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Subject Areas on Research
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A 13-week, randomized double-blind, placebo-controlled, cross-over trial of ziprasidone in bipolar spectrum disorder.
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A Bayesian approach on sample size calculation for comparing means.
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A Crossover Design for Comparative Efficacy: A 36-Week Randomized Trial of Bevacizumab and Ranibizumab for Diabetic Macular Edema.
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A Double-Blinded, Randomized, Placebo-Controlled Trial to Evaluate Efficacy, Safety, and Tolerability of Single Doses of Tirasemtiv in Patients with Acetylcholine Receptor-Binding Antibody-Positive Myasthenia Gravis.
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A Phase I, Open-Label, Single-Dose Safety, Pharmacokinetic, and Tolerability Study of the Sumatriptan Iontophoretic Transdermal System in Adolescent Migraine Patients.
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A Randomized Dose Escalation Study of Intravenous Baclofen in Healthy Volunteers: Clinical Tolerance and Pharmacokinetics.
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A Randomized Phase II Crossover Study of Imatinib or Rituximab for Cutaneous Sclerosis after Hematopoietic Cell Transplantation.
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A comparison of once-daily extended-release methylphenidate formulations in children with attention-deficit/hyperactivity disorder in the laboratory school (the Comacs Study).
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A comparison of studies on the effects of controlled exposure to fine, coarse and ultrafine ambient particulate matter from a single location.
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A comparison of the case-control and case-crossover designs for estimating medical costs of nonfatal fall-related injuries among older Americans.
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A comparison of two oral ketamine-diazepam regimens for the sedation of anxious pediatric dental patients.
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A comparison of ultrasound-guided and landmark-based approaches to saphenous nerve blockade: a prospective, controlled, blinded, crossover trial.
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A controlled trial of acute effects of human exposure to traffic particles on pulmonary oxidative stress and heart rate variability.
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A lipidomics analysis of the relationship between dietary fatty acid composition and insulin sensitivity in young adults.
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A mobile application improves therapy-adherence rates in elderly patients undergoing rehabilitation: A crossover design study comparing documentation via iPad with paper-based control.
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A note on sample size calculation for mean comparisons based on noncentral t-statistics.
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A note on sample size determination for bioequivalence studies with high-order crossover designs.
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A phase III extension trial with a 1-arm crossover from leuprolide to degarelix: comparison of gonadotropin-releasing hormone agonist and antagonist effect on prostate cancer.
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A pilot phase II randomized, cross-over, double-blinded, controlled efficacy study of octreotide versus hyoscine hydrobromide for control of noisy breathing at the end-of-life.
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A pilot study assessing the bioavailability and pharmacokinetics of diazepam after intranasal and intravenous administration in healthy volunteers.
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A pilot study of cerebral and haemodynamic physiological changes during sedation with dexmedetomidine or propofol in patients with acute brain injury.
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A prospective, randomized, double-blind comparison of bilateral and right unilateral electroconvulsive therapy at different stimulus intensities.
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A randomized comparison of EUS-guided FNA versus CT or US-guided FNA for the evaluation of pancreatic mass lesions.
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A randomized controlled trial of ganaxolone in posttraumatic stress disorder.
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A randomized crossover study comparing a novel needle guidance technology for simulated internal jugular vein cannulation.
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A randomized placebo-controlled double-blind study evaluating the time course of response to methylphenidate hydrochloride extended-release capsules in children with attention-deficit/hyperactivity disorder.
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A randomized trial of a 6-week course of celecoxib on proteinuria in diabetic kidney disease.
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A randomized, controlled study to assess the effect of silk-like textiles and high-absorbency adult incontinence briefs on pressure ulcer prevention.
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A randomized, crossover phase 1 study to assess the effects of formulation (capsule vs tablet) and meal consumption on the bioavailability of dovitinib (TKI258).
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A randomized, double-blind, crossover clinical trial of diclofenac plus misoprostol versus acetaminophen in patients with osteoarthritis of the hip or knee.
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A randomized, double-blind, placebo-controlled phase II study of eculizumab in patients with refractory generalized myasthenia gravis.
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A randomized, placebo-controlled trial of early eptifibatide for non-ST-segment elevation acute coronary syndromes.
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A single dose of live oral cholera vaccine CVD 103-HgR is safe and immunogenic in HIV-infected and HIV-noninfected adults in Mali.
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A small sample confidence interval approach to assess individual bioequivalence.
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Accelerometer-Measured Daily Activity in Heart Failure With Preserved Ejection Fraction: Clinical Correlates and Association With Standard Heart Failure Severity Indices.
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Acceptability of sodium-reduced research diets, including the Dietary Approaches To Stop Hypertension diet, among adults with prehypertension and stage 1 hypertension.
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Acute 5-HT reuptake blockade potentiates human amygdala reactivity.
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Acute neurocognitive response to methylphenidate among survivors of childhood cancer: a randomized, double-blind, cross-over trial.
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Adrenergic dysregulation and pain with and without acute beta-blockade in women with fibromyalgia and temporomandibular disorder.
