), suppressed rat spinal cord ischemia/reperfusion injury via NF-κB pathways. 
  • Mn(III) meso-tetrakis-(N-ethylpyridinium-2-yl) porphyrin mitigates total body irradiation-induced long-term bone marrow suppression. 
  • Modification of lupus-associated 60-kDa Ro protein with the lipid oxidation product 4-hydroxy-2-nonenal increases antigenicity and facilitates epitope spreading. 
  • Modifications of boronic ester pro-chelators triggered by hydrogen peroxide tune reactivity to inhibit metal-promoted oxidative stress. 
  • Modifying aroylhydrazone prochelators for hydrolytic stability and improved cytoprotection against oxidative stress. 
  • Modulation of the GABA(A)-gated chloride channel by reactive oxygen species. 
  • Molecular Features Underlying Neurodegeneration Identified through In Vitro Modeling of Genetically Diverse Parkinson's Disease Patients. 
  • Molecular medicine: Defence against oxidative damage. 
  • Molecular therapies for vascular diseases. 
  • Mouse embryonic stem cells carrying one or two defective Msh2 alleles respond abnormally to oxidative stress inflicted by low-level radiation. 
  • Mouse models of diet-induced nonalcoholic steatohepatitis reproduce the heterogeneity of the human disease. 
  • Mouse translation elongation factor eEF1A-2 interacts with Prdx-I to protect cells against apoptotic death induced by oxidative stress. 
  • Muscle oxidative capacity during IL-6-dependent cancer cachexia. 
  • Mutagenic effects of abasic and oxidized abasic lesions in Saccharomyces cerevisiae. 
  • Mutational fingerprints of aging. 
  • NAD(P)H quinone oxidoreductase 1 is essential for ozone-induced oxidative stress in mice and humans. 
  • NAD(P)H quinone oxidoreductase 1 regulates neutrophil elastase-induced mucous cell metaplasia. 
  • NADPH oxidase in the renal microvasculature is a primary target for blood pressure-lowering effects by inorganic nitrate and nitrite. 
  • NK-1 antagonist reduces colonic inflammation and oxidative stress in dextran sulfate-induced colitis in rats. 
  • Nature-based botanical facial oil oxidative stress protection. 
  • Negative ions offset cardiorespiratory benefits of PM_2.5 reduction from residential use of negative ion air purifiers. 
  • Neurobehavioral radiation mitigation to standard brain cancer therapy regimens by Mn(III) n-butoxyethylpyridylporphyrin-based redox modifier. 
  • Neuroinflammation and α-synuclein dysfunction potentiate each other, driving chronic progression of neurodegeneration in a mouse model of Parkinson's disease. 
  • Neuroprotection from delayed postischemic administration of a metalloporphyrin catalytic antioxidant. 
  • Neuroprotection resulting from insufficiency of RANBP2 is associated with the modulation of protein and lipid homeostasis of functionally diverse but linked pathways in response to oxidative stress. 
  • Neuroprotective effect of curcumin in an experimental rat model of subarachnoid hemorrhage. 
  • Neuroprotective effects of creatine and cyclocreatine in animal models of Huntington's disease. 
  • Neurospora clock-controlled gene 9 (ccg-9) encodes trehalose synthase: circadian regulation of stress responses and development. 
  • Neutrophil elastase induces MUC5AC messenger RNA expression by an oxidant-dependent mechanism. 
  • New insights into oxidative stress and inflammation during diabetes mellitus-accelerated atherosclerosis. 
  • New insights provided by a comparison of impaired deformability with erythrocyte oxidative stress for sickle cell disease. 
  • Nitration of tyrosine by hydrogen peroxide and nitrite. 
  • Nitric oxide and acetaminophen-mediated oxidative injury: modulation of interleukin-1-induced nitric oxide synthesis in cultured rat hepatocytes. 
  • Nitric oxide and redox regulation in the liver: Part I. General considerations and redox biology in hepatitis. 
  • Nitric oxide and redox regulation in the liver: part II. Redox biology in pathologic hepatocytes and implications for intervention. 
  • Nitric oxide-associated regulation of hepatocyte glutathione synthesis is a guanylyl cyclase-independent event. 
  • Nitrosation and oxidation in the regulation of gene expression. 
  • Nonadditive effects of PAHs on Early Vertebrate Development: mechanisms and implications for risk assessment. 
  • Novel Neuroprotective Potential of Crocin in Neurodegenerative Disorders: An Illustrated Mechanistic Review. 
  • Novel role of 4-hydroxy-2-nonenal in AIFm2-mediated mitochondrial stress signaling. 
  • Nox2 Inhibition Regulates Stress Response and Mitigates Skeletal Muscle Fiber Atrophy during Simulated Microgravity. 
  • Nox4 NADPH oxidase contributes to smooth muscle cell phenotypes associated with unstable atherosclerotic plaques. 
  • Nrf2 inactivation enhances placental angiogenesis in a preeclampsia mouse model and improves maternal and fetal outcomes. 
