Th2 Cells
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Subject Areas on Research
- A highly polarized TH2 bladder response to infection promotes epithelial repair at the expense of preventing new infections.
- Aerobic exercise attenuates airway inflammatory responses in a mouse model of atopic asthma.
- Aging is associated with a rapid decline in frequency, alterations in subset composition, and enhanced Th2 response in CD1d-restricted NKT cells from human peripheral blood.
- Allergen-induced airway disease is mouse strain dependent.
- An anti-inflammatory role for carbon monoxide and heme oxygenase-1 in chronic Th2-mediated murine colitis.
- An approach to modelling in immunology.
- B-lymphocyte depletion reduces skin fibrosis and autoimmunity in the tight-skin mouse model for systemic sclerosis.
- Beta-arrestin-2 regulates the development of allergic asthma.
- Blocking CCR7 at the ocular surface impairs the pathogenic contribution of dendritic cells in allergic conjunctivitis.
- CD19 expression in B cells regulates atopic dermatitis in a mouse model.
- CD4+Thy1- thymocytes with a Th-type 2 cytokine response.
- Cell adhesion molecules regulate fibrotic process via Th1/Th2/Th17 cell balance in a bleomycin-induced scleroderma model.
- Chronic graft-versus-host disease.
- Cryptococcus neoformans hyperfilamentous strain is hypervirulent in a murine model of cryptococcal meningoencephalitis.
- Cytokine transcriptional events during helper T cell subset differentiation.
- Dietary factors alter hepatic innate immune system in mice with nonalcoholic fatty liver disease.
- Differential modulation of Th1- and Th2-related cytokine mRNA expression by a synthetic peptide homologous to a conserved domain within retroviral envelope protein.
- Donor specific bone marrow cells suppress lymphocyte reactivity to donor antigens and differentially modulate TH1 and TH2 cytokine gene expression in the responder cell population.
- Donor-specific bone marrow cells suppress lymphocyte reactivity to donor antigens and differentially modulate TH1 and TH2 cytokine gene expression in the responder cell population.
- Effect of desiccating environmental stress versus systemic muscarinic AChR blockade on dry eye immunopathogenesis.
- Effects of allergic airway disease on mouse adenovirus type 1 respiratory infection.
- Elevated IgE and atopy in patients treated for early-onset ADA-SCID.
- Endogenous IL-12 is required for induction and expression of experimental autoimmune uveitis.
- Exacerbation of established pulmonary fibrosis in a murine model by gammaherpesvirus.
- Exposure to particulate hexavalent chromium exacerbates allergic asthma pathology.
- G-CSF induces a potentially tolerant gene and immunophenotype profile in T cells in vivo.
- Generation of melanoma-specific, cytotoxic CD4(+) T helper 2 cells: requirement of both HLA-DR15 and Fas antigens on melanomas for their lysis by Th2 cells.
- Glycopeptide epitope facilitates HIV-1 envelope specific humoral immune responses by eliciting T cell help.
- H2-DMalpha(-/-) mice show the importance of major histocompatibility complex-bound peptide in cardiac allograft rejection.
- Hepatic allograft-derived Kupffer cells regulate T cell response in rats.
- IL-13 in asthma and allergic disease: asthma phenotypes and targeted therapies.
- IL-4 induces differentiation and expansion of Th2 cytokine-producing eosinophils.
- IL-9: Function, Sources, and Detection.
- Immune deviation and Fas-mediated deletion limit antitumor activity after multiple dendritic cell vaccinations in mice.
- Immunoregulation of CNS autoimmunity by helminth and mycobacterial infections.
- Impact of Th1/Th2 cytokine polarity induced by invariant NKT cells on the incidence of pregnancy loss in mice.
- Impairing oral tolerance promotes allergy and anaphylaxis: a new murine food allergy model.
- In vivo molecular analysis of cytokines in a murine model of ocular onchocerciasis. I. Up-regulation of IL-4 and IL-5 mRNAs and not IL-2 and IFN gamma mRNAs in the cornea due to experimental interstitial keratitis.
- Increased regulatory T-cell fraction amidst a diminished CD4 compartment explains cellular immune defects in patients with malignant glioma.
- Induction of maternal tolerance to fetal alloantigens by RANTES production.
- Inhibition of NF-kappaB activation reduces the tissue effects of transgenic IL-13.
- Inhibitory role of CD19 in the progression of experimental autoimmune encephalomyelitis by regulating cytokine response.
