SEER Program

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  Subject Areas on Research

  • 40-year incidence trends for oropharyngeal squamous cell carcinoma in the United States. 
  • A Bedside Risk Calculator to Preoperatively Distinguish Follicular Thyroid Carcinoma from Follicular Variant of Papillary Thyroid Carcinoma. 
  • A Nomogram for Predicting Cancer-Specific Survival of TNM 8th Edition Stage I Non-small-cell Lung Cancer. 
  • A comparison of relative survival and cause-specific survival methods to measure net survival in cancer populations. 
  • Adult Glioma Incidence and Survival by Race or Ethnicity in the United States From 2000 to 2014. 
  • Advanced imaging and hospice use in end-of-life cancer care. 
  • Age-related disparities in the use of radiotherapy for treatment of localized soft tissue sarcoma. 
  • Age-specific occurrence of HPV16- and HPV18-related cervical cancer. 
  • Aggressive variants of papillary thyroid cancer: incidence, characteristics and predictors of survival among 43,738 patients. 
  • Akt expression may predict favorable prognosis in cholangiocarcinoma. 
  • An exponential growth in incidence of thyroid cancer: trends and impact of CT imaging. 
  • Analysis of primary CD30+ cutaneous lymphoproliferative disease and survival from the Surveillance, Epidemiology, and End Results database. 
  • Annual financial impact of well-differentiated thyroid cancer care in the United States. 
  • Are Small Reimbursement Changes Enough to Change Cancer Care? Reimbursement Variation in Prostate Cancer Treatment. 
  • Association Between Use of the 21-Gene Recurrence Score Assay and Receipt of Chemotherapy Among Medicare Beneficiaries With Early-Stage Breast Cancer, 2005-2009. 
  • Association of 21-Gene Assay (OncotypeDX) Testing and Receipt of Chemotherapy in the Medicare Breast Cancer Patient Population Following Initial Adoption. 
  • Association of Black Race With Prostate Cancer-Specific and Other-Cause Mortality. 
  • Association of Current Opioid Use With Serious Adverse Events Among Older Adult Survivors of Breast Cancer. 
  • Association of Helicobacter pylori infection and diet on the risk of gastric cancer: a case-control study in Hawaii. 
  • Associations of cancer and other chronic medical conditions with SF-6D preference-based scores in Medicare beneficiaries. 
  • Availability of Healthcare Resources and Colorectal Cancer Outcomes Among Non-Hispanic White and Non-Hispanic Black Adults. 
  • Benefit of adjuvant chemotherapy after resection of stage II (T1-2N1M0) non-small cell lung cancer in elderly patients. 
  • Breast cancer as heterogeneous disease: contributing factors and carcinogenesis mechanisms. 
  • Breast cancer deaths averted over 3 decades. 
  • Breast cancer survival in African-American women by hormone receptor subtypes. 
  • CBTRUS Statistical Report: Primary Brain and Central Nervous System Tumors Diagnosed in the United States in 2008-2012. 
  • Cancer Outcomes in DCIS Patients Without Locoregional Treatment. 
  • Cancer in primary immunodeficiency diseases: Cancer incidence in the United States Immune Deficiency Network Registry. 
  • Cancer incidence among union carpenters in New Jersey. 
  • Cancer screening in the elderly. 
  • Cancer statistics for adults aged 85 years and older, 2019. 
  • Cancer, comorbidities, and health-related quality of life of older adults. 
  • Causes of death in long-term survivors of head and neck cancer. 
  • Cervical lymph node metastasis and papillary thyroid carcinoma: does the compartment involved affect survival? Experience from the SEER database. 
  • Characteristics of patients diagnosed with both melanoma and renal cell cancer. 
  • Characterizing the impact of 25 years of DCIS treatment. 
  • Chemotherapy Costs and 21-Gene Recurrence Score Genomic Testing Among Medicare Beneficiaries With Early-Stage Breast Cancer, 2005 to 2011. 
  • Chemotherapy characteristics are important predictors of primary prophylactic CSF administration in older patients with breast cancer. 
  • Chronic lymphocytic leukemia in African Americans. 
  • Cigarette smoking and health-related quality of life in Medicare beneficiaries. 