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Age moderates the short-term effects of transdermal 17beta-estradiol on endothelium-dependent vascular function in postmenopausal women.
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Amiodarone or an implantable cardioverter-defibrillator for congestive heart failure.
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An evaluation of the efficacy and safety of eszopiclone over 12 months in patients with chronic primary insomnia.
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An exploratory study of the combined effects of orally administered methylphenidate and delta-9-tetrahydrocannabinol (THC) on cardiovascular function, subjective effects, and performance in healthy adults.
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Antidepressant response to electroconvulsive therapy is sustained after catecholamine depletion.
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Applications of TMS to therapy in psychiatry.
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Assessing acute systemic effects of an inhaled drug with serial echocardiography: a placebo-controlled comparison of inhaled and intravenous dihydroergotamine.
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Assessing bioequivalence and drug interchangeability.
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Assessing bioequivalence using genomic data.
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Assessing the effectiveness of 3 months day and night home closed-loop insulin delivery in adults with suboptimally controlled type 1 diabetes: a randomised crossover study protocol.
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Atrial fibrillation and quality of life after pacemaker implantation for sick sinus syndrome: data from the Mode Selection Trial (MOST).
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Baseline plasma GABA: its relationship to the adverse effects of acute lorazepam administration on cognition in the elderly.
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Behavioral interventions may prolong remission in patients with inflammatory bowel disease.
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Bevacizumab in colorectal cancer.
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Biobehavioral Responses of Preterm Infants to Conventional and Swaddled Tub Baths: A Randomized Crossover Trial.
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Bioequivalence review for drug interchangeability.
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Blinded Patient Preference for Morphine Compared to Placebo in the Setting of Chronic Refractory Breathlessness--An Exploratory Study.
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Branched-chain amino acid supplementation and indicators of muscle damage after endurance exercise.
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Bronchial reactivity of healthy subjects: 18-20 h postexposure to ozone.
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Caffeine affects cardiovascular and neuroendocrine activation at work and home.
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Caffeine deprivation affects vigilance performance and mood.
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Caffeine impairs glucose metabolism in type 2 diabetes.
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Caffeine increases ambulatory glucose and postprandial responses in coffee drinkers with type 2 diabetes.
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Caffeine raises blood pressure at work.
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Can we predict which patients with refractory dyspnea will respond to opioids?
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Changes in plantar loading based on shoe type and sex during a jump-landing task.
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Characterization of bilateral frontal lobe cerebral oxygen saturation in patients with mild traumatic brain injury.
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Childhood asthma clusters and response to therapy in clinical trials.
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Chronic transdermal nicotine patch treatment effects on cognitive performance in age-associated memory impairment.
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Clinical characteristics and outcomes after unplanned intraaortic balloon counterpulsation in the Counterpulsation to Reduce Infarct Size Pre-PCI Acute Myocardial Infarction trial.
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Clinical outcomes of remission induction therapy for severe antineutrophil cytoplasmic antibody-associated vasculitis.
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Closing the Loop in Adults, Children and Adolescents With Suboptimally Controlled Type 1 Diabetes Under Free Living Conditions: A Psychosocial Substudy.
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Cocaine use and the occurrence of panic attacks in the community: a case-crossover approach.
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Combination insulin and sulfonylurea therapy in insulin-requiring type 2 diabetes mellitus.
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Combined catecholamine and indoleamine depletion following response to ECT.
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Comparative effectiveness of low- and high-fidelity bronchoscopy simulation for training in conventional transbronchial needle aspiration and user preferences.
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Comparative pharmacokinetics of voriconazole administered orally as either crushed or whole tablets.
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Comparing diurnal and nocturnal effects of brinzolamide and timolol on intraocular pressure in patients receiving latanoprost monotherapy.
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Comparison in humans of the potency and pharmacokinetics of intravenously injected cocaethylene and cocaine.
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Comparison of Combined Endoscopic Ultrasonography and Endoscopic Secretin Testing With the Traditional Secretin Pancreatic Function Test in Patients With Suspected Chronic Pancreatitis: A Prospective Crossover Study.
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Comparison of Glucosamine Absorption After Administration of Oral Liquid, Chewable, and Tablet Formulations to Dogs.
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Comparison of an Electronic Glycemic Management System Versus Provider-Managed Subcutaneous Basal Bolus Insulin Therapy in the Hospital Setting.
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Comparison of morning vs bedtime administration of the combination of valsartan/amlodipine on nocturnal brachial and central blood pressure in patients with hypertension.
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Comparison of self-expanding and balloon-expandable stents for the reduction of restenosis.
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Comparison of the efficacy and safety of arformoterol 15 microg twice daily and arformoterol 30 microg once daily in COPD: a single-dose, multicenter, randomized, modified-blind, two-way crossover study.
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Comparison of transbronchial lung biopsy yield between standard forceps and electrocautery hot forceps in swine.
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Complete longitudinal analyses of the randomized, placebo-controlled, phase III trial of sunitinib in patients with gastrointestinal stromal tumor following imatinib failure.
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Controlled exposure to diesel exhaust causes increased nitrite in exhaled breath condensate among subjects with asthma.
