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Subject Areas on Research
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17Beta-estradiol suppresses TLR3-induced cytokine and chemokine production in endometrial epithelial cells.
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A catalytic antioxidant (AEOL 10150) attenuates expression of inflammatory genes in stroke.
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A cell-intrinsic role for Mst1 in regulating thymocyte egress.
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A genomic- and proteomic-based hypothesis on the eclectic effects of systemic interleukin-2 administration in the context of melanoma-specific immunization.
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A model for migratory B cell oscillations from receptor down-regulation induced by external chemokine fields.
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Abl family kinases modulate T cell-mediated inflammation and chemokine-induced migration through the adaptor HEF1 and the GTPase Rap1.
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Aerobic exercise attenuates airway inflammatory responses in a mouse model of atopic asthma.
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Airway inflammation and responsiveness in prostaglandin H synthase-deficient mice exposed to bacterial lipopolysaccharide.
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Alopecia in IL-10-deficient mouse pups is c-kit-dependent and can be triggered by iron deficiency.
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Alpha-chemokine receptor blockade reduces high mobility group box 1 protein-induced lung inflammation and injury and improves survival in sepsis.
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An Engineered Tumor-on-a-Chip Device with Breast Cancer-Immune Cell Interactions for Assessing T-cell Recruitment.
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Analysis of the immune responses in chimpanzees infected with HIV type 1 isolates.
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Anti-VEGF treatment-resistant pancreatic cancers secrete proinflammatory factors that contribute to malignant progression by inducing an EMT cell phenotype.
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Anti-neutrophil chemokine preserves alveolar development in hyperoxia-exposed newborn rats.
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Anti-phospholipid human monoclonal antibodies inhibit CCR5-tropic HIV-1 and induce beta-chemokines.
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Articular ankle fracture results in increased synovitis, synovial macrophage infiltration, and synovial fluid concentrations of inflammatory cytokines and chemokines.
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Assessing activation states in microglia.
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Assessment of the utility of biomarkers of osteoarthritis in the guinea pig.
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Associations between maternal cytokine levels during gestation and measures of child cognitive abilities and executive functioning.
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Autophagy enhances NFκB activity in specific tissue macrophages by sequestering A20 to boost antifungal immunity.
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Bedside Allogeneic Erythrocyte Washing with a Cell Saver to Remove Cytokines, Chemokines, and Cell-derived Microvesicles.
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Biased agonism as a mechanism for differential signaling by chemokine receptors.
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Biased agonism at chemokine receptors.
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Biased agonists of the chemokine receptor CXCR3 differentially control chemotaxis and inflammation.
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Biologic predictors of clinical improvement in rituximab-treated refractory myositis.
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Blood-derived inflammatory dendritic cells in lymph nodes stimulate acute T helper type 1 immune responses.
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Bye-bye TRALI: by understanding and innovation.
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CD4(+) T cells contribute to the remodeling of the microenvironment required for sustained tumor regression upon oncogene inactivation.
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CD8 positive T cells influence antigen-specific immune responses through the expression of chemokines.
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CXCL10/IP-10 is a biomarker and mediator for Kawasaki disease.
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CXCR3 and CCR5 ligands in rheumatoid arthritis synovium.
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CaMKK2 in myeloid cells is a key regulator of the immune-suppressive microenvironment in breast cancer.
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Calcium/calmodulin-dependent protein kinase kinase 2 regulates macrophage-mediated inflammatory responses.
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Cas13d knockdown of lung protease Ctsl prevents and treats SARS-CoV-2 infection.
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Cell type- and species-specific host responses to Toxoplasma gondii and its near relatives.
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Cellular and molecular mechanisms of pomegranate juice-induced anti-metastatic effect on prostate cancer cells.
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Changes in novel biomarkers of disease activity in juvenile and adult dermatomyositis are sensitive biomarkers of disease course.
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Chemerin suppresses hepatocellular carcinoma metastasis through CMKLR1-PTEN-Akt axis.
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Chemerin-activated functions of CMKLR1 are regulated by G protein-coupled receptor kinase 6 (GRK6) and β-arrestin 2 in inflammatory macrophages.
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Chemokine Signaling in Allergic Contact Dermatitis: Toward Targeted Therapies.
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Chemokine ligand and receptor expression in the pregnant uterus: reciprocal patterns in complementary cell subsets suggest functional roles.
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Chemokine mediated control of dendritic cell migration and function.