  • Clinical outcomes of molecularly confirmed clear cell sarcoma from a single institution and in comparison with data from the Surveillance, Epidemiology, and End Results registry. 
  • Coexistence of urinary incontinence and major depressive disorder with health-related quality of life in older Americans with and without cancer. 
  • Cohort Contributions to Race- and Gender-Specific Trends in the Incidence of Hepatocellular Carcinoma in the USA. 
  • Colorectal Cancer Statistics From the Veterans Affairs Central Cancer Registry. 
  • Comorbidity burden and guideline-concordant care for breast cancer. 
  • Comparison of Neoadjuvant and Adjuvant Chemotherapy in Muscle-invasive Bladder Cancer. 
  • Comparison of demographic characteristics, surgical resection patterns, and survival outcomes for veterans and nonveterans with non-small cell lung cancer in the Pacific Northwest. 
  • Comparison of the use and results of sentinel lymph node biopsy in children and young adults with melanoma. 
  • Competing Mortality in Patients With Neuroendocrine Tumors. 
  • Complete prevalence of malignant primary brain tumors registry data in the United States compared with other common cancers, 2010. 
  • Completeness and concordancy of WHO grade assignment for brain and central nervous system tumors in the United States, 2004-2011. 
  • Completeness of required site-specific factors for brain and CNS tumors in the Surveillance, Epidemiology and End Results (SEER) 18 database (2004-2012, varying). 
  • Concurrent Opioid and Benzodiazepine Prescriptions Among Older Women Diagnosed With Breast Cancer. 
  • Conditional survival after diagnosis with malignant brain and central nervous system tumor in the United States, 1995-2012. 
  • Conditional survival probabilities for patients with resected pancreatic adenocarcinoma. 
  • Connect MM Registry as a national reference for United States multiple myeloma patients. 
  • Connect MM® - the Multiple Myeloma Disease Registry: incidence of second primary malignancies in patients treated with lenalidomide. 
  • Cost impact of oral capecitabine compared to intravenous taxane-based chemotherapy in first-line metastatic breast cancer. 
  • Cost-effectiveness of opportunistic salpingectomy for ovarian cancer prevention. 
  • Costs of Cancer Care Across the Disease Continuum. 
  • Costs, effectiveness, and workload impact of management strategies for women with an adnexal mass. 
  • County-level cumulative environmental quality associated with cancer incidence. 
  • Daily intake of antioxidants in relation to survival among adult patients diagnosed with malignant glioma. 
  • Decreased cancer-independent life expectancy in the head and neck cancer population. 
  • Descriptive characteristics of prostate cancer in patients with a history of primary male breast cancer - a SEER analysis. 
  • Dietary carbohydrate intake, glycaemic load, glycaemic index and ovarian cancer risk in African-American women. 
  • Discrete improvement in racial disparity in survival among patients with stage IV colorectal cancer: a 21-year population-based analysis. 
  • Does anatomic subsite influence oral cavity cancer mortality? A SEER database analysis. 
  • Does surgery improve outcomes for esophageal squamous cell carcinoma? An analysis using the surveillance epidemiology and end results registry from 1998 to 2008. 
  • Dysphagia prevalence and associated survival differences in older patients with lung cancer: A SEER-Medicare population-based study. 
  • Editorial comment. 
  • Effect of primary prophylactic G-CSF use on systemic therapy administration for elderly breast cancer patients. 
  • Effectiveness of radiotherapy for elderly patients with anaplastic gliomas. 
  • Effects of Cancer Stage and Treatment Differences on Racial Disparities in Survival From Colon Cancer: A United States Population-Based Study. 
  • Enrollment Trends and Disparity Among Patients With Lung Cancer in National Clinical Trials, 1990 to 2012. 
  • Epidemiologic support for melanoma heterogeneity using the Surveillance, Epidemiology, and End Results Program. 
  • Epidemiologic support for melanoma heterogeneity using the surveillance, epidemiology, and end results program. 
  • Evaluating the number of stages in development of squamous cell and adenocarcinomas across cancer sites using human population-based cancer modeling. 
  • Evaluation of Racial, Ethnic, and Socioeconomic Associations With Treatment and Survival in Uveal Melanoma, 2004-2014. 
