Analgesics, Non-Narcotic

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  Subject Areas on Research

  • A randomized, double-blind, crossover clinical trial of diclofenac plus misoprostol versus acetaminophen in patients with osteoarthritis of the hip or knee. 
  • A selective inhibitor of cyclooxygenase-2 reverses endotoxin-induced pyretic responses in non-human primates. 
  • Adenosine as a non-opioid analgesic in the perioperative setting. 
  • Administration of Oral Acetaminophen to Reduce Costs for the Hysterectomy Patient at a Community Hospital. 
  • Alternating ibuprofen and acetaminophen in the treatment of febrile children: a pilot study [ISRCTN30487061]. 
  • Analgesia After Cesarean Delivery in the United States 2008-2018: A Retrospective Cohort Study. 
  • Artificial sweeteners and salts producing a metallic taste sensation activate TRPV1 receptors. 
  • Association Among Opioid Use, Treatment Preferences, and Perceptions of Physician Treatment Recommendations in Patients With Neck and Back Pain. 
  • Benzyl alcohol protects against acetaminophen hepatotoxicity by inhibiting cytochrome P450 enzymes but causes mitochondrial dysfunction and cell death at higher doses. 
  • Body temperature is a poor predictor of malaria parasitaemia in children with acute diarrhoea. 
  • Carbamazepine extended-release capsules: a new treatment option for bipolar I disorder. 
  • Changes in osmolality sensitize the response to capsaicin in trigeminal sensory neurons. 
  • Chronic pain and analgesic use in CKD: implications for patient safety. 
  • Chronic salicylism resulting in noncardiogenic pulmonary edema requiring hemodialysis. 
  • Contribution of CYP2E1 and CYP3A to acetaminophen reactive metabolite formation. 
  • Demographic and Clinical Factors Associated With Nonsurgical Osteoarthritis Treatment Among Patients in Outpatient Clinics. 
  • Dexmedetomidine related cardiac arrest in a patient with permanent pacemaker; a cautionary tale. 
  • Dual Role of Epidermal Growth Factor Receptor in Liver Injury and Regeneration after Acetaminophen Overdose in Mice. 
  • Effects of Acetaminophen on Oxidant and Irritant Respiratory Tract Responses to Environmental Tobacco Smoke in Female Mice. 
  • Epigenetic alterations in cytochrome P450 oxidoreductase (Por) in sperm of rats exposed to tetrahydrocannabinol (THC). 
  • Equal antipyretic effectiveness of oral and rectal acetaminophen: a randomized controlled trial [ISRCTN11886401]. 
  • Ethnomedicinally selected plants as sources of potential analgesic compounds: indication of in vitro biological activity in receptor binding assays. 
  • Evaluating the Implementation of a Preemptive, Multimodal Analgesia Protocol in a Plastic Surgery Office. 
  • Fourth Consensus Guidelines for the Management of Postoperative Nausea and Vomiting. 
  • Gastric motility function in critically ill patients tolerant vs intolerant to gastric nutrition. 
  • Glutathione and arginine levels: Predictors for acetaminophen-associated asthma exacerbation? 
  • Hepatic failure after rectal acetaminophen. 
  • Impact of a multimodal analgesic protocol modification on opioid consumption after cesarean delivery: a retrospective cohort study. 
  • Impact of intraoperative dexmedetomidine on postoperative analgesia following gynecologic surgery. 
  • Impact of liposomal bupivacaine administration on postoperative pain in patients undergoing total knee replacement. 
  • Induction of mitochondrial biogenesis protects against acetaminophen hepatotoxicity. 
  • Intraoperative ketorolac and eye pain after viteoretinal surgery: a prospective, randomized, placebo-controlled study. 
  • Intravenous Acetaminophen Does Not Decrease Persistent Surgical Pain After Cardiac Surgery. 
  • Intravenous acetaminophen analgesia after cardiac surgery: A randomized, blinded, controlled superiority trial. 
  • Intravenous acetaminophen: Can the benefit outweigh the cost in selected patients? 
