Antigens, CD44
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Subject Areas on Research
- A blood group-related polymorphism of CD44 abolishes a hyaluronan-binding consensus sequence without preventing hyaluronan binding.
- A new twist to the leukocyte adhesion cascade: intimate cooperation is key.
- A novel role for HEB downstream or parallel to the pre-TCR signaling pathway during alpha beta thymopoiesis.
- ALDH activity selectively defines an enhanced tumor-initiating cell population relative to CD133 expression in human pancreatic adenocarcinoma.
- Activated T lymphocytes regulate hyaluronan binding to monocyte CD44 via production of IL-2 and IFN-gamma.
- All-trans retinoic acids induce differentiation and sensitize a radioresistant breast cancer cells to chemotherapy.
- An essential role for Prox1 in the induction of the lymphatic endothelial cell phenotype.
- Aqueous humor sCD44 concentration and visual field loss in primary open-angle glaucoma.
- Attenuated host resistance against Mycobacterium bovis BCG infection in mice lacking osteopontin.
- Brain inositol is a novel stimulator for promoting Cryptococcus penetration of the blood-brain barrier.
- CD44 expression is a feature of prostatic small cell carcinoma and distinguishes it from its mimickers.
- CD44+/CD24- breast cancer cells isolated from MCF-7 cultures exhibit enhanced angiogenic properties.
- CD44-SLC1A2 gene fusions in gastric cancer.
- CHML promotes liver cancer metastasis by facilitating Rab14 recycle.
- Cellular CD44S as a determinant of human immunodeficiency virus type 1 infection and cellular tropism.
- Cellular and molecular mechanisms of pomegranate juice-induced anti-metastatic effect on prostate cancer cells.
- Characterization of circulating T cells specific for tumor-associated antigens in melanoma patients.
- Coordinator's report--section 2D3.
- Cytokine induction of the ability of human monocyte CD44 to bind hyaluronan is mediated primarily by TNF-alpha and is inhibited by IL-4 and IL-13.
- Deletion of Trpm7 disrupts embryonic development and thymopoiesis without altering Mg2+ homeostasis.
- Distribution of CD44 variant isoforms in human skin: differential expression in components of benign and malignant epithelia.
- Donor Allospecific CD44high Central Memory T Cells Have Decreased Ability to Mediate Graft-vs.-Host Disease.
- Endogenous presenilin 1 redistributes to the surface of lamellipodia upon adhesion of Jurkat cells to a collagen matrix.
- Erythrocyte adhesion receptors: blood group antigens and related molecules.
- Erythrocyte blood group antigens: not so simple after all.
- Ex vivo glycan engineering of CD44 programs human multipotent mesenchymal stromal cell trafficking to bone.
- Expression of CD44 and variant isoforms in cultured human retinal pigment epithelial cells.
- Expression of CD44 molecules and CD44 ligands during human thymic fetal development: expression of CD44 isoforms is developmentally regulated.
- Expression of CD44 variants in human inflammatory synovitis.
- Expression of cell adhesion molecule CD44 in primary tumors of the liver: an immunohistochemical study.
- Expression of the cell adhesion molecule CD44 in gastric adenocarcinomas.
- Ezrin Orchestrates Signal Transduction in Airway Cells.
- Genetic deletion of receptor for hyaluronan-mediated motility (Rhamm) attenuates the formation of aggressive fibromatosis (desmoid tumor).
- Gαs proteins activate p72(Syk) and p60-c-Src tyrosine kinases to mediate sickle red blood cell adhesion to endothelium via LW-αvβ3 and CD44-CD44 interactions.
- HIV-1 infection-induced apoptotic microparticles inhibit human DCs via CD44.
- Hedgehog signaling antagonist promotes regression of both liver fibrosis and hepatocellular carcinoma in a murine model of primary liver cancer.
- High-resolution microrheology in the pericellular matrix of prostate cancer cells.
- Hyaluronan fragments contribute to the ozone-primed immune response to lipopolysaccharide.
- In vitro culture of human peripheral blood monocytes induces hyaluronan binding and up-regulates monocyte variant CD44 isoform expression.
- Inhibition of HIV type 1 infection of mononuclear phagocytes by anti-CD44 antibodies.
- Intracameral Delivery of Layer-by-Layer Coated siRNA Nanoparticles for Glaucoma Therapy.
- Intravascular bronchioloalveolar tumor of the lung presenting as pulmonary thromboembolic disease and pulmonary hypertension.