  • Evaluation of the 8th edition American Joint Commission on Cancer (AJCC) staging system for patients with intrahepatic cholangiocarcinoma: A surveillance, epidemiology, and end results (SEER) analysis. 
  • Examining potential gaps in supportive medication use for US and foreign-born Hispanic women with breast cancer. 
  • Excess diagnosis of non-Hodgkin's lymphoma during spring in the USA. 
  • Exploring the Relationship Between Patient Age and Cancer-Specific Survival in Papillary Thyroid Cancer: Rethinking Current Staging Systems. 
  • Exploring the association between melanoma and glioma risks. 
  • Extent of surgery for low-risk thyroid cancer in the elderly: Equipoise in survival but not in short-term outcomes. 
  • Fatigue in breast cancer survivors two to five years post diagnosis: a HEAL Study report. 
  • Females have the survival advantage in glioblastoma. 
  • Generalizability of trial results to elderly Medicare patients with advanced solid tumors (Alliance 70802). 
  • Glioma incidence and survival variations by county-level socioeconomic measures. 
  • Gonadotropin-releasing hormone agonist overuse: urologists' response to reimbursement and characteristics associated with persistent overuse. 
  • Granulocyte-colony stimulating factor use and medical costs after initial adjuvant chemotherapy in older patients with early-stage breast cancer. 
  • Health Care Disparities in Cancer Patients Receiving Radiation: Changes in Insurance Status After Medicaid Expansion Under the Affordable Care Act. 
  • Human epidermal growth factor receptor-2 and estrogen receptor expression, a demonstration project using the residual tissue repository of the Surveillance, Epidemiology, and End Results (SEER) program. 
  • Impact of Age on Long-Term Outcomes of Surgery for Malignant Pleural Mesothelioma. 
  • Impact of Examined Lymph Node Count on Precise Staging and Long-Term Survival of Resected Non-Small-Cell Lung Cancer: A Population Study of the US SEER Database and a Chinese Multi-Institutional Registry. 
  • Impact of Surveillance After Lobectomy for Lung Cancer on Disease Detection and Survival. 
  • Impact of age at diagnosis on racial disparities in endometrial cancer patients. 
  • Impact of cancer center accreditation on outcomes of patients undergoing resection for hepatocellular carcinoma: A SEER-Medicare analysis. 
  • Impact of cancer on health-related quality of life of older Americans. 
  • Impact of diagnosis and treatment of clinically localized prostate cancer on health-related quality of life for older Americans: a population-based study. 
  • Impact of extent of surgery on survival for papillary thyroid cancer patients younger than 45 years. 
  • Impact of hysterectomy and bilateral oophorectomy prevalence on rates of cervical, uterine, and ovarian cancer among American Indian and Alaska Native women, 1999-2004. 
  • Impact of mesothelioma histologic subtype on outcomes in the Surveillance, Epidemiology, and End Results database. 
  • Implications for Breast Cancer Restaging Based on the 8th Edition AJCC Staging Manual. 
  • Implications of Cystectomy Travel Distance for Hospital Readmission and Survival. 
  • Incidence and Risk of Second Primary Malignant Neoplasm After a First Head and Neck Squamous Cell Carcinoma. 
  • Incidence and survival trends for medulloblastomas in the United States from 2001 to 2013. 
  • Incidence of Ductal Carcinoma In Situ in the United States, 2000-2014. 
  • Incidence patterns for primary malignant spinal cord gliomas: a Surveillance, Epidemiology, and End Results study. 
  • Initial Trends in the Use of the 21-Gene Recurrence Score Assay for Patients With Breast Cancer in the Medicare Population, 2005-2009. 
  • Insurance coverage among women diagnosed with a gynecologic malignancy before and after implementation of the Affordable Care Act. 
  • Insurance status, stage of presentation, and survival among female patients with head and neck cancer. 
  • Intensity-modulated radiation therapy, proton therapy, or conformal radiation therapy and morbidity and disease control in localized prostate cancer. 
  • Invasive Epithelial Ovarian Cancer Survival by Histotype and Disease Stage. 