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Coregulated approach to feeding preterm infants with lung disease: effects during feeding.
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Culturally-sensitive weight loss program produces significant reduction in weight, blood pressure, and cholesterol in eight weeks.
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DHEA metabolism to the neurosteroid androsterone: a possible mechanism of DHEA's antidepressant action.
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Day-and-Night Closed-Loop Insulin Delivery in a Broad Population of Pregnant Women With Type 1 Diabetes: A Randomized Controlled Crossover Trial.
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Determination of the appropriate sizes of oropharyngeal airways in adults: correlation with external facial measurements: A randomised crossover study.
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Dexmedetomidine pharmacodynamics: Part II: Crossover comparison of the analgesic effect of dexmedetomidine and remifentanil in healthy volunteers.
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Dexmedetomidine pharmacodynamics: part I: crossover comparison of the respiratory effects of dexmedetomidine and remifentanil in healthy volunteers.
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Dietary intake of palmitate and oleate has broad impact on systemic and tissue lipid profiles in humans.
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Dietary nitrate supplementation enhances exercise performance in peripheral arterial disease.
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Differential effects of high-dose magnetic seizure therapy and electroconvulsive shock on cognitive function.
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Differential neurophysiological effects of magnetic seizure therapy (MST) and electroconvulsive shock (ECS) in non-human primates.
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Directional atherectomy versus balloon angioplasty for coronary ostial and nonostial left anterior descending coronary artery lesions: results from a randomized multicenter trial. The CAVEAT-I investigators. Coronary Angioplasty Versus Excisional Atherectomy Trial.
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Dose-proportional and stereospecific pharmacokinetics of methylphenidate delivered using an osmotic, controlled-release oral delivery system.
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Double-Blind, Placebo-Controlled, Crossover Study of Armodafinil Treatment of Daytime Sleepiness Associated With Treated Nocturia.
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Drug-drug interaction studies of cardiovascular drugs involving P-glycoprotein, an efflux transporter, on the pharmacokinetics of edoxaban, an oral factor Xa inhibitor.
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EUR-1008 pancreatic enzyme replacement is safe and effective in patients with cystic fibrosis and pancreatic insufficiency.
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Effect of Inorganic Nitrite vs Placebo on Exercise Capacity Among Patients With Heart Failure With Preserved Ejection Fraction: The INDIE-HFpEF Randomized Clinical Trial.
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Effect of a high-fiber diet vs a fiber-supplemented diet on C-reactive protein level.
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Effect of a single dose of diazepam on balance measures in older people.
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Effect of an intervention standardization system on pediatric dosing and equipment size determination: a crossover trial involving simulated resuscitation events.
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Effect of beta2-adrenergic receptor polymorphism on response to longacting beta2 agonist in asthma (LARGE trial): a genotype-stratified, randomised, placebo-controlled, crossover trial.
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Effect of catechol-O-methyltransferase polymorphism on response to propranolol therapy in chronic musculoskeletal pain: a randomized, double-blind, placebo-controlled, crossover pilot study.
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Effect of citrus juice and SLCO2B1 genotype on the pharmacokinetics of montelukast.
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Effect of daily dosing duration of direct and indirect dopamine receptor agonists: cocaine cross-tolerance following chronic regimens.
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Effect of duloxetine on pain, function, and quality of life among patients with chemotherapy-induced painful peripheral neuropathy: a randomized clinical trial.
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Effect of glaucoma medications on 24-hour intraocular pressure-related patterns using a contact lens sensor.
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Effect of hawthorn standardized extract on flow mediated dilation in prehypertensive and mildly hypertensive adults: a randomized, controlled cross-over trial.
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Effect of isosorbide mononitrate on the human optic nerve and choroidal circulations.
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Effect of ketoconazole on the pharmacokinetic profile of buprenorphine following administration of a once-weekly buprenorphine transdermal system.
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Effect of low versus high dialysate sodium concentration on blood pressure and endothelial-derived vasoregulators during hemodialysis: a randomized crossover study.
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Effect of low vs. high dietary sodium on blood pressure levels in a normotensive Indo-Asian population.
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Effect of phenylephrine and ephedrine bolus treatment on cerebral oxygenation in anaesthetized patients.
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Effect of predicted low suspend pump treatment on improving glycaemic control and quality of sleep in children with type 1 diabetes and their caregivers: the QUEST randomized crossover study.
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Effect of simultaneous didanosine administration on itraconazole absorption in healthy volunteers.
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Effect of telcagepant on spontaneous ischemia in cardiovascular patients in a randomized study.
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Effect of the S-nitrosoglutathione reductase inhibitor N6022 on bronchial hyperreactivity in asthma.
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Effect of the bile acid sequestrant colesevelam on the pharmacokinetics of pioglitazone, repaglinide, estrogen estradiol, norethindrone, levothyroxine, and glyburide.
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Effect of varying contrast material iodine concentration and injection technique on the conspicuity of hepatocellular carcinoma during 64-section MDCT of patients with cirrhosis.
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Effect of virtual reality on time perception in patients receiving chemotherapy.
