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Subject Areas on Research
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A Prognostic Model of Persistent Bacteremia and Mortality in Complicated Staphylococcus aureus Bloodstream Infection.
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A macrophage subpopulation recruited by CC chemokine ligand-2 clears apoptotic cells in noninfectious lung injury.
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A role for angiotensin II type 1 receptors on bone marrow-derived cells in the pathogenesis of angiotensin II-dependent hypertension.
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Adrenergic regulation of monocyte chemotactic protein 1 leads to enhanced macrophage recruitment and ovarian carcinoma growth.
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Angiopoietin-1 promotes atherosclerosis by increasing the proportion of circulating Gr1+ monocytes.
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Associations between the chemokine biomarker CCL2 and knee osteoarthritis outcomes: the Johnston County Osteoarthritis Project.
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Blood-derived inflammatory dendritic cells in lymph nodes stimulate acute T helper type 1 immune responses.
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C-C Motif Chemokine 5 Attenuates Angiotensin II-Dependent Kidney Injury by Limiting Renal Macrophage Infiltration.
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CX3CR1-dependent renal macrophage survival promotes Candida control and host survival.
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Cardiac gene expression profiling provides evidence for cytokinopathy as a molecular mechanism in Chagas' disease cardiomyopathy.
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Chemokines, neuronal-glial interactions, and central processing of neuropathic pain.
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Combined expression of A1 and A20 achieves optimal protection of renal proximal tubular epithelial cells.
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Comparison of free fructose and glucose to sucrose in the ability to cause fatty liver.
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Cytokines in proliferative diabetic retinopathy and proliferative vitreoretinopathy.
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Discriminating between latent and active tuberculosis with multiple biomarker responses.
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Dual action of TGF-beta1 on nasal-polyp derived fibroblasts.
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Early biomarkers of stroke.
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Effect of mutant IkappaB on cytokine-induced activation of NF-kappaB in cultured human RPE cells.
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Effects of lactogen resistance and GH deficiency on mouse metabolism: pancreatic hormones, adipocytokines, and expression of adiponectin and insulin receptors.
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Effects of oxidized LDL on mononuclear phagocytes: inhibition of induction of four inflammatory cytokine gene RNAs, release of NO, and cytolysis of tumor cells.
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Elevations of inflammatory proteins in neonatal blood are associated with obesity and overweight among 2-year-old children born extremely premature.
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Enhanced expression of cytokines and chemokines by blood monocytes to in vitro lipopolysaccharide stimulation are associated with hostility and severity of depressive symptoms in healthy women.
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Essential role for Smad3 in regulating MCP-1 expression and vascular inflammation.
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Evaluation of host immune responses to pulmonary cryptococcosis using a temperature-sensitive C. neoformans calcineurin A mutant strain.
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Excess risk of temporomandibular disorder associated with cigarette smoking in young adults.
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Exosomal CCL2 from Tubular Epithelial Cells Is Critical for Albumin-Induced Tubulointerstitial Inflammation.
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Exploitation of Synthetic mRNA To Drive Immune Effector Cell Recruitment and Functional Reprogramming In Vivo.
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Heme: a novel inducer of MCP-1 through HO-dependent and HO-independent mechanisms.
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Host and environmental factors affect pulmonary responses measured in bronchoalveolar lavage.
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Human immunodeficiency virus (HIV) infects human arterial smooth muscle cells in vivo and in vitro: implications for the pathogenesis of HIV-mediated vascular disease.
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Human immunodeficiency virus (HIV)-1 infects human hepatic stellate cells and promotes collagen I and monocyte chemoattractant protein-1 expression: implications for the pathogenesis of HIV/hepatitis C virus-induced liver fibrosis.
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IL-17A Contributes to Lung Fibrosis in a Model of Chronic Pulmonary Graft-versus-host Disease.
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IRGM3 contributes to immunopathology and is required for differentiation of antigen-specific effector CD8+ T cells in experimental cerebral malaria.
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Impact of carbohydrate restriction in the context of obesity on prostate tumor growth in the Hi-Myc transgenic mouse model.
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Inflammation in coronary artery disease.
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Inflammation, platelets, and glycoprotein IIb/IIIa inhibitors.
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Interleukin-6 and type I interferon-regulated genes and chemokines mark disease activity in dermatomyositis.
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Isolation and structures of novel fungal metabolites as chemokine receptor (CCR2) antagonists.
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JNK-induced MCP-1 production in spinal cord astrocytes contributes to central sensitization and neuropathic pain.
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Low-level endotoxin induces potent inflammatory activation of human blood vessels: inhibition by statins.
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Lumbar Myeloid Cell Trafficking into Locomotor Networks after Thoracic Spinal Cord Injury.
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Lung-specific overexpression of CC chemokine ligand (CCL) 2 enhances the host defense to Streptococcus pneumoniae infection in mice: role of the CCL2-CCR2 axis.
