Drug Resistance, Multiple
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Subject Areas on Research
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A Phase II trial of gemcitabine and mitoxantrone for patients with acute myeloid leukemia in first relapse.
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A prospective observational study of the effect of penicillin skin testing on antibiotic use in the intensive care unit.
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A structure-based mechanism for drug binding by multidrug transporters.
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ABCB1 (MDR1) polymorphisms and ovarian cancer progression and survival: a comprehensive analysis from the Ovarian Cancer Association Consortium and The Cancer Genome Atlas.
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Ascites Increases Expression/Function of Multidrug Resistance Proteins in Ovarian Cancer Cells.
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Can prenylcysteines be exploited as ligands for mammalian multidrug-resistance transporters?
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Characterization of prenylcysteines that interact with P-glycoprotein and inhibit drug transport in tumor cells.
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Clinical Outcomes and Healthcare Utilization Related to Multidrug-Resistant Gram-Negative Infections in Community Hospitals.
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Competition of hydrophobic peptides, cytotoxic drugs, and chemosensitizers on a common P-glycoprotein pharmacophore as revealed by its ATPase activity.
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Crystal structure of MtaN, a global multidrug transporter gene activator.
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Crystal structures of QacR-diamidine complexes reveal additional multidrug-binding modes and a novel mechanism of drug charge neutralization.
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Direct allelic variation scanning of the yeast genome.
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Dose escalation studies of cytarabine, daunorubicin, and etoposide with and without multidrug resistance modulation with PSC-833 in untreated adults with acute myeloid leukemia younger than 60 years: final induction results of Cancer and Leukemia Group B Study 9621.
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Dual action antifungal small molecule modulates multidrug efflux and TOR signaling.
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Emerging options for treatment of invasive, multidrug-resistant Staphylococcus aureus infections.
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Evaluation of in vitro chemoresponse profiles in women with Type I and Type II epithelial ovarian cancers: An observational study ancillary analysis.
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Functional expression of the multidrug resistance-associated protein in the yeast Saccharomyces cerevisiae.
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High-affinity inhibitors of dihydrofolate reductase: antimicrobial and anticancer activities of 7,8-dialkyl-1,3-diaminopyrrolo[3,2-f]quinazolines with small molecular size.
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Imaging drug resistance with radiolabeled molecules.
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Immunomodulator effect of picroliv and its potential in treatment against resistant Plasmodium yoelii (MDR) infection in mice.
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Immunosuppressant target protein FKBP12 is required for P-glycoprotein function in yeast.
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Incidence of invasive salmonella disease in sub-Saharan Africa: a multicentre population-based surveillance study.
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Infections caused by multidrug resistant organisms are not associated with overall, all-cause mortality in the surgical intensive care unit: the 20,000 foot view.
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Infections in patients with cystic fibrosis following lung transplantation.
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Intrinsic Xenobiotic Resistance of the Intestinal Stem Cell Niche.
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Low-dose interleukin-2 immunotherapy does not improve outcome of patients age 60 years and older with acute myeloid leukemia in first complete remission: Cancer and Leukemia Group B Study 9720.
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Lysosomal accumulation of drugs in drug-sensitive MES-SA but not multidrug-resistant MES-SA/Dx5 uterine sarcoma cells.
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Modulating protein kinase C (PKC) to increase the efficacy of chemotherapy: stepping into darkness.
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Multidrug resistance in ocular melanoma.
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Overexpression of cell surface cytokeratin 8 in multidrug-resistant MCF-7/MX cells enhances cell adhesion to the extracellular matrix.
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P-glycoprotein mediated resistance to 5'-nor-anhydro-vinblastine (Navelbine).
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Phase 3 study of the multidrug resistance modulator PSC-833 in previously untreated patients 60 years of age and older with acute myeloid leukemia: Cancer and Leukemia Group B Study 9720.
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Point-of-prescription interventions to improve antimicrobial stewardship.
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Prevalence and risk factors for Enterobacteriaceae in patients hospitalized with community-acquired pneumonia.
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Prevalent mutator genotype identified in fungal pathogen Candida glabrata promotes multi-drug resistance.
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Role for c-jun N-terminal kinase in treatment-refractory acute myeloid leukemia (AML): signaling to multidrug-efflux and hyperproliferation.
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Sequential phase II Southwest Oncology Group studies (S0112 and S0301) of daunorubicin and cytarabine by continuous infusion, without and with ciclosporin, in older patients with previously untreated acute myeloid leukaemia.
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Status of the Prevention of Multidrug-Resistant Organisms in International Settings: A Survey of the Society for Healthcare Epidemiology of America Research Network.
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The future of therapy for childhood rhabdomyosarcoma: clues from molecular biology.
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The staphylococcal QacR multidrug regulator binds a correctly spaced operator as a pair of dimers.
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The structural mechanism for transcription activation by MerR family member multidrug transporter activation, N terminus.
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Uncovering scaling laws to infer multidrug response of resistant microbes and cancer cells.
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Vertical transmission of multidrug-resistant human immunodeficiency virus type 1 (HIV-1) and continued evolution of drug resistance in an HIV-1-infected infant.
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When should contact precautions and active surveillance be used to manage patients with multidrug-resistant enterobacteriaceae?
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[Epidemiology of chemoresistant Plasmodium falciparum].
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kdr-Type resistance in insects with special reference to the German cockroach, Blattella germanica.
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Keywords of People
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Barker, Piers Christopher Andrew,
Professor of Pediatrics,
Pediatrics, Cardiology
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Berchuck, Andrew,
James M. Ingram Distinguished Professor of Gynecologic Oncology,
Obstetrics and Gynecology, Gynecologic Oncology
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Pasquale, Dana Kristine,
Assistant Professor in Population Health Sciences,
Population Health Sciences