- Leukocyte phenotypic changes in an in vitro model of ABO hemolytic transfusion reaction.
- Lutheran antigens, CD44-related antigens, and Lutheran regulatory genes.
- Lyphocyte migration in L-selectin-deficient mice. Altered subset migration and aging of the immune system.
- MEK1/2 inhibitors reverse acute vascular occlusion in mouse models of sickle cell disease.
- MIF allele-dependent regulation of the MIF coreceptor CD44 and role in rheumatoid arthritis.
- Measurement of an adhesion molecule as an indicator of inflammatory disease activity. Up-regulation of the receptor for hyaluronate (CD44) in rheumatoid arthritis.
- Monocyte adhesion in patients with bone marrow fibrosis is required for the production of fibrogenic cytokines. Potential role for interleukin-1 and TGF-beta.
- Myoepithelial-specific CD44 shedding contributes to the anti-invasive and antiangiogenic phenotype of myoepithelial cells.
- Myoepithelial-specific CD44 shedding is mediated by a putative chymotrypsin-like sheddase.
- N-terminal and central regions of the human CD44 extracellular domain participate in cell surface hyaluronan binding.
- Osteopontin increases CD44 expression and cell adhesion in RAW 264.7 murine leukemia cells.
- Osteopontin inhibits expression of cytochrome c oxidase in RAW 264.7 murine macrophages.
- Osteopontin-dependent CD44v6 expression and cell adhesion in HepG2 cells.
- Proteolytic activity and immunogenicity of oral bromelain within the gastrointestinal tract of mice.
- Pten loss and RAS/MAPK activation cooperate to promote EMT and metastasis initiated from prostate cancer stem/progenitor cells.
- Quinocarmycin analog DX-52-1 inhibits cell migration and targets radixin, disrupting interactions of radixin with actin and CD44.
- RAG2:GFP knockin mice reveal novel aspects of RAG2 expression in primary and peripheral lymphoid tissues.
- Regulation of human CD44H and CD44E isoform binding to hyaluronan by phorbol myristate acetate and anti-CD44 monoclonal and polyclonal antibodies.
- Role of adhesion molecules in the pathogenesis of rheumatoid arthritis.
- Role of hyaluronan and hyaluronan-binding proteins in human asthma.
- Secreted osteopontin from CD4+ T cells limits acute graft-versus-host disease.
- Selective expression of CD44, a putative prostate cancer stem cell marker, in neuroendocrine tumor cells of human prostate cancer.
- Serum levels of soluble CD44 in primary Sjögren's syndrome.
- Serum protein expression predicts recurrence in patients with early-stage lung cancer after resection.
- Sickle red cells induce adhesion of lymphocytes and monocytes to endothelium.
- Single-nucleotide polymorphisms of stemness genes predicted to regulate RNA splicing, microRNA and oncogenic signaling are associated with prostate cancer survival.
- Stage-specific functions of E-proteins at the β-selection and T-cell receptor checkpoints during thymocyte development.
- Stem-like epithelial cells are concentrated in the distal end of the fallopian tube: a site for injury and serous cancer initiation.
- Steroid induction of therapy-resistant cytokeratin-5-positive cells in estrogen receptor-positive breast cancer through a BCL6-dependent mechanism.
- Suppression of inflammatory corneal lymphangiogenesis by application of topical corticosteroids.
- TNFalpha and IL-4 regulation of hyaluronan binding to monocyte CD44 involves posttranslational modification of CD44.
- The JAK2/STAT3 signaling pathway is required for growth of CD44⁺CD24⁻ stem cell-like breast cancer cells in human tumors.
- The Prognostic Value of CD44 Expression in Epithelial-Mesenchymal Transition: Preliminary Data from Patients with Gastric and Esophageal Cancer.
- The Role of CD44 in Glucose Metabolism in Prostatic Small Cell Neuroendocrine Carcinoma.
- The role of hyaluronic acid in atherosclerosis and intimal hyperplasia.
- The transmembrane hyaluronate receptor (CD44): multiple functions, multiple forms.
- Tumor initiating cells in esophageal squamous cell carcinomas express high levels of CD44.
- [Expression of presenilin 1 on the cell surface in motile polarized cells].
- sCD44 overexpression increases intraocular pressure and aqueous outflow resistance.
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Keywords of People
- Gunn, Michael Dee, Professor of Medicine, Immunology
- Zennadi, Rahima, Associate Professor in Medicine, Pathology