  • Investigating racial disparities in use of NK1 receptor antagonists to prevent chemotherapy-induced nausea and vomiting among women with breast cancer. 
  • Is it my cancer or am i just getting older?: Impact of cancer on age-related health conditions of older cancer survivors. 
  • Is prostate cancer stage migration continuing for black men in the PSA era? 
  • Lifetime Occurrence of Brain Metastases Arising from Lung, Breast, and Skin Cancers in the Elderly: A SEER-Medicare Study. 
  • Longitudinal Trends in Costs of Palliative Radiation for Metastatic Prostate Cancer. 
  • Low-Risk Thyroid Cancer in Elderly: Total Thyroidectomy/RAI Predominates but Lacks Survival Advantage. 
  • Low-grade astrocytomas: the prognostic value of fibrillary, gemistocytic, and protoplasmic tumor histology. 
  • Malignant struma ovarii: a population-level analysis of a large series of 68 patients. 
  • Marital status independently predicts testis cancer survival--an analysis of the SEER database. 
  • Medullary thyroid microcarcinoma: a population-level analysis of 310 patients. 
  • Medulloblastoma and birth date: evaluation of 3 U.S. datasets. 
  • Merkel cell carcinoma: identification of prognostic factors unique to tumors located in the head and neck based on analysis of SEER data. 
  • Modeling the natural history of ductal carcinoma in situ based on population data. 
  • Morbidity risks among older adults with pre-existing age-related diseases. 
  • Mortality After Breast Cancer Among Survivors of Childhood Cancer: A Report From the Childhood Cancer Survivor Study. 
  • Multiple myeloma in the very old: an IASIA conference report. 
  • National Trends for Reoperation in Older Patients with Glioblastoma. 
  • New stochastic carcinogenesis model with covariates: an approach involving intracellular barrier mechanisms. 
  • Opioid Use Disorder and Overdose in Older Adults With Breast, Colorectal, or Prostate Cancer. 
  • Outcomes and Costs for Women After Breast Cancer: Preparing for Improved Survivorship of Medicare Beneficiaries. 
  • Outcomes of Active Surveillance for Ductal Carcinoma in Situ: A Computational Risk Analysis. 
  • Pancreatic cancer mortality in Egypt: comparison to the United States pancreatic cancer mortality rates. 
  • Partitioning of time trends in prevalence and mortality of lung cancer. 
  • Patterns of Treatment and Outcomes for Definitive Therapy of Early Stage Non-Small Cell Lung Cancer. 
  • Patterns of care for elderly men diagnosed with favorable-risk prostate cancer from 2004 to 2008: a population-based analysis. 
  • Patterns of care in older patients with squamous cell carcinoma of the head and neck: a surveillance, epidemiology, and end results-medicare analysis. 
  • Pediatric Acute Lymphoblastic Leukemia, Version 2.2020, NCCN Clinical Practice Guidelines in Oncology. 
  • Pelvic exenteration for the treatment of locally advanced colorectal and bladder malignancies in the modern era. 
  • Postoperative Surveillance in Older Adults With T1N0M0 Low-risk Papillary Thyroid Cancer. 
  • Pre-diagnosis health-related quality of life, surgery, and survival in women with advanced epithelial ovarian cancer: A SEER-MHOS study. 
  • Presence and Number of Lymph Node Metastases Are Associated With Compromised Survival for Patients Younger Than Age 45 Years With Papillary Thyroid Cancer. 
  • Primary Cancer vs Competing Causes of Death in Survivors of Head and Neck Cancer. 
  • Primary brain and other central nervous system tumors in Appalachia: regional differences in incidence, mortality, and survival. 
  • Primary pancreatic lymphoma: a population-based analysis using the SEER program. 
  • Product liability forecasting for asbestos-related personal injury claims: a multidisciplinary approach. 
  • Progestin and estrogen potency of combination oral contraceptives and endometrial cancer risk. 
  • Prognostic factors and outcomes after definitive treatment of female urethral cancer: a population-based analysis. 
  • Projecting Survival in Papillary Thyroid Cancer: A Comparison of the Seventh and Eighth Editions of the American Joint Commission on Cancer/Union for International Cancer Control Staging Systems in Two Contemporary National Patient Cohorts. 
