Tropism
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Subject Areas on Research
- Chemokine (C-C motif) receptor 5-using envelopes predominate in dual/mixed-tropic HIV from the plasma of drug-naive individuals.
- Distinctive gene transduction efficiencies of commonly used viral vectors in the retina.
- Dual tropism of HIV-1 envelopes derived from renal tubular epithelial cells of patients with HIV-associated nephropathy.
- Genetically and epidemiologically related "non-syncytium-inducing" isolates of HIV-1 display heterogeneous growth patterns in macrophages.
- HIV-1 fitness and macrophages.
- Molecular basis for cell tropism of CXCR4-dependent human immunodeficiency virus type 1 isolates.
- Molecular basis for the enterocyte tropism exhibited by Salmonella typhimurium type 1 fimbriae.
- Novel Strategy To Adapt Simian-Human Immunodeficiency Virus E1 Carrying env from an RV144 Volunteer to Rhesus Macaques: Coreceptor Switch and Final Recovery of a Pathogenic Virus with Exclusive R5 Tropism.
- Systemic gene transfer to skeletal muscle using reengineered AAV vectors.
- Virologic failure in first-line human immunodeficiency virus therapy with a CCR5 entry inhibitor, aplaviroc, plus a fixed-dose combination of lamivudine-zidovudine: nucleoside reverse transcriptase inhibitor resistance regardless of envelope tropism.
- Virologic failure in therapy-naive subjects on aplaviroc plus lopinavir-ritonavir: detection of aplaviroc resistance requires clonal analysis of envelope.