  • Nuclear factor erythroid-derived factor 2-related factor 2 regulates transcription of CCAAT/enhancer-binding protein β during adipogenesis. 
  • Obstructive sleep apnea and delirium: exploring possible mechanisms. 
  • Occupational exposure to woodsmoke and oxidative stress in wildland firefighters. 
  • Olfactory receptor 2 in vascular macrophages drives atherosclerosis by NLRP3-dependent IL-1 production. 
  • Opioid use affects antioxidant activity and purine metabolism: preliminary results. 
  • Opportunity nox: the future of NADPH oxidases as therapeutic targets in cardiovascular disease. 
  • Optical and pharmacological tools to investigate the role of mitochondria during oxidative stress and neurodegeneration. 
  • Optical imaging reveals elevated intracellular chloride in hippocampal pyramidal neurons after oxidative stress. 
  • Optimizing the dose of glutamine dipeptides and antioxidants in critically ill patients: a phase I dose-finding study. 
  • Organic matter modifies biochemical but not most behavioral responses of the clam Ruditapes philippinarum to nanosilver exposure. 
  • Oval cells compensate for damage and replicative senescence of mature hepatocytes in mice with fatty liver disease. 
  • Overexpression of VMAT-2 and DT-diaphorase protects substantia nigra-derived cells against aminochrome neurotoxicity. 
  • Overexpression of a Drosophila homolog of apolipoprotein D leads to increased stress resistance and extended lifespan. 
  • Overexpression of extracellular superoxide dismutase decreases lung injury after exposure to oil fly ash. 
  • Overexpression of extracellular superoxide dismutase protects mice from radiation-induced lung injury. 
  • Overexpression of extracellular superoxide dismutase reduces acute radiation induced lung toxicity. 
  • Overexpression of hMTH in peripheral lymphocytes and risk of prostate cancer: a case-control analysis. 
  • Oxidant generation promotes iron sequestration in BEAS-2B cells exposed to asbestos. 
  • Oxidant stress from nitric oxide synthase-3 uncoupling stimulates cardiac pathologic remodeling from chronic pressure load. 
  • Oxidants, antioxidants and the ischemic brain. 
  • Oxidative DNA base damage in MCF-10A breast epithelial cells at clinically achievable concentrations of doxorubicin. 
  • Oxidative DNA damage and DNA repair enzyme expression are inversely related in murine models of fatty liver disease. 
  • Oxidative DNA damage during night shift work. 
  • Oxidative DNA damage during sleep periods among nightshift workers. 
  • Oxidative Stress Response and Delirium after Cardiac Surgery: Can Circulating Biomarkers Refine New Therapeutic Paradigms? 
  • Oxidative Stress and Thrombosis during Aging: The Roles of Oxidative Stress in RBCs in Venous Thrombosis. 
  • Oxidative Stress and Total Antioxidant Status During Internal Carotid Artery Clamping with or without Shunting: An Experimental Pilot Study. 
  • Oxidative Stress, Motor Abilities, and Behavioral Adjustment in Children Treated for Acute Lymphoblastic Leukemia. 
  • Oxidative changes in cerebral spinal fluid phosphatidylcholine during treatment for acute lymphoblastic leukemia. 
  • Oxidative damage is a potential cause of cone cell death in retinitis pigmentosa. 
  • Oxidative damage to macromolecules in human Parkinson disease and the rotenone model. 
  • Oxidative damage-induced inflammation initiates age-related macular degeneration. 
  • Oxidative mechanisms contributing to the developmental neurotoxicity of nicotine and chlorpyrifos. 
  • Oxidative metabolism in rat hepatocytes and mitochondria during sepsis. 
  • Oxidative metabolism in sepsis and sepsis syndrome. 
  • Oxidative stress activates anion exchange protein 2 and AP-1 in airway epithelial cells. 
  • Oxidative stress and adenine nucleotide control of mitochondrial permeability transition. 
  • Oxidative stress and covalent modification of protein with bioactive aldehydes. 
  • Oxidative stress and executive function in children receiving chemotherapy for acute lymphoblastic leukemia. 
  • Oxidative stress and inflammation contribute to lung toxicity after a common breast cancer chemotherapy regimen. 
  • Oxidative stress and nerve function after cardiopulmonary bypass in patients with diabetes. 
  • Oxidative stress and neurobehavioral problems in pediatric acute lymphoblastic leukemia patients undergoing chemotherapy. 
  • Oxidative stress and oval cell accumulation in mice and humans with alcoholic and nonalcoholic fatty liver disease. 
  • Oxidative stress during acetaminophen hepatotoxicity: Sources, pathophysiological role and therapeutic potential. 
  • Oxidative stress from diverse developmental neurotoxicants: antioxidants protect against lipid peroxidation without preventing cell loss. 
  • Oxidative stress impact on barrier function of porcine angular aqueous plexus cell monolayers. 
  • Oxidative stress in cardiovascular disease. 