  • Prostate cancer disparities in Hispanics by country of origin: a nationwide population-based analysis. 
  • Prostate cancer screening. Why the controversy? 
  • Protecting Confidentiality in Cancer Registry Data With Geographic Identifiers. 
  • Quantifying the Dynamics of Field Cancerization in Tobacco-Related Head and Neck Cancer: A Multiscale Modeling Approach. 
  • Race and sex disparities in long-term survival of oral and oropharyngeal cancer in the United States. 
  • Race/ethnicity and the intensity of medical monitoring under 'watchful waiting' for prostate cancer. 
  • Race/ethnicity and the receipt of watchful waiting for the initial management of prostate cancer. 
  • Racial Differences in Treatment and Survival among Veterans and Non-Veterans with Stage I NSCLC: An Evaluation of Veterans Affairs and SEER-Medicare Populations. 
  • Racial differences in patterns of treatment among men diagnosed with de novo advanced prostate cancer: A SEER-Medicare investigation. 
  • Racial differences in prostate cancer risk remain among US servicemen with equal access to care. 
  • Racial disparities in cancer care in the Veterans Affairs health care system and the role of site of care. 
  • Racial disparities in individual breast cancer outcomes by hormone-receptor subtype, area-level socio-economic status and healthcare resources. 
  • Racial disparities in squamous cell carcinoma of the oral tongue among women: a SEER data analysis. 
  • Racial, Ethnic, and Socioeconomic Disparities in Retinoblastoma Enucleation: A Population-Based Study, SEER 18 2000-2014. 
  • Racial/ethnic disparities in de novo metastases sites and survival outcomes for patients with primary breast, colorectal, and prostate cancer. 
  • Racial/ethnic disparities in ovarian cancer research. 
  • Racial/ethnic disparities in the treatment of localized/regional prostate cancer. 
  • Reducing bias in cancer research: application of propensity score matching. 
  • Reducing ovarian cancer mortality through screening: Is it possible, and can we afford it? 
  • Representativeness of participants in the cancer care outcomes research and surveillance consortium relative to the surveillance, epidemiology, and end results program. 
  • Resource Use in the Last Year of Life Among Patients Who Died With Versus of Prostate Cancer. 
  • Risk of Prostate Cancer Associated With Familial and Hereditary Cancer Syndromes. 
  • Risk of second primary cancers among survivors of gynecological cancers. 
  • Risk of second primary cancers in individuals diagnosed with index smoking- and non-smoking- related cancers. 
  • Risk of subsequent malignant neoplasms after an index potentially-human papillomavirus (HPV)-associated cancers. 
  • Rural health disparities in melanoma staging and prognostic outcomes in Iowa. 
  • Sentinel lymph node biopsy is a prognostic measure in pediatric melanoma. 
  • Shared-patient physician networks and their impact on the uptake of genomic testing in breast cancer. 
  • Short-term costs associated with primary prophylactic G-CSF use during chemotherapy. 
  • Simultaneous medullary and differentiated thyroid cancer: a population-level analysis of an increasingly common entity. 
  • Socioeconomic Status in Relation to the Risk of Ovarian Cancer in African-American Women: A Population-Based Case-Control Study. 
  • Solid malignancies among etanercept-treated patients with granulomatosis with polyangiitis (Wegener's): long-term followup of a multicenter longitudinal cohort. 
  • Studying cancer in minorities: a look at the numbers. 
  • Studying health histories of cancer: a new model connecting cancer incidence and survival. 
  • Suicide risk among cancer survivors: Head and neck versus other cancers. 
  • Surgical staging for endometrial cancer in the elderly - is there a role for lymphadenectomy? 
  • Surveillance, Epidemiology, and End Results (SEER) database analysis of microcystic adnexal carcinoma (sclerosing sweat duct carcinoma) of the skin. 
  • Survival differences between patients with scalp or neck melanoma and those with melanoma of other sites in the Surveillance, Epidemiology, and End Results (SEER) program. 
  • Survival differences in nasopharyngeal carcinoma among racial and ethnic minority groups in the United States: A retrospective cohort study. 
  • Survival of patients undergoing cytoreductive surgery for metastatic renal cell carcinoma in the targeted-therapy era. 