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Chemokine production by G protein-coupled receptor activation in a human mast cell line: roles of extracellular signal-regulated kinase and NFAT.
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Chemokine-adjuvanted electroporated DNA vaccine induces substantial protection from simian immunodeficiency virus vaginal challenge.
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Chemokines and B-cell homing to follicles.
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Chemokines and the hippocampus: a new perspective on hippocampal plasticity and vulnerability.
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Chemokines as adjuvants for immunotherapy: implications for immune activation with CCL3.
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Chemokines have diverse abilities to form solid phase gradients.
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Circulating Biomarkers of Inflammation and Ovarian Cancer Risk in the Nurses' Health Studies.
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Connexin-43 induces chemokine release from spinal cord astrocytes to maintain late-phase neuropathic pain in mice.
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Contributions of E1A to mouse adenovirus type 1 pathogenesis following intranasal inoculation.
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Control of thymic T cell maturation, deletion and egress by the RNA-binding protein HuR.
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Correlates of nontransmission in US women at high risk of human immunodeficiency virus type 1 infection through sexual exposure.
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Cromolyn ameliorates acute and chronic injury in a rat lung transplant model.
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Cross-sectional detection of acute HIV infection: timing of transmission, inflammation and antiretroviral therapy.
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Cryptococcus neoformans Chitin Synthase 3 Plays a Critical Role in Dampening Host Inflammatory Responses.
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Cytokine profiling using monocytes/macrophages cultured on common biomaterials with a range of surface chemistries.
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Dendritic cell responses to early murine cytomegalovirus infection: subset functional specialization and differential regulation by interferon alpha/beta.
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Dendritic cell transmigration through brain microvessel endothelium is regulated by MIP-1alpha chemokine and matrix metalloproteinases.
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Development of a membrane-anchored chemerin receptor agonist as a novel modulator of allergic airway inflammation and neuropathic pain.
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Differential pulmonary transcriptomic profiles in murine lungs infected with low and highly virulent influenza H3N2 viruses reveal dysregulation of TREM1 signaling, cytokines, and chemokines.
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Differential role for TLR3 in respiratory syncytial virus-induced chemokine expression.
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ERK1/2 mitogen-activated protein kinase selectively mediates IL-13-induced lung inflammation and remodeling in vivo.
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Effect of preexposure to ultrafine carbon black on respiratory syncytial virus infection in mice.
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Effects of oxidized LDL on mononuclear phagocytes: inhibition of induction of four inflammatory cytokine gene RNAs, release of NO, and cytolysis of tumor cells.
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Elevated chemokine responses are maintained in lungs after clearance of viral infection.
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Elevation of CXCR3-binding chemokines in urine indicates acute renal-allograft dysfunction.
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Emerging targets in neuroinflammation-driven chronic pain.
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Enhanced expression of cytokines and chemokines by blood monocytes to in vitro lipopolysaccharide stimulation are associated with hostility and severity of depressive symptoms in healthy women.
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Environmental enrichment alters glial antigen expression and neuroimmune function in the adult rat hippocampus.
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Essential role of Smad3 in infarct healing and in the pathogenesis of cardiac remodeling.
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FACS analysis of neuronal-glial interactions in the nucleus accumbens following morphine administration.
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Gene Expression Profile of Dendritic Cell-Tumor Cell Hybrids Determined by Microarrays and Its Implications for Cancer Immunotherapy.
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Genetic and cellular evidence of decreased inflammation associated with reduced incidence of posttraumatic arthritis in MRL/MpJ mice.
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Glomerular type 1 angiotensin receptors augment kidney injury and inflammation in murine autoimmune nephritis.
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HSV oncolytic therapy upregulates interferon-inducible chemokines and recruits immune effector cells in ovarian cancer.
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High-resolution, noninvasive longitudinal live imaging of immune responses.
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Highly conserved gene expression profiles in humans with allergic rhinitis altered by immunotherapy.
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Host-Pathogen Interactions and Chronic Lung Allograft Dysfunction.
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Human Placental Syncytiotrophoblasts Restrict Toxoplasma gondii Attachment and Replication and Respond to Infection by Producing Immunomodulatory Chemokines.
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IFN-beta1a inhibits the secretion of Th17-polarizing cytokines in human dendritic cells via TLR7 up-regulation.
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Immunological biomarkers in dermatomyositis.
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Immunology of infection caused by Cryptococcus neoformans.
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Immunotherapy for HIV.
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Impact of early life exposure to ionizing radiation on influenza vaccine response in an elderly Japanese cohort.