  • Oxidative stress in diseases of the human cornea. 
  • Oxidative stress in human abdominal aortic aneurysms: a potential mediator of aneurysmal remodeling. 
  • Oxidative stress in toxicology: established mammalian and emerging piscine model systems. 
  • Oxidative stress in two populations of killifish (Fundulus heteroclitus) with differing contaminant exposure histories. 
  • Oxidative stress increases hepatocyte iNOS gene transcription and promoter activity. 
  • Oxidative stress induces itch via activation of transient receptor potential subtype ankyrin 1 in mice. 
  • Oxidative stress mediates monocrotaline-induced alterations in tenascin expression in pulmonary artery endothelial cells. 
  • Oxidative stress promotes SIRT1 recruitment to the GADD34/PP1α complex to activate its deacetylase function. 
  • Oxidative stress survival in a clinical Saccharomyces cerevisiae isolate is influenced by a major quantitative trait nucleotide. 
  • Oxidative stress, oxidative balance score, and hypertension among a racially diverse population. 
  • Oxidative stress-induced expression and modulation of Phosphatase of Regenerating Liver-1 (PRL-1) in mammalian retina. 
  • Oxidative stress-mediated NFκB phosphorylation upregulates p62/SQSTM1 and promotes retinal pigmented epithelial cell survival through increased autophagy. 
  • Oxidized lipid-mediated alterations in proteoglycan metabolism in cultured pulmonary endothelial cells. 
  • Oxidized low-density lipoprotein induces apoptosis in endothelial progenitor cells by inactivating the phosphoinositide 3-kinase/Akt pathway. 
  • Oxygen toxicity and iron accumulation in the lungs of mice lacking heme oxygenase-2. 
  • Oxygen-induced mitochondrial biogenesis in the rat hippocampus. 
  • Ozone inhalation promotes CX3CR1-dependent maturation of resident lung macrophages that limit oxidative stress and inflammation. 
  • PGC1-α over-expression prevents metabolic alterations and soleus muscle atrophy in hindlimb unloaded mice. 
  • PKC1 is essential for protection against both oxidative and nitrosative stresses, cell integrity, and normal manifestation of virulence factors in the pathogenic fungus Cryptococcus neoformans. 
  • PM2.5 constituents and oxidative DNA damage in humans. 
  • PRDX6 attenuates oxidative stress- and TGFbeta-induced abnormalities of human trabecular meshwork cells. 
  • Parallel induction of heme oxygenase-1 and chemoprotective phase 2 enzymes by electrophiles and antioxidants: regulation by upstream antioxidant-responsive elements (ARE). 
  • Pathogenesis of alcohol-induced liver disease: classical concepts and recent advances. 
  • Pathogenic triad in COPD: oxidative stress, protease-antiprotease imbalance, and inflammation. 
  • Perfluorooctyl bromide (perflubron) attenuates oxidative injury to biological and nonbiological systems. 
  • Peroxisome proliferator-activated receptor γ co-activator 1-α as a critical co-activator of the murine hepatic oxidative stress response and mitochondrial biogenesis in Staphylococcus aureus sepsis. 
  • Peroxynitrite formation and decreased catalase activity in autoimmune MRL-lpr/lpr mice. 
  • Persistent oxidative stress due to absence of uncoupling protein 2 associated with impaired pancreatic beta-cell function. 
  • Persistent systemic inflammation in chronic critical illness. 
  • Personal Exposure to PM_2.5 Oxidative Potential in Association with Pulmonary Pathophysiologic Outcomes in Children with Asthma. 
  • Personal exposure to particulate PAHs and anthraquinone and oxidative DNA damages in humans. 
  • Phagocyte-generated superoxide reduces Fe3+ to displace it from the surface of asbestos. 
  • Pharmacological blockade of ASCT2-dependent glutamine transport leads to antitumor efficacy in preclinical models. 
  • Phase 1 Study of a Sulforaphane-Containing Broccoli Sprout Homogenate for Sickle Cell Disease. 
  • Phosphorylation of Ser158 regulates inflammatory redox-dependent hepatocyte nuclear factor-4alpha transcriptional activity. 
  • Placental IDO and oxidative damage in pre-eclampsia: fresh chicken or fresh eggs? Preface. 
  • Plasma creatinine and oxidative stress biomarkers in amyotrophic lateral sclerosis. 
  • Pollutant particles enhanced H2O2 production from NAD(P)H oxidase and mitochondria in human pulmonary artery endothelial cells. 
  • Polyglutamine expansion inhibits respiration by increasing reactive oxygen species in isolated mitochondria. 
  • Postlipopolysaccharide oxidative damage of mitochondrial DNA. 
  • Posttranslational, translational, and transcriptional responses to nitric oxide stress in Cryptococcus neoformans: implications for virulence. 
  • Potential role of lysosomal dysfunction in the pathogenesis of primary open angle glaucoma. 
