Th1 Cells
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Subject Areas on Research
- A highly polarized TH2 bladder response to infection promotes epithelial repair at the expense of preventing new infections.
- AML-loaded DC generate Th1-type cellular immune responses in vitro.
- Activation of src-family tyrosine kinases by LPS regulates cytokine production in dendritic cells by controlling AP-1 formation.
- Alpha-melanocyte-stimulating hormone suppresses antigen-stimulated T cell production of gamma-interferon.
- Altered balance between Th17 and Th1 cells at mucosal sites predicts AIDS progression in simian immunodeficiency virus-infected macaques.
- An approach to modelling in immunology.
- B-lymphocyte depletion reduces skin fibrosis and autoimmunity in the tight-skin mouse model for systemic sclerosis.
- CD38-NAD+Axis Regulates Immunotherapeutic Anti-Tumor T Cell Response.
- CD8 positive T cells influence antigen-specific immune responses through the expression of chemokines.
- Cell adhesion molecules regulate fibrotic process via Th1/Th2/Th17 cell balance in a bleomycin-induced scleroderma model.
- Characterization of CD4 and CD8 T cell responses in MuSK myasthenia gravis.
- Characterization of effector T cells in dry eye disease.
- Coadministration of IL-12 or IL-10 expression cassettes drives immune responses toward a Th1 phenotype.
- Critical role of NOD2 in regulating the immune response to Staphylococcus aureus.
- Cytokine expression by first-trimester human chorionic villi.
- Cytokine transcriptional events during helper T cell subset differentiation.
- Cytokines in murine lyme carditis: Th1 cytokine expression follows expression of proinflammatory cytokines in a susceptible mouse strain.
- Cytosolic phospholipase A2 alpha-deficient mice are resistant to experimental autoimmune encephalomyelitis.
- DGK α and ζ Activities Control TH1 and TH17 Cell Differentiation.
- Decreased interferon-alpha production in HIV-infected patients correlates with numerical and functional deficiencies in circulating type 2 dendritic cell precursors.
- Diacylglycerol kinase zeta regulates microbial recognition and host resistance to Toxoplasma gondii.
- Dietary factors alter hepatic innate immune system in mice with nonalcoholic fatty liver disease.
- Differential modulation of Th1- and Th2-related cytokine mRNA expression by a synthetic peptide homologous to a conserved domain within retroviral envelope protein.
- Differential reconstitution of T cell subsets following immunodepleting treatment with alemtuzumab (anti-CD52 monoclonal antibody) in patients with relapsing-remitting multiple sclerosis.
- Distinct Regulation of Th17 and Th1 Cell Differentiation by Glutaminase-Dependent Metabolism.
- Donor specific bone marrow cells suppress lymphocyte reactivity to donor antigens and differentially modulate TH1 and TH2 cytokine gene expression in the responder cell population.
- Donor-specific bone marrow cells suppress lymphocyte reactivity to donor antigens and differentially modulate TH1 and TH2 cytokine gene expression in the responder cell population.
- Effect of desiccating environmental stress versus systemic muscarinic AChR blockade on dry eye immunopathogenesis.
- Engagement of monocytes, NK cells, and CD4+ Th1 cells by ALVAC-SIV vaccination results in a decreased risk of SIVmac251 vaginal acquisition.
- Enhanced Immune Responses to HIV-1 Envelope Elicited by a Vaccine Regimen Consisting of Priming with Newcastle Disease Virus Expressing HIV gp160 and Boosting with gp120 and SOSIP gp140 Proteins.
- Enhanced activation of human dendritic cells by inducible CD40 and Toll-like receptor-4 ligation.
- Enhanced type 1 immunity after secondary viral challenge in mice primed as neonates.
- Enhancing the immunostimulatory function of dendritic cells by transfection with mRNA encoding OX40 ligand.
- Functional genomics identifies type I interferon pathway as central for host defense against Candida albicans.
- Glucose-regulated protein 94/glycoprotein 96 elicits bystander activation of CD4+ T cell Th1 cytokine production in vivo.
- H2-DMalpha(-/-) mice show the importance of major histocompatibility complex-bound peptide in cardiac allograft rejection.
- Human S100A15 splice variants are differentially expressed in inflammatory skin diseases and regulated through Th1 cytokines and calcium.
- Immunoregulation of CNS autoimmunity by helminth and mycobacterial infections.
- Impact of Th1 CD4 Follicular Helper T Cell Skewing on Antibody Responses to an HIV-1 Vaccine in Rhesus Macaques.
- In vitro priming and expansion of cytomegalovirus-specific Th1 and Tc1 T cells from naive cord blood lymphocytes.
