APACHE
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Subject Areas on Research
- A brief report: the use of high-frequency oscillatory ventilation for severe pulmonary contusion.
- A comparison of three techniques for rapid model development: an application in patient risk-stratification.
- A descriptive evaluation of transfusion practices in patients receiving mechanical ventilation.
- A study of proactive ethics consultation for critically and terminally ill patients with extended lengths of stay.
- A trial of thyroxine in acute renal failure.
- APOE polymorphism is associated with risk of severe sepsis in surgical patients.
- Acute pancreatitis and fulminant hepatic failure.
- Acute renal failure in recipients of organ transplantation and nontransplantation patients: comparison of characteristics and mortality.
- Admission cell free DNA levels predict 28-day mortality in patients with severe sepsis in intensive care.
- Aggressive versus conservative initiation of antimicrobial treatment in critically ill surgical patients with suspected intensive-care-unit-acquired infection: a quasi-experimental, before and after observational cohort study.
- An evaluation of factors influencing Bayesian learning systems.
- Association of gender with outcomes in critically ill patients.
- Circulating tetrahydrobiopterin concentrations in patients with septic shock.
- Colistin-resistant isolates of Klebsiella pneumoniae emerging in intensive care unit patients: first report of a multiclonal cluster.
- Comparison of caspofungin and amphotericin B for invasive candidiasis.
- Cost-effectiveness of recombinant human activated protein C and the influence of severity of illness in the treatment of patients with severe sepsis.
- Costs and outcomes among hemodialysis-dependent patients with methicillin-resistant or methicillin-susceptible Staphylococcus aureus bacteremia.
- D-dimer assay predicts mortality in critically ill patients without disseminated intravascular coagulation or venous thromboembolic disease.
- Decompressive laparotomy for refractory intracranial hypertension after traumatic brain injury.
- Development and preliminary evaluation of a telephone-based mindfulness training intervention for survivors of critical illness.
- Early acute lung injury: criteria for identifying lung injury prior to the need for positive pressure ventilation*.
- Early predictors of in-hospital death in infective endocarditis.
- Effect of neuromuscular blockers and opiates on the cerebrovascular response to endotracheal suctioning in adults with severe head injuries.
- Elevated troponin I levels in acute liver failure: is myocardial injury an integral part of acute liver failure?
- Evaluation of risk indices in continuous-flow left ventricular assist device patients.
- Gastric motility function in critically ill patients tolerant vs intolerant to gastric nutrition.
- Identification of comatose patients at high risk for death or severe disability. SUPPORT Investigators. Understand Prognoses and Preferences for Outcomes and Risks of Treatments.
- Improvements in pulmonary and general critical care reduces mortality following ventilator-associated pneumonia.
- Late mortality in patients with severe acute pancreatitis.
- Mortality prediction at admission to intensive care: a comparison of microalbuminuria with acute physiology scores after 24 hours.
- Necrotizing pancreatitis: diagnosis and management.
- Neutrophils with myeloid derived suppressor function deplete arginine and constrain T cell function in septic shock patients.
- Optimizing the dose of glutamine dipeptides and antioxidants in critically ill patients: a phase I dose-finding study.
- Outcome of lung transplant patients admitted to the medical ICU.
- Outcomes following acute exacerbation of severe chronic obstructive lung disease. The SUPPORT investigators (Study to Understand Prognoses and Preferences for Outcomes and Risks of Treatments)
- Patients with DNR orders in the operating room: surgery, resuscitation, and outcomes. SUPPORT Investigators. Study to Understand Prognoses and Preferences for Outcomes and Risks of Treatments.
- Patterns of use of perioperative angiotensin-converting enzyme inhibitors in coronary artery bypass graft surgery with cardiopulmonary bypass: effects on in-hospital morbidity and mortality.
- Predictors of the severity of acute pancreatitis in patients with HIV infection or AIDS.
- Preventive use of noninvasive ventilation after extubation: a prospective, multicenter randomized controlled trial.
- Prognostic accuracy of Acute Physiology and Chronic Health Evaluation II scores in critically ill cancer patients.
- Prognostic and diagnostic value of plasma soluble suppression of tumorigenicity-2 concentrations in acute respiratory distress syndrome.
- Prognostic value of plasma N-terminal probrain natriuretic peptide levels in the acute respiratory distress syndrome.
- Relationship of body mass index to subsequent mortality among seriously ill hospitalized patients. SUPPORT Investigators. The Study to Understand Prognoses and Preferences for Outcome and Risks of Treatments.
- Risk factors for mortality in patients admitted to intensive care units with pneumonia.
- Risk factors for nosocomial pneumonia: comparing adult critical-care populations.
- Safety and potential efficacy of an aerosolized surfactant in human sepsis-induced adult respiratory distress syndrome.
- Standard subcutaneous dosing of unfractionated heparin for venous thromboembolism prophylaxis in surgical ICU patients leads to subtherapeutic factor Xa inhibition.
- The SUPPORT prognostic model. Objective estimates of survival for seriously ill hospitalized adults. Study to understand prognoses and preferences for outcomes and risks of treatments.
- The effectiveness of right heart catheterization in the initial care of critically ill patients. SUPPORT Investigators.
- The surgical intensive care unit optimal mobility score predicts mortality and length of stay.
- The utility of acute physiology and chronic health evaluation II scores for prediction of mortality among intensive care unit (ICU) and non-ICU patients with methicillin-resistant Staphylococcus aureus bacteremia.
- Towards precision medicine: Accurate predictive modeling of infectious complications in combat casualties.
- Transfusion of fresh frozen plasma in critically ill surgical patients is associated with an increased risk of infection.
- Withholding versus withdrawing life-sustaining treatment: patient factors and documentation associated with dialysis decisions.
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Keywords of People
- Laskowitz, Daniel Todd, Professor of Neurology, Duke Innovation & Entrepreneurship