  • Prenatal nicotine exposure in rhesus monkeys compromises development of brainstem and cardiac monoamine pathways involved in perinatal adaptation and sudden infant death syndrome: amelioration by vitamin C. 
  • Prevention of influenza-induced lung injury in mice overexpressing extracellular superoxide dismutase. 
  • Pro-oxidant status and Nrf2 levels in psoriasis vulgaris skin tissues and dimethyl fumarate-treated HaCaT cells. 
  • Pro-thrombotic and pro-oxidant effects of diet-induced hyperhomocysteinemia. 
  • Prochelator BHAPI protects cells against paraquat-induced damage by ROS-triggered iron chelation. 
  • Prochelators triggered by hydrogen peroxide provide hexadentate iron coordination to impede oxidative stress. 
  • Production of hydroxyl radical in the hippocampus after CO hypoxia or hypoxic hypoxia in the rat. 
  • Progesterone, Inflammatory Cytokine (TNF-α), and Oxidative Stress (H2O2) Regulate Progesterone Receptor Membrane Component 1 Expression in Fetal Membrane Cells. 
  • Proteasome inhibition by chronic oxidative stress in human trabecular meshwork cells. 
  • Protecting the permeability pore and mitochondrial biogenesis. 
  • Protection from nitrosative stress by yeast flavohemoglobin. 
  • Protection from nitrosative stress: a central role for microbial flavohemoglobin. 
  • Protection from oxidation enhances the survival of cultured mesencephalic neurons. 
  • Protective role of fructose in the metabolism of astroglial C6 cells exposed to hydrogen peroxide. 
  • Protective role of ortho-substituted Mn(III) N-alkylpyridylporphyrins against the oxidative injury induced by tert-butylhydroperoxide. 
  • Protective role of transient pore openings in calcium handling by cardiac mitochondria. 
  • Pulmonary fibrosis and ferruginous bodies associated with exposure to synthetic fibers. 
  • Pure MnTBAP selectively scavenges peroxynitrite over superoxide: comparison of pure and commercial MnTBAP samples to MnTE-2-PyP in two models of oxidative stress injury, an SOD-specific Escherichia coli model and carrageenan-induced pleurisy. 
  • Purinergic receptor X7 is a key modulator of metabolic oxidative stress-mediated autophagy and inflammation in experimental nonalcoholic steatohepatitis. 
  • Quantification of the oxidative damage biomarker 2,3-dinor-8-isoprostaglandin-F(2alpha) in human urine using liquid chromatography-tandem mass spectrometry. 
  • Quitting smoking raises whole blood glutathione. 
  • RAS and ROS in rhabdomyosarcoma. 
  • REST and stress resistance in ageing and Alzheimer's disease. 
  • RETRACTED: NAD(P)H:quinone oxidoreductase 1 protects lungs from oxidant-induced emphysema in mice. 
  • ROS signaling, oxidative stress and Nrf2 in pancreatic beta-cell function. 
  • Racial differences in urinary F2-isoprostane levels and the cross-sectional association with BMI. 
  • Radiation activates HIF-1 to regulate vascular radiosensitivity in tumors: role of reoxygenation, free radicals, and stress granules. 
  • Radioprotection of the brain white matter by Mn(III) n-Butoxyethylpyridylporphyrin-based superoxide dismutase mimic MnTnBuOE-2-PyP5+. 
  • Radioprotective effects of amifostine on acute and chronic esophageal injury in rodents. 
  • Raising the bar: how HIF-1 helps determine tumor radiosensitivity. 
  • Ranbp2 haploinsufficiency mediates distinct cellular and biochemical phenotypes in brain and retinal dopaminergic and glia cells elicited by the Parkinsonian neurotoxin, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). 
  • Rapid up-regulation of peptide elongation factor EF-1alpha protein levels is an immediate early event during oxidative stress-induced apoptosis. 
  • Reactive Acyl-CoA Species Modify Proteins and Induce Carbon Stress. 
  • Reactive oxygen species produced by liver mitochondria of rats in sepsis. 
  • Reassessing serum urate targets in the management of refractory gout: can you go too low? 
  • Recent progress in metabolic signaling pathways regulating aging and life span. 
  • Recognition and assessment of shift work disorder. 
  • Redox modulation of oxidative stress by Mn porphyrin-based therapeutics: the effect of charge distribution. 
  • Redox regulation of mitochondrial biogenesis. 
  • Redox regulation of neuronal migration in a Down Syndrome model. 
  • Redox regulation of the rat hepatocyte iNOS promoter. 
  • Redox-Active Mn Porphyrin-based Potent SOD Mimic, MnTnBuOE-2-PyP(5+), Enhances Carbenoxolone-Mediated TRAIL-Induced Apoptosis in Glioblastoma Multiforme. 
  • Redox-sensitive E2 Rad6 controls cellular response to oxidative stress via K63-linked ubiquitination of ribosomes. 
  • Reduced stress defense in heme oxygenase 1-deficient cells. 