- In vivo molecular analysis of cytokines in a murine model of ocular onchocerciasis. I. Up-regulation of IL-4 and IL-5 mRNAs and not IL-2 and IFN gamma mRNAs in the cornea due to experimental interstitial keratitis.
- In vivo protein expression and immune responses generated by DNA vaccines expressing mycobacterial antigens fused with a reporter protein.
- Increased levels of IgE and autoreactive, polyreactive IgG in wild rodents: implications for the hygiene hypothesis.
- Infection with Mycobacterium bovis BCG diverts traffic of myelin oligodendroglial glycoprotein autoantigen-specific T cells away from the central nervous system and ameliorates experimental autoimmune encephalomyelitis.
- Inflammatory Th1 and Th17 in the Intestine Are Each Driven by Functionally Specialized Dendritic Cells with Distinct Requirements for MyD88.
- Inhibitory role of CD19 in the progression of experimental autoimmune encephalomyelitis by regulating cytokine response.
- Interleukin-7 permits Th1/Tc1 maturation and promotes ex vivo expansion of cord blood T cells: a critical step toward adoptive immunotherapy after cord blood transplantation.
- Modular utilization of distal cis-regulatory elements controls Ifng gene expression in T cells activated by distinct stimuli.
- Modulation of amplitude and direction of in vivo immune responses by co-administration of cytokine gene expression cassettes with DNA immunogens.
- Molecular dissection of the miR-17-92 cluster's critical dual roles in promoting Th1 responses and preventing inducible Treg differentiation.
- Monocyte-derived CD40 expression is regulated by interferon-γ/interferon-γ receptor-1 pathway when acting as a bridge during their interaction with T cells and allogeneic endothelial cells.
- NLRC3 expression in dendritic cells attenuates CD4+ T cell response and autoimmunity.
- Peyer's patch CD8+ memory T cells secrete T helper type 1 and type 2 cytokines and provide help for immunoglobulin secretion.
- Regulation of T-helper-cell lineage development by osteopontin: the inside story.
- Regulation of mucosal and systemic antibody responses by T helper cell subsets, macrophages, and derived cytokines following oral immunization with live recombinant Salmonella.
- Reprograming immunity to food allergens.
- Rim Pathway-Mediated Alterations in the Fungal Cell Wall Influence Immune Recognition and Inflammation.
- Role of T-bet in commitment of TH1 cells before IL-12-dependent selection.
- Role of interleukin 12 and costimulators in T cell anergy in vivo.
- Simvastatin inhibits secretion of Th17-polarizing cytokines and antigen presentation by DCs in patients with relapsing remitting multiple sclerosis.
- Stability of Th1 and Th2 populations.
- Statins' immunomodulatory potential against Th17 cell-mediated autoimmune response.
- Studies on the mechanism and specificity of the effect of the synthetic random copolymer GLAT on graft-versus-host disease.
- Synthesis and Biological Evaluation of Subglutinol Analogs for Immunomodulatory Agents.
- T helper 2-dominant antilymphoma immune response is associated with fatal outcome.
- T-bet-dependent expression of osteopontin contributes to T cell polarization.
- TCF1 Is Required for the T Follicular Helper Cell Response to Viral Infection.
- Tacrolimus inhibits Th1 and Th17 responses in MuSK-antibody positive myasthenia gravis patients.
- Tgf-beta inhibits activation and uveitogenicity of primary but not of fully polarized retinal antigen-specific memory-effector T cells.
- Th1 inflammatory response with altered expression of profibrotic and vasoactive mediators in AT1A and AT1B double-knockout mice.
- Th1-Polarized, Dengue Virus-Activated Human Mast Cells Induce Endothelial Transcriptional Activation and Permeability.
- The differential role of L-selectin and ICAM-1 in Th1-type and Th2-type contact hypersensitivity.
- The role of IL12 in helper T-cell differentiation.
- Titrating T-cell epitopes within self-assembled vaccines optimizes CD4+ helper T cell and antibody outputs.
- Transcriptional regulation of T lymphocyte development and function.
- Type B CpG oligodeoxynucleotides induce Th1 responses to peanut antigens: modulation of sensitization and utility in a truncated immunotherapy regimen in mice.
- Viral infection of cells within the tumor microenvironment mediates antitumor immunotherapy via selective TBK1-IRF3 signaling.
- [LMP-420, a new therapeutic approach for cerebral malaria?].
- [Study of immunoregulation of dendritic cells in allergic rhinitis].
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Keywords of People
- Cianciolo, George James, Associate Professor in Pathology, Pathology
- Shinohara, Mari L., Associate Professor of Immunology, Immunology
- Zhong, Xiaoping, Professor of Pediatrics, Immunology