Interleukin-13
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Subject Areas on Research
- Aberrant production of IL-13 by T cells promotes exocrinopathy in Id3 knockout mice.
- Airway fibroblasts in asthma manifest an invasive phenotype.
- Allergen-induced airway disease is mouse strain dependent.
- Bcl-3 acts as an innate immune modulator by controlling antimicrobial responses in keratinocytes.
- Blocking Interleukin (IL)4- and IL13-Mediated Phosphorylation of STAT6 (Tyr641) Decreases M2 Polarization of Macrophages and Protects Against Macrophage-Mediated Radioresistance of Inflammatory Breast Cancer.
- Both Hematopoietic- and Non-hematopoietic-derived {beta}-arrestin-2 Regulates Murine Allergic Airway Disease.
- Characterization of skin cytokines in bullous pemphigoid and pemphigus vulgaris.
- Clinical utility of a patient-specific algorithm for simulating intracerebral drug infusions.
- Contribution of IL-13 to early exocrinopathy in Id3-/- mice.
- Convection-enhanced delivery of cintredekin besudotox (interleukin-13-PE38QQR) followed by radiation therapy with and without temozolomide in newly diagnosed malignant gliomas: phase 1 study of final safety results.
- Cytokine expression by invariant natural killer T cells is tightly regulated throughout development and settings of type-2 inflammation.
- Cytokine induction of the ability of human monocyte CD44 to bind hyaluronan is mediated primarily by TNF-alpha and is inhibited by IL-4 and IL-13.
- Direct intracerebral delivery of cintredekin besudotox (IL13-PE38QQR) in recurrent malignant glioma: a report by the Cintredekin Besudotox Intraparenchymal Study Group.
- ERK1/2 mitogen-activated protein kinase selectively mediates IL-13-induced lung inflammation and remodeling in vivo.
- Effect of Aging on Adipose Tissue Inflammation in the Knee Joints of F344BN Rats.
- Effect of imaging and catheter characteristics on clinical outcome for patients in the PRECISE study.
- Effect of preexposure to ultrafine carbon black on respiratory syncytial virus infection in mice.
- Exposure to particulate hexavalent chromium exacerbates allergic asthma pathology.
- IL-13 and IL-1beta promote lung fibroblast growth through coordinated up-regulation of PDGF-AA and PDGF-Ralpha.
- IL-13 in asthma and allergic disease: asthma phenotypes and targeted therapies.
- IL-13 receptor α2-arginase 2 pathway mediates IL-13-induced pulmonary hypertension.
- IL-6 receptor α defines effector memory CD8+ T cells producing Th2 cytokines and expanding in asthma.
- Induction of hyperintense signal on T2-weighted MR images correlates with infusion distribution from intracerebral convection-enhanced delivery of a tumor-targeted cytotoxin.
- Inhibition of NF-kappaB activation reduces the tissue effects of transgenic IL-13.
- Interleukin-13 disrupts type 2 pneumocyte stem cell activity.
- Interleukin-13 induces collagen type-1 expression through matrix metalloproteinase-2 and transforming growth factor-β1 in airway fibroblasts in asthma.
- Interleukin-13 stimulates the proliferation of lung myofibroblasts via a signal transducer and activator of transcription-6-dependent mechanism: a possible mechanism for the development of airway fibrosis in asthma.
- Intracerebral infusate distribution by convection-enhanced delivery in humans with malignant gliomas: descriptive effects of target anatomy and catheter positioning.
- Meteorin-like is a hormone that regulates immune-adipose interactions to increase beige fat thermogenesis.
- Molecular characterization of inflammatory genes in sentinel and nonsentinel nodes in melanoma.
- Opposing actions of Stat1 and Stat6 on IL-13-induced up-regulation of early growth response-1 and platelet-derived growth factor ligands in pulmonary fibroblasts.
- Phase III randomized trial of CED of IL13-PE38QQR vs Gliadel wafers for recurrent glioblastoma.
- Poor drug distribution as a possible explanation for the results of the PRECISE trial.
- Role for hedgehog pathway in regulating growth and function of invariant NKT cells.
- Role of CCR5 in the pathogenesis of IL-13-induced inflammation and remodeling.
- Role of JAK3 in CD40-mediated signaling.
- Role of Matrix Metalloproteinases-1 and -2 in Interleukin-13-Suppressed Elastin in Airway Fibroblasts in Asthma.
- Role of early growth response-1 (Egr-1) in interleukin-13-induced inflammation and remodeling.
- Safety of intraparenchymal convection-enhanced delivery of cintredekin besudotox in early-phase studies.
- The IL-2 receptor gamma c chain does not function as a subunit shared by the IL-4 and IL-13 receptors. Implication for the structure of the IL-4 receptor.
- The benefits of restraint: a pivotal role for IL-13 in hepatic glucose homeostasis.
- The extracellular matrix protein mindin regulates trafficking of murine eosinophils into the airspace.
- The role of IL-13 in the generation of dendritic cells in vitro.
- β-Arrestin-2 mediates the proinflammatory effects of proteinase-activated receptor-2 in the airway.
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Keywords of People
- Buckley, Rebecca Hatcher, James Buren Sidbury Distinguished Professor of Pediatrics, in the School of Medicine, Immunology
- Choi, Steven Sok, Associate Professor of Medicine, Medicine, Gastroenterology
- Sampson, John Howard, Robert H., M.D. and Gloria Wilkins Professor of Neurosurgery, in the School of Medicine, Biomedical Engineering
- Sunday, Mary Elizabeth Anne, Professor of Pathology, Cell Biology