Founder Effect
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Subject Areas on Research
- A founder mutation in the Ashkenazi Jewish population affecting messenger RNA splicing of the CCM2 gene causes cerebral cavernous malformations.
- An alternative to the search for single polymorphisms: toward molecular personality scales for the five-factor model.
- BRCA germline mutations in Jewish patients with pancreatic adenocarcinoma.
- Common mutation in the PHKA2 gene with variable phenotype in patients with liver phosphorylase b kinase deficiency.
- Different spectra of genomic deletions within the CCM genes between Italian and American CCM patient cohorts.
- Distribution and medical impact of loss-of-function variants in the Finnish founder population.
- Genetic analysis of a family with hereditary glomuvenous malformations.
- Genetic variation in the spread of Drosophila subobscura from a nonequilibrium population.
- High genetic diversity in a remote island population system: sans sex.
- Immunological and virological mechanisms of vaccine-mediated protection against SIV and HIV.
- Impact of immune escape mutations on HIV-1 fitness in the context of the cognate transmitted/founder genome.
- Molecular genetic basis and prevalence of glycogen storage disease type IIIA in the Faroe Islands.
- Molecular identification, cloning and characterization of transmitted/founder HIV-1 subtype A, D and A/D infectious molecular clones.
- Molecular testing for the BRCA1 and BRCA2 Ashkenazi Jewish founder mutations: a report on the College of American Pathologists proficiency testing surveys.
- Multilocus coalescent analyses reveal the demographic history and speciation patterns of mouse lemur sister species.
- One haploid parent contributes 100% of the gene pool for a widespread species in northwest North America.
- Origins and prevalence of the American Founder Mutation of MSH2.
- Parkin-proven disease: common founders but divergent phenotypes.
- Personality traits in Sardinia: testing founder population effects on trait means and variances.
- Strong founder effect in Drosophila pseudoobscura colonizing New Zealand from North America.
- Two common endoglin mutations in families with hereditary hemorrhagic telangiectasia in the Netherlands Antilles: evidence for a founder effect.
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Keywords of People
- Ferrari, Guido, Professor in Surgery, Molecular Genetics and Microbiology