  • Reduction of oxidative stress attenuates lipoapoptosis exacerbated by hypoxia in human hepatocytes. 
  • Regulation of mitochondrial biogenesis and its intersection with inflammatory responses. 
  • Regulatory Mechanism of the Atypical AP-1-Like Transcription Factor Yap1 in Cryptococcus neoformans. 
  • Relationships between cycling hypoxia, HIF-1, angiogenesis and oxidative stress. 
  • Relevance of the ability of fructose 1,6-bis(phosphate) to sequester ferrous but not ferric ions. 
  • Renal denervation attenuates NADPH oxidase-mediated oxidative stress and hypertension in rats with hydronephrosis. 
  • Resistance to cerebral ischemic injury in UCP2 knockout mice: evidence for a role of UCP2 as a regulator of mitochondrial glutathione levels. 
  • Resveratrol Protects Against Hydroquinone-Induced Oxidative Threat in Retinal Pigment Epithelial Cells. 
  • Resveratrol prevention of oxidative stress damage to lens epithelial cell cultures is mediated by forkhead box O activity. 
  • Resveratrol prevents protein nitration and release of endonucleases from mitochondria during acetaminophen hepatotoxicity. 
  • Resveratrol prevents the expression of glaucoma markers induced by chronic oxidative stress in trabecular meshwork cells. 
  • Retinal pigment epithelial cell death by the alternative complement cascade: role of membrane regulatory proteins, calcium, PKC, and oxidative stress. 
  • Rhabdomyolysis and hemolysis associated with sickle cell trait and glucose-6-phosphate dehydrogenase deficiency. 
  • Rheumatoid arthritis T cell and muscle oxidative metabolism associate with exercise-induced changes in cardiorespiratory fitness. 
  • Ribonomic analysis of human Pum1 reveals cis-trans conservation across species despite evolution of diverse mRNA target sets. 
  • Role of Cryptococcus neoformans Rho1 GTPases in the PKC1 signaling pathway in response to thermal stress. 
  • Role of Mitochondrial Oxidative Stress in Glucose Tolerance, Insulin Resistance, and Cardiac Diastolic Dysfunction. 
  • Role of alternative oxidase gene in pathogenesis of Cryptococcus neoformans. 
  • Role of endogenous melatonin in pathophysiologic and oxidative stress responses to personal air pollutant exposures in asthmatic children. 
  • Role of fructose in the adaptation of plants to cold-induced oxidative stress. 
  • Role of guanylate cyclase modulators in decompensated heart failure. 
  • Role of oxidative stress in a rat model of radiation-induced erectile dysfunction. 
  • Roles of Progesterone Receptor Membrane Component 1 in Oxidative Stress-Induced Aging in Chorion Cells. 
  • Roles of mitochondrial ROS and NLRP3 inflammasome in multiple ozone-induced lung inflammation and emphysema. 
  • Rpl13a small nucleolar RNAs regulate systemic glucose metabolism. 
  • S-Nitrosylation of Sarcomeric Proteins Depresses Myofilament Ca2+)Sensitivity in Intact Cardiomyocytes. 
  • Saccharomyces cerevisiae: population divergence and resistance to oxidative stress in clinical, domesticated and wild isolates. 
  • Seasonal variations in air pollution particle-induced inflammatory mediator release and oxidative stress. 
  • Selective inhibition of eukaryotic translation initiation factor 2 alpha dephosphorylation potentiates fatty acid-induced endoplasmic reticulum stress and causes pancreatic beta-cell dysfunction and apoptosis. 
  • Selective killing of cancer cells harboring mutant RAS by concomitant inhibition of NADPH oxidase and glutathione biosynthesis. 
  • Sequestration of mitochondrial iron by silica particle initiates a biological effect. 
  • Serine/threonine phosphorylation regulates HNF-4alpha-dependent redox-mediated iNOS expression in hepatocytes. 
  • Sex-Specific Mechanisms of Resistance Vessel Endothelial Dysfunction Induced by Cardiometabolic Risk Factors. 
  • Signal transduction pathways in hyperoxia-induced lung cell death. 
  • Silver impairs neurodevelopment: studies in PC12 cells. 
  • Silver nanocolloids disrupt medaka embryogenesis through vital gene expressions. 
  • Silver nanoparticle toxicity is related to coating materials and disruption of sodium concentration regulation. 
  • Silver nanoparticles compromise neurodevelopment in PC12 cells: critical contributions of silver ion, particle size, coating, and composition. 
  • Similarities and differences in the pathogenesis of alcoholic and nonalcoholic steatohepatitis. 
  • Simultaneous proteomic profiling of four different growth states of human fibroblasts, using amine-reactive isobaric tagging reagents and tandem mass spectrometry. 
  • Single-Cell Transcriptional Heterogeneity of Neutrophils During Acute Pulmonary Cryptococcus neoformans Infection. 
  • Sirt3 regulates metabolic flexibility of skeletal muscle through reversible enzymatic deacetylation. 