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MCP1 SNPs and pulmonary tuberculosis in cohorts from West Africa, the USA and Argentina: lack of association or epistasis with IL12B polymorphisms.
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Mice that overexpress CC chemokine ligand 2 in their lungs show increased protective immunity to infection with Mycobacterium bovis bacille Calmette-Guérin.
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Moderate-intensity aerobic training program improves insulin sensitivity and inflammatory markers in a pilot study of morbidly obese minority teens.
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Molecular and cellular profiling of acute responses to total body radiation exposure in ovariectomized female cynomolgus macaques.
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Monocyte chemoattractant protein-1 is sufficient for the chemotaxis of monocytes and lymphocytes in transgenic mice but requires an additional stimulus for inflammatory activation.
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Nitric oxide is necessary for CC-class chemokine expression in endotoxin-stimulated ANA-1 murine macrophages.
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Organizing pneumonia in mice and men.
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Osteoblasts produce monocyte chemoattractant protein-1 in a murine model of Staphylococcus aureus osteomyelitis and infected human bone tissue.
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PECAM-1 dampens cytokine levels during LPS-induced endotoxemia by regulating leukocyte trafficking.
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Pathogenesis of pneumococcal pneumonia in cyclophosphamide-induced leukopenia in mice.
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Peripheral blood cytokine and chemokine profiles in juvenile localized scleroderma: T-helper cell-associated cytokine profiles.
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RANK, RANKL, OPG, and M-CSF expression in stromal cells during corneal wound healing.
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RNA-Seq and ChIP-Seq reveal SQSTM1/p62 as a key mediator of JunB suppression of NF-κB-dependent inflammation.
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Regulation of I-309 gene expression in human monocytes by endogenous interleukin-1.
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Regulation of endotoxin-induced proinflammatory activation in human coronary artery cells: expression of functional membrane-bound CD14 by human coronary artery smooth muscle cells.
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Relationship between markers of platelet activation and inflammation with disease activity in Wegener's granulomatosis.
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Role of C-C motif ligand 2 and C-C motif receptor 2 in murine pulmonary graft-versus-host disease after lipopolysaccharide inhalations.
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Safety, pharmacokinetics, and pharmacodynamic properties of oral DEBIO1143 (AT-406) in patients with advanced cancer: results of a first-in-man study.
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Serial measurement of monocyte chemoattractant protein-1 after acute coronary syndromes: results from the A to Z trial.
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Serum cytokine profiles in relapsing polychondritis suggest monocyte/macrophage activation.
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Serum levels of fibroblast growth factor 23 are elevated in patients with active Lupus nephritis.
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Soluble ICAM-1, MCP-1, and MIP-2 protein secretion by rat pleural mesothelial cells following exposure to amosite asbestos.
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Spinal CCL2 Promotes Central Sensitization, Long-Term Potentiation, and Inflammatory Pain via CCR2: Further Insights into Molecular, Synaptic, and Cellular Mechanisms.
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Spinal injection of TNF-α-activated astrocytes produces persistent pain symptom mechanical allodynia by releasing monocyte chemoattractant protein-1.
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Suppression of NF-kappaB-dependent proinflammatory gene expression in human RPE cells by a proteasome inhibitor.
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Suppression of tumor formation in vivo by expression of the JE gene in malignant cells.
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TRAF6 upregulation in spinal astrocytes maintains neuropathic pain by integrating TNF-α and IL-1β signaling.
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The chemokines IL-8, monocyte chemoattractant protein-1, and I-309 are monomers at physiologically relevant concentrations.
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The effect of inflammatory cell-derived MCP-1 loss on neuronal survival during chronic neuroinflammation.
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The relation of severity of depressive symptoms to monocyte-associated proinflammatory cytokines and chemokines in apparently healthy men.
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Upregulation of IL-1β, IL-6, and CCL-2 by a novel mouse model of pancreatic ischemia-reperfusion injury.
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Urinary Exosomes and Exosomal CCL2 mRNA as Biomarkers of Active Histologic Injury in IgA Nephropathy.
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Urine osteoprotegerin and monocyte chemoattractant protein-1 in lupus nephritis.
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Vein graft neointimal hyperplasia is exacerbated by tumor necrosis factor receptor-1 signaling in graft-intrinsic cells.
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Ventilation defects observed with hyperpolarized 3He magnetic resonance imaging in a mouse model of acute lung injury.
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[LMP-420, a new therapeutic approach for cerebral malaria?].
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β2- and β3-adrenergic receptors drive COMT-dependent pain by increasing production of nitric oxide and cytokines.
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Keywords of People
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Ferrari, Guido,
Professor in Surgery,
Molecular Genetics and Microbiology
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Gunn, Michael Dee,
Professor of Medicine,
Immunology
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Krangel, Michael S.,
George Barth Geller Distinguished Professor of Immunology,
Immunology
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Muir, Kelly Walton,
Associate Professor of Ophthalmology,
Ophthalmology, Glaucoma