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Effectiveness of clozapine versus olanzapine, quetiapine, and risperidone in patients with chronic schizophrenia who did not respond to prior atypical antipsychotic treatment.
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Effectiveness of olanzapine, quetiapine, risperidone, and ziprasidone in patients with chronic schizophrenia following discontinuation of a previous atypical antipsychotic.
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Effectiveness of targeted enhanced terminal room disinfection on hospital-wide acquisition and infection with multidrug-resistant organisms and Clostridium difficile: a secondary analysis of a multicentre cluster randomised controlled trial with crossover design (BETR Disinfection).
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Effects of a 1:1 inspiratory to expiratory ratio on respiratory mechanics and oxygenation during one-lung ventilation in patients with low diffusion capacity of lung for carbon monoxide: a crossover study.
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Effects of blackcurrant anthocyanin intake on peripheral muscle circulation during typing work in humans.
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Effects of concurrent use of an ankle support with a laterally wedged insole for medial knee osteoarthritis.
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Effects of lisdexamfetamine dimesylate treatment for ADHD on growth.
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Effects of low-dose morphine on perceived sleep quality in patients with refractory breathlessness: A hypothesis generating study.
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Effects of recruitment maneuvers in patients with acute lung injury and acute respiratory distress syndrome ventilated with high positive end-expiratory pressure.
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Effects of spinal manipulation on trunk proprioception in subjects with chronic low back pain during symptom remission.
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Effects on blood pressure of reduced dietary sodium and the Dietary Approaches to Stop Hypertension (DASH) diet. DASH-Sodium Collaborative Research Group.
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Efficacy and Tolerability of Evolocumab vs Ezetimibe in Patients With Muscle-Related Statin Intolerance: The GAUSS-3 Randomized Clinical Trial.
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Efficacy and safety of enoxaparin compared with unfractionated heparin in high-risk patients with non-ST-segment elevation acute coronary syndrome undergoing percutaneous coronary intervention in the Superior Yield of the New Strategy of Enoxaparin, Revascularization and Glycoprotein IIb/IIIa Inhibitors (SYNERGY) trial.
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Efficacy and safety of immediate-release methylphenidate treatment for preschoolers with ADHD.
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Efficacy of Flecainide in the Treatment of Catecholaminergic Polymorphic Ventricular Tachycardia: A Randomized Clinical Trial.
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Efficacy of olanzapine and risperidone in schizophrenia: a randomized double-blind crossover design.
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Efficacy, safety and survival with ruxolitinib in patients with myelofibrosis: results of a median 2-year follow-up of COMFORT-I.
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Electrocardiographic safety of cangrelor, a new intravenous antiplatelet agent: a randomized, double-blind, placebo- and moxifloxacin-controlled thorough QT study.
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Emotional antecedents of hot flashes during daily life.
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Enhanced terminal room disinfection and acquisition and infection caused by multidrug-resistant organisms and Clostridium difficile (the Benefits of Enhanced Terminal Room Disinfection study): a cluster-randomised, multicentre, crossover study.
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Evaluating patient-reported outcome measurement comparability between paper and alternate versions, using the lung function questionnaire as an example.
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Evaluation of a scaling approach for the bioequivalence of highly variable drugs.
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Evaluation of dose-related effects of aspirin on platelet function: results from the Aspirin-Induced Platelet Effect (ASPECT) study.
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Evaluation of the pharmacokinetic drug interaction potential of tivantinib (ARQ 197) using cocktail probes in patients with advanced solid tumours.
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Everolimus with reduced tacrolimus improves renal function in de novo liver transplant recipients: a randomized controlled trial.
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Examining outlying subjects and outlying records in bioequivalence trials.
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Exenatide Protects Against Glucose- and Lipid-Induced Endothelial Dysfunction: Evidence for Direct Vasodilation Effect of GLP-1 Receptor Agonists in Humans.
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Experiences of closed-loop insulin delivery among pregnant women with Type 1 diabetes.
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Exposure to concentrated coarse air pollution particles causes mild cardiopulmonary effects in healthy young adults.
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Fibroblast growth factor 21 mediates specific glucagon actions.
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Final analysis of a randomised trial comparing pembrolizumab versus investigator-choice chemotherapy for ipilimumab-refractory advanced melanoma.
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First-in-man evaluation of 2 high-affinity PSMA-avid small molecules for imaging prostate cancer.
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Fludarabine compared with chlorambucil as primary therapy for chronic lymphocytic leukemia.
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Functional Incidental Training: applicability and feasibility in the Veterans Affairs nursing home patient population.
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Functional incidental training: a randomized, controlled, crossover trial in Veterans Affairs nursing homes.
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Glucose and lipid effects of the ileal apical sodium-dependent bile acid transporter inhibitor GSK2330672: double-blind randomized trials with type 2 diabetes subjects taking metformin.
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Glycoprotein IIb/IIIa Receptor Inhibitors in Combination With Vorapaxar, a Platelet Thrombin Receptor Antagonist, Among Patients With Non-ST-Segment Elevation Acute Coronary Syndromes (from the TRACER Trial).