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In vitro resistance to thrombin-induced platelet microbicidal protein among clinical bacteremic isolates of Staphylococcus aureus correlates with an endovascular infectious source.
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In vitro resistance to thrombin-induced platelet microbicidal protein in isolates of Staphylococcus aureus from endocarditis patients correlates with an intravascular device source.
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In vivo cytokine-associated responses to biomaterials.
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Innate-like Gene Expression of Lung-Resident Memory CD8+ T Cells during Experimental Human Influenza: A Clinical Study.
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Interferon-regulated chemokine score associated with improvement in disease activity in refractory myositis patients treated with rituximab.
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Interleukin-6 and type I interferon-regulated genes and chemokines mark disease activity in dermatomyositis.
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Intracellular CMTM2 negatively regulates human immunodeficiency virus type-1 transcription through targeting the transcription factors AP-1 and CREB.
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Large-Scale Characterization of Systemic Sclerosis Serum Protein Profile: Comparison to Peripheral Blood Cell Transcriptome and Correlations With Skin/Lung Fibrosis.
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Localized increase of chemokines in the lumen of human cerebral aneurysms.
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Location bias contributes to functionally selective responses of biased CXCR3 agonists.
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Loss of Ranbp2 in motoneurons causes disruption of nucleocytoplasmic and chemokine signaling, proteostasis of hnRNPH3 and Mmp28, and development of amyotrophic lateral sclerosis-like syndromes.
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Low-dose mucosal simian immunodeficiency virus infection restricts early replication kinetics and transmitted virus variants in rhesus monkeys.
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Lysophospholipids Contribute to Oxaliplatin-Induced Acute Peripheral Pain.
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Microglial-neuronal interactions during neurodegenerative diseases.
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Modulation of cytokines and chemokines, limited pulmonary vascular bed permeability, and prevention of septicemia and death with ceftriaxone and interleukin-10 in pneumococcal pneumonia.
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Molecular characterization of inflammatory genes in sentinel and nonsentinel nodes in melanoma.
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Molecular correlates in urine for the obesity and prostatic inflammation of BPH/LUTS patients.
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Molecular editing of cellular responses by the high-affinity receptor for IgE.
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Monocyte polarization in children with falciparum malaria: relationship to nitric oxide insufficiency and disease severity.
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Mouse strain differences in the chemokine response to acute lung infection with a murine gammaherpesvirus.
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NAD(P)H quinone oxidoreductase 1 is essential for ozone-induced oxidative stress in mice and humans.
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Neutrophils Create an ImpeNETrable Shield between Tumor and Cytotoxic Immune Cells.
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Nitric oxide is necessary for CC-class chemokine expression in endotoxin-stimulated ANA-1 murine macrophages.
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Noncytolytic CD8 T cell-mediated suppression of HIV replication.
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Noninvasive detection of acute and chronic injuries in human renal transplant by elevation of multiple cytokines/chemokines in urine.
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Novel nuclear target for thrombin: activation of the Elk1 transcription factor leads to chemokine gene expression.
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Oncolytic virus-derived type I interferon restricts CAR T cell therapy.
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Opposing actions of renal tubular- and myeloid-derived porcupine in obstruction-induced kidney fibrosis.
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PDGF-AA mediates mesenchymal stromal cell chemotaxis to the head and neck squamous cell carcinoma tumor microenvironment.
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Pathogenesis of pneumococcal pneumonia in cyclophosphamide-induced leukopenia in mice.
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Pathogenic effector functions of ACPA: Where do we stand?
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Peripheral blood cytokine and chemokine profiles in juvenile localized scleroderma: T-helper cell-associated cytokine profiles.
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Persistent bacteremia due to methicillin-resistant Staphylococcus aureus infection is associated with agr dysfunction and low-level in vitro resistance to thrombin-induced platelet microbicidal protein.
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Poxvirus genomes encode a secreted, soluble protein that preferentially inhibits beta chemokine activity yet lacks sequence homology to known chemokine receptors.
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Prevalence of chemokine and chemokine receptor polymorphisms in seroprevalent children with symptomatic HIV-1 infection in the United States.
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Profiling heparin-chemokine interactions using synthetic tools.
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Proteomic dissection of LPS-inducible, PHF8-dependent secretome reveals novel roles of PHF8 in TLR4-induced acute inflammation and T cell proliferation.
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Redirecting migration of T cells to chemokine secreted from tumors by genetic modification with CXCR2.