  • Site-Specific K63 Ubiquitinomics Provides Insights into Translation Regulation under Stress. 
  • Skeletal muscle sarcoplasmic reticulum contains a NADH-dependent oxidase that generates superoxide. 
  • Small nucleolar RNAs U32a, U33, and U35a are critical mediators of metabolic stress. 
  • Sparstolonin B attenuates early liver inflammation in experimental NASH by modulating TLR4 trafficking in lipid rafts via NADPH oxidase activation. 
  • Specific regulation of noncanonical p38alpha activation by Hsp90-Cdc37 chaperone complex in cardiomyocyte. 
  • Stanniocalcin-1 is a Modifier of Oxygen-Induced Retinopathy Severity. 
  • Stem cell therapy for liver disease: parameters governing the success of using bone marrow mesenchymal stem cells. 
  • Steroid-sensitive nephrotic syndrome candidate gene CLVS1 regulates podocyte oxidative stress and endocytosis. 
  • Stress response of the trabecular meshwork. 
  • Stressed-out podocytes in diabetes? 
  • Structural impact of K63 ubiquitin on yeast translocating ribosomes under oxidative stress. 
  • Subcellular organelle lipidomics in TLR-4-activated macrophages. 
  • Subtype specific estrogen receptor action protects against changes in MMP-2 activation in mouse retinal pigmented epithelial cells. 
  • Succination of Protein Disulfide Isomerase Links Mitochondrial Stress and Endoplasmic Reticulum Stress in the Adipocyte During Diabetes. 
  • Superoxide dismutase-3 promotes full expression of the EPO response to hypoxia. 
  • Superoxide enhances interleukin 1beta-mediated transcription of the hepatocyte-inducible nitric oxide synthase gene. 
  • Superoxide production in vascular smooth muscle contributes to oxidative stress and impaired relaxation in atherosclerosis. 
  • Suppression of PGC-1α Is Critical for Reprogramming Oxidative Metabolism in Renal Cell Carcinoma. 
  • Suppression of oxidative stress by β-hydroxybutyrate, an endogenous histone deacetylase inhibitor. 
  • Supraspinal inactivation of mitochondrial superoxide dismutase is a source of peroxynitrite in the development of morphine antinociceptive tolerance. 
  • Survival of retinal pigment epithelium after exposure to prolonged oxidative injury: a detailed gene expression and cellular analysis. 
  • Sustained stress response after oxidative stress in trabecular meshwork cells. 
  • Switching off IMMP2L signaling drives senescence via simultaneous metabolic alteration and blockage of cell death. 
  • Synergistic activity of the SRC family kinase inhibitor dasatinib and oxaliplatin in colon carcinoma cells is mediated by oxidative stress. 
  • Synthetic alpha-synuclein fibrils cause mitochondrial impairment and selective dopamine neurodegeneration in part via iNOS-mediated nitric oxide production. 
  • Synthetic surfactant scavenges oxidants and protects against hyperoxic lung injury. 
  • Systemic administration of the iron chelator deferiprone protects against light-induced photoreceptor degeneration in the mouse retina. 
  • Systemic markers of oxidative status and colorectal adenomatous polyps. 
  • Systemic oxidative stress, as measured by urinary allantoin and F(2)-isoprostanes, is not increased in Down syndrome. 
  • T cells and macrophages responding to oxidative damage cooperate in pathogenesis of a mouse model of age-related macular degeneration. 
  • TRPV4 activation of endothelial nitric oxide synthase resists nonalcoholic fatty liver disease by blocking CYP2E1-mediated redox toxicity. 
  • Taking HAART in HIVAN: will protease inhibitor sparing regimens alter renal outcome? 
  • Targeted Nrf2 activation therapy with RTA 408 enhances regenerative capacity of diabetic wounds. 
  • Targeting ABL1-mediated oxidative stress adaptation in fumarate hydratase-deficient cancer. 
  • Targeting T cell (oxidative) metabolism to improve immunity to viral infection in the context of obesity. 
  • Targeting T-cell oxidative metabolism to improve influenza survival in a mouse model of obesity. 
  • Targeting Tau Mitigates Mitochondrial Fragmentation and Oxidative Stress in Amyotrophic Lateral Sclerosis. 
  • Temporal dynamics of host molecular responses differentiate symptomatic and asymptomatic influenza a infection. 
  • Temporal onset of hypoxia and oxidative stress after pulmonary irradiation. 
  • Teratogenic, bioenergetic, and behavioral effects of exposure to total particulate matter on early development of zebrafish (Danio rerio) are not mimicked by nicotine. 
  • Tetrahydroindenoindole inhibits the progression of diabetes in mice. 
  • Th1 inflammatory response with altered expression of profibrotic and vasoactive mediators in AT1A and AT1B double-knockout mice. 
  • The Abl family kinases: mechanisms of regulation and signaling. 
  • The Host Response to Viral Infections Reveals Common and Virus-Specific Signatures in the Peripheral Blood. 