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Group treatment improves trunk strength and psychological status in older women with vertebral fractures: results of a randomized, clinical trial.
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Gut hormone pharmacology of a novel GPR119 agonist (GSK1292263), metformin, and sitagliptin in type 2 diabetes mellitus: results from two randomized studies.
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Holding back the sea: the role for maintenance chemotherapy in metastatic breast cancer.
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Home Use of an Artificial Beta Cell in Type 1 Diabetes.
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Home use of closed-loop insulin delivery for overnight glucose control in adults with type 1 diabetes: a 4-week, multicentre, randomised crossover study.
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Human retinal hemodynamics following administration of 5-isosorbide mononitrate.
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Identification of provider characteristics influencing prescription of analgesics: a systematic literature review.
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Immune and clinical impact of Lactobacillus acidophilus on asthma.
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Impact of cinematic viewing on endothelial function.
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Impact of endovascular simulator training on vascular surgery as a career choice in medical students.
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Impact of tax and subsidy framed messages on high- and lower-sugar beverages sold in vending machines: a randomized crossover trial.
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Impairment and deportment responses to different methylphenidate doses in children with ADHD: the MTA titration trial.
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Improved gastrointestinal tolerance and palatability of didanosine in adults by the use of pediatric power formulation.
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Improvements in distal lung function correlate with asthma symptoms after treatment with oral montelukast.
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In-hospital costs of coronary stent implantation with and without eptifibatide (the ESPRIT Trial). Enhanced Suppression of the Platelet IIb/IIIa Receptor with Integrilin.
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Individual bioequivalence testing under 2x3 designs.
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Individual blood pressure responses to changes in salt intake: results from the DASH-Sodium trial.
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Influence of Amlodipine on Haemostatic Measurements during Clopidogrel Treatment in Patients with Coronary Artery Disease.
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Influence of crossover on mortality in a randomized study of revascularization in patients with systolic heart failure and coronary artery disease.
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Inhaled fentanyl aerosol in healthy volunteers: pharmacokinetics and pharmacodynamics.
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Intravenous Allogeneic Mesenchymal Stem Cells for Nonischemic Cardiomyopathy: Safety and Efficacy Results of a Phase II-A Randomized Trial.
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Isosorbide Mononitrate in Heart Failure with Preserved Ejection Fraction.
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Lack of effect of increased inspired oxygen concentrations on maximal exercise capacity or ventilation in stable heart failure.
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Lack of effect of ondansetron on the pharmacokinetics and analgesic effects of morphine and metabolites after single-dose morphine administration in healthy volunteers.
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Lack of food effect on single-dose pharmacokinetics of brivanib, and safety and efficacy following multiple doses in subjects with advanced or metastatic solid tumors.
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Lack of relapse with tryptophan depletion following successful treatment with ECT.
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Long-term tolerability and efficacy of degarelix: 5-year results from a phase III extension trial with a 1-arm crossover from leuprolide to degarelix.
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Luteal support with both estradiol and progesterone after clomiphene citrate stimulation for in vitro fertilization.
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Macronutrient Regulation of Ghrelin and Peptide YY in Pediatric Obesity and Prader-Willi Syndrome.
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Mecamylamine modifies the pharmacokinetics and reinforcing effects of alcohol.
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Mexiletine for symptoms and signs of myotonia in nondystrophic myotonia: a randomized controlled trial.
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Mode equivalence and acceptability of tablet computer-, interactive voice response system-, and paper-based administration of the U.S. National Cancer Institute's Patient-Reported Outcomes version of the Common Terminology Criteria for Adverse Events (PRO-CTCAE).
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Mometasone or Tiotropium in Mild Asthma with a Low Sputum Eosinophil Level.
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More Evidence for Non-P2Y12-Mediated Effects of Ticagrelor.
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Multicenter crossover comparison of the safety and efficacy of Intraglobin-F with Gamimune-N, Sandoglobulin, and Gammagard in patients with primary immunodeficiency diseases.
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Nanofiltered C1 inhibitor concentrate for treatment of hereditary angioedema.
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Near-infrared light therapy to attenuate strength loss after strenuous resistance exercise.
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Neuropsychological and psychiatric sequelae of pallidotomy for PD: clinical trial findings.
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Neutral effect on markers of heart failure, inflammation, endothelial activation and function, and vagal tone after high-dose HMG-CoA reductase inhibition in non-diabetic patients with non-ischemic cardiomyopathy and average low-density lipoprotein level.
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Nicotine pharmacokinetics and subjective effects of three potential reduced exposure products, moist snuff and nicotine lozenge.
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Nonparametric tests for evaluation of biosimilarity in variability of follow-on biologics.
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Novel dosing regimen of eptifibatide in planned coronary stent implantation (ESPRIT): a randomised, placebo-controlled trial.
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Olanzapine in refractory schizophrenia after failure of typical or atypical antipsychotic treatment: an open-label switch study.
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On hybrid parallel-crossover designs for assessing drug interchangeability of biosimilar products.
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On power and sample size calculation for QT studies with recording replicates at given time point.