  • Survivors of childhood cancer in the United States: prevalence and burden of morbidity. 
  • System-Level Health-Care Integration and the Costs of Cancer Care Across the Disease Continuum. 
  • T1a Versus T1b Differentiated Thyroid Cancers: Do We Need to Make the Distinction? 
  • The Epidemiology, Staging and Outcomes of Sarcomatoid Hepatocellular Carcinoma: A SEER Population Analysis. 
  • The Influence of Marital Status on Contemporary Patterns of Postmastectomy Breast Reconstruction. 
  • The association of pharmacy fill synchronization with breast cancer endocrine therapy adherence. 
  • The characteristics of bladder cancer after radiotherapy for prostate cancer. 
  • The effect of physician characteristics and their practice environment on surgical referral patterns for early-stage breast cancer in Iowa. 
  • The effects of cancer and racial disparities in health-related quality of life among older Americans: a case-control, population-based study. 
  • The epidemiology of central and extraventricular neurocytoma in the United States between 2006 and 2014. 
  • The health burden and economic costs of cutaneous melanoma mortality by race/ethnicity-United States, 2000 to 2006. 
  • The influence of radiation modality and lymph node dissection on survival in early-stage endometrial cancer. 
  • The use of adjuvant radiotherapy in elderly patients with early-stage breast cancer: changes in practice patterns after publication of Cancer and Leukemia Group B 9343. 
  • Time trends of incidence of age-associated diseases in the US elderly population: Medicare-based analysis. 
  • Time-varying survival effects for squamous cell carcinomas at oropharyngeal and nonoropharyngeal head and neck sites in the United States, 1973-2015. 
  • Treatment modalities for T1N0 esophageal cancers: a comparative analysis of local therapy versus surgical resection. 
  • Treatment patterns for prostate cancer: comparison of Medicare claims data to medical record review. 
  • Trends and appropriateness of perioperative chemotherapy for muscle-invasive bladder cancer. 
  • Trends and outcomes in the use of surgery and radiation for the treatment of locally advanced esophageal cancer: a propensity score adjusted analysis of the surveillance, epidemiology, and end results registry from 1998 to 2008. 
  • Trends in Insurance Status Among Patients Diagnosed With Cancer Before and After Implementation of the Affordable Care Act. 
  • Trends in Treatment Patterns and Outcomes for Ductal Carcinoma In Situ. 
  • Trends in central nervous system tumor incidence relative to other common cancers in adults, adolescents, and children in the United States, 2000 to 2010. 
  • Trends in the incidence rates of nasopharyngeal carcinoma among Chinese Americans living in Los Angeles County and the San Francisco metropolitan area, 1992-2002. 
  • Trends in the outcomes for patients with limited stage small cell lung cancer: An analysis of the Surveillance, Epidemiology, and End Results database. 
  • Trends in the risk and burden of second primary malignancy among survivors of smoking-related cancers in the United States. 
  • United States Population-Based Estimates of Patient-Reported Outcomes Measurement Information System Symptom and Functional Status Reference Values for Individuals With Cancer. 
  • Urinary incontinence and health-related quality of life among older Americans with and without cancer: a cross-sectional study. 
  • Use of nephron sparing surgery and impact on survival in children with Wilms tumor: a SEER analysis. 
  • Use of patient registries and administrative datasets for the study of pediatric cancer. 
  • Validation of a breast cancer risk prediction model developed for Black women. 
  • Variation in Physician-Specific Episode Payments for Major Cancer Surgery and Implications for the Merit-Based Incentive Program. 
  • Variations in use of PET among Medicare beneficiaries with non-small cell lung cancer, 1998-2007. 
  • Vestibular schwannomas in the modern era: epidemiology, treatment trends, and disparities in management. 
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  Keywords of People

  • Allen, Nancy Bates, Professor Emeritus of Medicine, Medicine, Rheumatology and Immunology
  • Berchuck, Andrew, James M. Ingram Distinguished Professor of Gynecologic Oncology, Obstetrics and Gynecology, Gynecologic Oncology
  • Ostrom, Quinn, Assistant Professor in Neurosurgery, Neurosurgery, Neuro-Oncology