  • The Longitudinal Parallel Process Analysis of Biomarkers of Oxidative Stress, Symptom Clusters, and Cognitive Function in Children With Leukemia. 
  • The Nrf2-ARE pathway: an indicator and modulator of oxidative stress in neurodegeneration. 
  • The Role of Vitamin D and Oxidative Stress in Chronic Kidney Disease. 
  • The RosR transcription factor is required for gene expression dynamics in response to extreme oxidative stress in a hypersaline-adapted archaeon. 
  • The autophagic lysosomal system in outflow pathway physiology and pathophysiology. 
  • The cardiopulmonary effects of ambient air pollution and mechanistic pathways: a comparative hierarchical pathway analysis. 
  • The cardiovascular disease continuum validated: clinical evidence of improved patient outcomes: part I: Pathophysiology and clinical trial evidence (risk factors through stable coronary artery disease). 
  • The cooperative roles of inflammation and oxidative stress in the pathogenesis of hypertension. 
  • The copper chelator ATN-224 induces peroxynitrite-dependent cell death in hematological malignancies. 
  • The effects of tempol on cyclophosphamide-induced oxidative stress in rat micturition reflexes. 
  • The endothelial mineralocorticoid receptor: mediator of the switch from vascular health to disease. 
  • The future of biology in driving the field of hyperthermia. 
  • The hydrolytic susceptibility of prochelator BSIH in aqueous solutions. 
  • The impact of household air cleaners on the oxidative potential of PM_2.5 and the role of metals and sources associated with indoor and outdoor exposure. 
  • The impact of human and mouse differences in NOS2 gene expression on the brain's redox and immune environment. 
  • The importance of Bcl-xL in the survival of human RPE cells. 
  • The influence of air cleaners on indoor particulate matter components and oxidative potential in residential households in Beijing. 
  • The influence of oxidative stress on symptom occurrence, severity, and distress during childhood leukemia treatment. 
  • The inhibition of the kynurenine pathway prevents behavioral disturbances and oxidative stress in the brain of adult rats subjected to an animal model of schizophrenia. 
  • The involvement of superoxide and iNOS-derived NO in cardiac dysfunction induced by pro-inflammatory cytokines. 
  • The iron cycle and oxidative stress in the lung. 
  • The mechanism of silver nanoparticle toxicity is dependent on dissolved silver and surface coating in Caenorhabditis elegans 
  • The multifaceted roles of nitric oxide in cancer. 
  • The oral iron chelator deferiprone protects against iron overload-induced retinal degeneration. 
  • The oral iron chelator deferiprone protects against systemic iron overload-induced retinal degeneration in hepcidin knockout mice. 
  • The oxidative stress product carboxyethylpyrrole potentiates TLR2/TLR1 inflammatory signaling in macrophages. 
  • The oxidative stress response. 
  • The relationship between intracellular and plasma levels of folate and metabolites in the methionine cycle: a model. 
  • The role of oxidative damage in mitochondria during aging: a review. 
  • The role of oxidative stress, inflammation and acetaminophen exposure from birth to early childhood in the induction of autism. 
  • The role of proteolytic cellular systems in trabecular meshwork homeostasis. 
  • The sirtuins, oxidative stress and aging: an emerging link. 
  • The transcriptional response to oxidative stress during vertebrate development: effects of tert-butylhydroquinone and 2,3,7,8-tetrachlorodibenzo-p-dioxin. 
  • The uric acid transporter SLC2A9 is a direct target gene of the tumor suppressor p53 contributing to antioxidant defense. 
  • The use of tocofersolan as a rescue agent in larval zebrafish exposed to benzo[a]pyrene in early development. 
  • Thermal stability of the prototypical Mn porphyrin-based superoxide dismutase mimic and potent oxidative-stress redox modulator Mn(III) meso-tetrakis(N-ethylpyridinium-2-yl)porphyrin chloride, MnTE-2-PyP(5+). 
  • Thioredoxin and hematologic malignancies. 
  • Thioredoxin reductase is essential for viability in the fungal pathogen Cryptococcus neoformans. 
  • Thioredoxin-interacting protein (Txnip) is a feedback regulator of S-nitrosylation. 
  • Thyroid hormone induction of mitochondrial activity is coupled to mitophagy via ROS-AMPK-ULK1 signaling. 
  • Toll-like receptor 4 mediates mitochondrial DNA damage and biogenic responses after heat-inactivated E. coli. 
  • Toward the development of prochelators as fluorescent probes of copper-mediated oxidative stress. 
  • Transcription factor Nrf2 hyperactivation in early-phase renal ischemia-reperfusion injury prevents tubular damage progression. 
  • Transcription factor Nrg1 mediates capsule formation, stress response, and pathogenesis in Cryptococcus neoformans. 
  • Transcriptional control of glyoxalase 1 by Nrf2 provides a stress-responsive defence against dicarbonyl glycation. 
  • Transcriptional control of mitochondrial biogenesis and its interface with inflammatory processes. 