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On sample size calculation based on odds ratio in clinical trials.
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On sample size calculation in bioequivalence trials.
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On statistical analysis for placebo-challenging designs in clinical trials.
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On statistical power for average bioequivalence testing under replicated crossover designs.
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On the assessment of dose proportionality: a comparison of two slope approaches.
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Outcomes following bail-out abciximab administration during primary intervention in acute myocardial infarction (The CADILLAC Trial).
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Outcomes in elderly patients with acute coronary syndromes randomized to enoxaparin vs. unfractionated heparin: results from the SYNERGY trial.
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Outcomes of bail-out stenting for suboptimal balloon angioplasty during primary intervention in acute myocardial infarction (The CADILLAC trial).
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Overall survival benefit with lapatinib in combination with trastuzumab for patients with human epidermal growth factor receptor 2-positive metastatic breast cancer: final results from the EGF104900 Study.
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Overview of registered studies in orthodontics: Evaluation of the ClinicalTrials.gov registry.
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Oxaprozin and piroxicam, nonsteroidal antiinflammatory drugs with long half-lives: effect of protein-binding differences on steady-state pharmacokinetics.
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Pain assessment in patients with fibromyalgia syndrome: a consideration of methods for clinical trials.
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Paper versus web-based administration of the Pelvic Floor Distress Inventory 20 and Pelvic Floor Impact Questionnaire 7.
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Patient preference in a crossover clinical trial of patients with osteoarthritis of the knee or hip: face validity of self-report questionnaire ratings.
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Patient-ventilator synchrony during pressure-targeted versus flow-targeted small tidal volume assisted ventilation.
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Patients with asthma demonstrate airway inflammation after exposure to concentrated ambient particulate matter.
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Pharmacodynamic efficacy and safety of adjunctive cilostazol loading to clopidogrel and aspirin loading: the results of the ACCEL-LOADING (Accelerated Platelet Inhibition by Cilostazol Loading) study.
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Pharmacodynamic evaluation of clopidogrel plus PA32540: the Spaced PA32540 With Clopidogrel Interaction Gauging (SPACING) study.
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Pharmacogenetics of methylphenidate response in preschoolers with ADHD.
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Pharmacokinetic and safety evaluation of SangCya vs Neoral or Sandimmune in stable renal transplant recipients.
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Pharmacokinetic comparison of two cyclosporine A formulations, SangCya (Sang-35) and Neoral, in stable adult liver transplant recipients.
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Pharmacokinetics and bioequivalence of a combined oral formulation of eniluracil, an inactivator of dihydropyrimidine dehydrogenase, and 5-fluorouracil in patients with advanced solid malignancies.
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Pharmacokinetics of low and maintenance dose valganciclovir in kidney transplant recipients.
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Pharmacokinetics of posaconazole administered orally or by nasogastric tube in healthy volunteers.
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Pharmacologic and sensorimotor components of satiation in cigarette smoking.
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Phase 2 and 3 clinical trial of oral bexarotene (Targretin capsules) for the treatment of refractory or persistent early-stage cutaneous T-cell lymphoma.
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Phase I pharmacokinetic studies evaluating single and multiple doses of oral GW572016, a dual EGFR-ErbB2 inhibitor, in healthy subjects.
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Phase II, randomized trial comparing bevacizumab plus fluorouracil (FU)/leucovorin (LV) with FU/LV alone in patients with metastatic colorectal cancer.
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Phosphodiesterase 5 inhibition improves beta-cell function in metabolic syndrome.
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Photobiomodulation delays the onset of skeletal muscle fatigue in a dose-dependent manner.
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Plantar loading during cutting while wearing a rigid carbon fiber insert.
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Plasma acylcarnitine profiling indicates increased fatty acid oxidation relative to tricarboxylic acid cycle capacity in young, healthy low birth weight men.
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Platelet function measured by VerifyNow identifies generalized high platelet reactivity in aspirin treated patients.
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Platelet glycoprotein IIb/IIIa integrin blockade with eptifibatide in coronary stent intervention: the ESPRIT trial: a randomized controlled trial.
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Prasugrel 5 mg in the very elderly attenuates platelet inhibition but maintains noninferiority to prasugrel 10 mg in nonelderly patients: the GENERATIONS trial, a pharmacodynamic and pharmacokinetic study in stable coronary artery disease patients.
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Predicting methylphenidate response in long-term survivors of childhood cancer: a randomized, double-blind, placebo-controlled, crossover trial.
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Predictors and Outcomes of Crossover to Surgery from Physical Therapy for Meniscal Tear and Osteoarthritis: A Randomized Trial Comparing Physical Therapy and Surgery.
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Predictors of response to tiotropium versus salmeterol in asthmatic adults.
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Psychosocial aspects of closed- and open-loop insulin delivery: closing the loop in adults with Type 1 diabetes in the home setting.
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Pulmonary delivery of nicotine pyruvate: sensory and pharmacokinetic characteristics.
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Pulmonary function, bronchial reactivity, and epithelial permeability are response phenotypes to ozone and develop differentially in healthy humans.