  • Is Opioid-free Post-Vasectomy Analgesia a Pain? A Single Surgeon Experience. 
  • Letter to the Editor on "Randomized Prospective Trial Comparing the Use of Intravenous Versus Oral Acetaminophen in Total Joint Arthroplasty". 
  • Long-term follow-up of amitriptyline treatment for idiopathic cough. 
  • Lower susceptibility of female mice to acetaminophen hepatotoxicity: Role of mitochondrial glutathione, oxidant stress and c-jun N-terminal kinase. 
  • Multicenter study of acetaminophen hepatotoxicity reveals the importance of biological endpoints in genomic analyses. 
  • Multimodal Pain Management for Major Joint Replacement Surgery. 
  • No advantage of A beta 42-lowering NSAIDs for prevention of Alzheimer dementia in six pooled cohort studies. 
  • Nonopioid Treatments for Chronic Pain-Integrating Multimodal Biopsychosocial Approaches to Pain Management. 
  • Nonsteroidal anti-inflammatory drugs and acetaminophen in the treatment of an acute muscle injury. 
  • Opposite function of dopamine D1 and N-methyl-D-aspartate receptors in striatal cannabinoid-mediated signaling. 
  • Oral Multimodal Analgesia for Total Joint Arthroplasty. 
  • Pain Management in Patients With Hidradenitis Suppurativa Requiring Surgery. 
  • Patient Satisfaction and Pain Control Using an Opioid-Sparing Postoperative Pathway. 
  • Patient demographics and clinical characteristics influence opioid and nonopioid pain management prescriptions of primary care NPs, PAs, and physicians. 
  • Patient preference in a crossover clinical trial of patients with osteoarthritis of the knee or hip: face validity of self-report questionnaire ratings. 
  • Pharmacologic targeting of β-catenin improves fracture healing in old mice. 
  • Pharmacologically targeting beta-catenin for NF1 associated deficiencies in fracture repair. 
  • Progesterone is neuroprotective after acute experimental spinal cord trauma in rats. 
  • Randomized Population Pharmacokinetic Analysis and Safety of Intravenous Acetaminophen for Acute Postoperative Pain in Neonates and Infants. 
  • Randomized trial of the effect of antipyresis by metamizol, propacetamol or external cooling on metabolism, hemodynamics and inflammatory response. 
  • Reduction of pain and nausea after laparoscopic sterilization with bupivacaine, metoclopramide, scopolamine, ketorolac, and gastric suctioning. 
  • Skeletal muscle PGF(2)(alpha) and PGE(2) in response to eccentric resistance exercise: influence of ibuprofen acetaminophen. 
  • Suppression of prostaglandin E2 by malaria parasite products and antipyretics promotes overproduction of tumor necrosis factor-alpha: association with the pathogenesis of childhood malarial anemia. 
  • Supratherapeutic dosing of acetaminophen among hospitalized patients. 
  • The metabotropic glutamate receptor subtype 5 antagonist fenobam is analgesic and has improved in vivo selectivity compared with the prototypical antagonist 2-methyl-6-(phenylethynyl)-pyridine. 
  • The role of intravenous acetaminophen in multimodal pain protocols for perioperative orthopedic patients. 
  • The role of oxidative stress, inflammation and acetaminophen exposure from birth to early childhood in the induction of autism. 
  • The β-adrenoceptor agonist isoproterenol rescues acetaminophen-injured livers through increasing progenitor numbers by Wnt in mice. 
  • Therapeutic Implications of Peripheral Nerve Hyperexcitability in Muscle Cramping: A Retrospective Review. 
  • Treatment considerations for patients with neuropathic pain and other medical comorbidities. 
  • Underutilization of Acetaminophen in Older Adult Trauma Patients. 
  • Use of Dexmedetomidine in a Parturient With Multiple Endocrine Neoplasia Type 2A Undergoing Adrenalectomy and Thyroidectomy: A Case Report. 
  • Warfarin and acetaminophen interaction: a summary of the evidence and biologic plausibility.