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Regulation of I-309 gene expression in human monocytes by endogenous interleukin-1.
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Regulation of corneal inflammation by neutrophil-dependent cleavage of keratan sulfate proteoglycans as a model for breakdown of the chemokine gradient.
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Regulation of human chemokine receptors CXCR4. Role of phosphorylation in desensitization and internalization.
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Response of adipose tissue to early infection with Trypanosoma cruzi (Brazil strain).
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Responses of serum chemokines to dramatic changes of air pollution levels, a panel study.
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Results from a human renal allograft tolerance trial evaluating T-cell depletion with alemtuzumab combined with deoxyspergualin.
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Role of Immune Response, Inflammation, and Tumor Immune Response-Related Cytokines/Chemokines in Melanoma Progression.
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Role of T cell recruitment and chemokine-regulated intra-graft T cell motility patterns in corneal allograft rejection.
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Salmonella disrupts lymph node architecture by TLR4-mediated suppression of homeostatic chemokines.
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Selective modification of antigen-specific T cells by RNA electroporation.
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Serum levels of TARC, MDC, IL-10, and soluble CD163 in Hodgkin lymphoma: a SWOG S0816 correlative study.
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Serum proteins reflecting inflammation, injury and repair as biomarkers of disease activity in ANCA-associated vasculitis.
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Shear flow-dependent integration of apical and subendothelial chemokines in T-cell transmigration: implications for locomotion and the multistep paradigm.
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Study of gastric fluid induced cytokine and chemokine expression in airway smooth muscle cells and airway remodeling.
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TNFR2 interposes the proliferative and NF-κB-mediated inflammatory response by podocytes to TNF-α.
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The 12-CK Score: Global Measurement of Tertiary Lymphoid Structures.
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The effects of HHV-8 vMIP-II on SIVmac251 infection and replication competent and incompetent SIVmac239Delta3 vectors.
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The immunologic constant of rejection.
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The inflammatory milieu in idiopathic inflammatory myositis.
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The matrix protein Fibulin-5 is at the interface of tissue stiffness and inflammation in fibrosis.
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The relation of severity of depressive symptoms to monocyte-associated proinflammatory cytokines and chemokines in apparently healthy men.
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The role of chemokines and chemokine receptors in pulmonary arterial hypertension.
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The role of chemokines in hypertension and consequent target organ damage.
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The role(s) of cytokines/chemokines in urinary bladder inflammation and dysfunction.
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The transcriptomic response of rat hepatic stellate cells to endotoxin: implications for hepatic inflammation and immune regulation.
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Therapeutic opportunities to prevent post-traumatic arthritis: Lessons from the natural history of arthritis after articular fracture.
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Two genes on A/J chromosome 18 are associated with susceptibility to Staphylococcus aureus infection by combined microarray and QTL analyses.
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Ubc9 overexpression and SUMO1 deficiency blunt inflammation after intestinal ischemia/reperfusion.
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Ultrafine carbon black particles enhance respiratory syncytial virus-induced airway reactivity, pulmonary inflammation, and chemokine expression.
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Vein graft neointimal hyperplasia is exacerbated by tumor necrosis factor receptor-1 signaling in graft-intrinsic cells.
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Visualization and characterization of inflammatory cell recruitment and migration through the corneal stroma in endotoxin-induced keratitis.
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mTORC1 in Thymic Epithelial Cells Is Critical for Thymopoiesis, T-Cell Generation, and Temporal Control of γδT17 Development and TCRγ/δ Recombination.
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p38 MAPK, microglial signaling, and neuropathic pain.
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Keywords of People
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Bilbo, Staci D.,
Haley Family Professor of Psycology and Neuroscience,
Psychology & Neuroscience
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Chen, Jun,
Professor of Medicine,
Duke Cancer Institute
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Gunn, Michael Dee,
Professor of Medicine,
Immunology
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Krangel, Michael S.,
George Barth Geller Distinguished Professor of Immunology,
Immunology
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MacLeod, Amanda S,
Adjunct Associate Professor in the Department of Dermatology,
Immunology
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Olson, Steven Arthur,
Goldner Jones Distinguished Professor of Orthopaedic Surgery,
Orthopaedic Surgery
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Sampson, John Howard,
Robert H., M.D. and Gloria Wilkins Professor of Neurosurgery, in the School of Medicine,
Biomedical Engineering
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Weinhold, Kent James,
Joseph W. and Dorothy W. Beard Distinguished Professor of Experimental Surgery,
Immunology