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QMG and MG-ADL correlations: Study of eculizumab treatment of myasthenia gravis.
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Quality-adjusted survival in a crossover trial of letrozole versus tamoxifen in postmenopausal women with advanced breast cancer.
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Randomised, double blind, placebo controlled crossover trial of sustained release morphine for the management of refractory dyspnoea.
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Randomized controlled trial of azacitidine in patients with the myelodysplastic syndrome: a study of the cancer and leukemia group B.
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Randomized crossover trial comparing the eZ.on plastic condom and a latex condom.
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Randomized placebo-controlled crossover trial of tadalafil in Raynaud's phenomenon secondary to systemic sclerosis.
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Randomized trial of lacosamide versus fosphenytoin for nonconvulsive seizures.
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Randomized, controlled study of telcagepant in patients with migraine and coronary artery disease.
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Randomized, double-blind, placebo-controlled, crossover study of sertraline (Zoloft) for the treatment of hot flashes in women with early stage breast cancer taking tamoxifen.
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Randomized, multicenter trial of inhaled nitric oxide and high-frequency oscillatory ventilation in severe, persistent pulmonary hypertension of the newborn.
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Ranibizumab for treatment of neovascular age-related macular degeneration: a phase I/II multicenter, controlled, multidose study.
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Rationale and design of a randomized controlled trial of allogeneic mesenchymal stem cells in patients with nonischemic cardiomyopathy.
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Reach out to enhance wellness home-based diet-exercise intervention promotes reproducible and sustainable long-term improvements in health behaviors, body weight, and physical functioning in older, overweight/obese cancer survivors.
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Recombinant glucagon-like peptide-1 (7-36 amide) lowers fasting serum glucose in a broad spectrum of patients with type 2 diabetes.
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Remediation of sleep-deprivation-induced working memory impairment with fMRI-guided transcranial magnetic stimulation.
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Repetitive transcranial magnetic stimulation to SMA worsens complex movements in Parkinson's disease.
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Respiratory and cardiovascular responses to walking down a traffic-polluted road compared with walking in a traffic-free area in participants aged 60 years and older with chronic lung or heart disease and age-matched healthy controls: a randomised, crossover study.
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Respiratory effects of exposure to diesel traffic in persons with asthma.
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Response to ticagrelor in clopidogrel nonresponders and responders and effect of switching therapies: the RESPOND study.
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Results from the IQ-CSRC prospective study support replacement of the thorough QT study by QT assessment in the early clinical phase.
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Ropinirole 24-hour prolonged release and ropinirole immediate release in early Parkinson's disease: a randomized, double-blind, non-inferiority crossover study.
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Safety and efficacy of abciximab combined with dalteparin in treatment of acute coronary syndromes.
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Safety and feasibility of magnetic seizure therapy (MST) in major depression: randomized within-subject comparison with electroconvulsive therapy.
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Safety of nifedipine in patients with hypertension: a meta-analysis.
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Sex-specific effects of cigarette mentholation on brain nicotine accumulation and smoking behavior.
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Sexual activity and cardiovascular disease: a scientific statement from the American Heart Association.
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Short-Term Risk of Serious Fall Injuries in Older Adults Initiating and Intensifying Treatment With Antihypertensive Medication.
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Short-term efficacy of methylphenidate: a randomized, double-blind, placebo-controlled trial among survivors of childhood cancer.
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Sleep and residual sedation after administration of zaleplon, zolpidem, and placebo during experimental middle-of-the-night awakening.
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Soybean isoflavones improve cardiovascular risk factors without affecting the reproductive system of peripubertal rhesus monkeys.
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Spaced administration of PA32540 and clopidogrel results in greater platelet inhibition than synchronous administration of enteric-coated aspirin and enteric-coated omeprazole and clopidogrel.
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Statistical assessment of QT/QTc prolongation based on maximum of correlated normal random variables.
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Statistical methods for assessing interchangeability of biosimilars.
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Statistical methods for two-sequence three-period cross-over designs with incomplete data.
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Steady-state bioavailability of extended-release methylphenidate (MPH-MLR) capsule vs. immediate-release methylphenidate tablets in healthy adult volunteers.
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Step-Up Therapy in Black Children and Adults with Poorly Controlled Asthma.
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Substituting dietary monounsaturated fat for saturated fat is associated with increased daily physical activity and resting energy expenditure and with changes in mood.
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Systemic and cerebral hemodynamic responses to the noncompetitive N-methyl-D-aspartate (NMDA) antagonist CNS 1102.
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Temporo-parietal junction stimulation in the treatment of depersonalization disorder.
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Testosterone rapidly increases neural reactivity to threat in healthy men: a novel two-step pharmacological challenge paradigm.
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Tests for inter-subject and total variabilities under crossover designs.
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The Antimicrobial Scrub Contamination and Transmission (ASCOT) Trial: A Three-Arm, Blinded, Randomized Controlled Trial With Crossover Design to Determine the Efficacy of Antimicrobial-Impregnated Scrubs in Preventing Healthcare Provider Contamination.
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The DASH diet enhances the blood pressure response to losartan in hypertensive patients.
