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Subject Areas on Research
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28-day toxicology test: indenopyridine RTI 4587-056 in male Sprague-Dawley rats.
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A call for fuller reporting of toxicity test data
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A mechanism-based complementary screening approach for the amelioration and reversal of neurobehavioral teratogenicity.
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A tiered approach to systemic toxicity testing for agricultural chemical safety assessment.
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Acute neuroactive drug exposures alter locomotor activity in larval zebrafish.
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Adapting the medaka embryo assay to a high-throughput approach for developmental toxicity testing.
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Advancing the science of developmental neurotoxicity (DNT): testing for better safety evaluation.
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Advancing toxicology research using in vivo high throughput toxicology with small fish models.
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An adaptable mesocosm platform for performing integrated assessments of nanomaterial risk in complex environmental systems.
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An avian model for the reversal of neurobehavioral teratogenicity with neural stem cells.
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An expert-driven literature review of "negative" chemicals for developmental neurotoxicity (DNT) in vitro assay evaluation.
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Are quantum dots toxic? Exploring the discrepancy between cell culture and animal studies.
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Assessing the risks of manufactured nanomaterials.
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Atypical tubule hyperplasia and renal tubule tumors in conventional rats on 90-day toxicity studies.
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BDE 49 and developmental toxicity in zebrafish.
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Bacterial Growth Inhibition Screen (BGIS) identifies a loss-of-function mutant of the DEK oncogene, indicating DNA modulating activities of DEK in chromatin.
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Bacterial Growth Inhibition Screen (BGIS): harnessing recombinant protein toxicity for rapid and unbiased interrogation of protein function.
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Battery of neurobehavioral tests recommended to ATSDR: solvent-induced deficits in microelectronic workers.
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Biochemical approaches to studying neurotoxicity.
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Biotic and abiotic interactions in aquatic microcosms determine fate and toxicity of Ag nanoparticles: part 2-toxicity and Ag speciation.
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Brief embryonic strychnine exposure in zebrafish causes long-term adult behavioral impairment with indications of embryonic synaptic changes.
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Bronchial and bronchiolar fibrosis in rats exposed to 2,3-pentanedione vapors: implications for bronchiolitis obliterans in humans.
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Caenorhabditis elegans as a Model for Toxic Effects of Nanoparticles: Lethality, Growth, and Reproduction.
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Caenorhabditis elegans: an emerging model in biomedical and environmental toxicology.
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Characterizing sources of variability in zebrafish embryo screening protocols.
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Choice of vehicle affects pyraclostrobin toxicity in mice.
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Clinical Trial in a Dish: Personalized Stem Cell-Derived Cardiomyocyte Assay Compared With Clinical Trial Results for Two QT-Prolonging Drugs.
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Comparative toxicities of selected compounds to nauplii of Balanus amphitrite amphitrite Darwin and Artemia sp.
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Comparative toxicity of C60 aggregates toward mammalian cells: role of tetrahydrofuran (THF) decomposition.
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Continuing education course #3: current practices and future trends in neuropathology assessment for developmental neurotoxicity testing.
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Design considerations for an integrated microphysiological muscle tissue for drug and tissue toxicity testing.
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Determining the ecological impacts of organic contaminants in biosolids using a high-throughput colorimetric denitrification assay: a case study with antimicrobial agents.
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Development of a quantitative morphological assessment of toxicant-treated zebrafish larvae using brightfield imaging and high-content analysis.
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Developmental exposure to valproate and ethanol alters locomotor activity and retino-tectal projection area in zebrafish embryos.
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Developmental neurotoxic effects of chlorpyrifos on acetylcholine and serotonin pathways in an avian model.
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Discovery and ramifications of incidental Magnéli phase generation and release from industrial coal-burning.
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Does shaking alter the time of hatching in incubated medaka (Oryzias latipes) embryos?
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Effects of Toxic Leachate from Commercial Plastics on Larval Survival and Settlement of the Barnacle Amphibalanus amphitrite.
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Effects of immobilization restraint on Syrian golden hamsters.
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Effects of subchronic exposure to a complex mixture of persistent contaminants in male rats: systemic, immune, and reproductive effects.
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Evaluation of Maternal, Embryo, and Placental Effects in CD-1 Mice following Gestational Exposure to Perfluorooctanoic Acid (PFOA) or Hexafluoropropylene Oxide Dimer Acid (HFPO-DA or GenX).
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Expanding the test set: Chemicals with potential to disrupt mammalian brain development.
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Flow Cytometry for the Immunotoxicologist.
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Further assessment of an in vitro screen that may help identify organophosphorus pesticides that are more acutely toxic to the young.
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Generation and characterization of neurogenin1-GFP transgenic medaka with potential for rapid developmental neurotoxicity screening.
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High-throughput cardiac safety evaluation and multi-parameter arrhythmia profiling of cardiomyocytes using microelectrode arrays.