  • Treating gout with pegloticase, a PEGylated urate oxidase, provides insight into the importance of uric acid as an antioxidant in vivo. 
  • TrmB Family Transcription Factor as a Thiol-Based Regulator of Oxidative Stress Response. 
  • Tumor necrosis factor-alpha is a potent endogenous mutagen that promotes cellular transformation. 
  • Tumor necrosis factor-α modulates cerebral aneurysm formation and rupture. 
  • Twenty-Four-Hour Cardiovascular Effects of Electronic Cigarettes Compared With Cigarette Smoking in Dual Users. 
  • Two faces of nitric oxide: implications for cellular mechanisms of oxygen toxicity. 
  • Two glutathione peroxidases in the fungal pathogen Cryptococcus neoformans are expressed in the presence of specific substrates. 
  • Ultrastructural characterization and Fourier analysis of fiber cell cytoplasm in the hyperbaric oxygen treated guinea pig lens opacification model. 
  • Up-regulated expression of extracellular matrix remodeling genes in phagocytically challenged trabecular meshwork cells. 
  • Urinary F2-isoprostanes and the risk of hypertension. 
  • Urinary F2-isoprostanes are not associated with increased risk of type 2 diabetes. 
  • Urinary F2-isoprostanes, obesity, and weight gain in the IRAS cohort. 
  • Urinary Isoprostane Levels and Age-Related Macular Degeneration. 
  • Urinary biomarkers of oxidative status in a clinical model of oxidative assault. 
  • Urinary biomarkers of oxidative status. 
  • Urinary mutagenicity and other biomarkers of occupational smoke exposure of wildland firefighters and oxidative stress. 
  • Utility of Growth Differentiation Factor-15, A Marker of Oxidative Stress and Inflammation, in Chronic Heart Failure: Insights From the HF-ACTION Study. 
  • Vascular biology: the past 50 years. 
  • Viscera affectum anno: the gut beyond eating behaviours. 
  • Vitamin E inhibits abdominal aortic aneurysm formation in angiotensin II-infused apolipoprotein E-deficient mice. 
  • Vitamin E therapy of acute CCl4-induced hepatic injury in mice is associated with inhibition of nuclear factor kappa B binding. 
  • WIPI1 is a conserved mediator of right ventricular failure. 
  • What if cell culture media do not mimic in vivo redox settings? 
  • X-ray crystallographic analysis of adipocyte fatty acid binding protein (aP2) modified with 4-hydroxy-2-nonenal. 
  • Xanthine oxidase inhibition for hyperuricemic heart failure patients: design and rationale of the EXACT-HF study. 
  • ZAP-70-dependent and -independent activation of Erk in Jurkat T cells. Differences in signaling induced by H2o2 and Cd3 cross-linking. 
  • microRNA miR-144 modulates oxidative stress tolerance and associates with anemia severity in sickle cell disease. 
  • n-3 Canola oil effectively replaces fish oil as a new safe dietary source of DHA in feed for juvenile Atlantic salmon. 
  • p38: the link between the kappa-opioid receptor and dysphoria. 
• 

  Keywords of People

  • Abbruzzese, James, D. C. I. Distinguished Professor of Medical Oncology, Medicine, Medical Oncology
  • Bowes Rickman, Catherine, George and Geneva Boguslavsky Distinguished Professor of Eye Research, Cell Biology
  • Choi, Steven Sok, Associate Professor of Medicine, Medicine, Gastroenterology
  • Farsiu, Sina, Professor in the Department of Biomedical Engineering, Electrical and Computer Engineering
  • Ferreira, Paulo Alexandre, Associate Professor in Ophthalmology, Pathology
  • Grambow, Steven C., Associate Professor of Biostatistics & Bioinformatics, Biostatistics & Bioinformatics
  • Hirschey, Matthew, Associate Professor of Medicine, Cell Biology
  • Hoffman, Maureane, Professor of Pathology, Immunology
  • Hsu-Kim, Heileen, Professor in the Department of Civil and Environmental Engineering, Civil and Environmental Engineering
  • Jordt, Sven Eric, Associate Professor in Anesthesiology, Pharmacology & Cancer Biology
  • Laskowitz, Daniel Todd, Professor of Neurology, Duke Science & Society
  • Linardic, Corinne Mary, Associate Professor of Pediatrics, Cell Biology
  • Moorman, Patricia Gripka, Professor Emeritus in Family Medicine and Community Health, Duke Cancer Institute
  • Schmid, Amy K., David M. Goodner Associate Professor, Duke Science & Society
  • Shinohara, Mari L., Associate Professor of Immunology, Cell Biology
  • Sparks, Matthew A., Associate Professor of Medicine, Medicine, Nephrology
  • Toth, Cynthia Ann, Joseph A.C. Wadsworth Distinguished Professor of Ophthalmology, Biomedical Engineering
  • Turi, Jennifer Lilly, Associate Professor of Pediatrics, Pediatrics, Critical Care Medicine