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The Effect of Paging Reminders on Fellowship Conference Attendance: A Multi-Program Randomized Crossover Study.
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The Efficacy and Safety of Evekeo, Racemic Amphetamine Sulfate, for Treatment of Attention-Deficit/Hyperactivity Disorder Symptoms: A Multicenter, Dose-Optimized, Double-Blind, Randomized, Placebo-Controlled Crossover Laboratory Classroom Study.
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The PESSRI study: symptom relief outcomes of a randomized crossover trial of the ring and Gellhorn pessaries.
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The control group dilemma in clinical research: applications for psychosocial and behavioral medicine trials.
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The costs of fatal and non-fatal falls among older adults.
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The effect of aprepitant and race on the pharmacokinetics of cyclophosphamide in breast cancer patients.
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The effect of aspirin dosing on platelet function in diabetic and nondiabetic patients: an analysis from the aspirin-induced platelet effect (ASPECT) study.
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The effect of body inclination during prone positioning on intraocular pressure in awake volunteers: a comparison of two operating tables.
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The effect of formulation and food consumption on the bioavailability of dovitinib (TKI258) in patients with advanced solid tumors.
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The effect of salmeterol on nocturnal symptoms, airway function, and inflammation in asthma.
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The effect of ticagrelor versus clopidogrel on high on-treatment platelet reactivity: combined analysis of the ONSET/OFFSET and RESPOND studies.
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The effects of smoking on levels of endothelial progenitor cells and microparticles in the blood of healthy volunteers.
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The electromechanical substrate for response to cardiac resynchronization therapy in patients with right bundle branch block.
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The impact of alcohol among injury patients in Moshi, Tanzania: a nested case-crossover study.
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The impact of heat exposure on reduced gestational age in pregnant women in North Carolina, 2011-2015.
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The impact of intraocular pressure reduction on retinal ganglion cell function measured using pattern electroretinogram in eyes receiving latanoprost 0.005% versus placebo.
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The impact of outlying subjects on decision of bioequivalence.
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The impact of postrandomization crossover of therapy in acute coronary syndromes care.
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The independently fractal nature of respiration and heart rate during exercise under normobaric and hyperbaric conditions.
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The influence of red wine or white wine intake on platelet function and viscoelastic property of blood in volunteers.
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The influence of smoking status on the pharmacokinetics and pharmacodynamics of clopidogrel and prasugrel: the PARADOX study.
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The sleep effects of lurasidone: a placebo-controlled cross-over study using a 4-h phase-advance model of transient insomnia.
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The steroid metabolome in women with premenstrual dysphoric disorder during GnRH agonist-induced ovarian suppression: effects of estradiol and progesterone addback.
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The use of the case-crossover design in studying illicit drug use.
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Theophylline's effect on neutrophil function and the late asthmatic response.
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Theophylline: potential antiinflammatory effects in nocturnal asthma.
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Tiotropium bromide step-up therapy for adults with uncontrolled asthma.
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Topical versus oral carbonic anhydrase inhibitor therapy for pediatric glaucoma.
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Transcutaneous electrical nerve stimulation as an adjunct for controlling chemotherapy-induced nausea and vomiting in gynecologic oncology patients.
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Transdermal nicotine attenuates depression symptoms in nonsmokers: a double-blind, placebo-controlled trial.
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Transition from intravenous epoprostenol to intravenous treprostinil in pulmonary hypertension.
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Treatment crossovers did not affect randomized treatment comparisons in the Mode Selection Trial (MOST).
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Treatment of hereditary angioedema with a vapor-heated C1 inhibitor concentrate.
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Unsupervised home use of an overnight closed-loop system over 3-4 weeks: a pooled analysis of randomized controlled studies in adults and adolescents with type 1 diabetes.
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Use of regularly scheduled albuterol treatment in asthma: genotype-stratified, randomised, placebo-controlled cross-over trial.
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Use of vagal nerve stimulation as a treatment for refractory epilepsy in dogs.
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Usefulness of routine unfractionated heparin infusion following primary percutaneous coronary intervention for acute myocardial infarction in patients not receiving glycoprotein IIb/IIIa inhibitors.
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Usefulness of the VerifyNow P2Y12 assay to evaluate the antiplatelet effects of ticagrelor and clopidogrel therapies.
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Using observational data to estimate prognosis: an example using a coronary artery disease registry.
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Vaginal distribution of Replens and K-Y Jelly using three imaging techniques.
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Validation of alternate modes of administration of the lung function questionnaire (LFQ) in subjects with smoking history.
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Virtual reality as a distraction intervention for women receiving chemotherapy.
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Keywords of People
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Allen, Nancy Bates,
Professor of Medicine,
Medicine, Rheumatology and Immunology
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Gold, Deborah T.,
Professor in Psychiatry and Behavioral Sciences,
Psychology and Neuroscience
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Jowell, Paul Simon,
Professor of Medicine,
Medicine, Gastroenterology
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Wu, Li-Tzy,
Professor in Psychiatry and Behavioral Sciences,
Medicine, General Internal Medicine