- Intercellular adhesion molecule-1 deficiency attenuates the development of skin fibrosis in tight-skin mice.
- Interleukin-13 disrupts type 2 pneumocyte stem cell activity.
- Lung effector memory and activated CD4+ T cells display enhanced proliferation in surfactant protein A-deficient mice during allergen-mediated inflammation.
- Modulation of amplitude and direction of in vivo immune responses by co-administration of cytokine gene expression cassettes with DNA immunogens.
- Mucosal adjuvant effect of cholera toxin in mice results from induction of T helper 2 (Th2) cells and IL-4.
- NIP45 controls the magnitude of the type 2 T helper cell response.
- Nasal peanut+ CpG immunotherapy enhances peanut-specific IFN-γ in Th2 cells and IL-10 in non-Th2 cells in mice.
- Nociceptive neurons regulate innate and adaptive immunity and neuropathic pain through MyD88 adapter.
- Ocular allergy modulation to hi-dose antigen sensitization is a Treg-dependent process.
- Pepsinized cashew proteins are hypoallergenic and immunogenic and provide effective immunotherapy in mice with cashew allergy.
- Peyer's patch CD8+ memory T cells secrete T helper type 1 and type 2 cytokines and provide help for immunoglobulin secretion.
- Positive selection on a human-specific transcription factor binding site regulating IL4 expression.
- Protein Phosphatase 1α and Cofilin Regulate Nuclear Translocation of NF-κB and Promote Expression of the Anti-Inflammatory Cytokine Interleukin-10 by T Cells.
- Protein/AS01B vaccination elicits stronger, more Th2-skewed antigen-specific human T follicular helper cell responses than heterologous viral vectors.
- Renal Effects of Cytokines in Hypertension.
- Reprograming immunity to food allergens.
- Role of early growth response-1 (Egr-1) in interleukin-13-induced inflammation and remodeling.
- Selective autophagy of the adaptor protein Bcl10 modulates T cell receptor activation of NF-κB.
- Severely blunted allergen-induced pulmonary Th2 cell response and lung hyperresponsiveness in type 1 transient receptor potential channel-deficient mice.
- Stability and function of regulatory T cells expressing the transcription factor T-bet.
- Stability of Th1 and Th2 populations.
- Statins' immunomodulatory potential against Th17 cell-mediated autoimmune response.
- Studies on the mechanism and specificity of the effect of the synthetic random copolymer GLAT on graft-versus-host disease.
- T helper 2-dominant antilymphoma immune response is associated with fatal outcome.
- T(H)2 bias: Mina tips the balance.
- T-helper 2 and 3 type immunity to trophoblast in successful in vitro fertilization-embryo transfer.
- Targeting In Vivo Metabolic Vulnerabilities of Th2 and Th17 Cells Reduces Airway Inflammation.
- The Wnt Antagonist Dickkopf-1 Promotes Pathological Type 2 Cell-Mediated Inflammation.
- The common mucosal immune system: from basic principles to enteric vaccines with relevance for the female reproductive tract.
- The differential role of L-selectin and ICAM-1 in Th1-type and Th2-type contact hypersensitivity.
- Titrating T-cell epitopes within self-assembled vaccines optimizes CD4+ helper T cell and antibody outputs.
- Tonic LAT-HDAC7 Signals Sustain Nur77 and Irf4 Expression to Tune Naive CD4 T Cells.
- Transcriptional profiling of whole blood and serum protein analysis of mice exposed to the neurotoxin Pacific Ciguatoxin-1.
- Transcriptome profiling reveals Th2 bias and identifies endogenous itch mediators in poison ivy contact dermatitis.
- Transcriptomic analysis of atopic dermatitis in African Americans is characterized by Th2/Th17-centered cutaneous immune activation.
- [Antitumoral action of interferons and interleukins in combination with radiotherapy. Part I: immunologic basis].
- [Study of immunoregulation of dendritic cells in allergic rhinitis].
- β-Arrestin-2-Dependent Signaling Promotes CCR4-mediated Chemotaxis of Murine T-Helper Type 2 Cells.
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Keywords of People
- Cianciolo, George James, Associate Professor Emeritus of Pathology, Pathology
- Sampson, John Howard, Robert H., M.D. and Gloria Wilkins Professor of Neurosurgery, in the School of Medicine, Biomedical Engineering
- Wray, Gregory Allan, Professor of Biology, Evolutionary Anthropology
- Zhong, Xiaoping, Professor of Pediatrics, Immunology