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Impact of strain type on detection of toxigenic Clostridium difficile: comparison of molecular diagnostic and enzyme immunoassay approaches.
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In vitro exposure systems and dosimetry assessment tools for inhaled tobacco products: Workshop proceedings, conclusions and paths forward for in vitro model use.
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Introduction to the special issue on emerging high throughput and complementary model screens for neurotoxicology.
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Is There a Space-Based Technology Solution to Problems with Preclinical Drug Toxicity Testing?
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Laboratory animal science issues in the design and conduct of studies with endocrine-active compounds.
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Larval biology of the crab Rhithropanopeus harrisii (Gould): a synthesis.
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Learning about cognition risk with the radial-arm maze in the developmental neurotoxicology battery.
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Life-cycle effects of single-walled carbon nanotubes (SWNTs) on an estuarine meiobenthic copepod.
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Methods to identify and characterize developmental neurotoxicity for human health risk assessment. III: pharmacokinetic and pharmacodynamic considerations.
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Nanomaterial categorization for assessing risk potential to facilitate regulatory decision-making.
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New Cembranolide Analogues from the Formosan Soft Coral Sinularia flexibilis and Their Cytotoxicity
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Reference compounds for alternative test methods to indicate developmental neurotoxicity (DNT) potential of chemicals: example lists and criteria for their selection and use.
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Repetitive Ozone Exposures and Evaluation of Pulmonary Inflammation and Remodeling in Diabetic Mouse Strains.
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Response to comment on "Determining the ecological impacts of organic contaminants in biosolids using a high-throughput colorimetric denitrification assay: a case study with antimicrobial agents".
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Screening for developmental neurotoxicity using PC12 cells: comparisons of organophosphates with a carbamate, an organochlorine, and divalent nickel.
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Sea urchin embryos and larvae as biosensors for neurotoxicants.
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Selected Resources for Pathology Evaluation of Nonhuman Primates in Nonclinical Safety Assessment.
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Selected contribution: a three-dimensional model for assessment of in vitro toxicity in balaena mysticetus renal tissue.
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Silver nanocolloids disrupt medaka embryogenesis through vital gene expressions.
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Silver nanoparticle toxicity to Atlantic killifish (Fundulus heteroclitus) and Caenorhabditis elegans: a comparison of mesocosm, microcosm, and conventional laboratory studies.
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Silver toxicity across salinity gradients: the role of dissolved silver chloride species (AgCl x ) in Atlantic killifish (Fundulus heteroclitus) and medaka (Oryzias latipes) early life-stage toxicity.
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Sublethal effects of pentachlorophenol in abalone (Haliotis rufescens) veliger larvae as measured by (31)P-NMR.
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Synergistic embryotoxicity of polycyclic aromatic hydrocarbon aryl hydrocarbon receptor agonists with cytochrome P4501A inhibitors in Fundulus heteroclitus.
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Taxonomic applicability of inflammatory cytokines in adverse outcome pathway (AOP) development.
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The fish embryo toxicity test as an animal alternative method in hazard and risk assessment and scientific research.
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The future of preclinical animal models in pharmaceutical discovery and development: a need to bring in cerebro to the in vivo discussions.
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The zebrafish embryo model in toxicology and teratology, September 2–3, 2010, Karlsruhe, Germany.
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Three-dimensional (3D) brain microphysiological system for organophosphates and neurochemical agent toxicity screening.
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Thyroid toxicity due to subchronic exposure to a complex mixture of 16 organochlorines, lead, and cadmium.
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Tissue-engineered blood vessels as promising tools for testing drug toxicity.
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Toxic actions of dinoseb in medaka (Oryzias latipes) embryos as determined by in vivo 31P NMR, HPLC-UV and 1H NMR metabolomics.
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Ultrasonic dispersion of nanoparticles for environmental, health and safety assessment--issues and recommendations.
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Ultraviolet photolysis of chlorpyrifos: developmental neurotoxicity modeled in PC12 cells.
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Unconventional oil and gas chemicals and wastewater-impacted water samples promote adipogenesis via PPARγ-dependent and independent mechanisms in 3T3-L1 cells.
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Use of medaka in toxicity testing.
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Use of short-term assays to evaluate the potential toxicity of two new biosoluble glasswool fibers.
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Zebrafish developmental screening of the ToxCast™ Phase I chemical library.
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Zebrafish model systems for developmental neurobehavioral toxicology.
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Zebrafish provide a sensitive model of persisting neurobehavioral effects of developmental chlorpyrifos exposure: comparison with nicotine and pilocarpine effects and relationship to dopamine deficits.
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Zebrafish: as an integrative model for twenty-first century toxicity testing.
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t⁴ workshop report. Nanotoxicology: "the end of the beginning" - signs on the roadmap to a strategy for assuring the safe application and use of nanomaterials.
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Keywords of People